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8 results on '"Sbianchi, Giulia"'

1. Prognostic value of a new clinically-based classification system in patients with CMML undergoing allogeneic HCT: a retrospective analysis of the EBMT-CMWP

Author

Onida, Francesco, Sbianchi, Giulia, Radujkovic, Aleksandar, Sockel, Katja, Kröger, Nicolaus, Sierra, Jorge, Socié, Gerard, Cornelissen, Jan, Poiré, Xavier, Raida, Luděk, Bourhis, Jean Henri, Finke, Jürgen, Passweg, Jakob, Salmenniemi, Urpu, Schouten, Harry C., Beguin, Yves, Martin, Sonja, Deconinck, Eric, Ganser, Arnold, Zver, Samo, Lioure, Bruno, Rohini, Radia, Koster, Linda, Hayden, Patrick, Iacobelli, Simona, Robin, Marie, and Yakoub-Agha, Ibrahim

Published
2022
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2. Impact of prior JAK-inhibitor therapy with ruxolitinib on outcome after allogeneic hematopoietic stem cell transplantation for myelofibrosis: a study of the CMWP of EBMT

Author

Kröger, Nicolaus, Sbianchi, Giulia, Sirait, Tiarlan, Wolschke, Christine, Beelen, Dietrich, Passweg, Jakob, Robin, Marie, Vrhovac, Radovan, Helbig, Grzegorz, Sockel, Katja, Conneally, Eibhlin, Rubio, Marie Thérèse, Beguin, Yves, Finke, Jürgen, Bernasconi, Paolo, Morozova, Elena, Clausen, Johannes, von dem Borne, Peter, Schaap, Nicolaas, Schroyens, Wilfried, Patriarca, Francesca, Di Renzo, Nicola, Yeğin, Zeynep Arzu, Hayden, Patrick, McLornan, Donal, and Yakoub-Agha, Ibrahim

Published
2021
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3. Incidence of Second Primary Malignancies after Autologous Transplantation for Multiple Myeloma in the Era of Novel Agents

Author

Sahebi, Firoozeh, Iacobelli, Simona, Sbianchi, Giulia, Koster, Linda, Blaise, Didier, Reményi, Péter, Russell, Nigel H., Ljungman, Per, Kobbe, Guido, Apperley, Jane, Trneny, Marek, Krejci, Marta, Wiktor-Jedrzejczak, Wieslaw, Sanchez, James F., Schaap, Nicolaas, Isaksson, Cecilia, Lenhoff, Stig, Browne, Paul, Scheid, Christof, Wilson, Keith M.O., Yakoub-Agha, Ibrahim, Muñiz, Soledad González, Schönland, Stefan, Morris, Curly, Garderet, Laurent, and Kröger, Nicolaus

Published
2018
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4. Allogeneic hematopoietic cell transplantation in patients with chronic phase chronic myeloid leukemia in the era of third generation tyrosine kinase inhibitors: A retrospective study by the chronic malignancies working party of the EBMT.

Author

Chalandon, Yves, Sbianchi, Giulia, Gras, Luuk, Koster, Linda, Apperley, Jane, Byrne, Jenny, Salmenniemi, Urpu, Sengeloev, Henrik, Aljurf, Mahmoud, Helbig, Grzegorz, Kinsella, Francesca, Choi, Goda, Reményi, Péter, Snowden, John A., Robin, Marie, Lenhoff, Stig, Mielke, Stephan, Passweg, Jakob, Broers, Annoek E. C., and Kröger, Nicolaus

Published
2023
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5. Complications of Autologous Stem Cell Transplantation in Multiple Myeloma: Results from the CALM Study.

Author

Waszczuk-Gajda, Anna, Penack, Olaf, Sbianchi, Giulia, Koster, Linda, Blaise, Didier, Reményi, Péter, Russell, Nigel, Ljungman, Per, Trneny, Marek, Mayer, Jiri, Iacobelli, Simona, Kobbe, Guido, Scheid, Christof, Apperley, Jane, Touzeau, Cyrille, Lenhoff, Stig, Jantunen, Esa, Anagnostopoulos, Achilles, Paris, Laura, and Browne, Paul

Subjects
STEM cell transplantation, MULTIPLE myeloma, AUTOGRAFTS, MONOCLONAL gammopathies, TREATMENT effectiveness, BACTERIAL diseases
Abstract

