Search

Your search keyword '"McGowan, Suzanne"' showing total 216 results
Start Over Author "McGowan, Suzanne" Search Limiters Academic (Peer-Reviewed) Journals
216 results on '"McGowan, Suzanne"'

13. Unravelling long-term impact of water abstraction and climate change on endorheic lakes: A case study of Shortandy Lake in Central Asia.

Author

Baigaliyeva, Marzhan, Mount, Nick, Gosling, Simon N., and McGowan, Suzanne

Subjects
ENDORHEIC lakes, CLIMATE change, LAKES, NATURE parks, NATIONAL parks & reserves, WATER levels
Abstract

Endorheic lakes, lacking river outflows, are highly sensitive to environmental changes and human interventions. Central Asia (CA) has over 6000 lakes that have experienced substantial water level variability in the past century, yet causes of recent changes in many lakes remain unexplored. Modelling hydrological processes for CA lakes poses challenges in separating climatic change impacts from human management impacts due to limited data and long-term variability in hydrological regimes. This study developed a spatially lumped empirical model to investigate the effects of climate change and human water abstraction, using Shortandy Lake in Burabay National Nature Park (BNNP) as a case study. Modelling results show a significant water volume decline from 231.7x106m3 in 1986 to 172.5x106m3 in 2016, primarily driven by anthropogenic water abstraction, accounting for 92% of the total volume deficit. The highest rates of water abstraction (greater than 25% of annual outflow) occurred from 1989 to 1993, coinciding with the driest period. Since 2013, the water volume has increased due to increased precipitation and, more importantly, reduced water abstraction. Despite limited observational data with which to calibrate the model, it performs well. Our analysis underscores the challenges in modelling lakes in data-sparse regions such as CA, and highlights the importance and benefits of developing lake water balance models for the region. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

14. Tumor Biomechanics Alters Metastatic Dissemination of Triple Negative Breast Cancer via Rewiring Fatty Acid Metabolism.

Author

Filipe, Elysse C., Velayuthar, Sipiththa, Philp, Ashleigh, Nobis, Max, Latham, Sharissa L., Parker, Amelia L., Murphy, Kendelle J., Wyllie, Kaitlin, Major, Gretel S., Contreras, Osvaldo, Mok, Ellie T. Y., Enriquez, Ronaldo F., McGowan, Suzanne, Feher, Kristen, Quek, Lake‐Ee, Hancock, Sarah E., Yam, Michelle, Tran, Emmi, Setargew, Yordanos F. I., and Skhinas, Joanna N.

Subjects
TRIPLE-negative breast cancer, FATTY acids, BREAST, METASTASIS, BIOMECHANICS, METABOLISM, BREAST tumors
Abstract

In recent decades, the role of tumor biomechanics on cancer cell behavior at the primary site has been increasingly appreciated. However, the effect of primary tumor biomechanics on the latter stages of the metastatic cascade, such as metastatic seeding of secondary sites and outgrowth remains underappreciated. This work sought to address this in the context of triple negative breast cancer (TNBC), a cancer type known to aggressively disseminate at all stages of disease progression. Using mechanically tuneable model systems, mimicking the range of stiffness's typically found within breast tumors, it is found that, contrary to expectations, cancer cells exposed to softer microenvironments are more able to colonize secondary tissues. It is shown that heightened cell survival is driven by enhanced metabolism of fatty acids within TNBC cells exposed to softer microenvironments. It is demonstrated that uncoupling cellular mechanosensing through integrin β1 blocking antibody effectively causes stiff primed TNBC cells to behave like their soft counterparts, both in vitro and in vivo. This work is the first to show that softer tumor microenvironments may be contributing to changes in disease outcome by imprinting on TNBC cells a greater metabolic flexibility and conferring discrete cell survival advantages. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

15. Changing nutrient cycling in Lake Baikal, the world’s oldest lake

Author

Swann, George E. A., Panizzo, Virginia N., Piccolroaz, Sebastiano, Pashley, Vanessa, Horstwood, Matthew S. A., Roberts, Sarah, Vologina, Elena, Piotrowska, Natalia, Sturm, Michael, Zhdanov, Andre, Granin, Nikolay, Norman, Charlotte, McGowan, Suzanne, and Mackay, Anson W.

Published
2020

25. Transient social-ecological dynamics reveal signals of decoupling in a highly disturbed Anthropocene landscape.

Author

Qi Lin, Ke Zhang, Giguet-Covex, Charline, Arnaud, Fabien, McGowan, Suzanne, Gielly, Ludovic, Capo, Eric, Shixin Huang, Ficetola, Gentile Francesco, Ji Shen, Dearing, John A., and Meadows, Michael E.

