169 results on '"Cuconati, Andrea"'
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2. Control of Hepatitis B Virus with Imdusiran, a Small Interfering RNA Therapeutic.
3. Discovery of C-Linked Nucleoside Analogues with Antiviral Activity against SARS-CoV-2
4. Preclinical Antiviral and Safety Profiling of the HBV RNA Destabilizer AB-161
5. Genetic Recombination of Poliovirus in a Cell-Free System
6. Pregenomic RNA Launch Hepatitis B Virus Replication System Facilitates the Mechanistic Study of Antiviral Agents and Drug-Resistant Variants on Covalently Closed Circular DNA Synthesis
7. An interferon-beta promoter reporter assay for high throughput identification of compounds against multiple RNA viruses
8. Interferon induction of IFITM proteins promotes infection by human coronavirus OC43
9. Microtiter-Format Assays for HBV Antigen Quantitation in Nonclinical Applications
10. Small molecule inhibitors of ER α-glucosidases are active against multiple hemorrhagic fever viruses
11. Preclinical characterization of AB-506, an inhibitor of HBV replication targeting the viral core protein
12. Host Poly(A) Polymerases PAPD5 and PAPD7 Provide Two Layers of Protection That Ensure the Integrity and Stability of Hepatitis B Virus RNA
13. Chronic hepatitis B: What should be the goal for new therapies?
14. Hepatitis B virus e antigen production is dependent upon covalently closed circular (ccc) DNA in HepAD38 cell cultures and may serve as a cccDNA surrogate in antiviral screening assays
15. Viral homologs of BCL-2: role of apoptosis in the regulation of virus infection
16. A Tetrazolo-pyrimidine Induces Intracellular Redistribution of Hepatitis B Surface Antigen, Resulting in Reduced Secretion: 22
17. A Novel and Selective Inhibitor of Hepatitis B Virus Surface Antigen Secretion: 22
18. Novel Small Molecule Inhibitors of Hepatitis B Virus Surface Antigen Secretion: 26
19. FRI-184-Function and drug combination studies in cell culture models for AB-729, a subcutaneously administered siRNA investigational agent for chronic hepatitis B infection
20. ARB-1740, a RNA Interference Therapeutic for Chronic Hepatitis B Infection
21. Novel substituted aminothiazoles as potent and selective anti-hepatocellular carcinoma agents
22. The antiviral compound 5-(3,4-dichlorophenyl) methylhydantoin inhibits the post-synthetic cleavages and the assembly of poliovirus in a cell-free system
23. Preclinical Profile of AB-423, an Inhibitor of Hepatitis B Virus Pregenomic RNA Encapsidation
24. HBV core protein allosteric modulators differentially alter cccDNA biosynthesis from de novo infection and intracellular amplification pathways
25. A Novel Benzodiazepine Compound Inhibits Yellow Fever Virus Infection by Specifically Targeting NS4B Protein
26. DNA damage response and MCL-1 destruction initiate apoptosis in adenovirus-infected cells
27. ARB-1740, a RNA Interference Therapeutic for Chronic Hepatitis B Infection.
28. Design and synthesis of N-alkyldeoxynojirimycin derivatives with improved metabolic stability as inhibitors of BVDV and Tacaribe virus
29. N-Alkyldeoxynojirimycin derivatives with novel terminal tertiary amide substitution for treatment of bovine viral diarrhea virus (BVDV), Dengue, and Tacaribe virus infections
30. Establishment of an inducible HBV stable cell line that expresses cccDNA-dependent epitope-tagged HBeAg for screening of cccDNA modulators
31. Spinoculation Enhances HBV Infection in NTCP-Reconstituted Hepatocytes
32. Inhibition of Endoplasmic Reticulum-Resident Glucosidases Impairs Severe Acute Respiratory Syndrome Coronavirus and Human Coronavirus NL63 Spike Protein-Mediated Entry by Altering the Glycan Processing of Angiotensin I-Converting Enzyme 2
33. Cell-free synthesis of poliovirus : 14 S subunits are the key intermediates in the encapsidation of poliovirus RNA
34. A study of poliovirus assembly in a cell-free system
35. Inhibition of Hepatitis B Virus Replication by the Host Zinc Finger Antiviral Protein
36. Sulfamoylbenzamide Derivatives Inhibit the Assembly of Hepatitis B Virus Nucleocapsids
37. Suppression of AKT Anti-Apoptotic Signaling by a Novel Drug Candidate Results in Growth Arrest and Apoptosis of Hepatocellular Carcinoma Cells
38. RO 90-7501 Enhances TLR3 and RLR Agonist Induced Antiviral Response
39. Identification of Disubstituted Sulfonamide Compounds as Specific Inhibitors of Hepatitis B Virus Covalently Closed Circular DNA Formation
40. Design, Synthesis, and Biological Evaluation of N-Alkylated Deoxynojirimycin (DNJ) Derivatives for the Treatment of Dengue Virus Infection
41. Abstract C68: Suppression of AKT/mTOR antiapoptotic signaling by a novel drug candidate results in growth arrest and apoptosis of hepatocellular carcinoma-derived cell lines.
42. Design, Synthesis, and Biological Evaluation of Triazolo-pyrimidine Derivatives as Novel Inhibitors of Hepatitis B Virus Surface Antigen (HBsAg) Secretion
43. Alkylated Porphyrins Have Broad Antiviral Activity against Hepadnaviruses, Flaviviruses, Filoviruses, and Arenaviruses
44. Indoleamine 2,3-Dioxygenase Mediates the Antiviral Effect of Gamma Interferon against Hepatitis B Virus in Human Hepatocyte-Derived Cells
45. A Novel High-Throughput Screening Assay to Identify Inhibitors of HIV-1 gp120 Protein Interaction with DC-SIGN
46. Synthesis and Biological Evaluation of Triazolo-pyrimidine Derivatives as Novel Inhibitors of Hepatitis B Virus Surface Antigen (HBsAg) Secretion
47. Activation of Pattern Recognition Receptor-Mediated Innate Immunity Inhibits the Replication of Hepatitis B Virus in Human Hepatocyte-Derived Cells
48. A Substituted Tetrahydro-Tetrazolo-Pyrimidine Is a Specific and Novel Inhibitor of Hepatitis B Virus Surface Antigen Secretion
49. Characterization of the Intracellular Deproteinized Relaxed Circular DNA of Hepatitis B Virus: an Intermediate of Covalently Closed Circular DNA Formation
50. Regulation of Hepatitis B Virus Replication by the Phosphatidylinositol 3-Kinase-Akt Signal Transduction Pathway
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