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1,039 results on '"Rossini, Paolo"'

6. Bringing sensation to prosthetic hands—chronic assessment of implanted thin-film electrodes in humans

Author

Čvančara, Paul, Valle, Giacomo, Müller, Matthias, Bartels, Inga, Guiho, Thomas, Hiairrassary, Arthur, Petrini, Francesco, Raspopovic, Stanisa, Strauss, Ivo, Granata, Giuseppe, Fernandez, Eduardo, Rossini, Paolo M., Barbaro, Massimo, Yoshida, Ken, Jensen, Winnie, Divoux, Jean-Louis, Guiraud, David, Micera, Silvestro, and Stieglitz, Thomas

Published
2023
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11. Development of a prediction model of conversion to Alzheimer’s disease in people with mild cognitive impairment: the statistical analysis plan of the INTERCEPTOR project

Author

Lombardo, Flavia L., Lorenzini, Patrizia, Mayer, Flavia, Massari, Marco, Piscopo, Paola, Bacigalupo, Ilaria, Ancidoni, Antonio, Sciancalepore, Francesco, Locuratolo, Nicoletta, Remoli, Giulia, Salemme, Simone, Cappa, Stefano, Perani, Daniela, Spadin, Patrizia, Tagliavini, Fabrizio, Redolfi, Alberto, Cotelli, Maria, Marra, Camillo, Caraglia, Naike, Vecchio, Fabrizio, Miraglia, Francesca, Rossini, Paolo Maria, and Vanacore, Nicola

Published
2024
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13. Clinical diagnostic utility of transcranial magnetic stimulation in neurological disorders. Updated report of an IFCN committee

Author

Vucic, Steve, Stanley Chen, Kai-Hsiang, Kiernan, Matthew C., Hallett, Mark, Benninger, David.H., Di Lazzaro, Vincenzo, Rossini, Paolo M, Benussi, Alberto, Berardelli, Alfredo, Currà, Antonio, Krieg, Sandro M, Lefaucheur, Jean-Pascal, Long Lo, Yew, Macdonell, Richard A, Massimini, Marcello, Rosanova, Mario, Picht, Thomas, Stinear, Cathy M, Paulus, Walter, Ugawa, Yoshikazu, Ziemann, Ulf, and Chen, Robert

Published
2023
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16. BDNF Val66Met gene polymorphism modulates brain activity following rTMS-induced memory impairment

Author

Abellaneda-Pérez, Kilian, Martin-Trias, Pablo, Cassé-Perrot, Catherine, Vaqué-Alcázar, Lídia, Lanteaume, Laura, Solana, Elisabeth, Babiloni, Claudio, Lizio, Roberta, Junqué, Carme, Bargalló, Núria, Rossini, Paolo Maria, Micallef, Joëlle, Truillet, Romain, Charles, Estelle, Jouve, Elisabeth, Bordet, Régis, Santamaria, Joan, Rossi, Simone, Pascual-Leone, Alvaro, Blin, Olivier, Richardson, Jill, Jovicich, Jorge, and Bartrés-Faz, David

Published
2022
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20. Non-invasive brain stimulation and neuroenhancement

Author

Antal, Andrea, Luber, Bruce, Brem, Anna-Katharine, Bikson, Marom, Brunoni, Andre R., Cohen Kadosh, Roi, Dubljević, Veljko, Fecteau, Shirley, Ferreri, Florinda, Flöel, Agnes, Hallett, Mark, Hamilton, Roy H., Herrmann, Christoph S., Lavidor, Michal, Loo, Collen, Lustenberger, Caroline, Machado, Sergio, Miniussi, Carlo, Moliadze, Vera, Nitsche, Michael A, Rossi, Simone, Rossini, Paolo M., Santarnecchi, Emiliano, Seeck, Margitta, Thut, Gregor, Turi, Zsolt, Ugawa, Yoshikazu, Venkatasubramanian, Ganesan, Wenderoth, Nicole, Wexler, Anna, Ziemann, Ulf, and Paulus, Walter

Published
2022
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21. Associations Between Free and Cued Selective Reminding Test and Cerebrospinal Fluid Biomarkers in Amnestic Mild Cognitive Impairment.