Subjects
TRANSIENTS (Dynamics), FOSSIL DNA, SOIL erosion, WATERSHEDS, SYSTEM dynamics
Abstract

Understanding the transient dynamics of interlinked social-ecological systems (SES) is imperative for assessing sustainability in the Anthropocene. However, how to identify critical transitions in real-world SES remains a formidable challenge. In this study, we present an evolutionary framework to characterize these dynamics over an extended historical timeline. Our approach leverages multidecadal rates of change in socioeconomic data, paleoenvironmental, and cutting-edge sedimentary ancient DNA records from China's Yangtze River Delta, one of the most densely populated and intensively modified landscapes on Earth. Our analysis reveals two significant social-ecological transitions characterized by contrasting interactions and feedback spanning several centuries. Initially, the regional SES exhibited a loosely connected and ecologically sustainable regime. Nevertheless, starting in the 1950s, an increasingly interconnected regime emerged, ultimately resulting in the crossing of tipping points and an unprecedented acceleration in soil erosion, water eutrophication, and ecosystem degradation. Remarkably, the second transition occurring around the 2000s, featured a notable decoupling of socioeconomic development from ecoenvironmental degradation. This decoupling phenomenon signifies a more desirable reconfiguration of the regional SES, furnishing essential insights not only for the Yangtze River Basin but also for regions worldwide grappling with similar sustainability challenges. Our extensive multidecadal empirical investigation underscores the value of coevolutionary approaches in understanding and addressing social-ecological system dynamics. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

29. Recent ecological change in ancient lakes

Author

Hampton, Stephanie E., McGowan, Suzanne, Ozersky, Ted, Virdis, Salvatore G. P., Vu, Tuong Thuy, Spanbauer, Trisha L., Kraemer, Benjamin M., Swann, George, Mackay, Anson W., Powers, Stephen M., Meyer, Michael F., Labou, Stephanie G., O’Reilly, Catherine M., DiCarlo, Morgan, Galloway, Aaron W. E., and Fritz, Sherilyn C.

Published
2018

32. Investigating the role of hydrological connectivity on the processing of organic carbon in tropical aquatic ecosystems.

Author

Pereira, Ryan, Panizzo, Virginia N., Bischoff, Juliane, McGowan, Suzanne, Lacey, Jack, Moorhouse, Heather, Zelani, Noor Suhailis, Ruslan, Muhammad Shafiq, and Fazry, Shazrul

Subjects
TROPICAL ecosystems, WETLANDS, BODIES of water, DISSOLVED organic matter, HUMUS, HYDROLOGIC cycle, WETLAND soils
Abstract

Inland waters are highways of carbon and nutrient flows between the land and ocean. Aquatic environments integrate multiple sources and processes over space and time that influence ecosystem functionality. The complexity of these systems and their multiple interactions with the surrounding environment are conceptualised, but often lack empirical scrutiny that allows further understanding of how inland waters mobilise, transport, and utilise carbon and nutrients. This is particularly evident in tropical waters. Here, we apply advanced geochemical analyses of dissolved organic matter (DOM) composition in conjunction with algal pigment biomarkers, to determine the seasonal variability of organic matter production, processing and export for a tropical, floodpulse wetland, Tasik Chini (Malaysia). We identify two phases in the hydrological cycle: Phase 1 signifying a transition from the wet season with high suspended sediment and dissolved organic carbon concentrations. DOM is composed of humic substances, building blocks and lower molecular weight compounds. Towards the end this phase then are periods of increased water clarity and algal productivity. This is followed by Phase 2, which has a greater contribution of autochthonous DOM, composed of proteinaceous material, concomitant with lower dissolved nutrient concentrations, increased mixotrophic algae and emergent vegetation. Based on this framework, we highlight the role of such tropical wetland lakes as hydrological "bottlenecks," through a lentic/lotic switch that shifts aquatic transport of carbon and nutrients from lateral river continuum supply to flood pulses. We highlight the need to consider inherent biases of spatial and temporal scaling when examining freshwater ecosystems along the land-ocean aquatic continuum. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

37. The Arctic in the Twenty-First Century : Changing Biogeochemical Linkages across a Paraglacial Landscape of Greenland

Author

ANDERSON, N. JOHN, SAROS, JASMINE E., BULLARD, JOANNA E., CAHOON, SEAN M.P., MCGOWAN, SUZANNE, BAGSHAW, ELIZABETH A., BARRY, CHRISTOPHER D., BINDLER, RICHARD, BURPEE, BENJAMIN T., CARRIVICK, JONATHAN L., FOWLER, RACHEL A., FOX, ANTHONY D., FRITZ, SHERILYN C., GILES, MADELEINE E., HAMERLIK, LADISLAV, INGEMAN-NIELSEN, THOMAS, LAW, ANTONIA C., MERNILD, SEBASTIAN H., NORTHINGTON, ROBERT M., OSBURN, CHRISTOPHER L., PLA-RABÈS, SERGI, POST, ERIC, TELLING, JON, STROUD, DAVID A., WHITEFORD, ERIKA J., YALLOP, MARIAN L., and YDE, JACOB C.

