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1,105 results on '"Xie, Lili"'

20. A study of innovative strategies for teaching English to college students based on tiered probit

Author

Xie Lili

Subjects
stratified statistical model, autoregressive model, probit model, university english language teaching, egp+esp+eic, 97c50, Mathematics, QA1-939
Abstract

This paper analyzes the current situation of university English teaching and constructs a trinity of EGP+ESP+EIC multiple teaching innovation systems for university English based on the principles of English teaching innovation. In order to analyze this innovative teaching system of English, a stratified statistical model and a spatial autoregressive model are combined, and four ordinal stratified spatial autoregressive Probit models are innovatively constructed to model data where the dependent variable is ordinal, and there is a spatial dependency situation with a stratified structure. The analysis shows that in the process of continuous innovation of English teaching mode, the number of people who are dissatisfied with English teaching decreases by 30%, the number of people who are very satisfied increases by 35%, and the number of people who are very satisfied accounts for 42.5% of the total number of people and 90% of the total number of people who are satisfied in the final stage of innovation of English teaching in university. The English teaching innovation strategy for university students based on this study is feasible.

Published
2024
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21. Micturition-Induced Reflex Epilepsy

Author

Li, Xia, Wang, Rui, Song, Wenchun, and Xie, Lili

Subjects
Seizures (Medicine), Levetiracetam, Epilepsy, Health
Abstract

Byline: Xia. Li, Rui. Wang, Wenchun. Song, Lili. Xie Sir, Micturition-induced epilepsy is a type of epilepsy characterized by seizures triggered by specific stimuli, including not only micturition but also [...]

Published
2023

39. D-methionine eradicates Porphyromonas gingivalis biofilms by suppressing the cyclic di-GMP level

Author

XIE Lili, ZHANG Huiyan, WANG Zixuan, LI Birong, LI Zhen, and MENG Weiyan

Subjects
biofilm，, porphyromonas gingivalis，, d-methionine，, cyclic diguanosine monophosphate，, periodontitis，, peri-implantitis，, exopolysaccharide，, cell membrane，, high performance liquid chromatography，, Medicine
Abstract

Objective To investigate the mechanisms by which D-methionine (D-Met) eradicates Porphyromonas gingivalis biofilms by suppressing cyclic dimeric GMP (c-di-GMP) levels. Methods Cell viability, minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were measured to determine the effective concentrations of D-Met, which were subsequently used in the following experiments. During the P. gingivalis biofilm formation inhibition experiment and the mature biofilm disassembly experiment, biofilm biomass, exopolysaccharide (EPS), biofilm morphology, integrity of the cell membrane, and the level of c-di-GMP were determined. Results D-Met < 40 mmol/L was biocompatible. During the biofilm formation inhibition and mature biofilm disassembly experiments, D-Met ≥ 20 mmol/L decreased the biofilm biomass and the production of EPS. SEM analysis showed that the extracellular matrix and bacterial density were drastically reduced by D-Met ≥ 20 mmol/L. TEM detection showed that 35 mmol/L D-Met ruptured the cell membrane during biofilm formation and increased the permeability of the cell membrane in the disassembly phase of mature biofilms. C-di-GMP levels decreased with increasing concentrations of D-Met in a concentration-dependent manner. Conclusion D-Met ≥ 20 mmol/L could eradicate P. gingivalis biofilms by suppressing c-di-GMP levels.

Published
2022
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