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Simple Summary: This systematic review and meta-analysis examines the impact of cancer and its treatment on orthodontic treatment success. Existing studies show significant gaps in understanding the relationship between anti-cancer medications and orthodontic care, necessitating further research. The review selected five studies with varying methodologies, finding a strong association between radiotherapy, antineoplastic drugs, and reduced success in orthodontic treatment. The results indicate that while orthodontic treatments can be effective for children undergoing chemotherapy, their effectiveness may diminish in older populations. The review underscores the importance of considering cancer therapies in orthodontic planning to optimize results and minimize complications. Background: There are several significant gaps in current studies of the relationship between anti-cancer medications and orthodontic care that call for more investigation. As a result, the main goals of this systematic review and meta-analysis were to summarise and assess the information that was available regarding the effect of radiotherapy and anti-cancer medications on the overall successful completion of an orthodontic treatment plan. Methods: A standardised data extraction form was devised in accordance with the PRISMA guidelines to conduct a systematic review and meta-analysis, with specific criteria implemented for selecting studies with low to moderate risk of bias. Results: Five studies involving different methodologies were selected at the conclusion of the search strategy. The statistical analysis revealed an estimated odds ratio (OR) of 0.31 and relative risk (RR) of 0.48, indicating a statistically significant association between the use of radiotherapy and anti-neoplastic drugs and a noticeable reduction in the successful completion of orthodontic treatment. The heterogeneity analysis showed significant heterogeneity among the studies. Conclusions: This review emphasises that, although orthodontic therapies can still be beneficial for children receiving chemotherapy, the effectiveness of the therapy may be diminished in older populations. The findings further highlight how crucial it is to take cancer therapies into account when planning and managing orthodontic treatment in order to optimise results and reduce problems. [ABSTRACT FROM AUTHOR]

Background: Orthognathic surgery is a surgical procedure performed to correct severe jaw misalignments that can affect a patient's facial aesthetics and functional occlusion. While the primary goal of orthognathic surgery is to improve functional outcomes and facial appearance, it is essential to assess patient satisfaction as a crucial aspect of overall treatment success. Materials and Methods: Patient selection: We conducted a prospective study involving 50 patients who underwent orthognathic surgery. All patients had a confirmed diagnosis of severe jaw misalignment, as determined by clinical and radiographic assessments. The surgical procedures performed included maxillary advancement, mandibular setback, or a combination of both, depending on the patient's specific diagnosis. Preoperative orthodontic treatment was provided to align the teeth and prepare the patient for surgery. Patients were evaluated preoperatively and at postoperative intervals of 3 months, 6 months, and 1 year. Results: Patient satisfaction scores and functional outcomes were as follows: aesthetics of facial profile (1-year post-op): mean score = 4.6, chewing function (1-year post-op): mean score = 4.4, speech function (1-year post-op): mean score = 4.3, and overall satisfaction with surgical outcome (1-year post-op): mean score = 4.5. Objective assessments revealed a significant improvement in occlusion and facial aesthetics. The mean reduction in overjet was 4.8 mm, and the mean reduction in overbite was 3.2 mm. Additionally, the mean postoperative ANB angle improved by 3.7°, indicating a better facial balance. Conclusion: Orthognathic surgery in our cohort of 50 patients resulted in high levels of patient satisfaction with both functional outcomes and facial aesthetics. Objective measurements also indicated significant improvements in occlusion and facial balance. [ABSTRACT FROM AUTHOR]

Background: Maxillary crowding is a common orthodontic issue that can impact a patient's oral health and overall well-being. The timing of orthodontic treatment plays a crucial role in achieving optimal results. Materials and Methods: Thirty patients who received early intervention with palatal expansion (Group A) and 30 patients who underwent late orthodontic treatment (Group B) were included in this study. The age range for Group A was 8–10 years, while Group B had an age range of 16–18 years. Pretreatment and posttreatment records, including dental models and cephalometric radiographs, were analyzed to assess the effectiveness of the respective treatments. Results: In Group A, the mean duration of treatment was 12 months, and the maxillary crowding was corrected by an average of 4.5 mm. In Group B, the mean treatment duration was 24 months, and maxillary crowding was corrected by an average of 3.2 mm. The early intervention group (Group A) exhibited a statistically significant reduction in treatment duration and greater correction of maxillary crowding compared to the late orthodontic treatment group (Group B) (P < 0.05). Conclusion: Early intervention with palatal expansion is an effective approach for correcting maxillary crowding, leading to shorter treatment duration and greater improvement compared to late orthodontic treatment. [ABSTRACT FROM AUTHOR]

