21 results on '"Fantozzi, Pamela"'
Search Results
2. Acute Tolerability of Methylphenidate in Treatment-Naïve Children with ADHD: An Analysis of Naturalistically Collected Data from Clinical Practice
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Masi, Gabriele, Pfanner, Chiara, Liboni, Francesca, Lenzi, Francesca, Villafranca, Arianna, D’Acunto, Giulia, Fantozzi, Pamela, Falcone, Francesca, Simonelli, Valerio, Muratori, Pietro, Levantini, Valentina, Favole, Irene, Amianto, Federico, Davico, Chiara, and Vitiello, Benedetto
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- 2022
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3. SOCIAL SKILLS INTERVENTIONS FOR ADOLESCENTS WITH LEVEL 1 AUTISM SPECTRUM DISORDER: A SYSTEMATIC REVIEW WITH META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS.
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Narzisi, Antonio, Sesso, Gianluca, Fabbri-Destro, Maddalena, Berloffa, Stefano, Fantozzi, Pamela, Muccio, Rosy, Bruzzi, Gianina, Scatigna, Stefano, Valente, Elena, Viglione, Valentina, Milone, Annarita, Cortese, Samuele, and Masi, Gabriele
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SOCIAL skills education ,AUTISM spectrum disorders ,RANDOMIZED controlled trials ,SOCIAL skills ,INVESTIGATIONAL therapies - Abstract
Objective: Evidence on the efficacy of social skills training for adolescents with Level 1 Autism Spectrum Disorder (ASD) is unclear. Method: We searched Pubmed, Scopus, and Web of Science until July 27th, 2023, for randomized controlled trials (RCTs) of social skills training for pre-adolescents and adolescents (aged 9-18) with Level 1 ASD. We then pooled data on efficacy from individual RCTs by conducting multivariate mixed-effects meta-analyses in R. We estimated possible bias in the retained RCTs using the RoB2 tool. Results: We retained 36 RCTs (encompassing 2796 participants), including 18 RCTs comparing an experimental treatment to a waiting list, and 18 RCTs comparing it to standard care/control treatment. Meta-analyses showed that experimental treatments were significantly more efficacious than waiting list or standard care/ control treatments in improving social skills (SMD = 0.3745; 95%CI = [0.2396; 0.5093]), as well as reducing behavioral symptoms (0.3154;0.1783, 0.4525) and anxious/depressive symptoms (0.2780; 0.0432, 0.5128). However, for some outcomes there was significant heterogeneity across studies and evidence of publication bias. Subgroup analyses and meta-regressions did not identify any specific clinical or demographic factors as significant predictors of outcome. The most common risk of bias across studies was related to deviations from intended interventions and measurement of the outcomes. Conclusions: At the group level, social skills training for adolescents with Level 1 ASD is efficacious, with small-to-moderate effect size. Future research should focus on personalized medicine approaches, aimed at tailoring interventions to specific characteristics of adolescents with Level 1 ASD. [ABSTRACT FROM AUTHOR]
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- 2024
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4. Emotional Dysregulation and Sleep Problems: A Transdiagnostic Approach in Youth.
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Sesso, Gianluca, Guccione, Fulvio, Pisano, Simone, Valente, Elena, Narzisi, Antonio, Berloffa, Stefano, Fantozzi, Pamela, Viglione, Valentina, Milone, Annarita, and Masi, Gabriele
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SLEEP quality ,PATHOLOGICAL psychology ,INTERNALIZING behavior ,EMOTION regulation ,COGNITIVE ability ,SLEEP ,SLEEP interruptions - Abstract
Background: Sleep is a complex phenomenon that affects several aspects of life, including cognitive functioning, emotional regulation, and overall well-being. Sleep disturbances, especially during adolescence, can negatively impact emotional regulation, making it a critical factor in targeting psychopathology. Methods: This study explores the interplay between emotional dysregulation (ED) and sleep patterns in a sample of 90 adolescent patients by means of self- and parent-rated clinical measures. Results: Our findings reveal a bidirectional relationship between ED and sleep problems. Adolescents with higher affective instability experience poorer sleep quality, while those with worse sleep quality exhibit higher internalizing problems. Additionally, emotional reactivity is associated with disrupted circadian rhythms. Conclusions: These results emphasize the significance of addressing sleep problems in the context of psychopathology treatment, potentially leading to improved outcomes. Further research is needed to determine the most effective treatment strategies, including nonpharmacological and pharmacological interventions. Understanding the intricate relationship between sleep problems and emotion regulation offers insights for more targeted and effective treatment approaches for youths struggling with ED. [ABSTRACT FROM AUTHOR]
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- 2024
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5. Emotional dysregulation and callous unemotional traits as possible predictors of short-term response to methylphenidate monotherapy in drug-naïve youth with ADHD
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Masi, Gabriele, Fantozzi, Pamela, Muratori, Pietro, Bertolucci, Giulia, Tacchi, Annalisa, Villafranca, Arianna, Pfanner, Chiara, and Cortese, Samuele
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- 2020
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6. Autistic traits impact on olfactory processing in adolescent girls with Anorexia Nervosa restricting type
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Tonacci, Alessandro, Calderoni, Sara, Billeci, Lucia, Maestro, Sandra, Fantozzi, Pamela, Ciuccoli, Federica, Morales, Maria Aurora, Narzisi, Antonio, and Muratori, Filippo
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- 2019
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7. Hikikomori (Severe Social Withdrawal) in Italian Adolescents: Clinical Features and Follow-Up.
