1. Renal Profile of Herbal Medicine Users and Nonusers: An Exploratory Cross-sectional Study in a Family Medicine Clinic in Nigeria.
- Author
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Maiyegun, Afisulahi Abiodun, Akangoziri, Mark Divine, Grema, Bukar Alhaji, Mutalub, Yahkub Babatunde, and Ibrahim, Farida Buhari
- Subjects
GLOMERULAR filtration rate ,HERBAL medicine ,KIDNEY physiology ,TEACHING hospitals ,ALBUMINURIA - Abstract
Context: A major risk of herbal medicine is the potential for toxicity and serious side effects. Unlike orthodox medicine, herbs are usually consumed without prior safety assessment via clinical studies. This means that the clinical effects of herbs may be detected only through an assessment of the health parameters of consumers. Aim: The study aimed to evaluate participants' renal profiles, comparing that of herb users with nonusers, thereby identifying any differences between the two groups. Settings and Design: It is a cross-sectional, analytic study among adult patients attending the general outpatient unit of Abubakar Tafawa Balewa University Teaching Hospital, Bauchi, Nigeria. Materials and Methods: The study assessed and compared estimated glomerular filtration rate, microalbuminuria, and proteinuria among patients who reported using herbs and those who did not report any use. Statistical Analysis: Data were analyzed using Epi Info 7.2. Results: Three hundred and forty-one participants were enrolled. The mean eGFR was 87.47 ± 25.44 ml/min/1.73 m
2 for participants who used herbs and 84.76 ± 25.49 ml/min/1.73 m2 for those who never used herbs (P value 0.48). Among all participants, proteinuria ≥0.3 g/l was present in 29 (8.50%) and microalbuminuria ≥30 mg/l in 138 (40.47%). There was no statistically significant difference in the renal parameters of both groups. Conclusion: The study found no evidence of the harmful effect of the herbs reported on kidney function. This could be because that the study participants mainly reported using edible—and, therefore, presumably safe—herbs. Further studies in human subjects of the effect of herbal medicine on the kidney and other systems are suggested. [ABSTRACT FROM AUTHOR]- Published
- 2024
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