Background: Class II malocclusions are a common dental issue characterized by the misalignment of the upper and lower teeth. Early orthodontic treatment is often considered to correct these malocclusions, but its long-term effectiveness remains unclear. Materials and Methods: In this study, we examined the impact of early orthodontic treatment on the long-term stability of Class II malocclusions. We conducted a retrospective analysis of dental records from a sample of 150 patients who had received early orthodontic treatment for Class II malocclusions. The treatment involved braces and other orthodontic appliances. We compared their dental measurements before and after treatment, with a follow-up period of 5 years. Results: Our analysis revealed that the early orthodontic treatment led to a significant improvement in the alignment of upper and lower teeth, as indicated by a reduction in the overjet (the horizontal distance between upper and lower incisors). The mean overjet reduction was 3.2 millimeters. Furthermore, the Angle's Class II molar relationship was corrected in 80% of the cases. Conclusion: Early orthodontic treatment for Class II malocclusions demonstrated positive long-term stability, as evidenced by a reduction in overjet and improvement in molar relationships. [ABSTRACT FROM AUTHOR]

Infection control is essential to protect both the doctor and the patient by preventing the spread of infectious diseases. There is no exception in the field of dentistry, particularly in orthodontics, where numerous appliances are used for a variety of functions and also because the mouth cavity has the highest concentration of bacteria of any body part. Through this systematic review, we aimed to assess the various methods of sterilization employed in an orthodontic setting. Using relevant keywords, reference searches, and citation searches, the databases such as PubMed, MEDLINE, Web of Science, Cochrane, and Scopus were all searched; a total of 206 documents were found, of which 113 were initially selected. The remaining 23 distinct papers were initially made available after 90 publications that were identical to or similar to one another were eliminated. The final selection was made from eight documents that met all inclusion and exclusion requirements. The existing methods of sterilization were found to be competent in dealing with the microorganisms found in a typical orthodontic setting. The chemical method of sterilization was the norm in most of the studies that we assessed, with glutaraldehyde and peracetic acid (PAA) being the most commonly employed compounds for disinfection. [ABSTRACT FROM AUTHOR]

A variety of metals and alloys are employed in the field of orthodontics, primary of which happen to be the construction of wires. Through this systematic review, we aimed to assess the various metallurgical characteristics of the said metals and alloys. Four hundred and eighty‑two documents in total were found after a thorough search of the online journals, and 169 of the papers were initially chosen. Ultimately, 16 documents were selected that satisfied the necessary inclusion and exclusion criteria, primarily in vitro studies, literature reviews, and comparative analyses. NiTi alloy was found to be the most commonly used alloy in construction of orthodontic wires across all the studies that we had selected for our review. It also had better performance and consistency in terms of its usage as depicted by the meta‑analysis performed, with stainless steel wires being a close second primarily due to its lesser cost compared to the former. Metallurgy and orthodontics are inextricably linked with one another. The various components of orthodontics such as wires, pliers, and other instruments utilize the metallurgical characteristics of metals and alloys that are specially prepared for the challenges of this field. [ABSTRACT FROM AUTHOR]

The nutritional needs already increased by adolescent growth, activity, and stress are further exacerbated by the physical, physiological, and psychological stress that orthodontic treatment causes. Hence, the main objective of this systematic review was to analyze the relationship between adequate nutrition and its impact on orthodontic treatment success rates. Using relevant keywords, reference searches, and citation searches, the databases such as PubMed–Medical Literature Analysis and Retrieval System Online, Web of Science, Cochrane, and Scopus were all searched. “Diet,” “Minerals,” “Nutrition,” “Orthodontics,” and “Vitamins” were the search terms used to scour the database. The 10 studies selected for the systematic review and subsequent meta‑analysis could not conclusively establish the correlation between proper nutrition and its impact on orthodontic treatment of the patient. There was virtually little connection between patients’ dietary intake and the effectiveness of their orthodontic treatment. Additionally, a direct causal link between the two could not be established legitimately because the majority of the studies reviewed only noted an impact during the early stages of the treatment [ABSTRACT FROM AUTHOR]

