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Your search keyword '"Hypnotics and Sedatives isolation & purification"' showing total 5 results
Start Over Descriptor "Hypnotics and Sedatives isolation & purification" Publisher zhongguo yao xue hui : zhongguo zhong yi yan jiu yuan zhong yao yan jiu suo
5 results on '"Hypnotics and Sedatives isolation & purification"'

1. [Hypnotic effect of Chinese materia medica Cynanchum chinese in mice].

Author

Peng XD, Yan QS, Wang R, Yang WD, and Peng JZ

Subjects
Animals, Central Nervous System drug effects, Central Nervous System physiology, Chloroform, Dose-Response Relationship, Drug, Drug Synergism, Drugs, Chinese Herbal isolation & purification, Drugs, Chinese Herbal toxicity, Female, Hypnotics and Sedatives isolation & purification, Male, Mice, Mice, Inbred ICR, Pentobarbital pharmacology, Plants, Medicinal chemistry, Random Allocation, Water, Cynanchum chemistry, Drugs, Chinese Herbal pharmacology, Hypnotics and Sedatives pharmacology, Motor Activity drug effects, Sleep drug effects
Abstract

Objective: To study the central pharmacological effect of the water and chloroform-extract compounds from C. chinese in mice., Method: The independent activity test and the hypnotic synergism test by sub-threshold hypnotic dosage of pentobarbital were employed to evaluate the central pharmacological effect of the extract-compounds, and the minimal neurotoxicity was evaluated by the rotorod test., Result: the extract-compounds exhibited significant dose-related inhibition effect of the spontaneous motor activity in mice after intraperitoneal administration. And the two extract-compounds promoted the hypnotic effect by sub-threshold hypnotic dosage administration of pentobarbital, and produced ED50 value of 2.36 g kg (-1) and 0.75 g kg(-1), respectively. Also, both extract-compounds showed no neurotoxicity in the experiment., Conclusion: The extract compounds from C. chinese showed inhibitional effect on CNS.

Published
2007

2. [Species of Ligularia in the northwestern China and their medicinal uses].

Author

Liu SJ, Qi HY, Qi H, Zhang M, and Wang ZT

Subjects
Anti-Asthmatic Agents isolation & purification, Anti-Asthmatic Agents pharmacology, Antitussive Agents isolation & purification, Antitussive Agents pharmacology, China, Conservation of Natural Resources, Drugs, Chinese Herbal isolation & purification, Drugs, Chinese Herbal pharmacology, Ecosystem, Humans, Hypnotics and Sedatives isolation & purification, Hypnotics and Sedatives pharmacology, Asteraceae chemistry, Asteraceae classification, Pharmacognosy, Plants, Medicinal chemistry, Plants, Medicinal classification
Abstract

Objective: To investigate the species of Ligularia distributed in the northwestern China and their medicinal uses in the local area., Method: Field investigation, specimen collection, taxonomic study and datum check were adopted., Result: There are 29 species and 1 varieties of Ligularia distributed in the northwestern China, and 18 species of them had been used as folk medicines with the function of resolving phlegm, relieving cough, clearing heat and toxins., Conclusion: The northwestern China is abundant in medicinal resource of Ligularia.

Published
2006

3. [Advances in study on bark of Albizzia julibrissin].

Author

Yu DH, Qiao SY, and Zhao YM

Subjects
Animals, Antineoplastic Agents, Phytogenic isolation & purification, Antineoplastic Agents, Phytogenic pharmacology, Flavones chemistry, Flavones isolation & purification, Humans, Hypnotics and Sedatives isolation & purification, Molecular Structure, Plant Bark chemistry, Reproductive Control Agents isolation & purification, Reproductive Control Agents pharmacology, Triterpenes chemistry, Albizzia chemistry, Hypnotics and Sedatives pharmacology, Plants, Medicinal chemistry, Triterpenes isolation & purification
Abstract

Cortex Albizziae, the stem bark of the leguminous plant Albizzia julibrissin, is specified in Chinese pharmacopoeia as a traditional Chinese medicine used to relieve melancholia and uneasiness of body and mind, invigorate the circulation of blood and subside a swelling. This article reviews the recent advances in chemical constituents and pharmacological activities of Cortex Albizziae.

Published
2004

4. [A dynamic study on inhibitory effect of palustrine on mg2(+)-ATpase and Ca2(+)-ATPase of brain synaptic vesicle membrane in rats].

Author

Ji Y, Wang Y, Tai B, and Chang F

Subjects
Alkaloids isolation & purification, Animals, Drugs, Chinese Herbal chemistry, Female, Hypnotics and Sedatives isolation & purification, Male, Rats, Rats, Sprague-Dawley, Alkaloids pharmacology, Brain enzymology, Ca(2+) Mg(2+)-ATPase metabolism, Calcium-Transporting ATPases metabolism, Hypnotics and Sedatives pharmacology, Synaptic Vesicles enzymology
Published
1996

5. [Sedative chemical constituents of leaves of Apocynum venetum Linn].

Author

Chen M and Liu F

Subjects
Quercetin isolation & purification, Alkaloids isolation & purification, Coumarins, Drugs, Chinese Herbal chemistry, Hypnotics and Sedatives isolation & purification, Quercetin analogs & derivatives
Abstract

Eight constituents were isolated from the ether solvent fraction of leaves of Apocynum venetum and identified as triacontanol, beta-sitosterol, quercetin, hyperin, long-chain fatty acids (C28-C34), lupeol, scopoletin and isofraxidin. Isofraxidin and hyperin were effective sedative components.

Published
1991

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