Author

Giuffrè, Guido Maria, Quaranta, Davide, Citro, Salvatore, Morganti, Tommaso Giuseppe, Martellacci, Noemi, Vita, Maria Gabriella, Rossini, Paolo Maria, Calabresi, Paolo, and Marra, Camillo

Subjects
AMNESTIC mild cognitive impairment, CEREBROSPINAL fluid, MILD cognitive impairment, EPISODIC memory, BIOMARKERS, MEMORY disorders, VERBAL memory
Abstract

Background: The Free and Cued Selective Reminding Test (FCSRT), assessing verbal episodic memory with controlled learning and semantic cueing, has been recommended for detecting the genuine encoding and storage deficits characterizing AD-related memory disorders. Objective: The present study aims at investigating the ability of FCSRT in predicting cerebrospinal fluid (CSF) evidence of amyloid-β positivity in subjects with amnestic mild cognitive impairment (aMCI) and exploring its associations with amyloidopathy, tauopathy and neurodegeneration biomarkers. Methods: 120 aMCI subjects underwent comprehensive neurological and neuropsychological examinations, including the FCSRT assessment, and CSF collection; CSF Aβ42/40 ratio, p-tau181, and total-tau quantification were conducted by an automated CLEIA method on Lumipulse G1200. Based on the Aβ42/40 ratio value, subjects were classified as either A+ or A–. Results: All FCSRT subitem scores were significantly lower in A+ group and significantly predicted the amyloid-β status, with Immediate Total Recall (ITR) being the best predictor. No significant correlations were found between FCSRT and CSF biomarkers in the A– aMCI group, while in the A+ aMCI group, all FCSRT subitem scores were negatively correlated with CSF p-tau181 and total-tau, but not with the Aβ42/40 ratio. Conclusions: FCSRT confirms its validity as a tool for the diagnosis of AD, being able to predict the presence of amyloid-β deposition with high specificity. The associations between FCSRT subitem scores and CSF p-tau-181 and total-tau levels in aMCI due to AD could further encourage the clinical use of this simple and cost-effective test in the evaluation of individuals with aMCI. [ABSTRACT FROM AUTHOR]

Published
2024
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22. Small World derived index to distinguish Alzheimer's type dementia and healthy subjects.

Author

Vecchio, Fabrizio, Miraglia, Francesca, Pappalettera, Chiara, Nucci, Lorenzo, Cacciotti, Alessia, and Rossini, Paolo Maria

Subjects
BRAIN physiology, RISK assessment, ALZHEIMER'S disease, ELECTROENCEPHALOGRAPHY, DESCRIPTIVE statistics, PSYCHOLOGY of movement, NEUROPSYCHOLOGY, NEUROPSYCHOLOGICAL tests, ONE-way analysis of variance, DEMENTIA, DATA analysis software, MACHINE learning, BIOMARKERS
Abstract

Background This article introduces a novel index aimed at uncovering specific brain connectivity patterns associated with Alzheimer's disease (AD), defined according to neuropsychological patterns. Methods Electroencephalographic (EEG) recordings of 370 people, including 170 healthy subjects and 200 mild-AD patients, were acquired in different clinical centres using different acquisition equipment by harmonising acquisition settings. The study employed a new derived Small World (SW) index, SWcomb, that serves as a comprehensive metric designed to integrate the seven SW parameters, computed across the typical EEG frequency bands. The objective is to create a unified index that effectively distinguishes individuals with a neuropsychological pattern compatible with AD from healthy ones. Results Results showed that the healthy group exhibited the lowest SWcomb values, while the AD group displayed the highest SWcomb ones. Conclusions These findings suggest that SWcomb index represents an easy-to-perform, low-cost, widely available and non-invasive biomarker for distinguishing between healthy individuals and AD patients. [ABSTRACT FROM AUTHOR]