Background: The literature on the use of static magnetic field (SMF), particularly in orthodontics, has certain gaps. Furthermore, the mechanism by which SMF affects orthodontic tooth movement (OTM) is still unclear and quite contradictory. Thus, the goal of this systematic review and meta-analysis was to assess SMF's effect on OTM. This study also sought to analyse the variability of the studies included in the analysis and the size of the impact of SMF on OTM. Methods: Using the PRISMA guidelines, reviewers implemented a search strategy across several online databases, filtering out the initial articles that were obtained by applying relevant inclusion and exclusion criteria. Results: The overall effect size for the odds ratio was found to be 0.58, with a 95% confidence interval ranging from 0.40 to 0.86. This indicates that exposure to static magnetic fields is associated with a significantly reduced likelihood of orthodontic tooth movement in the animal studies analysed. Similarly, the overall effect size for the risk ratio was calculated to be 0.71, with a 95% confidence interval ranging from 0.55 to 0.91. The risk ratio also suggests a significant impact of SMF on OTM, with animals exposed to magnetic fields being at a lower risk of experiencing substantial tooth movement compared to those not exposed. However, it is important to note that moderate heterogeneity was observed among the included studies. Conclusion: The findings of this systematic review and meta-analysis indicate that there may be a causal relationship between OTM and SMF. However, the small number of studies included in this review and their poor methodological quality limit the available data, highlighting the need for further well-designed research to support these conclusions. [ABSTRACT FROM AUTHOR]

Background and objectives: Investigation into the impact of dental trauma on the results of orthodontic treatment is crucial because it can have a major influence on patient care. However, there has not yet been a thorough review or meta-analysis of the available data, which is inconsistent and scant. Therefore, the goal of this systematic review and meta-analysis is to investigate the impact of dental trauma on orthodontic parameters. Search methods and criterion of selection: Major online databases were searched (beginning from the year 2011) for relevant articles using a properly defined search strategy. Analysis protocol: Risk of bias (RoB) and the Cochrane risk of bias tool were utilized for the purposes of bias evaluation within the individual studies and within the review, respectively. Results: Out of the six clinical trials selected, a significant impact of trauma was observed in individuals in all but one paper. Gender predilection varied across studies and could not be conclusively determined. The follow-up period ranged from two months to two years in the trials. The odds ratio (OR) 0.38 [0.19, 0.77] and the risk ratio (RR) 0.52 [0.32, 0.85] indicated that both the odds as well as the relative risk of experiencing dental trauma were lower in the group with negligible impact compared to the group with noticeable impact. Conclusion and further implications: The findings show that dental trauma significantly affects orthodontic parameters, with lower risk and likelihood of suffering dental trauma in the group with negligible impact than in the group with noticeable impact. However, given the substantial heterogeneity among the studies, it is advised to exercise caution when extrapolating the findings to all populations. Registration and protocol: Registration in the PROSPERO database was carried out before initiating the investigation [CRD42023407218]. [ABSTRACT FROM AUTHOR]

Coronavirus disease of 2019 (COVID‑19), which has affected almost all medical professions, has had a significant negative influence on dental care. Additionally, non‑urgent dental procedures were stopped during the epidemic in a number of countries. The purpose of this systematic review was to examine the impact of COVID‑19 on individuals who had undergone or are currently having orthodontic treatment in any capacity during/after the pandemic’s occurrence. After a thorough search of the online journals, a total of 634 documents were found, and 416 of the papers were initially chosen. The removal of 362 similar or duplicate publications that followed led to the initial availability of 54 separate papers. The final selection consisted of 23 documents, mostly in vitro investigations, cross‑sectional studies, and comparative evaluations, which satisfied the necessary inclusion and exclusion criteria. COVID‑19 had a significant impact on nearly every sphere of the patients’ lives who were undergoing orthodontic treatment. However, people who are currently availing of various orthodontic treatment modalities did not experience the same issues as the ones faced by patients earlier. Teleorthodontics emerged as a viable option to access treatment during the lockdown period caused due to the pandemic. COVID‑19 also had an overall negative impact on the psyche and morale of orthodontists around the world. [ABSTRACT FROM AUTHOR]

