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The article analyzes international acts adopted by the United Nations, the Council of Europe, and European Unions in the field of combating discrimination and anti-discrimination legislation of Ukraine. The article considers the law of Ukraine «Оn the principles of preventing and countering discrimination in Ukraine», which contains a generalizing concept of «discrimination», defines forms of discrimination and lists protected features. It is proposed to fix in Article 1 of this law the definition of the term «protected feat ures». Scientific works of V. Iskovich and V. Galan in the field of studying new types of discrimination and protected features are studied. It is established that the protected characteristics that are enshrined in international acts include: race, skin color; gender; religious views; ethnic origin; language; marital status; political and other views; environmental and other status; place of birth; age; health status; birth of a child; status; availability of property; any form of social segregation; genetic inheritance; economic activity and profession. The UN Convention on the Elimination of All Forms of Discrimination against Women, the International Convention on the Elimination of All Forms of Racial Discrimination, the Convention on the Rights of Persons with Disabilities and its Optional Protocol are studied in more detail. Definitions of the following concepts are considered: «discrimination on the basis of race», «discrimination on the basis of gender», «discrimination on the basis of age», «discrimination on the basis of disability». Special attention is paid to the implementation of the principle of equal rights of women and men in Ukraine. In order to implement UN Security Council Resolution 1325 «Women, peace, security» in 2020, the Cabinet of Ministers of Ukraine approved the National Action Plan for the period up to 2025. In 2022, the Ministry of social policy prepared a draft state strategy for ensuring equal rights and opportunities for women and men until 2030 and an action plan f or 2022 2024 ם of Ukraine. It is established that the European Court of Human Rights is of great importance for the interpretation of the concept of «protected attribute». The court practice of the ECHR actually expands the list of protected features, which should be taken into account when improving the national anti-discrimination legislation. [ABSTRACT FROM AUTHOR]

Background. The incidence of metabolic dysfunction-associated steatotic liver disease (MASLD) is increasing along with the increasing prevalence of obesity. There are close relationships between these two pathologies due to the functioning of adipose tissue as an endocrine organ with a complex influence on various metabolic processes. It is known that premenopausal women are less prone to fatty liver disease than men. The aim was to study the influence of gender, body mass index (BMI) and age on sonographic indicators and the degree of liver steatosis in patients with metabolic dysfunction-associated steatotic liver disease. Materials and methods. Ninety-two patients with MASLD were included in the study, 48 women and 44 men. Inclusion criterion was metabolic dysfunction-associated steatotic liver disease, exclusion criteria were any non-metabolic factors of chronic diffuse liver disease. Patients were divided into groups by gender and age. Women were divided by age according to the presence and absence of menopause, men were divided into groups below and above 45 years - the conventional age of the beginning of the decline in gonadotropic function. The analysis of structural changes of the liver, namely the assessment of the size, contours, structure, echogenicity, and visualization of blood vessels in the B-mode was carried out with the help of ultrasound examination on Toshiba Xario 660 (Japan). The degree of steatosis was assessed by the controlled attenuation parameter. Results. In men, the right, left and caudate liver lobes were significantly larger (p < 0.05) than in women, which is due to the higher weight of men in the absence of a difference in the BMI. There was no significant difference between men and women in degree of steatosis (p > 0.05). A moderate positive correlation (r = 0.63) was found between BMI and the controlled attenuation parameter; in women, there was no connection between these indicators. Analysis of correlations in women of different ages, divided by the presence of menopause, found that before menopause, there was no dependence of steatosis indicators on BMI, while with the onset of menopause, the coefficient of correlation between these indicators was 0.39 (p < 0.02). Conclusions. No significant difference was found between the frequency of various degrees of steatosis in MASLD according to the controlled attenuation parameter in men and women. There was a dependence of the severity of liver steatosis on the BMI in men, the dependence of steatosis on the body mass index in women was manifested starting from the menopause period, which suggests the protective role of female sex hormones. [ABSTRACT FROM AUTHOR]