Published
2024
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25. Training in the practice of noninvasive brain stimulation: Recommendations from an IFCN committee

Author

Fried, Peter J., Santarnecchi, Emiliano, Antal, Andrea, Bartres-Faz, David, Bestmann, Sven, Carpenter, Linda L., Celnik, Pablo, Edwards, Dylan, Farzan, Faranak, Fecteau, Shirley, George, Mark S., He, Bin, Kim, Yun-Hee, Leocani, Letizia, Lisanby, Sarah H., Loo, Colleen, Luber, Bruce, Nitsche, Michael A., Paulus, Walter, Rossi, Simone, Rossini, Paolo M., Rothwell, John, Sack, Alexander T., Thut, Gregor, Ugawa, Yoshikazu, Ziemann, Ulf, Hallett, Mark, and Pascual-Leone, Alvaro

Published
2021
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26. Accuracy and reproducibility of automated white matter hyperintensities segmentation with lesion segmentation tool: A European multi-site 3T study

Author

Ribaldi, Federica, Altomare, Daniele, Jovicich, Jorge, Ferrari, Clarissa, Picco, Agnese, Pizzini, Francesca Benedetta, Soricelli, Andrea, Mega, Anna, Ferretti, Antonio, Drevelegas, Antonios, Bosch, Beatriz, Müller, Bernhard W., Marra, Camillo, Cavaliere, Carlo, Bartrés-Faz, David, Nobili, Flavio, Alessandrini, Franco, Barkhof, Frederik, Gros-Dagnac, Helene, Ranjeva, Jean-Philippe, Wiltfang, Jens, Kuijer, Joost, Sein, Julien, Hoffmann, Karl-Titus, Roccatagliata, Luca, Parnetti, Lucilla, Tsolaki, Magda, Constantinidis, Manos, Aiello, Marco, Salvatore, Marco, Montalti, Martina, Caulo, Massimo, Didic, Mira, Bargallo, Núria, Blin, Olivier, Rossini, Paolo M, Schonknecht, Peter, Floridi, Piero, Payoux, Pierre, Visser, Pieter Jelle, Bordet, Régis, Lopes, Renaud, Tarducci, Roberto, Bombois, Stephanie, Hensch, Tilman, Fiedler, Ute, Richardson, Jill C., Frisoni, Giovanni B., and Marizzoni, Moira

Published
2021
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27. Safety and recommendations for TMS use in healthy subjects and patient populations, with updates on training, ethical and regulatory issues: Expert Guidelines

Author

Rossi, Simone, Antal, Andrea, Bestmann, Sven, Bikson, Marom, Brewer, Carmen, Brockmöller, Jürgen, Carpenter, Linda L., Cincotta, Massimo, Chen, Robert, Daskalakis, Jeff D., Di Lazzaro, Vincenzo, Fox, Michael D., George, Mark S., Gilbert, Donald, Kimiskidis, Vasilios K., Koch, Giacomo, Ilmoniemi, Risto J., Lefaucheur, Jean Pascal, Leocani, Letizia, Lisanby, Sarah H., Miniussi, Carlo, Padberg, Frank, Pascual-Leone, Alvaro, Paulus, Walter, Peterchev, Angel V., Quartarone, Angelo, Rotenberg, Alexander, Rothwell, John, Rossini, Paolo M., Santarnecchi, Emiliano, Shafi, Mouhsin M., Siebner, Hartwig R., Ugawa, Yoshikatzu, Wassermann, Eric M., Zangen, Abraham, Ziemann, Ulf, and Hallett, Mark

Published
2021
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30. Amygdalar nuclei and hippocampal subfields on MRI: Test-retest reliability of automated volumetry across different MRI sites and vendors

