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555 results on '"Brown, Eric W."'

1. Molecular Techniques in Foodborne Disease Surveillance

Author

Allard, Marc W., primary, Binet, Rachel, additional, Brown, Eric W., additional, Cao, Guojie, additional, Deng, Xiaohong, additional, Grim, Christopher, additional, Hammack, Thomas S., additional, Hoffmann, Maria, additional, Miller, Jennifer, additional, Pettengill, James, additional, Tallent, Sandra M., additional, Timme, Ruth, additional, Wang, Hua, additional, Zhang, Guodong, additional, Chen, Kai-Shun, additional, and Stevens, Eric, additional

Published
2024
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3. Unveiling the genomic landscape of Salmonella enterica serotypes Typhimurium, Newport, and Infantis in Latin American surface waters: a comparative analysis

Author

Chen, Zhao, primary, Toro, Magaly, additional, Moreno-Switt, Andrea I., additional, Adell, Aiko D., additional, Delgado-Suárez, Enrique J., additional, Bonelli, Raquel R., additional, Oliveira, Celso J. B., additional, Reyes-Jara, Angélica, additional, Huang, Xinyang, additional, Albee, Brett, additional, Grim, Christopher J., additional, Allard, Marc, additional, Tallent, Sandra M., additional, Brown, Eric W., additional, Bell, Rebecca L., additional, and Meng, Jianghong, additional

Published
2024
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11. Tracing Origins of the Salmonella Bareilly Strain Causing a Food-borne Outbreak in the United States

Author

Hoffmann, Maria, Luo, Yan, Monday, Steven R., Gonzalez-Escalona, Narjol, Ottesen, Andrea R., Muruvanda, Tim, Wang, Charles, Kastanis, George, Keys, Christine, Janies, Daniel, Senturk, Izzet F., Catalyurek, Umit V., Wang, Hua, Hammack, Thomas S., Wolfgang, William J., Schoonmaker-Bopp, Dianna, Chu, Alvina, Myers, Robert, Haendiges, Julie, Evans, Peter S., Meng, Jianghong, Strain, Errol A., Allard, Marc W., and Brown, Eric W.

Published
2016

13. Capitalization Recovery for Text

Author

Brown, Eric W., Coden, Anni R., Goos, Gerhard, editor, Hartmanis, Juris, editor, van Leeuwen, Jan, editor, Coden, Anni R., editor, Brown, Eric W., editor, and Srinivasan, Savitha, editor

Published
2002
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22. Rapid whole-genome sequencing for surveillance of Salmonella enterica serovar Enteritidis

Author

den Bakker, Henk C., Allard, Marc W., Bopp, Dianna, Brown, Eric W., Fontana, John, Iqbal, Zamin, Kinney, Aristea, Limberger, Ronald, Musser, Kimberlee A., Shudt, Matthew, Strain, Errol, Wiedmann, Martin, and Wolfgang, William J.

Subjects
Nucleotide sequencing -- Genetic aspects -- Analysis, Genomics -- Genetic aspects -- Analysis, DNA sequencing -- Genetic aspects -- Analysis, Genomes -- Genetic aspects -- Analysis, Public health -- Analysis, Salmonella -- Analysis, Health
Abstract

For genetically monomorphic bacteria, current typing methods often prove inadequate for outbreak detection, trace back, and identification of transmission routes. Some of these bacteria, such as Salmonella enterica serovar Enteritidis, [...]

Published
2014
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23. IBM Watson for Clinical Decision Support

Author

Winters-Miner, Linda A., primary, Bolding, Pat, additional, Hill, Thomas, additional, Nisbet, Bob, additional, Goldstein, Mitchell, additional, Hilbe, Joseph M., additional, Walton, Nephi, additional, Miner, Gary, additional, Brown, Eric W., additional, and Kohn, Martin S., additional

Published
2015
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24. Genomic evidence of environmental and resident Salmonella Senftenberg and Montevideo contamination in the pistachio supply-chain

Author

Haendiges, Julie, primary, Davidson, Gordon R., additional, Pettengill, James B., additional, Reed, Elizabeth, additional, Ramachandran, Padmini, additional, Blessington, Tyann, additional, Miller, Jesse D., additional, Anderson, Nathan, additional, Myoda, Sam, additional, Brown, Eric W., additional, Zheng, Jie, additional, Tikekar, Rohan, additional, and Hoffmann, Maria, additional

Published
2021
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28. Phylogenetic evidence for extensive horizontal gene transfer of type III secretion system genes among enterobacterial plant pathogens

Author

Naum, Marianna, Brown, Eric W., and Mason-Gamer, Roberta J.