Background: The main goal of this post hoc analysis of the Collaboration to Collect Autologous Transplant Outcomes in Lymphoma and Myeloma (CALM) study was to evaluate the rate of short- and long-term infectious and non-infectious complications occurring after ASCT in patients with multiple myeloma (MM). Methods: The analysis included all patients with MM from the CALM study who underwent ≥1 ASCT. The primary endpoint of the analysis was to determine the rate of infectious and non-infectious complications after ASCT and to compare them in three time periods: 0–100 days, 101 days–1 year, and >1 year after the first transplant. Results: The analysis included a total of 3552 patients followed up for a median of 56.7 months (range 0.4–108.1). Complication rates decreased with the time from ASCT with 24.85 cases per 100 patient-years from day 0 to 100 days after the transplant, and <2.31 cases per 100 patient-years from the 101st day. At 100 days after ASC T, 45.7% of patients had complications, with infectious events being twice as frequent as non-infectious complications. Bacterial infections (6.5 cases per 100 patient-years, 95% CI: 6.1–7.0) and gastrointestinal complications (4.7 cases per 100 patient-years, 95% CI: 4.3–5.1) were the most common early events. The pattern of complications changed with time from ASCT. The presence of complications after ASCT was not associated with overall survival. Conclusions: Our data provide a solid basis for comparing ASCT-related complications to those caused by emerging treatments in multiple myeloma, such as CAR T-cell therapy and other immunotherapies. [ABSTRACT FROM AUTHOR]

Published
2022
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6. IgD Subtype But Not IgM or Non-Secretory Is a Prognostic Marker for Poor Survival Following Autologous Hematopoietic Cell Transplantation in Multiple Myeloma. Results From the EBMT CALM (Collaboration to Collect Autologous Transplant Outcomes in Lymphomas and Myeloma) Study

Author

Lawless, Sarah, Sbianchi, Giulia, Morris, Curly, Iacobelli, Simona, Bosman, Paul, Blaise, Didier, Reményi, Péter, Byrne, J. L., Mayer, Jiri, Apperley, Jane, Lund, Johan, Kobbe, Guido, Schaap, Nicolaas, Isaksson, Cecilia, Lenhoff, Stig, Basak, Grzegorz, Touzeau, Cyrille, Wilson, Keith M.O., González Muñiz, Soledad, and Scheid, Christof

Published
2021
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7. Prognostic impact of early‐versus‐late responses to different induction regimens in patients with myeloma undergoing autologous hematopoietic cell transplantation: Results from the CALM study by the CMWP of the EBMT.

Author

Garderet, Laurent, Sbianchi, Giulia, Iacobelli, Simona, Blaise, Didier, Byrne, Jenny L., Remenyi, Peter, Apperley, Jane F., Touzeau, Cyrille, Isaksson, Cecilia, Browne, Paul, Mayer, Jiri, Lenhoff, Stig, Gonzalez Muniz, Soledad, Parody Porras, Rocio, Basak, Grzegorz, Poire, Xavier, Trneny, Marek, Nagler, Arnon, Michieli, Mariagrazia, and Tanase, Alina

Subjects
*HEMATOPOIETIC stem cell transplantation, *AUTOTRANSPLANTATION, *STEM cells, *MULTIPLE myeloma, *TREATMENT effectiveness
Abstract

Background: In autologous stem cell transplant (ASCT)‐eligible myeloma patients, prolonged induction does not necessarily improve the depth of response. Method: We analyzed 1222 ASCT patients who were classified based on (a) the interval between induction and stem cell collection, (b) the type of induction regimen: BID (Bortezomib, IMiDs, and Dexamethasone), Bortezomib‐based, or CTD (Cyclophosphamide, Thalidomide, and Dexamethasone), and (c) the time to best response (Early ie, best response within 4 or 5 months, depending on the regimen vs Late; Good ie, VGPR or better vs Poor). Results: The length of induction treatment required to achieve a Good response did not affect PFS (P =.65) or OS (P =.61) post‐ASCT. The three types of regimen resulted in similar outcomes: median PFS 31, 27.7 and 30.8 months (P =.31), and median OS 81.7, 92.7, and 77.4 months, respectively (P =.83). On multivariate analysis, neither the type nor the duration of the induction regimen affected OS and PFS, except for Early Good Responders who had a better PFS compared to Early Poor Responders (HR = 1.21, P‐value =.02). However, achieving a Good response at induction was associated with a better response (≥VGPR) post‐transplant. Conclusion: The kinetics of response did not affect outcomes. [ABSTRACT FROM AUTHOR]

Published
2021
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8. Impact of T‐cell depletion strategies on outcomes following hematopoietic stem cell transplantation for idiopathic aplastic anemia: A study on behalf of the European blood and marrow transplant severe aplastic anemia working party.

Author

Samarasinghe, Sujith, Clesham, Katherine, Iacobelli, Simona, Sbianchi, Giulia, Knol, Cora, Hamladji, Rose‐Marie, Socié, Gerard, Aljurf, Mahmoud, Koh, Mickey, Sengeloev, Henrik, Dalle, Jean‐Hugues, Robinson, Stephen, Van Lint, Maria Teresa, Halkes, Constantijn J. M., Beelen, Dietrich, Mufti, Ghulam J., Snowden, John, Blaise, Didier, de Latour, Regis Peffault, and Marsh, Judith

Published
2019
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