1. Spectroscopic correlation and role of Azathioprine in long-term remission in patients of Hashimoto encephalopathy.
- Author
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Singh, Harpreet, Ray, Sucharita, Agarwal, Shalini, Pal Verma, Raj, Talapatra, Paulomi, and Gupta, Vikas
- Subjects
AUTOIMMUNE thyroiditis ,AZATHIOPRINE ,BRAIN ,ELECTROENCEPHALOGRAPHY ,NUCLEAR magnetic resonance spectroscopy ,DISEASE remission ,DIAGNOSIS ,THERAPEUTICS - Abstract
Hashimoto encephalopathy remains a Rubik's cube for the present generation of clinical research. Myriad presentations have been noted, and observations recorded in few subgroups of patients have gone on only to be trashed by a second group of patients with a completely different clinical profile. Steroids have been traditionally held to be the treatment for this condition, but long-term side effects associated with it limits its use. Although multiple drugs have been tried, yet there exists no data for their long-term efficacy in maintaining remission. No radiological findings have been consistently associated with this condition. We report the use of azathioprine in maintaining long-term remission in one such patient with Hashimoto encephalopathy and the presence of lactate peak in magnetic resonance spectroscopy of the patient, which showed dramatic regression with institution of immunosuppression. [ABSTRACT FROM AUTHOR]
- Published
- 2013
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