Search

Your search keyword '"Abate, Massimo Eraldo"' showing total 10 results
Start Over Author "Abate, Massimo Eraldo" Search Limiters Academic (Peer-Reviewed) Journals
10 results on '"Abate, Massimo Eraldo"'

1. Diagnostic and Dosimetry Features of [64Cu]CuCl2 in High-Grade Paediatric Infiltrative Gliomas

Author

Fiz, Francesco, Bottoni, Gianluca, Ugolini, Martina, Righi, Sergio, Cirone, Alessio, Garganese, Maria Carmen, Verrico, Antonio, Rossi, Andrea, Milanaccio, Claudia, Ramaglia, Antonia, Mastronuzzi, Angela, Abate, Massimo Eraldo, Cacchione, Antonella, Gandolfo, Carlo, Colafati, Giovanna Stefania, Garrè, Maria Luisa, Morana, Giovanni, and Piccardo, Arnoldo

Published
2023
Full Text
View/download PDF

3. Musculoskeletal manifestations of childhood cancer and differential diagnosis with juvenile idiopathic arthritis (ONCOREUM): a multicentre, cross-sectional study

Author

Amatruda, M, Atzeni, C, Bertolini, P, Bigucci, B, Caniglia, M, Cappella, M, Cattalini, M, Cefalo, MG, Cellini, M, Cortis, E, Davì, S, De Benedetti, F, Di Cataldo, A, Fabbri, E, Fagioli, F, Fontanili, I, Garaventa, A, Gicchino, MF, Ladogana, S, Locatelli, F, Magnolato, A, Marsili, M, Martino, S, Mascarin, M, Messina, C, Micalizzi, C, Porta, F, Rizzari, C, Civino, Adele, Alighieri, Giovanni, Prete, Eleonora, Caroleo, Anna Maria, Magni-Manzoni, Silvia, Vinti, Luciana, Romano, Micol, Santoro, Nicola, Filocamo, Giovanni, Belotti, Tamara, Santarelli, Francesca, Gorio, Chiara, Ricci, Francesca, Colombini, Antonella, Pastore, Serena, Cesaro, Simone, Barone, Patrizia, Verzegnassi, Federico, Olivieri, Alma Nunzia, Ficara, Monica, Miniaci, Angela, Russo, Giovanna, Gallizzi, Romina, Pericoli, Roberta, Breda, Luciana, Mura, Rossella, Podda, Rosa Anna, Onofrillo, Daniela, Lattanzi, Bianca, Tirtei, Elisa, Maggio, Maria Cristina, De Santis, Raffaela, Consolini, Rita, Arlotta, Annalisa, La Torre, Francesco, Mainardi, Chiara, Pelagatti, Maria Antonietta, Coassin, Elisa, Capolsini, Ilaria, Burnelli, Roberta, Tornesello, Assunta, Soscia, Francesca, De Fanti, Alessandro, Rigante, Donato, Pizzato, Cristina, De Fusco, Carmela, Abate, Massimo Eraldo, Roncadori, Andrea, Rossi, Elisa, Stabile, Giulia, Biondi, Andrea, Lepore, Loredana, Conter, Valentino, Rondelli, Roberto, Pession, Andrea, and Ravelli, Angelo

Published
2021
Full Text
View/download PDF

6. Diagnostic and Dosimetry Features of [64Cu]CuCl2 in High-Grade Paediatric Infiltrative Gliomas.

Author

Fiz, Francesco, Bottoni, Gianluca, Ugolini, Martina, Righi, Sergio, Cirone, Alessio, Garganese, Maria Carmen, Verrico, Antonio, Rossi, Andrea, Milanaccio, Claudia, Ramaglia, Antonia, Mastronuzzi, Angela, Abate, Massimo Eraldo, Cacchione, Antonella, Gandolfo, Carlo, Colafati, Giovanna Stefania, Garrè, Maria Luisa, Morana, Giovanni, and Piccardo, Arnoldo

Subjects
COPPER, GLIOMA treatment, TUMOR diagnosis, RADIATION dosimetry, RADIOPHARMACEUTICALS, COMPUTER algorithms
Abstract

Purpose of the Report: Paediatric diffuse high-grade gliomas (PDHGG) are rare central nervous system neoplasms lacking effective therapeutic options. Molecular imaging of tumour metabolism might identify novel diagnostic/therapeutic targets. In this study, we evaluated the distribution and the dosimetry aspects of [64Cu]CuCl2 in PDHGG subjects, as copper is a key element in cellular metabolism whose turnover may be increased in tumour cells. Material and Methods: Paediatric patients with PDHGG were prospectively recruited. [64Cu]CuCl2 PET/CT was performed 1 h after tracer injection; if the scan was positive, it was repeated 24 and 72 h later. Lesion standardised uptake value (SUV) and target-to-background ratio (TBR) were calculated. Tumour and organ dosimetry were computed using the MIRD algorithm. Each patient underwent an MRI scan, including FLAIR, T2-weighted and post-contrast T1-weighted imaging. Results: Ten patients were enrolled (median age 9, range 6–16 years, 6 females). Diagnoses were diffuse midline gliomas (n = 8, 5 of which with H3K27 alterations) and diffuse hemispheric gliomas (n = 2). Six patients had visible tracer uptake (SUV: 1.0 ± 0.6 TBR: 5 ± 3.1). [64Cu]CuCl2 accumulation was always concordant with MRI contrast enhancement and was higher in the presence of radiological signs of necrosis. SUV and TBR progressively increased on the 24- and 72-h acquisitions (p < 0.05 and p < 0.01, respectively). The liver and the abdominal organs received the highest non-target dose. Conclusions: [64Cu]CuCl2 is a well-tolerated radiotracer with reasonably favourable dosimetric properties, showing selective uptake in tumour areas with visible contrast enhancement and necrosis, thus suggesting that blood–brain barrier damage is a pre-requisite for its distribution to the intracranial structures. Moreover, tracer uptake showed an accumulating trend over time. These characteristics could deserve further analysis, to determine whether this radiopharmaceutical might have a possible therapeutic role as well. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

7. Post-Relapse Survival in Patients With Ewing Sarcoma

Author

Ferrari, Stefano, Luksch, Roberto, Hall, Kirsten Sundby, Fagioli, Franca, Prete, Arcangelo, Tamburini, Angela, Tienghi, Amelia, DiGirolamo, Stefania, Paioli, Anna, Abate, Massimo Eraldo, Podda, Marta, Cammelli, Silvia, Eriksson, Mikael, and Brach del Prever, Adalberto

Published
2015
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results