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Start Over Author "Baixiang Li" Publisher wolters kluwer india pvt ltd
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1. Aluminum neurotoxicity effects on intracellular Ca2+ homeostasis in the rat cerebral cortex.

Author

Rui Ren, Yang Zhang, Xiaofeng Zhang, Yanping Wu, Dandan Zhang, and Baixiang Li

Abstract

The article presents a study that deals with binding of aluminum ion (Al3+) with calmodulin (CaM) and calcium ions (Ca2+). The binding led to loss of capacity of CaM to bind to Ca2+, leading to increased [Ca2+]i. The study cites the role of Al3 in promoting calcium release from organelles by stimulating L-Ca2+ α1c to trigger calcium-induced calcium release.

Published
2010
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