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Tolomei, Greta, Masi, Gabriele, Milone, Annarita, Fantozzi, Pamela, Viglione, Valentina, Narzisi, Antonio, and Berloffa, Stefano
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EVALUATION of medical care ,SEVERITY of illness index ,SOCIAL isolation ,QUESTIONNAIRES ,RESEARCH funding ,INTERNET addiction ,ADOLESCENCE - Abstract
Severe social withdrawal, including staying alone in one's bedroom, non-attendance at school or work, and minimal or absent social contacts, sometimes only through electronic devices, can be found in several psychiatric disorders, or in a 'primary' form, firstly defined in Japan as 'Hikikomori'. The distinction between primary and secondary forms is questionable, as it prevalently depends on the quality of psychiatric assessment. To date, few studies specifically explored Hikikomori in an adolescent population outside Japan. The aim of the present study is to describe clinical features of a consecutive group of 80 referred youth (13 to 18 years, 57 males) with social isolation, of which 40 were followed up on for 4–6 months, to characterize clinical features and outcome. All the participants presented psychiatric comorbid disorders, prevalently anxiety disorders, mood disorders, and autism spectrum disorder. Suicidality (ideation and behavior) was reported in 32.5% of the participants, and 20% of the participants attempted suicide. More than half of the participants exceeded the cut-off of the Internet Addiction Test, and 42.4% met the criteria for the Internet Gaming Disorder. At the follow-up appointment, an improvement of social withdrawal was reported in 75% of the sample; 67.5% of the participants significantly improved according to the CGI-improvement scale; and 55% of the participants had an improvement of functioning according to the C-GAS. Our findings suggest that Hikikomori is a transnosographic entity, with high rates of suicidality and Internet addiction, and that can it improve when it is timely diagnosed and treated. [ABSTRACT FROM AUTHOR]
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- 2023
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8. Persistent Non-Suicidal Self-Injury and Suicidality in Referred Adolescents: A Longitudinal Study Exploring the Role of Cyclothymic Temperament.
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Masi, Gabriele, Pisano, Simone, Sesso, Gianluca, Mazzullo, Cristina, Berloffa, Stefano, Fantozzi, Pamela, Narzisi, Antonio, Placini, Francesca, Valente, Elena, Viglione, Valentina, and Milone, Annarita
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SELF-injurious behavior ,SUICIDAL ideation ,SUICIDAL behavior ,ATTEMPTED suicide ,TEMPERAMENT - Abstract
Non-suicidal self-injury (NSSI) is deliberate harm to the body surface without suicidal intent, though it may be a predictor of suicide attempts. Our aim was to test the hypothesis that persisting and recovering NSSI may have a different longitudinal risk for suicidal ideation and behavior and that the intensity of Cyclothymic Hypersensitive Temperament (CHT) may increase this risk. Fifty-five patients (mean age 14.64 ± 1.77 years) referred for mood disorders according to the DSM-5 were consecutively recruited and followed-up for a mean of 19.79 ± 11.67 months and grouped according to the presence/absence of NSSI at baseline and follow-up into three groups: without NSSI (non-NSSI; n = 22), with NSSI recovered at follow-up (past-NSSI; n = 19), and with persistent NSSI at follow-up (pers-NSSI; n = 14). At follow-up, both NSSI groups were more severely impaired and failed to improve internalizing problems and dysregulation symptoms. Both NSSI groups reported higher scores in suicidal ideation compared to non-NSSI, but only pers-NSSI presented higher scores in suicidal behavior. CHT was higher in pers-NSSI, followed by past-NSSI and then by non-NSSI. Our data support a continuity between NSSI and suicidality, and they suggest the prognostic validity of persistent NSSI, associated with highest CHT scores. [ABSTRACT FROM AUTHOR]
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- 2023
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9. Neurodevelopmental Disorders, Schizophrenia Spectrum Disorders and Catatonia: The "Iron Triangle" Rediscovered in a Case Report.