Author

Quattrini, Giulia, Pievani, Michela, Jovicich, Jorge, Aiello, Marco, Bargalló, Núria, Barkhof, Frederik, Bartres-Faz, David, Beltramello, Alberto, Pizzini, Francesca B., Blin, Olivier, Bordet, Regis, Caulo, Massimo, Constantinides, Manos, Didic, Mira, Drevelegas, Antonios, Ferretti, Antonio, Fiedler, Ute, Floridi, Piero, Gros-Dagnac, Hélène, Hensch, Tilman, Hoffmann, Karl-Titus, Kuijer, Joost P., Lopes, Renaud, Marra, Camillo, Müller, Bernhard W., Nobili, Flavio, Parnetti, Lucilla, Payoux, Pierre, Picco, Agnese, Ranjeva, Jean-Philippe, Roccatagliata, Luca, Rossini, Paolo M., Salvatore, Marco, Schonknecht, Peter, Schott, Björn H., Sein, Julien, Soricelli, Andrea, Tarducci, Roberto, Tsolaki, Magda, Visser, Pieter J., Wiltfang, Jens, Richardson, Jill C., Frisoni, Giovanni B., and Marizzoni, Moira

Published
2020
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33. Networks as interpretative frameworks: using co-citation analysis to explore large corpora of early modern letters.

Author

Rossini, Paolo

Subjects
*SCIENTIFIC Revolution, *HISTORICAL source material, *CORPORA, *DATABASES, *LANDSCAPE assessment, *COINTEGRATION, *ELECTRONIC publications, *SCIENTOMETRICS
Abstract

The analysis of co-citations, which occurs when two publications or authors are mentioned together in the same text, has long been established as a practice within scientometrics, particularly in the field of "science mapping". However, historiography has shown less openness to utilizing co-citation analysis for distant reading purposes. To address this gap, this article presents a comprehensive methodology for applying co-citation analysis to extensive collections of historical documents, specifically 17th-century letters indexed in the ePistolarium database. In science mapping, co-citation serves as an indicator for tracking the development of scientific fields. Similarly, I employ co-citation to map the Dutch socio-intellectual landscape during the Scientific Revolution period (1623–87) and evaluate the strengths and limitations of this approach. [ABSTRACT FROM AUTHOR]

Published
2024
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35. CSF cutoffs for MCI due to AD depend on APOEε4 carrier status

Author

Marizzoni, Moira, Ferrari, Clarissa, Babiloni, Claudio, Albani, Diego, Barkhof, Frederik, Cavaliere, Libera, Didic, Mira, Forloni, Gianluigi, Fusco, Federica, Galluzzi, Samantha, Hensch, Tilman, Jovicich, Jorge, Marra, Camillo, Molinuevo, José Luis, Nobili, Flavio, Parnetti, Lucilla, Payoux, Pierre, Ranjeva, Jean-Philippe, Ribaldi, Federica, Rolandi, Elena, Rossini, Paolo Maria, Salvatore, Marco, Soricelli, Andrea, Tsolaki, Magda, Visser, Pieter Jelle, Wiltfang, Jens, Richardson, Jill C., Bordet, Régis, Blin, Olivier, and Frisoni, Giovanni B.

Published
2020
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44. The role of the sleep K‐complex on the conversion from mild cognitive impairment to Alzheimer's disease.

Author

Gorgoni, Maurizio, Cenani, Jessica, Scarpelli, Serena, D'Atri, Aurora, Alfonsi, Valentina, Annarumma, Ludovica, Pietrogiacomi, Francesco, Ferrara, Michele, Marra, Camillo, Rossini, Paolo Maria, and De Gennaro, Luigi

Subjects
MILD cognitive impairment, ALZHEIMER'S disease, NON-REM sleep, SLOW wave sleep, BRAIN diseases
Abstract

