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1,101 results on '"Liu, Xiangyu"'

7. Mobile Breast Cancer e-Support Program for Chinese Women With Breast Cancer Undergoing Chemotherapy (Part 2): Multicenter Randomized Controlled Trial

Author

Zhu, Jiemin, Ebert, Lyn, Liu, Xiangyu, Wei, Di, and Chan, Sally Wai-Chi

Subjects
Information technology, T58.5-58.64, Public aspects of medicine, RA1-1270
Abstract

BackgroundWomen undergoing chemotherapy for the treatment of breast cancer have frequently reported unmet supportive care needs. Moreover, easily accessible and innovative support is lacking. ObjectiveThe purpose of this trial was to determine the effectiveness of an app-based breast cancer e-support program to address women’s self-efficacy (primary outcome), social support, symptom distress, quality of life, anxiety, and depression. Secondary objectives included exploring the association between women’s health outcomes and the breast cancer e-support usage data. MethodsA multicenter, single-blinded, randomized controlled trial was conducted. A total of 114 women with breast cancer, who were commencing chemotherapy and were able to access internet through a mobile phone, were recruited in the clinics from 2 university-affiliated hospitals in China. Women were randomized either to the intervention group (n=57) receiving breast cancer e-support plus care as usual or the control group (n=57) receiving care as usual alone. The health care team and research assistants collecting data were blinded to the women’s group allocation. Bandura’s self-efficacy theory and the social exchange theory guided the development of the breast cancer e-support program, which has 4 components: (1) a Learning forum, (2) a Discussion forum, (3) an Ask-the-Expert forum, and (4) a Personal Stories forum. Moderated by an experienced health care professional, the breast cancer e-support program supported women for 12 weeks covering 4 cycles of chemotherapy. Health outcomes were self-assessed through paper questionnaires in clinics at baseline before randomization (T0), after 3 (T1), and 6 months (T2) of follow-ups. ResultsFifty-five participants in the intervention group and 49 in the control group completed the follow-up assessments (response rate: 91.2%). During the 12-week intervention, the log-in frequency ranged from 0 to 774 times (mean 54.7; SD 131.4; median 11; interquartile range, IQR 5-27), and the total usage duration ranged from 0 to 9371 min (mean 1072.3; SD 2359.5; median 100; IQR 27-279). Repeated measures multivariate analysis of covariance (intention-to-treat) found that breast cancer e-support + care as usual participants had significant better health outcomes at 3 months regarding self-efficacy (21.05; 95% CI 1.87-40.22; P=.03; d=0.53), symptom interference (−0.73; 95% CI −1.35 to −.11; P=.02; d=−0.51), and quality of life (6.64; 95% CI 0.77-12.50; P=.03, d=0.46) but not regarding social support, symptom severity, anxiety, and depression compared with care as usual participants. These beneficial effects were not sustained at 6 months. Spearman rank-order correlation showed that the breast cancer e-support usage duration was positively correlated with self-efficacy (r=.290, P=.03), social support (r=.320, P=.02), and quality of life (r=.273, P=.04) at 3 months. ConclusionsThe breast cancer e-support program demonstrated its potential as an effective and easily accessible intervention to promote women’s self-efficacy, symptom interference, and quality of life during chemotherapy. Trial RegistrationAustralian New Zealand Clinical Trials Registry (ANZCTR): ACTRN12616000639426; www.ANZCTR.org.au/ACTRN12616000639426.aspx (Archived by Webcite at http://www.webcitation.org/6v1n9hGZq)

Published
2018
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24. Model Design of Weapon Target Assignment System Based on Multi-Mode Fusion

Author

Liu Xiangyu, Zhu Kun, Wang Gang, Guo Xiangke, Fu Qiang, Li Tengda

Subjects
weapon target assignment, us department of defense architecture framework, petri net, other allocation, self-allocation, command and control, model design, Motor vehicles. Aeronautics. Astronautics, TL1-4050
Abstract

Target assignment is the core part in the command and control process, and the optimization of the allocation mode is of great significance for improving the air defense and anti-missile combat capability. In order to improve the robustness, applicability, game antagonism and other combat performance of air defense and anti-missile target allocation, so as to cope with the current complex and changeable battlefield environment, this paper proposes the target allocation architecture establishment of multi-mode fusion, and adaptively improve the commercial order-type service mode. The improvement of three kinds of dispatching models, that are “dispatching order” “grabbing order” and “dispatching- grabbing order fusion”, are defined as military models. By using the US department of defense architecture framework (DoDAF) to establish a new target allocation architecture of “other allocation” “self-allocation”and “combination of other allocation and self-allocation”. With the introduction of Perti net model, the reachable map of Petri net model is constructed and analyzed. Through the simulation experiment platform, the complex combat scenario is constructed to verify the feasibility of the distribution strategy mechanism. The results show that each of the three strategies has its own advantages. The multi-strategy combination designed in this paper has greater advantages than the traditional single strategy in matching time, success rate and utility value.

Published
2024
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40. Symmetric inheritance of parental histones contributes to safeguarding the fate of mouse embryonic stem cells during differentiation

Author

Wen, Qing, Zhou, Jiaqi, Tian, Congcong, Li, Xinran, Song, Guibing, Gao, Yuan, Sun, Yaping, Ma, Chiyuan, Yao, Sitong, Liang, Xiaoyan, Kang, Xing, Wang, Nan, Yao, Yuan, Wang, Hongbao, Liang, Xiaohuan, Tang, Jialin, Offer, Steven M., Lei, Xiaohua, Yu, Chuanhe, Liu, Xiangyu, Liu, Zichuan, Wang, Zhiquan, and Gan, Haiyun

Published
2023
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