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Fantozzi, Pamela, Del Grande, Claudia, Berloffa, Stefano, Tolomei, Greta, Salluce, Carmen, Narzisi, Antonio, Salarpi, Gianluca, Capovani, Barbara, and Masi, Gabriele
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THERAPEUTIC use of lithium ,DIAGNOSIS of schizophrenia ,DIAGNOSIS of autism ,SUBSTANCE abuse ,ELECTROCONVULSIVE therapy ,CATATONIA ,CHILD psychopathology ,MENTAL depression ,CLASSIFICATION of mental disorders ,EMOTION regulation ,ANTIPSYCHOTIC agents ,VALPROIC acid ,GABAPENTIN ,TRANQUILIZING drugs ,SYMPTOMS ,ADOLESCENCE - Abstract
Catatonia is a complex neuropsychiatric syndrome, occurring in the context of different psychiatric and neurodevelopmental disorders, in neurological and medical disorders, and after substance abuse or withdrawal. The relationship between Autism Spectrum Disorder (ASD), Schizophrenia Spectrum Disorders (SSDs) and catatonia has been previously discussed, with the three disorders interpreted as different manifestations of the same underlying brain disorder (the "Iron Triangle"). We discuss in this paper the diagnostic, clinical and therapeutic implications of this complex relationship in an adolescent with ASD, who presented an acute psychotic onset with catatonia, associated with mixed mood symptoms. Second-generation antipsychotics were used to manage psychotic, behavioral and affective symptoms, with worsening of the catatonic symptoms. In this clinical condition, antipsychotics may be useful at the lowest dosages, with increases only in the acute phases, especially when benzodiazepines are ineffective. Mood stabilizers with higher GABAergic effects (such as Valproate and Gabapentin) and Lithium salts may be more useful and well tolerated, given the frequent association of depressive and manic symptoms with mixed features. [ABSTRACT FROM AUTHOR]
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- 2023
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10. Callous–Unemotional Traits and Intelligence in Children with Externalizing Behavioral Problems.
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Fantozzi, Pamela, Muratori, Pietro, Levantini, Valentina, Mammarella, Irene, Masi, Gabriele, Milone, Annarita, Petrucci, Alessia, Ricci, Federica, Tacchi, Annalisa, Cristofani, Chiara, and Valente, Elena
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PERSONALITY ,CONFIDENCE intervals ,REGRESSION analysis ,ATTENTION-deficit hyperactivity disorder ,INTELLECT ,DESCRIPTIVE statistics ,QUESTIONNAIRES ,RESEARCH funding ,CHILDREN - Abstract
Research on the association between callous–unemotional (CU) traits and intelligence yielded contradictory results. Moreover, several previous studies focused on global intelligence scores or verbal vs. nonverbal/performance abilities usually evaluated with short/abbreviated instruments. The current study builds on these previous works and explores the link between CU traits and intelligence using the full version of the Wechsler Intelligence Scale for Children—4th Edition (WISC-IV), which provides four different verbal and nonverbal abilities scores. This guarantees a more detailed evaluation of children's intelligence and its relation to CU traits. The sample included children (N = 149; age 6–14 years old) with severe behavioral problems. Clinicians administered the WISC-IV, and parents completed questionnaires evaluating the child's externalizing problems and CU traits. Findings showed that CU traits were associated with lower verbal comprehension scores after also controlling for gender, age, externalizing problems, and the other WISC-IV indexes. In addition, CU traits and externalizing problems did not interact in predicting the WISC-IV indexes, and there were no significant differences in the WISC-IV indexes between children with CU traits and high vs. low externalizing problems. The current study suggests the relevance of assessing and addressing verbal abilities in children with behavioral problems and CU traits. [ABSTRACT FROM AUTHOR]
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- 2022
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11. Early Sensory Profile in Autism Spectrum Disorders Predicts Emotional and Behavioral Issues.