Nowadays, knowledge about the causal relationships between concomitant chronic diseases and the course of coronavirus infection (COVID-19) can make a huge contribution to saving the lives of patients. Determining the impact of concomitant pathology on the severity of the course of COVID-19 will contribute to the identification and assessment of the risk of deterioration of the condition, as well as the implementation of preventive measures in high-risk individuals (vaccination). The aim of the work was to assess the influence of age and sex on the presence of comorbid pathology and the course of the disease in patients who were hospitalized with community-acquired viral pneumonia associated with COVID-19. We carried out a retrospective analysis of the case histories of 260 patients with community-acquired pneumonia associated with coronavirus disease, who were treated in the therapeutic departments of the Covid Center of ME “Dnipropetrovsk regional clinical hospital named after Mechnikov” DRC in 2020-2021. (September-December 2020, January- December 2021), single-center study. All patients included in the analysis underwent general clinical and laboratory methods of research regulated by national recommendations for the management of patients with COVID-19, PCR tests (polymerase chain reaction) for verification of coronavirus disease, CT(computed tomography)/radiography of the lungs. Comorbidity was assessed as the development of the disease before the onset / verification of coronavirus disease according to a patient survey recorded in medical records. One or more comorbid conditions were recorded in 195 (75%) patients. Multimorbidity was recorded in 111 (56.9%) patients from the total number of patients with COVID-19 and comorbid pathology. Analyzing the influence of gender in patients with comorbid pathology, men were significantly more likely to have coronary artery disease (CAD) (p=0.04) and chronic obstructive pulmonary disease (COPD) (p=0.04). A significant difference in age among hospitalized patients with a diagnosis of COVID-19 was revealed, depending on sex (p<0.001). So at the age of up to 65 years, male patients predominated (60.4%), over the age of 65 years – women (68.9%). There was no significant difference in the frequency of occurrence of moderate severity and severe course of the disease of COVID-19, depending on age and sex. At the age of over 65, the presence of type 2 diabetes (p<0.001), hypertension (p<0.001), coronary artery disease (p<0.001) and COPD (p<0.001) was significantly more common. [ABSTRACT FROM AUTHOR]

The purpose of the paper is to investigate children's burials of the Middle Sarmatian period on the territory of the Northern Black Sea region. Try to determine the gender of the buried children on the basis of the burial inventory in comparison with the adults of the respective burial grounds. Supplement archaeological materials with the help of ethnographic information. Scientific novelty. The article reconstructs the life of children of Middle Sarmatian society based on archaeological, ethnographic and anthropological data. The study of children's burials on the materials of grave sites from the Northern Black Sea region has not been conducted yet. Conclusions. Peculiarities of children's society are considered depending on their age and gender. Babies did not have their own individual property they were buried only in burials together with adult women. At the age of 1-3 years, little Sarmatians stopped feeding with mother's milk. Sarmatians perceived children of this age as separate individuals and buried them in separate burials. Children already have their personal belongings, including weapons. However, it was not possible to trace any gender orientation of these things, according to the available sources, at the moment. Sarmatians already divided children between the ages of 4 and 7 by gender. Judging by the peaks of mortality, it was at this age that Sarmatian children were most at risk. In this group, it was possible to determine that most of the dead children were female. Evidence of children's participation in domestic work was also found. At the age of 8-12, the education of Sarmatian boys was completely transferred to the hands of male society. Meanwhile, girls were actively taught housekeeping, preparing for future marriage. At the age of 12 to 16, Sarmatian teenagers entered adulthood as full-fledged members of both male and female society. Girls from wealthy families, at this age, could have a dowry, with which, in the event of their death, they were buried. Funding. The research was implemented thanks to funding from project Documenting, Recording and Saving Ukrainian Archaeological Heritage by German Archaeological Institute (Deutschen Archäologischen Institut). [ABSTRACT FROM AUTHOR]

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Ukraine is going through difficult times of a prolonged demographic crisis. The objective: to study and analyze the age-related birth rates in the Transcarpathian region of Ukraine and analyze the birth rates among women who are not in a registered marriage. Materials and methods. In the course of the study, official data from sectoral statistical reporting for 2000–2021 were used in the cross-section of the administrative territories of Transcarpathian region. The research was conducted in four stages. Bibliosemantic and medical-statistical methods and the method of structural logical analysis are used. Results. It was established that the total birth rate in Transcarpathian region during the study period decreased by 16.4% and in 2021 it was 1.534. At the same time, a decrease in the birth rate was registered in the age groups of women from 15 to 39 years, and among women in the age category 40–49 years, a tendency to increase the birth rate was revealed. In the age group of 15–19 years the birth rate decreased by 1.31 times and amounted to 39.6; in the age group of 20–24 years, the birth rate decreased by 1.33 times and amounted to 133.3; in the age group of 25–29 years the birth rate decreased by 1.34 times and amounted to 88.9; in the age group of 30–34 years the birth rate decreased by 1.09 times and amounted to 51.3; in the age group of 35–39 years the birth rate decreased by 1.08 times and amounted to 21.0; in the age group of 40–44 years the birth rate increased by 1.13 times and was 5.2; in the age group of 45–49 years, the birth rate increased by 3.0 times and was 0.3. The rate of children who were born in mothers who were not in a registered marriage increased by 1.8 times in 2021 and accounted for 24.3% of the total number of live births. A uniform growth of the specified indicator was registered both in cities and in rural areas. Conclusions. The results of the study provide a basis for ascertaining the negative dynamics of the birth rate in Transcarpathian region, which will further intensify due to the consequences of the war against Russian aggression. [ABSTRACT FROM AUTHOR]

