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Purpose: To compare the effectiveness of pencil push-up therapy (PPT) versus office-based vision therapy in patients with convergence insufficiency. Materials and Methods: In this study, 60 students from Zahedan University of Medical Sciences with convergence insufficiency were selected. After determining their refractive error (with a retinoscope), near point of convergence (by millimeter ruler), near heterophoria (by alternate prism cover test), and positive fusional vergence at near (by prism bar), subjects were divided into two groups to receive PPT (at least three times a day for 5 minutes each time) or office-based therapy (two times each week for 60 minutes each visit) without home reinforcement. Subjects were re-examined 4 and 8 weeks after initiation of treatment. Statistical analysis was performed with the independent samples t-test and the analysis of variance (ANOVA). Statistical significance was indicated by P < 0.05. Results: The near point of convergence, phoria, and positive fusional vergence were not statistically different between the two groups before treatment (P > 0.05). After 4 and 8 weeks of therapy, only the positive fusional vergence was statistically significantly different between groups (P = 0.001). Results from ANOVA indicated a considerable difference between the two groups in general but the observed difference was related only to positive fusional vergence. Conclusion: PPT and office-based vision therapy are comparable for treatment of convergence insufficiency. While we do not deny the more efficacious nature of office-based therapy, it is not always practical, may be too expensive, and may not be locally available. A home-based therapy offers a cost-effective reasonable alternative. [ABSTRACT FROM AUTHOR]