Summary: The present literature points to an alteration of the human K‐complex during non‐rapid eye movement sleep in Alzheimer's disease. Nevertheless, the few findings on the K‐complex changes in mild cognitive impairment and their possible predictive role on the Alzheimer's disease conversion show mixed findings, lack of replication, and a main interest for the frontal region. The aim of the present study was to assess K‐complex measures in amnesic mild cognitive impairment subsequently converted in Alzheimer's disease over different cortical regions, comparing them with healthy controls and stable amnesic mild cognitive impairment. We assessed baseline K‐complex density, amplitude, area under the curve and overnight changes in frontal, central and parietal midline derivations of 12 amnesic mild cognitive impairment subsequently converted in Alzheimer's disease, 12 stable amnesic mild cognitive impairment and 12 healthy controls. We also assessed delta electroencephalogram power, to determine if K‐complex alterations in amnesic mild cognitive impairment occur with modification of the electroencephalogram power in the frequency range of the slow‐wave activity. We found a reduced parietal K‐complex density in amnesic mild cognitive impairment subsequently converted in Alzheimer's disease compared with stable amnesic mild cognitive impairment and healthy controls, without changes in K‐complex morphology and overnight modulation. Both amnesic mild cognitive impairment groups showed decreased slow‐wave sleep percentage compared with healthy controls. No differences between groups were observed in slow‐wave activity power. Our findings suggest that K‐complex alterations in mild cognitive impairment may be observed earlier in parietal regions, likely mirroring the topographical progression of Alzheimer's disease‐related brain pathology, and express a frontal predominance only in a full‐blown phase of Alzheimer's disease. Consistently with previous results, such K‐complex modification occurs in the absence of significant electroencephalogram power changes in the slow oscillations range. [ABSTRACT FROM AUTHOR]

Published
2024
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45. FDG‐PET markers of heterogeneity and different risk of progression in amnestic MCI.

Author

Caminiti, Silvia Paola, De Francesco, Silvia, Tondo, Giacomo, Galli, Alice, Redolfi, Alberto, Perani, Daniela, Cappa, Stefano F., Cotelli, Maria, Marra, Camillo, Rossini, Paolo Maria, Spadin, Patrizia, Tagliavini, Fabrizio, Vanacore, Nicola, and Vecchio, Fabrizio

Abstract

INTRODUCTION: Amnestic mild cognitive impairment (aMCI) is emerging as a heterogeneous condition. METHODS: We looked at a cohort of N = 207 aMCI subjects, with baseline fluorodeoxyglucose positron emission tomography (FDG‐PET), T1 magnetic resonance imaging, cerebrospinal fluid (CSF), apolipoprotein E (APOE), and neuropsychological assessment. An algorithm based on FDG‐PET hypometabolism classified each subject into subtypes, then compared biomarker measures and clinical progression. RESULTS: Three subtypes emerged: hippocampal sparing–cortical hypometabolism, associated with younger age and the highest level of Alzheimer's disease (AD)‐CSF pathology; hippocampal/cortical hypometabolism, associated with a high percentage of APOE ε3/ε4 or ε4/ε4 carriers; medial–temporal hypometabolism, characterized by older age, the lowest AD‐CSF pathology, the most severe hippocampal atrophy, and a benign course. Within the whole cohort, the severity of temporo‐parietal hypometabolism, correlated with AD‐CSF pathology and marked the rate of progression of cognitive decline. DISCUSSION: FDG‐PET can distinguish clinically comparable aMCI at single‐subject level with different risk of progression to AD dementia or stability. The obtained results can be useful for the optimization of pharmacological trials and automated‐classification models. Highlights: Algorithm based on FDG‐PET hypometabolism demonstrates distinct subtypes across aMCI;Three different subtypes show heterogeneous biological profiles and risk of progression;The cortical hypometabolism is associated with AD pathology and cognitive decline;MTL hypometabolism is associated with the lowest conversion rate and CSF‐AD pathology. [ABSTRACT FROM AUTHOR]

Published
2024
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46. Informal caregiver's socio demographic profile for community-dwelling women and men with mild to moderate Alzheimer's disease, compliance, and satisfaction to treatment: A post-hoc analysis of the AXEPT study.