A variety of metals and alloys are employed in the field of orthodontics, of which the construction of wires happens to be predominant. Through this systematic review, our primary goal was to review and assess studies focusing on complications that emerged during or directly after the completion of an orthodontic treatment plan. We then used a meta-analysis to determine how these complications affected the patients who were receiving orthodontic treatment. A total of 634 documents were discovered after a thorough search of online journals, and 416 of the papers were initially selected. In the end, 14 papers, including in vitro experiments, literature reviews, comparative analyses, observational studies, and retrospective studies, were chosen that met the requisite inclusion and exclusion criteria. There were difficulties related to orthodontic treatment in all of the studies listed in our systematic review, but their severity varied greatly. The effects of gingival mucosa and root resorption were two of the most often mentioned periodontal problems in this review. More long-term studies are required to confirm the involvement of an orthodontic component in these issues, but the majority of the complications were assessed to initially arise after the treatment plan had begun and to resolve with time. [ABSTRACT FROM AUTHOR]

With provisional restorations, properties such as flexural strength play a key role in maintaining the abutment teeth in position over the interim period until the final restorations are placed. This study aimed to evaluate and compare the flexural strength of four commonly used provisional resin materials. Ten identical 25 × 2 × 2 mm specimens were made from four different groups of provisional resin material, namely 1: SR Ivocron (Ivoclar Vivadent) cold-polymerized poly-methyl methacrylate (PMMA), 2: S Ivocron (Ivoclar Vivadent) heat-polymerized PMMA, 3: Protemp (3M Germany-ESPE) auto-polymerized bis-acryl composite, and 4: Revotek LC (GC Corp, Tokyo) light-polymerized urethane dimethacrylate resin. The mean values of the flexural strength of each group were calculated and the data were analyzed using one-way ANOVA and Tukey post hoc tests. The mean values (MPa) were as follows: for cold-polymerized PMMA, it was 125.90 MPa; for heat-polymerized PMMA, it was 140.00 MPa, with auto-polymerized bis-acryl composite 133.00 MPa; and for light-polymerized urethane dimethacrylate resin, it was 80.84 MPa. Thus, the highest flexural strength was recorded with heat-polymerized PMMA and the lowest flexural strength with light-polymerized urethane dimethacrylate resin, which was significantly low. The study did not detect a significant difference in the flexural strengths of cold PMMA, hot PMMA, and auto bis-acryl composite. [ABSTRACT FROM AUTHOR]

Technology is rapidly evolving in the modern world, and the accompanying developments due to its influence are shaping each and every aspect of our life, with the field of orthodontics being no exception. This systematic review and meta-analysis aimed to examine such trends in orthodontics and hypothesize which ones would emerge and continue in the near future. After a thorough search of online journals using keywords such as "3D printing," "Aligners," "Artificial intelligence," "Future trends," "Orthodontics," and "Teleorthodontics" across databases of PubMed-MEDLINE, Web of Science, Cochrane, and Scopus, a total of 634 papers were initially recovered. Technological advancements in 3D printing, Computer-aided design and Computer-aided manufacturing (CAD/CAM), biopolymers and Teleorthodontics were the most important categories of development seen across the 17 studies that we selected for our review. All the investigations selected for this systematic review depicted aspects of orthodontics that were influenced by rapid technological changes and could potentially become mainstream in the coming times. However, caution was sought to be observed in the usage/adoption of some of these trends, with social media usage amongst both patients as well as orthodontists being a prime example of this. [ABSTRACT FROM AUTHOR]

