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143 results on '"Ramos, A.M."'

2. Pseudomonas aeruginosa bloodstream infections in children and adolescents: risk factors associated with carbapenem resistance and mortality

Author

Grasa, C., Sánchez Castellano, M., Rodríguez-Molino, P., Castro Martínez, M., de Llano, B.B.Q., San Juan, I., Rodríguez, N.E.G., Aguilera-Alonso, D., Escosa, L., Gómez-Gil, M.R., Manzanares, Á., Ascaso, M.G., Bermejo-Gómez, A., Abad, M.J.G., Ramos, A.M., Núñez, A.S., Orellana, M.Á., Cercenado, E., Lozano, J.S., Calvo, C., and Baquero-Artigao, F.

Published
2024
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6. Pseudomonas aeruginosa bloodstream infections in children and adolescents: risk factors associated with carbapenem resistance and mortality.

Author

Rodríguez, N.E.G., Aguilera-Alonso, D., Escosa, L., Gómez-Gil, M.R., Manzanares, Á., Ascaso, M.G., Bermejo-Gómez, A., Abad, M.J.G., Ramos, A.M., Núñez, A.S., Orellana, M.Á., Cercenado, E., Lozano, J.S., Calvo, C., and Baquero-Artigao, F.

Abstract

Pseudomonas aeruginosa bloodstream infections (PA-BSIs) are a serious disease and a therapeutic challenge due to increasing resistance to carbapenems. Our objectives were to describe the prevalence and risk factors associated with carbapenem resistance (CR) and mortality in children with PA-BSI. A retrospective, multi-centre study was carried out, including patients aged <20 years with PA-BSI in four tertiary hospitals in Madrid (Spain) during 2010–2020. Risk factors for CR PA-BSIs and 30-day mortality were evaluated in a multi-variable logistic regression model. In total, 151 patients with PA-BSI were included, with a median age of 29 months (interquartile range: 3.5–87.1). Forty-five (29.8%) cases were CR, 9.9% multi-drug resistant and 6.6% extensively drug resistant. The prevalence of CR remained stable throughout the study period, with 26.7% (12/45) of CR mediated by VIM-type carbapenemase. Patients with BSIs produced by CR-PA were more likely to receive inappropriate empiric treatment (53.3% vs 5.7%, P <0.001) and to have been previously colonized by CR-PA (8.9% vs 0%, P =0.002) than BSIs caused by carbapenem-susceptible P. aeruginosa. CR was associated with carbapenem treatment in the previous month (adjusted odds ratio (aOR) 11.15) and solid organ transplantation (aOR 7.64). The 30-day mortality was 23.2%, which was associated with mechanical ventilation (aOR 4.24), sepsis (aOR 5.72), inappropriate empiric antibiotic therapy (aOR 5.86), and source control as a protective factor (aOR 0.16). This study shows a concerning prevalence of CR in children with PA-BSIs, leading to high mortality. Inappropriate empiric treatment and sepsis were associated with mortality. The high prevalence of CR with an increased risk of inappropriate empiric treatment should be closely monitored. [ABSTRACT FROM AUTHOR]

Published
2024
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10. chapter 6: THE EXCEPTIONAL IBERIAN HEATWAVE OF SUMMER 2018

Author

Barriopedro, D., Sousa, P.M., Trigo, R.M., Garcia-Herrera, R., and Ramos, A.M.

Subjects
Summer -- Environmental aspects, Hot weather -- Environmental aspects, Business, Earth sciences
Abstract

August 2018 saw the warmest Iberian heatwave since that of 2003. Recent climate change has exacerbated this event making it at least [much greater than] 1[degrees]C warmer than similar events [...]

Published
2020
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49. Heating rates of peach juice in an agitated jacketed vessel

Author

Ibarz, A., Ramos, A.M., Puig-Bargues, J., and Barbosa-Canovas, G.V.

Subjects
Peach -- Research, Fruit juices -- Production processes, Thermodynamics -- Case studies, Business, Food/cooking/nutrition
Abstract

An experiment was conducted to determine heat transfer coefficients and heat transfer rates at varying agitation rates in peach juices warmed in an agitated jacketed vessel containing different agitators rate and to establish the relationships between heat transfer and power. Two equations were derived for the density and rheological behavior of peach juice based on the combined effects of temperature and soluble solids content. The study and its results are discussed.

Published
1998

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