Author

Colombo, Delia, Zagni, Emanuela, Rossini, Paolo Maria, Di Cioccio, Luigi, Gragnaniello, Daniela, Luda Di Cortemiglia, Emilio, Attar, Mahmood, Simoni, Lucia, Haggiag, Shalom, and Bernabei, Roberto

Subjects
ALZHEIMER'S disease treatment, RESEARCH, STATISTICS, PSYCHOLOGY of men, SCIENTIFIC observation, CROSS-sectional method, PATIENT satisfaction, SATISFACTION, FISHER exact test, T-test (Statistics), PSYCHOLOGY of caregivers, INDEPENDENT living, PSYCHOLOGY of women, CHI-squared test, DESCRIPTIVE statistics, RESEARCH funding, SOCIODEMOGRAPHIC factors, PATIENT compliance, DATA analysis, LOGISTIC regression analysis, DATA analysis software
Abstract

In this post-hoc analysis of the AXEPT study, 855 patients were analyzed, 544 (63.6%) females. The mean (± SD) MMSE score in women vs men was 20.8 ± 2.6 vs. 21.2 ± 2.5; p = 0.0087, and women were more likely affected by psychiatric disorders (n = 76, 14.0% women vs. n = 21, 6.8% men; p = 0.0015). Men were mainly assisted by their wives (n = 207, 66.6%), women mainly by their daughters (n = 243, 44.7%) and only in a minority of cases by their husbands (n = 92, 16.9%). Women less frequently cohabited with their caregivers than men (n = 233, 43.1% vs. n = 240, 77.9%, p < 0.0001), and received less daily time of caregiving (mean (± SD): 10.0 ± 7.2 vs. 15.2 ± 8.2; p < 0.0001). No gender differences were highlighted in compliance to treatment and caregiver satisfaction, while gender differences in caregiving were found at disadvantage of women affected by more severe cognitive and psychiatric conditions. [ABSTRACT FROM AUTHOR]

Published
2023
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48. Morphological Neural Computation Restores Discrimination of Naturalistic Textures in Trans-radial Amputees

Author

Mazzoni, Alberto, Oddo, Calogero M., Valle, Giacomo, Camboni, Domenico, Strauss, Ivo, Barbaro, Massimo, Barabino, Gianluca, Puddu, Roberto, Carboni, Caterina, Bisoni, Lorenzo, Carpaneto, Jacopo, Vecchio, Fabrizio, Petrini, Francesco M., Romeni, Simone, Czimmermann, Tamas, Massari, Luca, di Iorio, Riccardo, Miraglia, Francesca, Granata, Giuseppe, Pani, Danilo, Stieglitz, Thomas, Raffo, Luigi, Rossini, Paolo M., and Micera, Silvestro

Published
2020
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50. Association between CSF biomarkers, hippocampal volume and cognitive function in patients with amnestic mild cognitive impairment (MCI)

Author

Nathan, Pradeep J., Lim, Yen Ying, Abbott, Rosemary, Galluzzi, Samantha, Marizzoni, Moira, Babiloni, Claudio, Albani, Diego, Bartres-Faz, David, Didic, Mira, Farotti, Lucia, Parnetti, Lucilla, Salvadori, Nicola, Müller, Bernhard W., Forloni, Gianluigi, Girtler, Nicola, Hensch, Tilman, Jovicich, Jorge, Leeuwis, Annebet, Marra, Camillo, Molinuevo, José Luis, Nobili, Flavio, Pariente, Jeremie, Payoux, Pierre, Ranjeva, Jean-Philippe, Rolandi, Elena, Rossini, Paolo Maria, Schönknecht, Peter, Soricelli, Andrea, Tsolaki, Magda, Visser, Pieter Jelle, Wiltfang, Jens, Richardson, Jill C., Bordet, Régis, Blin, Olivier, and Frisoni, Giovanni B.

Published
2017
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