Subjects
Genetic transformation -- Methods, Bacteria, Phytopathogenic -- Genetic aspects, Bacteria, Phytopathogenic -- Research, Plant genetics -- Research, Biological sciences
Abstract

This study uses sequences from four genes, which are involved in the formation of the type III secretion apparatus, to determine the role of horizontal gene transfer in the evolution of virulence genes for the enterobacterial plant pathogens. Sequences of Erwinia, Brenneria, Pectobacterium, Dickeya and Pantoea were compared (a) with one another, (b) with sequences of enterobacterial animal pathogens, and (c) with sequences of plant pathogenic [gamma] and [beta] proteobacteria, to evaluate probable paths of lateral exchange leading to the current distribution of virulence determinants among these micro-organisms. Phylogenies were reconstructed based on hrcC, hrcR, hrcJ and hrcV gene sequences using parsimony and maximum-likelihood algorithms. Virulence gene phylogenies were also compared with several housekeeping gene loci in order to evaluate patterns of lateral versus vertical acquisition. The resulting phylogenies suggest that multiple horizontal gene transfer events have occurred both within and among the enterobacterial plant pathogens and plant pathogenic [gamma] and [beta] proteobacteria, hrcJ sequences are the most similar, exhibiting anywhere from 2 to 50% variation at the nucleotide level, with the highest degree of variation present between plant and animal pathogen sequences, hrcV sequences are conserved among plant and animal pathogens at the N terminus. The C-terminal domain is conserved only among the enterobacterial plant pathogens, as are the hrcC and hrcR sequences. Additionally, hrcJ and hrcV sequence phylogenies suggest that at least some type III secretion system virulence genes from enterobacterial plant pathogens are related more closely to those of the genus Pseudomonas, a conclusion neither supported nor refuted by hrcC or hrcR. DOI 10.1099/mic.0.029892-0

Published
2009

30. A Generalized Potentiostat Adaptor for Multiplexed Electroanalysis

Author

Clark, Rebecca B., primary, Glasscott, Matthew W., additional, Verber, Matthew D., additional, DeMartino, Jenna C., additional, Netchaev, Anton, additional, Ray, Jason D., additional, Brown, Eric W., additional, Alberts, Erik, additional, Fernando, P U Ashvin Iresh, additional, Moores, Lee C., additional, and Dick, Jeffrey E., additional

Published
2021
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31. Attribution of Listeria monocytogenes human infections to food and animal sources in Northern Italy

Author

Filipello, Virginia, Mughini-Gras, Lapo, Gallina, Silvia, Vitale, Nicoletta, Mannelli, Alessandro, Pontello, Mirella, Decastelli, Lucia, Allard, Marc W, Brown, Eric W, Lomonaco, Sara, IRAS OH Epidemiology Microbial Agents, and dIRAS RA-I&I I&I

Subjects
Veterinary medicine, Meat, Swine, Epidemic clones, Virulence, Food Contamination, Biology, medicine.disease_cause, Microbiology, molecular epidemiology, Disease Outbreaks, Foodborne Diseases, 03 medical and health sciences, Dairy Products/microbiology, Listeria monocytogenes, Case fatality rate, medicine, Animals, Listeriosis, Typing, Disease burden, 030304 developmental biology, Listeria monocytogenes, listeriosis, food safety, epidemic clones, source attribution, molecular epidemiology, 0303 health sciences, Meat/microbiology, Molecular epidemiology, Seafood/microbiology, 030306 microbiology, business.industry, Foodborne Diseases/epidemiology, Outbreak, Food safety, food safety, Seafood, Italy, Cattle, Dairy Products, business, Chickens, source attribution, Food Science, Multilocus Sequence Typing
Abstract

Listeriosis is a foodborne illness characterized by a relatively low morbidity, but a large disease burden due to the severity of clinical manifestations and the high case fatality rate. Increased listeriosis notifications have been observed in Europe since the 2000s. However, the reasons for this increase are largely unknown, with the sources of sporadic human listerioris often remaining elusive. Here we inferred the relative contributions of several putative sources of Listeria monocytogenes strains from listerioris patients in Northern Italy (Piedmont and Lombardy regions), using two established source attribution models (i.e. 'Dutch' and 'STRUCTURE') in comparative fashion. We compared the Multi-Locus Sequence Typing and Multi-Virulence-Locus Sequence Typing profiles of strains collected from beef, dairy, fish, game, mixed foods, mixed meat, pork, and poultry. Overall, 634 L. monocytogenes isolates were collected from 2005 to 2016. In total, 40 clonal complexes and 51 virulence types were identified, with 36% of the isolates belonging to possible epidemic clones (i.e. genetically related strains from unrelated outbreaks). Source attribution analysis showed that 50% of human listerioris cases (95% Confidence Interval 44-55%) could be attributed to dairy products, followed by poultry and pork (15% each), and mixed foods (15%). Since the contamination of dairy, poultry and pork products are closely linked to primary production, expanding actions currently limited to ready-to-eat products to the reservoir level may help reducing the risk of cross-contamination at the consumer level.

Published
2020

32. Enhanced Subtyping scheme for Salmonella Enteritidis

Author

Zheng, Jie, Keys, Christine E., Zhao, Shaohua, Meng, Jianghong, and Brown, Eric W.

Subjects
Salmonella enteritidis -- Research, Salmonella enteritidis -- Diseases, Lymphocytes -- Histology, Lymphocytes -- Methods
Abstract

To improve pulsed-field gel electrophoresis-based strain discrimination of 76 Salmonella Enteritidis strains, we evaluated 6 macro-restriction endonucleases, separately and in various combinations. One 3-enzyme subset, Sfil/Pacl/Notl, was highly discriminatory. Five [...]