The purpose of this meta-analysis was to strengthen the credibility of primary research results by combining open-source scientific material, namely a comparison of craniofacial features (Cfc) between Crouzon’s syndrome (CS) patients and non-CS populations. All articles published up to October 7, 2021, were included in the search of PubMed, Google Scholar, Scopus, Medline, and Web of Science. The PRISMA guidelines were followed to conduct this study. PECO framework was applied in the following ways: Those who have CS are denoted by the letter P, those who have been diagnosed with CS via clinical or genetic means by the letter E, those who do not have CS by the letter C, and those who have a Cfc of CS by the letter O. Independent reviewers collected the data and ranked the publications based on their adherence to the Newcastle-Ottawa Quality Assessment Scale. A total of six case-control studies were reviewed for this meta-analysis. Due to the large variation in cephalometric measures, only those published in at least two previous studies were included. This analysis found that CS patients had a smaller skull and mandible volumes than those without CS.in terms of SNA° (MD = −2.33, p = <0.001, I2 = 83.6%) and ANB° (MD =−1.89, p=<0.005, I2=93.1%)), as well as ANS (MD =−1.87, p=0.001, I2=96.5%)) and SN/PP (MD =−1.99, p=0.036, I2=77.3%)). In comparison to the general population, people with CS tend to have shorter and flatter cranial bases, smaller orbital volumes, and cleft palates. They differ from the general population in having a shorter skull base and more V-shaped maxillary arches. [ABSTRACT FROM AUTHOR]

Background: The loss of a finger/fingers or any body part is the most distressing, psychologically crippling experience for a patient. Physical and mental rehabilitation and social (re) adjustment are required after a patient loses a body part in an accident or to tumor management. The only hope to rehabilitate such patients is to provide them with a cosmetic and functional prosthesis. Case Presentation: Two case reports are presented here, one prosthesis made with acrylic resin and another with Cosmosil silicone. The acrylic finger prosthesis case report presented here details the rehabilitation of three fingers severed in an accident and the silicone finger prosthesis case report details the rehabilitation of the right-hand index finger severed in an accident. Results: This case report review presents the follow-up satisfaction of both the patients regarding cosmetic appearance and longevity of the finger prosthesis. Conclusion: In this case, the authors found the acrylic resin prosthesis to be more satisfied after a year compared to the silicone prosthesis. [ABSTRACT FROM AUTHOR]

To compare the chelation effect on dentin-root microhardness and surface topography between 17% Ethylenediaminetetraacetic acid (EDTA), a commonly used chelating agent, and a potential chelating agent 25% copolymer of acrylic acid and maleic acid (Poly (AA-co-MA). Eleven extracted, well-preserved maxillary incisors were used. After the routine procedure of endodontic instrumentation, the roots were longitudinally split, dividing them into two halves. The samples were randomly divided into three groups of seven each (n=7). Group one was subjected to 17% EDTA. Group two was subjected to 25% Poly (AA-co-MA). Group 3 was used as a control group and treated only with saline. The chelating agents and saline were applied in a standardized method. The microhardness was evaluated using the Vickers Hardness test which was applied in three different spots on every half tooth. The surface topography was evaluated under Scanning Electronic Microscope. Paired t-test and Post Hoc tests with analysis of variance (ANOVA) were used to estimate the impact of the chelating agents on the dentin-root microhardness and to compare the two agents. A significant difference in the microhardness was observed within Group 1 and Group 2 (before/after) (p<0.05), but no significant difference was seen between Groups 1 and 2 (p>0.05). A scanning electron microscope revealed the clear impact of EDTA and Poly (AA-co-MA) in the removal of the smear layer compared with saline. Within the limitations of this study, it is concluded that 25% Poly (AA-co-MA) can be used as a chelating agent. It has an equal effect to 17% Ethylenediaminetetraacetic acid (EDTA) in reducing the dentin-root microhardness. [ABSTRACT FROM AUTHOR]

The paper proposes a surface plasmon resonance (SPR) biosensor utilizing MXene and a Molybdenum Disulfide (MoS2) material layer, placed on the Ag metal-based conventional biosensor to detect disease in human teeth. The SPR biosensor works on the principle of attenuated total reflection. The transverse matrix method was utilized for the reflectivity calculation. The thickness of the Ag layer, MXene, and MoS2 were taken as 45, 0.993, and 0.375 nm, respectively. Single-layer MoS2 and two layers of MXene were taken, and the highest sensitivity of the sensor for the enamel, dentin, and cementum was obtained at 83.219 deg/RIU, 91.460 deg/RIU, and 104.744 deg/RIU. MoS2 was used to enhance the biocompatibility of the analyte with the sensing layer. The aqueous solution had been considered as sensing medium. [ABSTRACT FROM AUTHOR]

