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1. Mouse Sycp1 functions in synaptonemal complex assembly, meiotic recombination, and XY body formation

Author

Femke A.T. de Vries, Esther de Boer, Bosch, Mike van den, Baarends, Willy M., Ooms, Marja, Li Yuan, Zeeland, Albert A. van, Jian-Guo Liu, Christa Heyting, and Pastink, Albert

Subjects
Genetic code -- Research, Human chromosome 21 -- Research, Meiosis -- Research, Biological sciences
Abstract

The mouse gene is disrupted encoding transverse filaments (TF) protein Sycp1 to analyze the role TFs in meiotic chromosome behavior and recombination. It is proposed that SYCP1 has a coordinating role, and ensures formation of crossovers.

Published
2005

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