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146 results on '"AGABITI‐ROSEI, E."'

17. Reliability and limitations of echocardiographic measurement of left ventricular mass for risk stratification and follow-up in single patients: the RES trial. Working Group on Heart and Hypertension of the Italian Society of Hypertension. Reliability of M-mode Echocardiographic Studies.

Author

de Simone G, Muiesan ML, Ganau A, Longhini C, Verdecchia P, Palmieri V, Agabiti-Rosei E, Mancia G, de Simone, G, Muiesan, M L, Ganau, A, Longhini, C, Verdecchia, P, Palmieri, V, Agabiti-Rosei, E, and Mancia, G

Published
1999
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24. Serum uric acid and its relationship with metabolic syndrome and cardiovascular risk profile in patients with hypertension: Insights from the I-DEMAND study.

Author

Viazzi, F., Garneri, D., Leoncini, G., Gonnella, A., Muiesan, M. L., Ambrosioni, E., Costa, F. V., Leonetti, G., Pessina, A. C., Trimarco, B., Volpe, M., Agabiti Rosei, E., Deferrari, G., and Pontremoli, R.

Abstract

Background and aims The independent role of serum uric acid (SUA) as a marker of cardio-renal risk is debated. The aim of this study was to assess the relationship between SUA, metabolic syndrome (MS), and other cardiovascular (CV) risk factors in an Italian population of hypertensive patients with a high prevalence of diabetes. Methods and results A total of 2429 patients (mean age 62 ± 11 years) among those enrolled in the I-DEMAND study were stratified on the basis of SUA gender specific quartiles. MS was defined according to the NCEP-ATP III criteria, chronic kidney disease (CKD) as an estimated GFR (CKD-Epi) <60 ml/min/1.73 m² or as the presence of microalbuminuria (albumin-to-creatinine ratio ≥2.5 mg/mmol in men and ≥3.5 mg/mmol in women). The prevalence of MS, CKD, and positive history for CV events was 72%, 43%, and 20%, respectively. SUA levels correlated with the presence of MS, its components, signs of renal damage and worse CV risk profile. Multivariate logistic regression analysis revealed that SUA was associated with a positive history of CV events and high Framingham risk score even after adjusting for MS and its components (OR 1.10, 95% CI 1.03-1.18; P = 0.0060; OR 1.28, 95% CI 1.15-1.42; P < 0.0001). These associations were stronger in patients without diabetes and with normal renal function. Conclusions Mild hyperuricemia is a strong, independent marker of MS and high cardio-renal risk profile in hypertensive patients under specialist care. Intervention trials are needed to investigate whether the reduction of SUA levels favorably impacts outcome in patients at high CV risk. [ABSTRACT FROM AUTHOR]

Published
2014
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25. Identification of the hemodynamic modulators and hemodynamic status in uncontrolled hypertensive patients.

Author

Viigimaa, M., Talvik, A., Wojciechowska, W., Kawecka-Jaszcz, K., Toft, I., Stergiou, G. S., Nasothimiou, E. G., Kotsis, V., Agabiti Rosei, E., Salvetti, M., Dorobantu, M., Martell-Claros, N., Abad-Cardiel, M., Hernández-Hernández, R., Doménech, M., and Coca, A.

Subjects
BLOOD pressure, HYPERTENSION, ANTIHYPERTENSIVE agents, VASOCONSTRICTORS, HEMODYNAMICS
Abstract

Only 20-30% out of the treated hypertensive patients in Europe are achieving blood pressure (BP) control. Among other recognized factors, these poor results could be attributable to the fact that for many doctors it is very difficult to detect which is the predominant hemodynamic cause of the hypertension (hypervolemia, hyperinotropy or vasoconstriction). The aim of the study was to use non-invasive thoracic electrical bioimpedance (TEB) to evaluate hemodynamic modulators and subsequent hemodynamic status in uncontrolled hypertensive patients, receiving at least two antihypertensive drugs. A number of 134 uncontrolled hypertensive patients with essential hypertension were evaluated in nine European Hypertension Excellence centers by means of TEB (the HOTMAN® System). Baseline office systolic and diastolic BP averaged 156/92 mmHg. Hemodynamic measurements show that almost all patients (98.5%) presented at least one altered hemodynamic modulator: intravascular hypervolemia (96.4%) and/or hypoinotropy (42.5%) and/or vasoconstriction (49.3%). Eleven combinations of hemodynamic modulators were present in the study population, the most common being concomitant hypervolemia, hypoinotropy and vasoconstriction in 51(38%) patients. Six different hemodynamic states (pairs of mean arterial pressure and stroke index) were found. Data suggest that there is a strong relation between hypertension and abnormal hemodynamic modulators. This method might be helpful for treatment individualization of hypertensive patients. [ABSTRACT FROM AUTHOR]

Published
2013
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26. Pulsatile hemodynamics and microcirculation: evidence for a close relationship in hypertensive patients.