Objective: To identify the cephalometric features of three skeletal jaw relations (Class I, II, and III) in the United Arab Emirates (UAE) local population approaching for orthodontic consultations in males and females. Materials and Methods: A retrospective imaging study of pre-treatment orthodontic cephalometric records of male and female patients from a similar ethnic background was retrieved from clinics in the Northern Emirates. A total of fifty-four lateral cephalometric x-ray samples were selected of orthodontic patients aged between 18 to 40 years and were observed for 8 angular and 6 linear. The 18 cephalometric images were subdivided as 9 males and 9 females into each of Class I, II, and III categories. Results: The majority of angular and linear measurements for the three skeletal types had significant differences amongst the males and females. The anterior and posterior cranial base length and lower anterior facial height showed lower values in class III females and the length of the maxilla (ANS-PNS) showed higher value in Class III males. The length of the mandible (Go-Pog), and lower anterior facial height for male was significantly longer than females in Class III. The Interincisal angle (U1-L1) demonstrated a significant difference among the three Classes with the highest value in Class III followed by Class I and then Class II Conclusion: This study provides us a reference or database for Emirate's population characteristics, which aids in achieving more precise, effective, and successful orthodontic treatments. [ABSTRACT FROM AUTHOR]

This systematic review (SR) and meta-analysis (MA) aimed to compare the treatment effects of orthognathic surgery and orthodontic camouflage treatment in adult subjects with Class III malocclusion (C-III-M). Two independent reviewers conducted the literature search comprehensively from 1990 to 8 November 2021. PubMed, Science Direct, Scopus, EBSCOhost and Google Scholar databases were included for literature search. Moreover, a manual search of references from relevant studies was performed. Based on the literature search, a total of six articles were selected for SR and three articles fulfilled the criteria of a MA. Standardized mean difference (SMD) was used to evaluate and compare the treatment effects of orthodontic camouflage treatment and orthognathic surgery in adult C-III-M patients. Test for overall effect from the studies was used to estimate the treatment effect of C-III-M. However, Significant heterogeneity and publication bias was apparent among the selected studies. More research on the treatment effects of orthodontic camouflage treatment and orthognathic surgery in C-III-M is necessary to conclude possible interactions with better specificity. [ABSTRACT FROM AUTHOR]

The mucocele is the most common minor salivary gland associated disease of the oral cavity. It is also considered one of the most common biopsied oral lesions in pediatric patients. In recent years, extensive evidence has been published about the usage of lasers in treating mucoceles in pediatric patients. The aim of the present study was to assess the effectiveness of laser irradiation in the treatment of pediatric mucocele. An electronic search of databases (PubMed, Scopus, Web of Science and Google Scholar) was carried out in order to identify all relevant articles using a combination of the following keywords: "Pediatric", "Oral", "Mucocele", "Dental", "Oral Medicine", "Soft Dental Lasers", "Hard Dental Lasers", and "Lasers," for all case reports, case series, case-control and cohort studies published from 2007 to 2021. After limiting the search results, removing duplicate titles, and eligibility evaluation, 17 papers were enrolled in the study. Out of the total studies included, 10 articles were related to the diode (635 nm, 808 nm, 810 nm, and 980 nm), 5 to CO2 (10,600 nm), 3 to Er, Cr: YSGG (2780 nm), and 1 involving KTP lasers (532 nm). All studies indicated successful clinical results on mucocele excision with better intra- and post-operative indicators. The general characteristics and outcomes were summarized, and the quality of the studies was assessed using CARE guidelines in this systematic review. The reduction or absence of pain and bleeding, hemostasis, reduced operating time, minimal analgesic consumption, and an antibacterial effect were among the advantages of laser irradiation in the included studies. The laser has proven itself to play an effective role in the treatment of oral mucocele in paediatric patients. [ABSTRACT FROM AUTHOR]

