426 results on '"Cabrales, Pedro"'
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2. Toxic side-effects of diaspirin cross-linked human hemoglobin are attenuated by the apohemoglobin-haptoglobin complex
3. A mathematical model of tissue axial and radial diffusion in the microvasculature for intravascular microscopy and phosphorescence quenching data
4. Hypoxically stored RBC resuscitation in a rat model of traumatic brain injury and severe hemorrhagic shock
5. Intravascularly infused extracellular matrix as a biomaterial for targeting and treating inflamed tissues
6. Changes in oxygen delivery during experimental models of cerebral malaria
7. Polymerized human hemoglobin with low and high oxygen affinity in trauma models
8. Prony Analysis of Left Ventricle Pressure and Volume
9. Apohemoglobin-haptoglobin complex alleviates iron toxicity in mice with β-thalassemia via scavenging of cell-free hemoglobin and heme
10. Implications of microvascular dysfunction and nitric oxide mediated inflammation in severe COVID-19 infection
11. Safety and efficacy of human polymerized hemoglobin on guinea pig resuscitation from hemorrhagic shock
12. Negative pressure increases microvascular perfusion during severe hemorrhagic shock
13. A Review on Microvascular Hemodynamics: The Control of Blood Flow Distribution and Tissue Oxygenation
14. Itaconate modulates tricarboxylic acid and redox metabolism to mitigate reperfusion injury
15. Resuscitation from hemorrhagic shock after traumatic brain injury with polymerized hemoglobin
16. Polymerized albumin restores impaired hemodynamics in endotoxemia and polymicrobial sepsis
17. CX3CL1-Fc treatment prevents atherosclerosis in Ldlr KO mice
18. Quantitative analysis of spatial irregularities in RBCs flows
19. High-molecular-weight linear polymers improve microvascular perfusion after extracorporeal circulation.
20. Navigating the “No Man's Land” of TKI-Failed EGFR-Mutated Non–Small Cell Lung Cancer (NSCLC): A Review
21. RRx-001 protects normal tissues but not tumors via Nrf2 induction and Bcl-2 inhibition
22. Knockdown of ANT2 reduces adipocyte hypoxia and improves insulin resistance in obesity
23. Enzyme promiscuity drives branched-chain fatty acid synthesis in adipose tissues
24. Polymerized human hemoglobin facilitated modulation of tumor oxygenation is dependent on tumor oxygenation status and oxygen affinity of the hemoglobin-based oxygen carrier
25. The Molecular Size of Bioengineered Oxygen Carriers Determines Tissue Oxygenation in a Hypercholesterolemia Guinea Pig Model of Hemorrhagic Shock and Resuscitation.
26. Inflammatory response to implantation of transparent nanocrystalline yttria-stabilized zirconia using a dorsal window chamber model
27. Cardiac-specific knockout and pharmacological inhibition of Endothelin receptor type B lead to cardiac resistance to extreme hypoxia
28. Poly(ethylene glycol) hydrogels with cell cleavable groups for autonomous cell delivery
29. Data Management 101 for drug developers: A peek behind the curtain.
30. GBT021601 improves red blood cell health and the pathophysiology of sickle cell disease in a murine model.
31. Safety and activity of RRx-001 in patients with advanced cancer: a first-in-human, open-label, dose-escalation phase 1 study
32. RRx-001 protects against cisplatin-induced toxicities
33. Endothelin receptor B, a candidate gene from human studies at high altitude, improves cardiac tolerance to hypoxia in genetically engineered heterozygote mice
34. Topically Applied NO‐Releasing Nanoparticles Can Increase Intracorporal Pressure and Elicit Spontaneous Erections in a Rat Model of Radical Prostatectomy
35. The Double-Edged Sword of Erythrocytes in Health and Disease via Their Adhesiveness.
36. RRx-001: a chimeric triple action NLRP3 inhibitor, Nrf2 inducer, and nitric oxide superagonist.
37. A Review of RRx-001: A Late-Stage Multi-Indication Inhibitor of NLRP3 Activation and Chronic Inflammation.
38. Targeting tumor hypoxia with the epigenetic anticancer agent, RRx-001: a superagonist of nitric oxide generation
39. A look inside the mechanistic black box: Are red blood cells the critical effectors of RRx-001 cytotoxicity?
40. Oxygen delivery during extreme anemia with ultra-pure earthworm hemoglobin
41. Phase 1 pilot study of RRx-001 + nivolumab in patients with advanced metastatic cancer (PRIMETIME).
42. Simulation of NO and O2 transport facilitated by polymerized hemoglobin solutions in an arteriole that takes into account wall shear stress-induced NO production
43. Exogenous intravascular nitric oxide enhances ventricular function after hemodilution with plasma expander
44. Nitric Oxide Protection Against Murine Cerebral Malaria Is Associated With Improved Cerebral Microcirculatory Physiology
45. TGF-β: the apex predator of immune checkpoints.
46. Effects of plasma viscosity modulation on cardiac function during moderate hemodilution
47. Exogenous nitric oxide prevents cardiovascular collapse during hemorrhagic shock
48. Increases in core temperature counterbalance effects of haemoconcentration on blood viscosity during prolonged exercise in the heat
49. Synthesis, biophysical properties and pharmacokinetics of ultrahigh molecular weight tense and relaxed state polymerized bovine hemoglobins
50. Low Oxygen-Affinity Hemoglobin Solution Increases Oxygenation of Partially Ischemic Tissue During Acute Anemia
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