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10 results on '"Regidor, Carmen"'

1. Haplo-Cord Transplantation Using CD34+ Cells from a Third-Party Donor to Speed Engraftment in High-Risk Patients with Hematologic Disorders

Author

Kwon, Mi, Bautista, Guiomar, Balsalobre, Pascual, Sánchez-Ortega, Isabel, Serrano, David, Anguita, Javier, Buño, Ismael, Fores, Rafael, Regidor, Carmen, García Marco, José A., Vilches, Carlos, de Pablo, Rosario, Fernández, Manuel N., Gayoso, Jorge, Duarte, Rafael, Díez-Martín, José Luis, and Cabrera, Rafael

Published
2014
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3. Haematopoietic transplants combining a single unrelated cord blood unit and mobilized haematopoietic stem cells from an adult HLA-mismatched third party donor.: Comparable results to transplants from HLA-identical related donors in adults with acute leukaemia and myelodysplastic syndromes

Author

Sebrango, Ana, Vicuña, Isabel, de Laiglesia, Almudena, Millán, Isabel, Bautista, Guiomar, Martín-Donaire, Trinidad, Regidor, Carmen, Cabrera, Rafael, and Fernandez, Manuel N.

Published
2010
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4. Results of a pilot study on the use of third-party donor mesenchymal stromal cells in cord blood transplantation in adults

Author

Gonzalo-Daganzo, Rosa, Regidor, Carmen, Martín-Donaire, Trinidad, Rico, Miguel Angel, Bautista, Guiomar, Krsnik, Isabel, Forés, Rafael, Ojeda, Emilio, Sanjuán, Isabel, García-Marco, José A., Navarro, Belén, Gil, Santiago, Sánchez, Rocío, Panadero, Nuria, Gutiérrez, Yolanda, García-Berciano, Miguel, Pérez, Nuria, Millán, Isabel, Cabrera, Rafael, and Fernández, Manuel N.

Published
2009
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8. Unrelated umbilical cord blood transplants in adults: Early recoveryof neutrophils by supportive co-transplantation of a low number of highlypurified peripheral blood CD34+ cells from an HLA-haploidentical donor

Author

Fernández, Manuel N., Regidor, Carmen, Cabrera, Rafael, García-Marco, José A., Forés, Rafael, Sanjuán, Isabel, Gayoso, Jorge, Gil, Santiago, Ruíz, Elena, Little, Ann-Margaret, McWhinnie, Alasdair, and Madrigal, Alejandro

Subjects
*NEUTROPENIA, *BLOOD cells
Abstract

Objective, Methods, and Results. To reduce the period of posttransplant neutropenia and related early morbidity and mortality of cord blood (CB) transplants, we assessed the feasibility of co-infusion of a low number of highly purified peripheral blood CD34+ cells from a related haploidentical donor with a CB graft. Between March 1999 and May 2002, 11 patients with high-risk hematologic malignancies were transplanted using this strategy. The seven patients who received a haploidentical peripheral blood graft and a CB graft from a sibling (6) or the father (1) had prompt recovery (9–17 days, median 10) of the absolute neutrophil count (ANC) to greater than 0.5×109/L. Analysis of DNA polymorphisms showed initial predominance of the haploidentical genotype both in granulocytes and in mononuclear cells, and subsequent progressive replacement by cells of CB genotype until final complete CB chimerism was achieved by patients who survived for sufficient periods of time. The four patients who received maternal haploidentical cells had no significant contribution of these to blood leukocytes, although complete CB chimerism was achieved by three of them and two reached engraftment of the CB on days +20 and +36. Morbidity due to early bacterial or fungal infections was remarkably low in patients with prompt ANC recovery.Conclusion. Our data show that co-infusion of a CB unit and a low number of haploidentical CD34+ cells may result in a shortened period of posttransplant neutropenia. This is likely the result of prompt and transient engraftment of the haploidentical hematopoietic stem cells that may provide the patient antimicrobial protection until the later engraftment of the CBhematopoietic stem cells. [Copyright &y& Elsevier]

Published
2003
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9. 204 - Single Cord Blood Unit Plus Third Party Donor Cells (Haplo-Cord) Transplantation Compared to Adult Unrelated Donors in Patients with Acute Leukemia: A Retrospective Case-Control Study.

Author

Bautista, Guiomar, Canals, Carmen, Kwon, Mi, Sanchez-Ortega, Isabel, Regidor, Carmen, Balsalobre, Pascual, Bermúdez, Arancha, Rovira, Montserrat, Diez-Martin, José Luis, de Laiglesia, Almudena, Pérez-Simón, José Antonio, Yañez, Lucrecia, Ferrá, Christelle, Sierra, Jorge, Bello, Jose Luis, Herrera-Arroyo, Inmaculada, Solano, Carlos, Pascual, Maria Jesús, Zudaire, Teresa, and López-Corral, Lucía

Published
2018
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10. 138 - Comparison of Single Unmanipulated Umbilical Cord Blood or Co-Infusion of an Umbilical Cord Blood Graft with CD34+ Cells From a Third Party Donor in Adults with Acute Leukemia.

Author

Sanz, Jaime, Kwon, Mi, Bautista, Guiomar, Sanz, Miguel A., Balsalobre, Pascual, Piñana, José Luis, Solano, Carlos, Duarte, Rafael F., Ferrá, Christelle, Martín, Carmen, Barba, Pere, Pascual, Maria Jesús, Martino, Rodrigo, Gayoso, Jorge, Regidor, Carmen, de la Iglesia, Almudena, Montoro, Juan, Diez-Martin, José Luis, Sanz, Guillermo, and Cabrera, Rafael

Subjects
*ACUTE leukemia, *CORD blood transplantation, *CD3 antigen, *NEUTROPHILS, *LEUKEMIA treatment, DISEASES in adults
Published
2017
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