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460 results on '"Takeda, Taizo"'

2. Expression of AQP-10, -11 and -12 in the rat stria vascularis.

Author

Ichikawa, Rie, Takeda, Taizo, Kakigi, Akinobu, Ito, Hiroaki, Kobayashi, Taisuke, and Hyodo, Masamitsu

Subjects
*GENE expression, *RATS, *IMMUNOHISTOCHEMISTRY, *ANIMAL experimentation, *MOLECULAR biology, *MEMBRANE proteins, *COCHLEA, *CELLS
Abstract

Water homeostasis is essential for inner ear function. Several aquaporins (AQPs), which are water transport proteins in the cell or plasma membrane, have been reported in the lateral wall of the rat inner ear (cochlea). However, the presence of AQP-10, -11 and -12 has not been reported in the rat stria vascularis (SV) to date. We have aimed to clarify the expression of AQP-10, -11 and -12 in the cochlea lateral wall. Using Wistar rats, we examined the expression of AQP-10, -11 and -12 in the cochlea lateral wall using molecular approaches and immunohistochemistry. AQP-11 was molecular biologically expressed, but the expression of AQP-10 and -12 was not observed. Immunohistochemically, AQP-11 was diffusely localized in the basal cells and marginal cells of the rat SV but was not expressed at the apical site of marginal cells with double staining. The expression of AQP-10 and -12 was not observed. Only AQP-11 was expressed in the basal cells and marginal cells, but it was not expressed at the apical site of marginal cells. Based on this study, AQP-11 may not have an important role in water flux between the perilymph and endolymph. [ABSTRACT FROM AUTHOR]

Published
2024
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28. Syncope as a Sign of Occult Malignant Recurrence in the Retropharyngeal and Parapharyngeal Space: CT and MR Imaging Findings in Four Cases

Author

Nakahira, Mitsuhiko, Nakatani, Hiroaki, and Takeda, Taizo

Subjects
Adult, Male, Pharyngeal Neoplasms, Middle Aged, Magnetic Resonance Imaging, Syncope, Carotid Arteries, Head and Neck Neoplasms, Recurrence, Carcinoma, Squamous Cell, Humans, Pharynx, Tomography, X-Ray Computed, Head and Neck, Aged
Abstract

Summary: Although rare, syncope may result from metastasis to the retropharyngeal or parapharyngeal space and involve or invade the glossopharyngeal nerve or internal carotid artery. We report the CT and MR imaging findings in four patients with syncope that preceded the diagnosis of recurrent squamous cell carcinoma in the pericarotid region. These findings suggest that recurrent carcinoma should be ruled out when a patient with head and neck malignancy and syncope is postoperatively examined.

Published
2002

29. Left Vocal Cord Paralysis Associated with Long-standing Patent Ductus Arteriosus

Author

Nakahira, Mitsuhiko, Nakatani, Hiroaki, and Takeda, Taizo

Subjects
congenital, hereditary, and neonatal diseases and abnormalities, Recurrent Laryngeal Nerve, Nerve Compression Syndromes, Pulmonary Artery, embryonic structures, cardiovascular system, Disease Progression, Humans, Female, cardiovascular diseases, Tomography, X-Ray Computed, Ductus Arteriosus, Patent, Vocal Cord Paralysis, Head and Neck, Aged
Abstract

Summary: Left vocal cord paralysis in association with patent ductus arteriosus is unusual. We report a patient with long-standing patent ductus arteriosus (PDA) in whom CT studies obtained before and after paralysis developed showed an interval increase in size of the pulmonary trunk. The pathogenesis of left vocal cord paralysis in association with long-standing PDA is discussed.

Published
2001

30. Protective effect of edaravone against endolymphatic hydrops

Author

Takumida, Masaya, Takeda, Taizo, Takeda, Setsuko, Kakigi, Akinori, Nakatani, Hiroaki, Anniko, Matti, Takumida, Masaya, Takeda, Taizo, Takeda, Setsuko, Kakigi, Akinori, Nakatani, Hiroaki, and Anniko, Matti

Abstract

CONCLUSION: Our findings suggest that edaravone prevented the production of reactive oxygen species (ROS). Edaravone also delayed the formation of endolymphatic hydrops in guinea pigs, but had no effect on endolymphatic hydrops. OBJECTIVE: To analyse the protective effect of a free radical scavenger, edaravone, on endolymphatic hydrops. MATERIALS AND METHODS: Guinea pigs were subjected to surgical obliteration of the endolymphatic duct (ED). For the detection of ROS, group 1 received intraperitoneal injections of edaravone (3 mg/kg/day) for 2 days, group 2 received edaravone for 2 weeks, group 3 saline for 2 days, and group 4 saline for 2 weeks. ROS production by the organ of Corti and stria vascularis was examined by using dihydrotetramethylrosamine. For the morphological analysis, guinea pigs were divided into five groups, i.e. 2 or 4 weeks after ED obliteration, 2 weeks with edaravone, first or last 2 weeks with edaravone and sacrificed 4 weeks after ED obliteration. Increases in the ratios of the cross-sectional area of scala media were analysed quantitatively to assess the degree of endolymphatic hydrops among the above-mentioned five groups of the hydropic cochlea. RESULTS: ROS was detected both in the organ of Corti and in the lateral wall of cochleae 2 days after ED obliteration. Edaravone prevented the production of ROS and also attenuated the formation of endolymphatic hydrops in the acute hydrops group.

Published
2007
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31. Méniéres disease : a long-term follow-up study of bilateral hearing levels

Author

Takumida, Masaya, Kakigi, Akinobu, Takeda, Taizo, Anniko, Matti, Takumida, Masaya, Kakigi, Akinobu, Takeda, Taizo, and Anniko, Matti

Abstract

CONCLUSION: It is suggested that a holistic factor - such as psychological stress--is involved in Menière's disease (MD) and that the pathological changes in MD may be a result not only of endolymphatic hydrops but also of disorders affecting the entire cochlea. PATIENTS AND METHODS: Changes in the hearing of 51 patients with unilateral MD were investigated to ascertain the correlation between changes in hearing loss (a) in the affected ear vs the contralateral ear and (b) at low frequencies vs high frequencies. RESULTS: About half of the MD patients showed a significant positive correlation between the hearing level in the affected ear and that in the contralateral ear and also between the average hearing level at lower frequencies and that at 8 kHz. These tendencies were more pronounced in patients with severe fluctuation of hearing and/or severe hearing loss.

Published
2006
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46. Changes in the characteristics of definite Meniere's disease over time in Japan: a long-term survey by the Peripheral Vestibular Disorder Research Committee of Japan, formerly the Meniere's Disease Research Committee of Japan

Author

Shojaku, Hideo, primary, Watanabe, Yukio, additional, Yagi, Toshiaki, additional, Takahashi, Masahiro, additional, Takeda, Taizo, additional, Ikezono, Tetsuo, additional, Ito, Juichi, additional, Kubo, Takeshi, additional, Suzuki, Mamoru, additional, Takumida, Masaya, additional, Takeda, Noriaki, additional, Furuya, Nobuhiko, additional, and Yamashita, Hiroshi, additional

Published
2009
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