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Fabbri-Destro, Maddalena, Maugeri, Federica, Ianni, Carolina, Corsini, Sofia, Di Stefano, Erica, Scatigna, Stefano, Crifaci, Giulia, Bruzzi, Gianina, Berloffa, Stefano, Fantozzi, Pamela, Prato, Adriana, Muccio, Rosy, Valente, Elena, Pelagatti, Susanna, Pecchini, Edoardo, Zulli, Filippo, Rizzo, Renata, Milone, Annarita, Viglione, Valentina, and Barone, Rita
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AUTISM spectrum disorders ,CHILD Behavior Checklist ,EMOTIONAL problems of children ,SOCIAL impact ,SOCIAL participation - Abstract
Background: Abnormal sensory reactivity is considered one of the diagnostic criteria for autism spectrum disorders (ASD) and has been associated with autism severity, poorer functional outcomes, and behavioral difficulties across the lifespan. Its early characterization could provide valuable insights into the processes favoring the instantiation of maladaptive behaviors. Objectives: The present study has two aims: (1) to describe the sensory profile of preschool children with ASD compared with an age-matched population of children with a diagnosis of language disorder (DLD) and typically developing (TD) control peers; (2) to explore within each group whether the sensory alterations play a predictive role in the instantiation of emotional and behavioral issues. Methods: The parents of 42 ASD, 18 DLD, and 56 TD filled out the Sensory Processing Measure—Preschool (SPM-P). To gather information on competencies, behaviors, and emotional problems of children, the Child Behavior Checklist 1½-5 (CBCL 1½-5) was also administered. Results: On the SPM-P, ASD and DLD samples generally had scores more compromised than control peers. The contrast between ASD and DLD was reflected in a higher (and highly significant) impairment on the social participation and hearing subscales, suggesting a greater sensitivity and a possible specificity of these scores for ASD. More importantly, linear regression analyses revealed a strong and predictive association for ASD children with SPM total scores explaining more than 50% of the variance of the CBCL 1½-5 total scores (p < 0.001). Conclusions: Our findings reinforce the need to detect the abnormal sensory profiles of ASD already at an early stage and during clinical evaluations. Due to the impact on the emotional and behavioral manifestations, such a procedure has significant clinical and social implications, potentially guiding the development of new interventions relying on multisensory strategies. [ABSTRACT FROM AUTHOR]
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- 2022
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12. Sensory Profiles in School-Aged Children with Autism Spectrum Disorder: A Descriptive Study Using the Sensory Processing Measure-2 (SPM-2).
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Narzisi, Antonio, Fabbri-Destro, Maddalena, Crifaci, Giulia, Scatigna, Stefano, Maugeri, Federica, Berloffa, Stefano, Fantozzi, Pamela, Prato, Adriana, Muccio, Rosy, Valente, Elena, Viglione, Valentina, Pecchini, Edoardo, Pelagatti, Susanna, Rizzo, Renata, Milone, Annarita, Barone, Rita, and Masi, Gabriele
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CHILDREN with autism spectrum disorders ,SCHOOL children ,SENSORIMOTOR integration ,AUTISM spectrum disorders ,PSYCHOEDUCATION ,AUTONOMY (Psychology) - Abstract
Background: Sensory reactivity is considered one of the diagnostic criteria for Autism Spectrum Disorders (ASD) and has been associated with poorer functional outcomes, behavioral difficulties, and autism severity across the lifespan. The characterization of the sensory processing in ASD has thus become crucial to identify the sensory and motor features influencing the development of personal autonomy. Objectives: The present study has two aims: (1) to compare the sensory processing between school-aged children with ASD and typically developing peers (TD); (2) to evaluate whether, within the ASD sample, the cognitive level and reported sensory symptoms explain the scores exhibited at the Sensory Processing Measure (SPM-2). Methods: The SPM-2 test was administered to the parents of 105 children with ASD and 70 TD. The ASD group was further subdivided into two groups, namely high and low functioning based on their cognitive level (High Functioning (HF), IQ > 80; Low Functioning (LF), IQ < 80). Results: ASD children exhibited higher scores throughout the SPM-2 total score and its multiple subscales. Within ASD, while HF and LF children did not differ in terms of the SPM-2 total score, a significant difference was found for the hearing, social participation, and balance and motion subscales. Conclusions: Aside from classical knowledge that the ASD population suffers from sensory processing disorders, we revealed that different sensory patterns are associated with high or low cognitive functioning. Beyond its neurobiological interest, such knowledge may be of fundamental importance for individualizing psychoeducational interventions in preschool- and school-aged children and later developmental stages. [ABSTRACT FROM AUTHOR]
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- 2022
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13. Internet Gaming Disorder in Children and Adolescents with Attention Deficit Hyperactivity Disorder.