Published
2007

34. Attribution of Listeria monocytogenes human infections to food and animal sources in Northern Italy

Author

IRAS OH Epidemiology Microbial Agents, dIRAS RA-I&I I&I, Filipello, Virginia, Mughini-Gras, Lapo, Gallina, Silvia, Vitale, Nicoletta, Mannelli, Alessandro, Pontello, Mirella, Decastelli, Lucia, Allard, Marc W, Brown, Eric W, Lomonaco, Sara, IRAS OH Epidemiology Microbial Agents, dIRAS RA-I&I I&I, Filipello, Virginia, Mughini-Gras, Lapo, Gallina, Silvia, Vitale, Nicoletta, Mannelli, Alessandro, Pontello, Mirella, Decastelli, Lucia, Allard, Marc W, Brown, Eric W, and Lomonaco, Sara

Published
2020

37. Survey of Salmonella in raw tree nuts at retail in the United States

Author

Zhang, Guodong, primary, Hu, Lijun, additional, Luo, Yan, additional, Santillana Farakos, Sofia M, additional, Johnson, Rhoma, additional, Scott, Virginia N., additional, Curry, Phillip, additional, Melka, David, additional, Brown, Eric W., additional, Strain, Errol, additional, Bunning, Vincent K., additional, Musser, Steven M., additional, and Hammack, Thomas S., additional

Published
2021
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39. Structure and distribution of the phosphoprotein phosphatase genes, prpA and prpB, among Shigella subgroups

Author

Li, Baoguang, Brown, Eric W., D'Agostino, Christine, and LeClerc, J. Eugene Cebula, Thomas A.

Subjects
Shigella -- Genetic aspects, Phosphatases -- Research, Phosphoproteins -- Research, Genetic research, Biological sciences
Abstract

Phosphoprotein phosphatases encoded by the prpA and prpB genes function in signal transduction pathways for degradation of misfolded proteins in the extracytoplasmic compartments of Escherichia coli. In order to trace the evolution of prp genes and assess their roles in other enteric pathogens, the structure and distribution of these genes among closely related Shigella subgroups were studied. PCR amplification, probe hybridization studies and DNA sequencing were used to determine the prp genotypes of 58 strains from the four Shigella subgroups, Dysenteriae, Boydii, Sonnei and Flexneri. It was found that the prp alleles among Shigella subgroups were extremely susceptible to gene inactivation and that the mutations involved in prp allele inactivation were varied. They included IS insertions, gene replacement by an IS element, a small deletion within the gene or large deletion engulfing the entire gene region, and base substitutions that generated premature termination codons. As a result, of 58 strains studied, only eight (14 %) possessed intact prpA and prpB genes. Of the Shigella strains examined, 76% (44/58) showed at least one of the prp alleles inactivated by one or more IS elements, including IS1, IS4, IS600 and IS629. Phylogenetic analysis revealed that IS elements have been independently acquired in multiple lineages of Shigella, suggesting that loss of functional alleles has been advantageous during Shigella strain evolution.

Published
2005

42. Pandemic Vibrio parahaemolyticus, Maryland, USA, 2012

Author

Haendiges, Julie, Rock, Marvin, Myers, Robert A., Brown, Eric W., Evans, Peter, and Gonzalez-Escalona, Narjol

Subjects
Epidemics -- Health aspects -- Research -- Maryland -- United States, Vibrio -- Research -- Causes of -- Demographic aspects -- Genetic aspects, Databases -- Usage, CD-ROM catalog, Database, CD-ROM database, Health
Abstract

To the Editor: Since 1996, an increasing number of infections caused by Vibrio parahaemolyticus strains belonging to a pandemic clonal complex (CC), CC3, typically O3:K6, have been observed worldwide (1-3); [...]

Published
2014

44. Phylogenetic evidence for horizontal transfer of mutS alleles among naturally occurring Escherichia coli strains

Author

Brown, Eric W., LeClerc, J. Eugene, Li, Baoguang, Payne, William L., and Cebula, Thomas A.

Subjects
Phylogeny -- Research, Genetic polymorphisms -- Analysis, Bacterial genetics -- Research, Escherichia coli -- Genetic aspects, Biological sciences
Abstract

Phylogenetic analysis comparing gene phylogeny to strain phylogeny points out that the mutS-rpoS region of Escherichia coli chromosome is a recombinational hot spot within the chromosome. Data further suggest that the mutS-rpoS region is a 'bastion of polymorphism exhibiting an evolutionary history with mutS alleles'capability for horizontal transfer.

Published
2001

46. A multinational listeriosis outbreak and the importance of sharing genomic data

Author

Pettengill, James B, primary, Markell, Austin, additional, Conrad, Amanda, additional, Carleton, Heather A, additional, Beal, Jennifer, additional, Rand, Hugh, additional, Musser, Steven, additional, Brown, Eric W, additional, Allard, Marc W, additional, Huffman, Jasmine, additional, Harris, Stic, additional, Wise, Matt, additional, and Locas, Annie, additional

Published
2020
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