Author

Muiesan ML, Salvetti M, Rizzoni D, Paini A, Agabiti-Rosei C, Aggiusti C, Bertacchini F, Stassaldi D, Gavazzi A, Porteri E, De Ciuceis C, Agabiti-Rosei E, Muiesan, Maria Lorenza, Salvetti, Massimo, Rizzoni, Damiano, Paini, Anna, Agabiti-Rosei, Claudia, Aggiusti, Carlo, Bertacchini, Fabio, and Stassaldi, Deborah

Abstract

The possible relationships between indicators of small resistance artery structure and of arterial stiffness and central hemodynamics have not yet been evaluated. Aim of this study was to assess the relationship between indicators of large arteries stiffness, including carotido-femoral pulse wave velocity and of vascular alterations in small resistance arteries (media/lumen ratio, M/L) in patients with primary and secondary hypertension. In 73 patients (mean age, 53±14 years, 34 females, 25 with type 2 diabetes mellitus, 18 never treated) with essential (n=37) and secondary (n=36) hypertension, carotido-femoral pulse wave velocity was measured. In all patients, small resistance arteries were dissected from subcutaneous fat biopsies and mounted on an isometric myograph, for the measurement of the M/L. Pulse wave analysis was performed in 67 patients. M/L ratio was significantly related to brachial systolic blood pressure and pulse pressure (r=0.36 and 0.31, P<0.001, respectively) and to central systolic and pulse pressure (r=0.44 and 0.42, P<0.001, respectively). A positive correlation was observed between M/L ratio and carotido-femoral pulse wave velocity (r=0.45; P<0.001); this correlation remained statistically significant after adjustment for age and mean blood pressure. M/L ratio was also associated to aortic augmentation index (r=0.33; P=0.008), and this correlations remained statistically significant after adjustment for potential confounders. In hypertensive patients, the presence of structural alterations of small resistance arteries may be associated with the increase in large arteries stiffness and possibly contribute to an increase in central pressure by increasing the magnitude of wave reflections. [ABSTRACT FROM AUTHOR]

Published
2013
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34. Inappropriate left ventricular mass: Reliability and limitations of echocardiographic measurement for risk stratification and follow-up in single patients.

Author

Muiesan ML, de Simone G, Ganau A, Longhini C, Verdecchia P, Mancia G, Agabiti-Rosei E, Working Group on Heart and Hypertension of Italian Society of Hypertension, Muiesan, M Lorenza, de Simone, Giovanni, Ganau, Antonello, Longhini, Carlo, Verdecchia, Paolo, Mancia, Giuseppe, and Agabiti-Rosei, Enrico

Published
2006
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35. Cardiac structural and functional changes during long-term antihypertensive treatment with lacidipine and atenolol in the European Lacidipine Study on Atherosclerosis (ELSA).

Author

Agabiti-Rosei E, Trimarco B, Muiesan ML, Reid J, Salvetti A, Tang R, Hennig M, Baurecht H, Parati G, Mancia G, Zanchetti A, ELSA (European Lacidipine Study on Atherosclerosis). Echocardiographic Substudy Group, Agabiti-Rosei, Enrico, Trimarco, Bruno, Muiesan, Maria Lorenza, Reid, John, Salvetti, Antonio, Tang, Rong, Hennig, Michael, and Baurecht, Hansjörg

Published
2005
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38. Comparative effects of candesartan and enalapril on left ventricular hypertrophy in patients with essential hypertension: the candesartan assessment in the treatment of cardiac hypertrophy (CATCH) study.

Author

Cuspidi C, Muiesan ML, Valagussa L, Salvetti M, Di Biagio C, Agabiti-Rosei E, Magnani B, Zanchetti A, Candesartan Assessment in the Treatment of Cardiac Hypertrophy Investigators, Cuspidi, Cesare, Muiesan, M Lorenza, Valagussa, Laura, Salvetti, Massimo, Di Biagio, Carlo, Agabiti-Rosei, Enrico, Magnani, Bruno, Zanchetti, Alberto, and CATCH investigators

Published
2002
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43. Perindopril versus captopril: Efficacy and acceptability in an Italian multi center trial.

Author

Agabiti-Rosei, E. and Ambrosioni, E.

Subjects
*THERAPEUTICS, *HYPERTENSION
Abstract

Compares the efficacy and acceptability of perindopril and captopril, given alone or in combination with a diuretic. Medical history of subjects; A multicenter, double-blind, randomized, parallel comparison study; Treatment and measurement s; Statistical analysis; Results; Effect on blood pressure and heart rate; Unwanted effects; Echocardiographic data; Final comments.

Published
1992
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44. Effects of long-term antihypertensive treatment with lisinopril on resistance arteries in hypertensive patients with left ventricular hypertrophy.

Author

Rizzoni, Damiano, Muiesan, Maria Lorenza, Porteri, Enzo, Castellano, Maurizio, Zulli, Roberto, Bettoni, Giorgio, Salvetti, Massimo, Monteduro, Cristina, Agabiti-Rosei, Enrico, Rizzoni, D, Muiesan, M L, Porteri, E, Castellano, M, Zulli, R, Bettoni, G, Salvetti, M, Monteduro, C, and Agabiti-Rosei, E

Published
1997
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47. Relationship between sympathetic nervous system activity, baroreflex and cardiovascular effects after acute nitric oxide synthesis inhibition in humans.

Author

Castellano, Maurizio, Rizzoni, Damiano, Beschi, Marina, Lorenza Muiesan, Maria, Porteri, Enzo, Bettoni, Giorgio, Salvetti, Massimo, Cinelli, Angelo, Zulli, Roberto, Agabiti-Rosei, Enrico, Castellano, M, Rizzoni, D, Beschi, M, Muiesan, M L, Porteri, E, Bettoni, G, Salvetti, M, Cinelli, A, Zulli, R, and Agabiti-Rosei, E

Published
1995
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48. Arterial spontaneous rhythmic contractile activity in humans and rats: spectral analysis and regulatory mechanisms.

Author

Rizzoni, Damiano, Castellano, Maurizio, Porteri, Enzo, Bettoni, Giorgio, Muiesan, Paolo, Muiesan, Maria Lorenza, Giulini, Stefano Maria, Cinelli, Angelo, Salvetti, Massimo, Rosei, Enrico Agabiti, Rizzoni, D, Castellano, M, Porteri, E, Bettoni, G, Muiesan, P, Muiesan, M L, Giulini, S M, Cinelli, A, Salvetti, M, and Agabiti Rosei, E

Published
1995
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