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Aim: The study aimed at developing a scoring system for scintigraphic grading of gastro-esophageal reflux (GER), on gastro-esophageal reflux scintigraphy (GERS) and comparison of clinical and scintigraphic scores, pre- and post-treatment. Materials and Methods: A total of 39 cases with clinically symptomatic GER underwent 99mTc sulfur colloid GERS; scores were assigned based on the clinical and scintigraphic parameters. Post domperidone GERS was performed after completion of treatment. Follow up GERS was performed and clinical and scintigraphic parameters were compared with baseline parameters. Results: Paired t-test on pre and post domperidone treatment clinical scores showed that the decline in post-treatment scores was highly significant, with P value < 0.001. The scintigraphic scoring system had a sensitivity of 93.9% in assessing treatment response to domperidone, specificity of 83.3% i.e., 83.3% of children with no decline in scintigraphic scores show no clinical response to Domperidone. The scintigraphic scoring system had a positive predictive value of 96.9% and a negative predictive value of 71.4%. Conclusion: GERS with its quantitative parameters is a good investigation for assessing the severity of reflux and also for following children post-treatment. [ABSTRACT FROM AUTHOR]

The article presents a study which examines the pediatric liver transplantation in India. The study uses the analysis of 28 end-stage liver disease (ESLD) children wherein 26 children received liver transplantation procedure since 2005, and the two children underwent cadaveric grafts. The study shows that biliary atresia is presented as the most common indication of ESLD, while the common complications of the liver transplantation include infections, acute rejection, and renal failure.