Published
2017

43. Double‐edged effects of anthropogenic activities on lake ecological dynamics in northern China: Evidence from palaeolimnology and ecosystem modelling.

Author

Zhang, Can, Kong, Xiangzhen, Xue, Bin, Zhao, Cheng, McGowan, Suzanne, Lin, Qi, Zhang, Ke, and Shen, Ji

Subjects
ECOSYSTEM dynamics, ALGAL communities, ECOSYSTEMS, GLOBAL warming, BIOINDICATORS, RESTORATION ecology, EFFECT of human beings on climate change
Abstract

A bs tract: Climate change and anthropogenic activities mutually degraded global lake ecosystems during the Anthropocene. Nutrient mitigation via catchment management has been a constant priority for lake ecological restoration; however, the outcomes after mitigation remain uncertain. In particular, there is limited knowledge on the effects of large‐scale forest restoration and soil erosion reduction in catchments on the ecological dynamics of downstream aquatic systems.Here, we study a strategically chosen alpine lake from the Loess Plateau in northern China, which has been extensively afforested in the past decades. We present high‐resolution, multi‐proxy records to reconstruct environmental and ecological dynamics since 1960. To quantify the potential mechanisms, we combined evidence from palaeolimnological records, contemporary field observations and process‐based ecosystem modelling. We developed palaeorecord‐based proxies for water transparency, nutrient concentrations and algal composition, and applied these proxies to ecosystem modelling.Our results show that despite the concurrent decline in nutrient levels, the lake ecosystem has experienced large‐magnitude rapid shifts since 2000, characterised by unambiguously increased algae proliferation and community changes. The modelling results revealed that the reduction in soil erosion acts as a "double‐edged sword"; that is, lower external nutrient loading via soil erosion is ideal for in‐lake algae inhibition, whereas increasing light availability counteracts the reduced yet still sufficient nutrient concentrations and, ultimately, promotes temporary algal proliferation via extended habitats and intensive photosynthesis. Intriguingly, lake warming plays a secondary role in driving these ecological dynamics.Our results emphasised the unexpected algal proliferation when the nutrient level declined in lake ecosystems; thus, other compound factors, including water transparency and climate warming, need to be incorporated for reliable prediction and effective restoration. A multi‐disciplinary approach integrating palaeorecords as ecological indicators and process‐based ecosystem modelling holds great potential for investigating long‐term lake ecological dynamics in the context of rapid global changes. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

44. Looking forward through the past: identification of 50 priority research questions in palaeoecology

Author

Seddon, Alistair W. R., Mackay, Anson W., Baker, Ambroise G., Birks, H. John B., Breman, Elinor, Buck, Caitlin E., Ellis, Erle C., Froyd, Cynthia A., Gill, Jacquelyn L., Gillson, Lindsey, Johnson, Edward A., Jones, Vivienne J., Juggins, Stephen, Macias-Fauria, Marc, Mills, Keely, Morris, Jesse L., Nogués-Bravo, David, Punyasena, Surangi W., Roland, Thomas P., Tanentzap, Andrew J., Willis, Kathy J., Aberhan, Martin, van Asperen, Eline N., Austin, William E. N., Battarbee, Rick W., Bhagwat, Shonil, Belanger, Christina L., Bennett, Keith D., Birks, Hilary H., Ramsey, Christopher Bronk, Brooks, Stephen J., de Bruyn, Mark, Butler, Paul G., Chambers, Frank M., Clarke, Stewart J., Davies, Althea L., Dearing, John A., Ezard, Thomas H. G., Feurdean, Angelica, Flower, Roger J., Gell, Peter, Hausmann, Sonja, Hogan, Erika J., Hopkins, Melanie J., Jeffers, Elizabeth S., Korhola, Atte A., Marchant, Robert, Kiefer, Thorsten, Lamentowicz, Mariusz, Larocque-Tobler, Isabelle, López-Merino, Lourdes, Liow, Lee H., McGowan, Suzanne, Miller, Joshua H., Montoya, Encarni, Morton, Oliver, Nogué, Sandra, Onoufriou, Chloe, Boush, Lisa P., Rodriguez-Sanchez, Francisco, Rose, Neil L., Sayer, Carl D., Shaw, Helen E., Payne, Richard, Simpson, Gavin, Sohar, Kadri, Whitehouse, Nicki J., Williams, John W., and Witkowski, Andrzej

Published
2014

Catalog

Books, media, physical & digital resources
See catalog results