160 results on '"van Delft, Joost"'
Search Results
2. Integrating multiple omics to unravel mechanisms of Cyclosporin A induced hepatotoxicity in vitro
3. Interindividual variation in response to xenobiotic exposure established in precision-cut human liver slices
4. A review on ochratoxin A transcriptomic studies
5. New insights into BaP-induced toxicity: role of major metabolites in transcriptomics and contribution to hepatocarcinogenesis
6. Interindividual variation in gene expression responses and metabolite formation in acetaminophen-exposed primary human hepatocytes
7. Cyclosporine A treated in vitro models induce cholestasis response through comparison of phenotype-directed gene expression analysis of in vivo Cyclosporine A-induced cholestasis
8. Proteomics in the search for mechanisms and biomarkers of drug-induced hepatotoxicity
9. Transcriptome Analysis in Peripheral Blood of Humans Exposed to Environmental Carcinogens: A Promising New Biomarker in Environmental Health Studies
10. Effect of Trichostatin A on miRNA expression in cultures of primary rat hepatocytes
11. Biotransformation pathway maps in WikiPathways enable direct visualization of drug metabolism related expression changes
12. A toxicogenomics-based parallelogram approach to evaluate the relevance of coumarin-induced responses in primary human hepatocytes in vitro for humans in vivo
13. Oxidative stress induced by potassium bromate exposure results in altered tight junction protein expression in renal proximal tubule cells
14. Comparison of genotoxicant-modified transcriptomic responses in conventional and epigenetically stabilized primary rat hepatocytes with in vivo rat liver data
15. Comparison of hepatocarcinogen-induced gene expression profiles in conventional primary rat hepatocytes with in vivo rat liver
16. Mechanisms of colorectal and lung cancer prevention by vegetables: a genomic approach
17. Characterisation of cisplatin-induced transcriptomics responses in primary mouse hepatocytes, HepG2 cells and mouse embryonic stem cells shows conservation of regulating transcription factor networks
18. Vegetables affect the expression of genes involved in carcinogenic and anticarcinogenic processes in the lungs of female C57BI/6 mice
19. Vegetables affect the expression of genes involved in anticarcinogenic processes in the colonic mucosa of C57BI/6 female mice
20. Gender-specific transcriptomic response to environmental exposure in flemish adults
21. Transcriptomic responses generated by hepatocarcinogens in a battery of liver-based in vitro models
22. RNA-Seq Provides New Insights in the Transcriptome Responses Induced by the Carcinogen Benzo[a]pyrene
23. Performance of in vitro γH2AX assay in HepG2 cells to predict in vivo genotoxicity
24. SFTG international collaborative study on in vitro micronucleus test: II. Using human lymphocytes
25. ʼOmics analysis of low dose acetaminophen intake demonstrates novel response pathways in humans
26. Human Embryonic Stem Cell Derived Hepatocyte-Like Cells as a Tool for In Vitro Hazard Assessment of Chemical Carcinogenicity
27. Deregulation of Cancer-Related Pathways in Primary Hepatocytes Derived from DNA Repair-Deficient Xpa−/−p53+/− Mice upon Exposure to Benzo[a]pyrene
28. Response to Pathophysiological Relevance of Proteomics Investigations of Drug-Induced Hepatotoxicity in HepG2 Cells
29. Alternative (non-animal) methods for cosmetics testing: current status and future prospects—2010
30. Proteomics Investigations of Drug-Induced Hepatotoxicity in HepG2 Cells
31. Concentration-dependent gene expression responses to flusilazole in embryonic stem cell differentiation cultures
32. Application of toxicogenomics in hepatic systems toxicology for risk assessment: Acetaminophen as a case study
33. Evaluation of Developmental Toxicant Identification Using Gene Expression Profiling in Embryonic Stem Cell Differentiation Cultures
34. Transcriptomic Profile Indicative of Immunotoxic Exposure
35. Time Series Analysis of Benzo[A]Pyrene-Induced Transcriptome Changes Suggests That a Network of Transcription Factors Regulates the Effects on Functional Gene Sets
36. Monitoring Developmental Toxicity in the Embryonic Stem Cell Test Using Differential Gene Expression of Differentiation-Related Genes
37. Comparison of HepG2 and HepaRG by Whole-Genome Gene Expression Analysis for the Purpose of Chemical Hazard Identification
38. Global Gene Expression Analysis Reveals Differences in Cellular Responses to Hydroxyl- and Superoxide Anion Radical–Induced Oxidative Stress in Caco-2 Cells
39. Discrimination for Genotoxic and Nongenotoxic Carcinogens by Gene Expression Profiling in Primary Mouse Hepatocytes Improves with Exposure Time
40. Potential role of cytochrome P450-1B1 in the metabolic activation of 4-aminobiphenyl in humans
41. Parallelogram Approach Using Rat-Human In Vitro and Rat In Vivo Toxicogenomics Predicts Acetaminophen-induced Hepatotoxicity in Humans
42. Interactions between polycyclic aromatic hydrocarbons in binary mixtures: Effects on gene expression and DNA adduct formation in precision-cut rat liver slices
43. Gene expression changes induced by ochratoxin A in renal and hepatic tissues of male F344 rat after oral repeated administration
44. Genomic analysis suggests higher susceptibility of children to air pollution
45. Binary PAH mixtures cause additive or antagonistic effects on gene expression but synergistic effects on DNA adduct formation
46. In vitro gene expression data supporting a DNA non-reactive genotoxic mechanism for ochratoxin A
47. Cigarette smoke-induced differential gene expression in blood cells from monozygotic twin pairs
48. Modulation of gene expression and DNA-adduct formation in precision-cut liver slices exposed to polycyclic aromatic hydrocarbons of different carcinogenic potency
49. Modulation of gene expression and DNA adduct formation in HepG2 cells by polycyclic aromatic hydrocarbons with different carcinogenic potencies
50. Differential Gene Expression in Human Peripheral Blood Mononuclear Cells Induced by Cigarette Smoke and Its Constituents
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