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Berloffa, Stefano, Salvati, Andrea, D'Acunto, Giulia, Fantozzi, Pamela, Inguaggiato, Emanuela, Lenzi, Francesca, Milone, Annarita, Muratori, Pietro, Pfanner, Chiara, Ricci, Federica, Ruglioni, Laura, Tacchi, Annalisa, Tessa, Chiara, Villafranca, Arianna, and Masi, Gabriele
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STATISTICS ,ANALYSIS of variance ,GAMES ,ATTENTION-deficit hyperactivity disorder ,DESCRIPTIVE statistics ,CHI-squared test ,DISEASE prevalence ,INTERNET addiction ,LOGISTIC regression analysis ,DATA analysis ,CHILDREN ,ADOLESCENCE - Abstract
Although Attention Deficit Hyperactivity Disorder (ADHD) has been related to an increased risk for behavioral addictions, the relationship between ADHD and Internet Gaming Disorder (IGD) is still debated. The aim of this study is to address this topic by exploring the prevalence of IGD in a consecutive sample of ADHD youth, compared to a normal control group, and by assessing selected psychopathological and cognitive features in ADHD patients with and without IGD. One hundred and eight patients with ADHD (mean age 11.7 ± 2.6 years, 96 males) and 147 normal controls (NC) (mean age 13.9 ± 3.0 years, 114 males) were included in the study and received structured measures for IGD. In the ADHD group, 44% of the sample were above the IGD cut-off, compared to 9.5% in the NC group. ADHD patients with IGD presented with greater severity and impairment, more severe ADHD symptomatology, more internalizing symptoms, particularly withdrawal/depression and socialization problems, and more prominence of addiction and evasion dimensions. A binary logistic regression showed that the degree of inattention presented a greater weight in determining IGD. These findings may be helpful for identifying, among ADHD patients, those at higher risk for developing a superimposed IGD. [ABSTRACT FROM AUTHOR]
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- 2022
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14. Treatment with Methylphenidate Improves Affective but Not Cognitive Empathy in Youths with Attention-Deficit/Hyperactivity Disorder.
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Fantozzi, Pamela, Muratori, Pietro, Caponi, Maria Celeste, Levantini, Valentina, Nardoni, Cristina, Pfanner, Chiara, Ricci, Federica, Sesso, Gianluca, Tacchi, Annalisa, Milone, Annarita, and Masi, Gabriele
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METHYLPHENIDATE ,COGNITIVE ability ,ATTENTION-deficit hyperactivity disorder ,EMPATHY ,SYMPTOMS - Abstract
Background: Beside the core symptoms, patients with attention-deficit/hyperactivity disorder (ADHD) frequently show relevant difficulty in developing relationships with peers. Although ADHD symptoms may account for social impairment, deficits in cognitive and/or affective empathy have also been involved. Our aim was to investigate the effect of methylphenidate (MPH) treatment on affective and cognitive empathy. Methods: Sixty-one drug-naïve youths with ADHD (age range 6 to 17 years, mean 10.3 ± 2.8 years, 51 males) naturalistically treated with MPH monotherapy were followed up for 6 months for ADHD symptoms and empathy, measured with the Basic Empathy Scale. Results: After being treated with MPH, the patients showed a significant improvement in affective and cognitive empathy scores. Linear regression models showed that changes in inattention symptoms predicted changes in affective but not in cognitive empathy, while changes in the hyperactivity/impulsivity symptoms did not predict changes in affective or cognitive empathy. Conclusions: Our study provides a further contribution for a better understanding of the possible effects of the MPH on youth’s characteristics. [ABSTRACT FROM AUTHOR]
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- 2021
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15. Effects of melatonin in children with attention-deficit/hyperactivity disorder with sleep disorders after methylphenidate treatment.