Chronic periodontitis and diabetes mellitus share a two-way relationship, the common factor being the inflammatory-mediated pathway, and various cytokines are released during this inflammatory cascade, one of which being matrix metalloproteinase-9. The aim of this study was to identify whether the levels of matrix metalloproteinase-9 are increased due to type-II diabetes mellitus in chronic periodontitis patients. It was an observational, analytical, case-control study. Thirty subjects were recruited in the test group, who were suffering from type-II diabetes mellitus and chronic periodontitis, and 30 subjects in the control group, who were subjects with chronic periodontitis but systemically healthy. Periodontal parameters, including the plaque score, gingival bleeding index, probing pocket depth and clinical attachment level of the subjects, were measured, saliva samples of all of the subjects were collected and salivary matrix metalloproteinase-9 levels were analyzed by an enzyme-linked immunosorbent assay (ELISA) technique. The statistical analysis was performed using SPSS 24. Overall, the matrix metalloproteinase-9 levels of the diabetic patients with chronic periodontitis were increased almost twofold (156.95 ± 29.80 ng/mL) compared to the levels in the controls (74.96 ± 6.32 ng/mL) (p < 0.001). Similarly, the periodontal parameters were far worse in diabetics with chronic periodontitis compared to the controls. The average gingivitis score for the test subjects was 78.45 ± 8.93%), compared to 29.32 ± 12.96% in the controls (p < 0.001). The mean probing pocket depth for the test group was 5.39 ± 0.60 mm, and, for the control group, it was 4.35 ± 0.31 mm (p < 0.001). For the test subjects, the average clinical attachment level was 5.86 ± 0.58 mm, and it was 4.66 ± 0.32 mm for the controls (p < 0.001). It was ascertained that there is a two-fold increase in the levels of salivary matrix metalloproteinase-9 in the test group compared to the control group. In addition, the level of periodontal apparatus destruction was greater in the test group. This proved that type-II diabetes mellitus influences the levels of matrix metalloproteinase-9 in humans and elevates them, causing further periodontal destruction. [ABSTRACT FROM AUTHOR]

This study aims to compare the hardness, sorption and solubility of commercially available tissue conditioner [TC] modified with chitosan [CS] and synthesized chitosan oligosaccharide [COS] in antifungal concentration. COS was synthesized by acid hydrolysis and characterized by FTIR and XRD. Experimental materials were formulated by incorporating each per gram of TC powder with effective antifungal concentration of chitosan 1.02 mg (Group 1: TC-CS) and 0.51 mg COS (Group 2: TC-COS). A commercially available TC was used as control (Group 0: CTC). Shore A hardness test was performed according to ASTM D 2240-05 (2010) standards on samples stored in dry environment, distilled water (DW) and artificial saliva (AS) at 37 °C (n = 5 per group). Percent weight changes (n = 5 per group) after storage in DW and AS was used to record sorption and solubility. One-way Anova with post hoc Tukey's test was applied. FTIR and XRD confirmed low molecular weight and amorphous nature of COS. Experimental groups had higher Shore A hardness values; however, these changes were not significant. Greatest variations in durometer values (p ≤ 0.05) were observed during the first 24 h. Experimental groups had higher (p ≤ 0.05) percentage sorption and solubility. Samples stored in DW had significantly higher (p = 0.019) sorption, whereas material had higher (p = 0.005) solubility in AS. Mean solubility values in both immersion mediums was highest for Group 2, followed by group 1 and group 0. In addition, significant (p ≤ 0.05) increase in solubility upon aging was noted for each material. Experimental tissue conditioner had higher hardness, sorption and solubility. However, these changes are not substantial to interfere with their tissue healing property. Therefore, these materials may be considered and explored further as potential antimicrobial drug delivery agent for denture stomatitis patients. [ABSTRACT FROM AUTHOR]

