1. A COVID-19 perspective of multiple evanescent white dot syndrome (MEWDS).
- Author
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Kashyap, Himanshu, Manoharan, Anitha, Mahendradas, Padmamalini, Agarwal, Aniruddha, and Majumder, Parthopratim Dutta
- Subjects
BOOSTER vaccines ,COVID-19 ,COVID-19 vaccines ,IRIDOCYCLITIS ,SYNDROMES ,UVEITIS - Abstract
Multiple evanescent white dot syndrome (MEWDS) is a rare form of posterior uveitis characterized by involvement in the posterior pole and mid-periphery. A viral etiology that provokes an immune-mediated response has been hypothesized to be the inciting factor of the pathology. Recently, there has been an increase in the literature regarding new-onset uveitis and reactivation of previously diagnosed cases of uveitis following COVID-19 vaccinations. The COVID-19 vaccination has been speculated to trigger an immunomodulatory shift in recipients, resulting in an autoimmune event. MEWDS following COVID-19 vaccination was reported in 31 patients. It was most commonly observed following the first dose, affecting 15 patients, and least commonly after the booster dose, in only one patient. MEWDS-like disease following anti-SARS-CoV-2 vaccinations was reported the most in 16 cases after the Pfizer-BioNTech vaccination (BNT162b2 mRNA). Most of these cases had Primary MEWDS without any previous history of a similar event in the past. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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