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Masi, Gabriele, Fantozzi, Pamela, Villafranca, Arianna, Tacchi, Annalisa, Ricci, Federica, Ruglioni, Laura, Inguaggiato, Emanuela, Pfanner, Chiara, and Cortese, Samuele
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SLEEP disorders , *CHRONOBIOLOGY disorders , *DRUG side effects , *SLEEP hygiene , *BEHAVIOR disorders , *YOUTH with attention-deficit hyperactivity disorder , *LIKERT scale - Abstract
Purpose: Methylphenidate (MPH), the first-line medication in children with attention-deficit/hyperactivity disorder (ADHD), is associated with increased risk of sleep disorders. Melatonin has both hypnotic and chronobiotic properties that influence circadian rhythm sleep disorders. This study explores the effectiveness of melatonin in children with ADHD who developed sleep problems after starting MPH. Patients and methods: This study, based on a clinical database, included 74 children (69 males, mean age 11.6±2.2 years) naturalistically treated with MPH (mean dosage 33.5±13.5 mg/d). The severity of sleep disorder (sleep onset delay) was recorded at baseline and after a follow-up of at least 4 weeks using a seven-point Likert scale according to the Clinical Global Impression Severity score. Effectiveness of melatonin on sleep (mean dosage 1.85±0.84 mg/d) after 4 weeks was assessed using a seven-point Likert scale according to the Clinical Global Impression Improvement (CGI-I) score, and patients who scored 1 (very much improved) or 2 (much improved) were considered responders. Results: Clinical severity of sleep disorders was 3.41±0.70 at the baseline and 2.13±1.05 after the follow-up (P<0.001). According to the CGI-I score, 45 patients (60.8%) responded to the treatment with melatonin. Gender and age (children younger and older than 12 years) did not affect the response to melatonin on sleep. Patients with or without comorbidities did not differ according to sleep response. Specific comorbidities with disruptive behavior disorders (oppositional defiant disorder or conduct disorder), affective (mood and anxiety) disorders and learning disabilities did not affect the efficacy of melatonin on sleep. Treatment was well tolerated, and no side effects related to melatonin were reported. Conclusion: In children with ADHD with sleep problems after receiving MPH treatment, melatonin may be an effective and safe treatment, irrespective of gender, age and comorbidities. [ABSTRACT FROM AUTHOR]
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- 2019
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16. The impact of internalizing symptoms on autistic traits in adolescents with restrictive anorexia nervosa.
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Calderoni, Sara, Fantozzi, Pamela, Balboni, Giulia, Pagni, Veronica, Franzoni, Emilio, Apicella, Fabio, Narzisi, Antonio, Maestro, Sandra, and Muratori, Filippo
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ANOREXIA nervosa , *AUTISM , *EATING disorders , *AUTISM spectrum disorders , *TEENAGERS - Abstract
Background: Although previous studies indicated a positive association between restrictive anorexia-nervosa (AN-R) and autistic traits, the potential interference of psychiatric internalizing comorbidity on this association is not yet fully investigated. Materials and methods: The aim of this study was to explore autistic traits and internalizing psychopathology in adolescents (age range: 11.7-17.2 years) with AN-R. Twenty-five patients referred to two tertiary-care hospitals were compared to a large control group (N=170) with no differences in age and sex. AN-R patients and controls filled out instruments assessing autistic traits (autism spectrum quotient [AQ]), psychopathology (youth self-report [YSR] 11-18), and eating patterns (eating attitude test [EAT]). In order to disentangle the possible mediating role of internalizing symptoms on autistic traits, two separate control groups (called True and False healthy control, both composed of 25 eating-problem-free participants) were derived from the whole control group on the basis of the presence or absence of internalizing problems in the YSR. Results: AN-R patients scored significantly higher on AQ compared to the whole control group and to controls without internalizing problems (True HC), but these differences disappeared when only controls with internalizing problems (False HC) were considered. Conclusion: Autistic traits in AN-R individuals may have been overestimated and may partly be due to comorbid internalizing symptoms in investigated patients. [ABSTRACT FROM AUTHOR]
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- 2015
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17. Selective cognitive empathy deficit in adolescents with restrictive anorexia nervosa.
