272 results on '"Cheng, Seng"'
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2. Glucosylceramide synthase inhibition reduces ganglioside GM3 accumulation, alleviates amyloid neuropathology, and stabilizes remote contextual memory in a mouse model of Alzheimer’s disease
3. Molecular characterization of 'OsCURT1A' from upland rice in response to osmotic stress
4. Molecular characterisation of nerol dehydrogenase gene (PmNeDH) from Persicaria minor in response to stress-related phytohormones
5. Relicensing Practices of Taxi Drivers and Crane Operators Aged 70 Years and above in Singapore
6. Fetal gene therapy for neurodegenerative disease of infants
7. 'Benign' temporal lobe epilepsy with hippocampal sclerosis: A forgotten entity?
8. Gene Transfer of Human Acid Sphingomyelinase Corrects Neuropathology and Motor Deficits in a Mouse Model of Niemann-Pick Type A Disease
9. Glucosylceramide synthase inhibition alleviates aberrations in synucleinopathy models
10. Microarray dataset of transgenic rice overexpressing Abp57
11. Intravitreous injection of AAV2-sFLT01 in patients with advanced neovascular age-related macular degeneration: a phase 1, open-label trial
12. Priapism in a Fabry disease mouse model is associated with upregulated penile nNOS and eNOS expression
13. A Novel Cationic Lipid Greatly Enhances Plasmid DNA Delivery and Expression in Mouse Lung
14. Agarwood Induction: Current Developments and Future Perspectives
15. α-Galactosidase A Knockout Mice: Progressive Organ Pathology Resembles the Type 2 Later-Onset Phenotype of Fabry Disease
16. Glycosphingolipids are modulators of disease pathogenesis in amyotrophic lateral sclerosis
17. The safety profile of a cationic lipid-mediated cystic fibrosis gene transfer agent following repeated monthly aerosol administration to sheep
18. cDNA cloning and expression analysis of the chalcone synthase gene (CHS) from 'polygonum minus
19. Metabolic signatures of amyotrophic lateral sclerosis reveal insights into disease pathogenesis
20. Augmenting CNS glucocerebrosidase activity as a therapeutic strategy for parkinsonism and other Gaucher-related synucleinopathies
21. Tetrahydrobiopterin deficiency in the pathogenesis of Fabry disease
22. Efficacy of Enzyme and Substrate Reduction Therapy with a Novel Antagonist of Glucosylceramide Synthase for Fabry Disease
23. IGF-1 delivery to CNS attenuates motor neuron cell death but does not improve motor function in type III SMA mice
24. CNS expression of glucocerebrosidase corrects α-synuclein pathology and memory in a mouse model of Gaucher-related synucleinopathy
25. Secreted Gaussia luciferase as a sensitive reporter gene for in vivo and ex vivo studies of airway gene transfer
26. Prospects for the gene therapy of spinal muscular atrophy
27. Relationship between neuropathology and disease progression in the SOD1 G93A ALS mouse
28. Inhibiting TGF-β Activity Improves Respiratory Function in mdx Mice
29. Combination Brain and Systemic Injections of AAV Provide Maximal Functional and Survival Benefits in the Niemann-Pick Mouse
30. Effective Gene Therapy in an Authentic Model of Tay-Sachs-Related Diseases
31. The use of carboxymethylcellulose gel to increase non-viral gene transfer in mouse airways
32. Gaucher-related synucleinopathies: The examination of sporadic neurodegeneration from a rare (disease) angle
33. The role of doxorubicin in non-viral gene transfer in the lung
34. Intracerebroventricular infusion of acid sphingomyelinase corrects CNS manifestations in a mouse model of Niemann–Pick A disease
35. Rapid identification of novel functional promoters for gene therapy
36. Targeting nuclear RNA for in vivo correction of myotonic dystrophy
37. In vivo imaging of gene transfer to the respiratory tract
38. Inhibition of osteoclastogenesis by prolyl hydroxylase inhibitor dimethyloxallyl glycine
39. Improved management of lysosomal glucosylceramide levels in a mouse model of type 1 Gaucher disease using enzyme and substrate reduction therapy
40. CNS-targeted gene therapy improves survival and motor function in a mouse model of spinal muscular atrophy
41. Reversibility of neuropathology in Tay-Sachs-related diseases
42. AAV‐mediated expression of galactose‐1‐phosphate uridyltransferase corrects defects of galactose metabolism in classic galactosemia patient fibroblasts.
43. A randomised, double-blind, placebo-controlled phase IIB clinical trial of repeated application of gene therapy in patients with cystic fibrosis
44. Intraparenchymal injections of acid sphingomyelinase results in regional correction of lysosomal storage pathology in the Niemann–Pick A mouse
45. Gene transfer of human acid sphingomyelinase corrects neuropathology and motor deficits in a mouse model of Niemann--Pick type A disease
46. Expression of constitutively stable hybrid hypoxia-inducible factor-1[alpha] protects cultured rat cardiomyocytes against simulated ischemia-reperfusion injury
47. Expression of angiopoietins in renal epithelial and clear cell carcinoma cells: regulation by hypoxia and participation in angiogenesis
48. Assessment of the nuclear pore dilating agent trans-cyclohexane-1,2-diol in differentiated airway epithelium
49. Marked differences in neurochemistry and aggregates despite similar behavioural and neuropathological features of Huntington disease in the full-length BACHD and YAC128 mice
50. Adeno-associated virus-mediated expression of β-hexosaminidase prevents neuronal loss in the Sandhoff mouse brain
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