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Background: Dyslipidemia is one of the modifiable risk factors of coronary heart disease. Objective: To determine the pattern of dyslipidemia among rural population. Methodology: This was a cross sectional study conducted in rural area of Rahim Yar Khan as a part of large study regarding prevalence of coronary heart disease. A total of 2000 study subjects were included by systematic random sampling technique, from 22 clusters of subdistricts, Rahim Yar khan, Pakistan. Patients excluded from study were; on statin therapy, patients with hypothyroidism, diabetes mellitus. Informed verbal consent was taken form each patient. Fasting venous blood samples was taken for serum total cholesterol level, serum triglycerides level, low density lipoprotein (LDL) and high-density lipoprotein (HDL). Lipid profile was considered deranged if any one of the followings was present: Total Cholesterol level >200mg/dl, Triglyceride (TG) level >150mg/dl, High density lipoprotein (HDL) 130 mg/dl. Data was entered and analyzed using computer program SPSS version 16.0. Results: A total of 2000 study subjects were included in this study, with male 792(39.6%) and females 1208 (60.4%). Mean age of study subjects was 46±9.6 years. Overall 843 (42%) study subjects have deranged lipids, with 26 (1.3%) having high LDLc, 45 (2.2%) having high cholesterol, 375 (18.8%) having high triglycerides and 538 (27%) low HDLc. Conclusion: This study showed that there was high frequency of deranged lipids among general population of rural background. Most common component among deranged lipids were low HDLc, followed by high triglycerides, high cholesterol and high LDLc. Key Words: Dyslipidemia, Rural population, Prevalence