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Calderoni, Sara, Fantozzi, Pamela, Maestro, Sandra, Brunori, Elena, Narzisi, Antonio, Balboni, Giulia, and Muratori, Filippo
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TEENAGERS , *ANOREXIA nervosa , *BODY image , *EATING disorders , *BULIMIA , *EMPATHY - Abstract
Background: A growing, but conflicting body of literature suggests altered empathic abilities in subjects with anorexia nervosa-restricting type (AN-R). This study aims to characterize the cognitive and affective empathic profiles of adolescents with purely AN-R. Methods: As part of a standardized clinical and research protocol, the Interpersonal Reactivity Index (IRI), a valid and reliable self-reported instrument to measure empathy, was administered to 32 female adolescents with AN-R and in 41 healthy controls (HC) comparisons, matched for age and gender. Correlational analyses were performed to evaluate the links between empathy scores and psychopathological measures. Results: Patients scored significantly lower than HC on cognitive empathy (CE), while they did not differ from controls on affective empathy (AE). The deficit in CE was not related to either disease severity nor was it related to associated psychopathology. Conclusion: These results, albeit preliminary, suggest that a dysfunctional pattern of CE capacity may be a stable trait of AN-R that should be taken into account not only for the clinical management, but also in preventive and therapeutic intervention. [ABSTRACT FROM AUTHOR]
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- 2013
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18. Biological Bases of Empathy and Social Cognition in Patients with Attention-Deficit/Hyperactivity Disorder: A Focus on Treatment with Psychostimulants.
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Fantozzi, Pamela, Sesso, Gianluca, Muratori, Pietro, Milone, Annarita, and Masi, Gabriele
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SOCIAL perception , *ATTENTION-deficit hyperactivity disorder , *EMOTION recognition , *STIMULANTS , *DRUG therapy - Abstract
In recent years, there has been growing interest in investigating the effect of specific pharmacological treatments for ADHD not only on its core symptoms, but also on social skills in youths. This stands especially true for ADHD patients displaying impulsive aggressiveness and antisocial behaviors, being the comorbidity with Disruptive Behavior Disorders, one of the most frequently observed in clinical settings. This systematic review aimed to synthesize research findings on this topic following PRISMA guidelines and to identify gaps in current knowledge, future directions, and treatment implications. Search strategies included the following terms: ADHD; methylphenidate and other ADHD drugs; empathy, theory of mind and emotion recognition. Full-text articles were retrieved and data from individual studies were collected. Thirteen studies were finally included in our systematic review. Ten studies assessing changes in empathy and/or theory of mind in patients with ADHD treated after pharmacological interventions were identified. Similarly, seven partially overlapping studies assessing changes in emotion recognition were retrieved. Despite a great heterogeneity in the methodological characteristics of the included studies, most of them reported an improvement in emphatic and theory of mind abilities in youths with ADHD treated with psychostimulants and nonstimulant drugs, as well as positive but less consistent results about emotion recognition performances. [ABSTRACT FROM AUTHOR]
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- 2021
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19. Could You Give Me the Blue Brick? LEGO ® -Based Therapy as a Social Development Program for Children with Autism Spectrum Disorder: A Systematic Review.
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Narzisi, Antonio, Sesso, Gianluca, Berloffa, Stefano, Fantozzi, Pamela, Muccio, Rosy, Valente, Elena, Viglione, Valentina, Villafranca, Arianna, Milone, Annarita, and Masi, Gabriele
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CHILDREN with autism spectrum disorders ,SOCIAL development ,SOCIAL services ,CHILD development ,SOCIAL skills - Abstract
LEGO
® -based therapy is a social skills development program aimed at children with autism spectrum disorder (ASD). A systematic review of the literature was conducted using PRISMA guidelines. PubMed, Scopus and Web of Science bibliographic databases were searched from their date of inception to August 2020. The review included 19 studies. Studies were classified according to experimental designs (e.g., Randomized Control Trial, Non-Randomized Studies of Interventions and case report and series) and a narrative synthesis of each was provided, along with a critical discussion of the strengths and weaknesses of the available literature on the topic. Although LEGO® -based therapy appears a promising treatment for social interaction in ASD, the findings of LEGO® -based therapy studies should be interpreted and generalized with caution, due to the low quality of the studies and the small sample sizes. [ABSTRACT FROM AUTHOR]- Published
- 2021
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20. Autism Spectrum Disorder and Disruptive Behavior Disorders Comorbidities Delineate Clinical Phenotypes in Attention-Deficit Hyperactivity Disorder: Novel Insights from the Assessment of Psychopathological and Neuropsychological Profiles.