aimah University, Ras Al Khaimah, United Arab Emirates; 2Al Qassimi Hospital, Ministry of Health, Ras Al Khaimah, United Arab Emirates; 3Department of Preventive Dental Sciences, College of Dentistry, Jazan University, Jazan City, Kingdom of Saudi ArabiaCorrespondence: Mir Faeq Ali QuadriDepartment of Preventive Dental Sciences, College of Dentistry, Jazan University, PO Box: 114, Jazan City, Kingdom of Saudi ArabiaEmail [email protected] Introduction: The current study is the first to present the cephalometric norms in Emirati adults and aimed to investigate the differences in the angular and linear soft tissue cephalometric measures between male and female Emirati adults. Methods: A group of 176 individuals (91 males and 85 females) with normal occlusion, proportional facial profiles were chosen, and lateral cephalograms were obtained. Standard values of 16 soft-tissue measurements were determined. Descriptive statistics were first carried out for each parameter. The Student's t-test was then performed to determine significant differences between male and female measurement means. Significant differences were determined at the 95% probability level. Results: Soft tissue measurements showed that men had a greater soft tissue profile and H-angle than women. A significant difference between the genders was observed for all linear soft tissue measurements except for the lower lip to E-plane, N'-Sn' and Sn'-Stomion/Sn-Me ratio measurements. The lengths and thicknesses of the upper and lower lips independently, protrusion of both upper and lower lips, Sn'-Me' (mm) and N'-Sn'/Sn'-Me' (%) were found to be significantly different (p < 0.001) and so were the upper lip to E-plane (mm) and the soft tissue thickness of the chin measurements (p < 0.05). Except for upper and lower lip protrusion dimensions and the N'-Sn'/Sn'-Me' (%), men presented with greater linear measurements. Conclusion: The differences in soft-tissue cephalometric norms between men and women were established, suggesting that the orthodontist must individualize therapy using local norms as the reference. [ABSTRACT FROM AUTHOR]

Vaccination is critical to control the rate of coronavirus transmission and infectivity. Dental practices are a high-risk area for contracting coronavirus; this fact generates psychological disturbances amongst patients. In this study, we aimed to assess the levels of anxiety of patients while visiting dental practices before and after getting vaccinated. This cross-sectional study was carried out between March and December 2021. An electronic survey was distributed among the vaccinated individuals who visited dental clinics before and after getting vaccinated. The survey consisted of the following four parts: demographic characteristics, questions related to coronavirus, and anxiety scores before and after getting vaccinated. SPSS-25 was used to perform the statistical analysis, where paired t-test was used to compare the anxiety scores, and Mann–Whitney U test to assess the association of gender with anxiety scores. A p-value of ≤0.05 was considered to be statistically significant. A total of 400 vaccinated individuals participated in this study, with a response rate of 88.23%. The majority of the respondents (71.0%) did not test positive for coronavirus. More than half of the participants (54.0%) reported to not be suffering from any coronavirus-related symptoms. About 100 (25.0%) of the individuals stated that dental clinics are an environment in which there is a high risk of contracting coronavirus. In regards to the comparison of the mean MDAS scores of the participants before and after getting vaccinated, a significant difference (p = 0.001) was found. Vaccination has been recommended for all eligible individuals to control the transmission and infectivity of coronavirus. Vaccinations have decreased the dental anxiety of patients while visiting dental clinics. However, the protective measures are still valid and should be followed, regardless of the vaccination status. [ABSTRACT FROM AUTHOR]

Background: Biological and technical hardware complications in implant-retained prostheses are well documented in the literature. The most frequently reported failures are on the immediate or delayed factors after implant placement. Even when the implant has successfully osseointegrated, there is a chance that the prosthesis can fail if the treatment planning and occlusal aspects are not well studied. Management of failed cases is rarely reported. In this case report, the authors present a failed implant prosthesis and how it was managed well with a more permanent solution. Case presentation: A 55-year-old, male retired bank manager, reported with the chief complaint of frequent fracture of the maxillary acrylic hybrid implant prosthesis that was delivered 6 months ago. He wanted a replacement for the fractured upper maxillary acrylic hybrid prosthesis. On clinical evaluation, the upper maxillary implant prosthesis was opposing the natural tooth, an anterior bridge, and two posterior implants in the lower right and left of the first and second molar region. The patient was happy with the lower restorations. Conclusion: The design of the final restoration based on biological, mechanical, technological, and patient factors should be ideally planned during the initial treatment planning stage itself. In case a prosthesis fails the underlying cause should be analyzed and retreatment planning is to be done. [ABSTRACT FROM AUTHOR]