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Sesso, Gianluca, Cristofani, Chiara, Berloffa, Stefano, Cristofani, Paola, Fantozzi, Pamela, Inguaggiato, Emanuela, Narzisi, Antonio, Pfanner, Chiara, Ricci, Federica, Tacchi, Annalisa, Valente, Elena, Viglione, Valentina, Milone, Annarita, and Masi, Gabriele
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BEHAVIOR disorders ,ATTENTION-deficit hyperactivity disorder ,AUTISM spectrum disorders ,NEUROPSYCHOLOGICAL tests ,METACOGNITIVE therapy ,CHILD Behavior Checklist - Abstract
Although childhood-onset psychiatric disorders are often considered as distinct and separate from each other, they frequently co-occur, with partial overlapping symptomatology. Autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) commonly co-occur with each other and with other mental disorders, particularly disruptive behavior disorders, oppositional defiant disorder/conduct disorder (ODD/CD). Whether these associated comorbidities represent a spectrum of distinct clinical phenotypes is matter of research. The aim of our study was to describe the clinical phenotypes of youths with ADHD with and without ASD and/or ODD/CD, based on neuropsychological and psychopathological variables. One-hundred fifty-one participants with ADHD were prospectively recruited and assigned to four clinical groups, and assessed by means of parent-reported questionnaires, the child behavior checklist and the behavior rating inventory of executive functions. The ADHD alone group presented a greater impairment in metacognitive executive functions, ADHD+ASD patients presented higher internalizing problems and deficits in Shifting tasks, and ADHD+ODD/CD subjects presented emotional-behavioral dysregulation. Moreover, ADHD+ASD+ODD/CD individuals exhibited greater internalizing and externalizing problems, and specific neuropsychological impairments in the domains of emotional regulation. Our study supports the need to implement the evaluation of the psychopathological and neuropsychological functioning profiles, and to characterize specific endophenotypes for a finely customized establishment of treatment strategies. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
- View/download PDF
21. The Role of Executive Functions in the Development of Empathy and Its Association with Externalizing Behaviors in Children with Neurodevelopmental Disorders and Other Psychiatric Comorbidities.
- Author
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Cristofani, Chiara, Sesso, Gianluca, Cristofani, Paola, Fantozzi, Pamela, Inguaggiato, Emanuela, Muratori, Pietro, Narzisi, Antonio, Pfanner, Chiara, Pisano, Simone, Polidori, Lisa, Ruglioni, Laura, Valente, Elena, Masi, Gabriele, and Milone, Annarita
- Subjects
EXTERNALIZING behavior ,CHILDREN with autism spectrum disorders ,BEHAVIOR disorders in children ,ATTENTION-deficit hyperactivity disorder ,COMORBIDITY ,EMPATHY ,MENTAL illness - Abstract
Executive functions have been previously shown to correlate with empathic attitudes and prosocial behaviors. People with higher levels of executive functions, as a whole, may better regulate their emotions and reduce perceived distress during the empathetic processes. Our goal was to explore the relationship between empathy and executive functioning in a sample of children and adolescents diagnosed with Attention Deficit and Hyperactivity Disorder alone or associated with comorbid Disruptive Behavior Disorders and/or Autism Spectrum Disorder. We also aimed to examine the role of empathic dimensions and executive skills in regulating externalizing behaviors. The 151 participants with ADHD were assigned to four groups according to their psychiatric comorbidity (either "pure" or with ASD and/or ODD/CD) and assessed by means of either parent- or self-reported questionnaires, namely the BRIEF−2, the BES, and the IRI. No questionnaire was found to discriminate between the four groups. Affective Empathy was found to positively correlate with Emotional and Behavioral Regulation competences. Furthermore, Aggressiveness and Oppositional Defiant Problems were positively associated with Executive Emotional and Behavioral Regulation competences. On the other hand, Rule-Breaking Behaviors and Conduct Problems were negatively associated with Affective Empathy and with Behavioral skills. Our study provides an additional contribution for a better understanding of the complex relationship between empathic competence and executive functions, showing that executive functioning and empathic attitudes interact with each other to regulate aggressive behaviors. This study further corroborates developmental models of empathy and their clinical implications, for which externalizing behaviors could be attenuated by enhancing executive functioning skills. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
- View/download PDF
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