Дос лідження проведено у продовж 2020–2021 рр. на вівцематках (515 гол.) різного віку харків-ського внутрішньо-породного типу породи прекос(ХТП)та їх потомстві в умовах племінного заводу «Державного підприємства дослідноггосподарства «ГонтарівкаІнституту тваринництва НААН. Дослідженнями установлено, щоза 45 діб, у продовж яких застосовувалось штучне осіменін-ня,запліднюваність овець(ЗП) , розрахована за результатами їх ягнінняв середньому склала 91,8 %. Найвищим показником характеризувалися вівці, які малитретє ягніння 97,3%. За результатами 4-6 ягнінь відзначалася відносно стабільна висока запліднюваності маток – 93,4-95,3 %. Значні відхилен-ня у бік зниження цього показника спостерігалися у вівцематок, використаних для відтворення по першому та другому року та, особливо, у тварин з 7 та 8 і більше ягнінням.Дисперсійним аналізом, було встановлено, що фактор віку вівцематок високовірогідно (р< 0,01) пов’язаний з їх запліднювані-стю, а сила його впливу ŋх 2 складає0,491. Фактор окремих баранів-плідників є також впливовим щодо їх (ЗП). Мінливість, обумовлена впливом цього фактора, варіювала в межах від 87 до 95,1 %.Різна (ЗП) вівцематок, обумовлена їх віком, відповідним чином позначилась на показниках їх багатоплідності (БП), розрахованих на 100 голів, що осіменялися.Цей показник у вівцематок за пер-шим-п’ятим ягнінням знаходився у межах від 113 до 150 ягнят. При цьому простежується чітка тенденція щодо його зростання у зв’язку зі збільшенням кількості репродуктивних років. Разом з цим, ця тенденція не носить прямолінійної залежності та дійсна для тварин з 1-6 ягніннями. Вівце-матки з 7 та 8 і більше ягніннями доволі різко погіршують свою репродуктивну здатність

The relative clause attachment preferences of female Persian learners of English were investigated regarding their age and modes of presentation (online/offline and holistic/segmented). 50 female native speakers of Persian ranging in age from 15 to 25 participated in the study. The instruments used in the present research included two tests of ambiguous sentences: 1) a grammaticality judgment test, and 2) the main test which was presented in three separate forms: a) offline, b) online complete presentation (timed) and c) online segment by segment sentence (self-paced). This study used the method employed by Kim and Christianson (2013) for determining the attachment preferences of the participants. The results revealed that the participants' age affected the attachment preferences significantly in that adolescents had a clear determiner phrase 1 preference. There was also a statistically significant difference among the three modes of presenting the materials. The findings revealed that learners transferred their attachment strategies from their mother tongue to English, which provided support for transfer hypothesis. The research findings on whether L2 learners can achieve native like patterns of ambiguity resolution is still less than conclusive and findings seem to suggest that L2 learners apply parsing strategies which are less automatized than native speakers and even at odds with some studies reporting no transfer of L1 parsing strategies. Language teachers should make their learners cognizant of relative clause attachment preferences in English to avert their transfer of their mother tongue strategies in determining the antecedents of the relative clauses. [ABSTRACT FROM AUTHOR]

The aim was to develop an innovative technology for obtaining high-quality organic marble beef. In the experimental farm “Polyvanivka” of the Institute of Grain Crops NAAS the cultivation of bulls of the gray Ukrainian breed up to 30 months of age has been organized using fodder which is traditional for steppe zone of Ukraine. The work has been performed according to the research program of the National Academy of Agrarian Sciences of Ukraine no. 37 “System of work in populations and conservation of biological diversity of genetic resources of farm animals” (“Preservation of breed gene pool”). The expediency of organic production of high-quality marble beef obtained in the steppe zone of Ukraine from gray Ukrainian cattle has been proven. This breed has such economically useful features as the duration of production use, longevity, high growth energy (stable average daily gain over 1 kg), and the conversion of diet into products (feed consumption is 70–80 MJ per 1 kg of growth) correlating with the age of the animal, slaughter rates (>60%, meat content is >4 kg per 1 kg of bones, hard skin is >30 kg which belongs to the category of bull production). We have found that it is necessary to determine the cattle fatness not by subcutaneous fat which has no dietary value, but by the beef marbling as a sign of its quality which takes into account the presence of intramuscular and intermuscular fat including unsaturated fatty acids, vitamins A and D, as well as the amount of protein and moisture and taste and culinary features of the carcass flesh, such as tenderness, juiciness and aroma. This meets the requirements of the consumer. The proposals based on the results of research on technological changes in animal husbandry promote the development of meat cattle breeding and are of great economic importance for strengthening the health of the population and food safety in Ukraine.

Background. Chronic obstructive pulmonary disease (COPD) is often associated with musculoskeletal dysfunction, including skeletal muscle dysfunction, sarcopenia, osteoporosis, and obesity. The purpose was to assess skeletal muscle status and determine the prevalence of sarcopenia and sarcopenic obesity in patients with COPD. Materials and methods. 66 patients with COPD and 35 healthy subjects had been examined. Sarcopenia was established using EWGSOP2 criteria, and sarcopenic obesity was defined in the presence of sarcopenia with a body mass index > 25 kg/m² . Results. In 59.1 % of the patients with COPD, a decrease in skeletal muscle strength was found, in particular, by 28.2 % in women and by 39.1 % in men at GOLD 4 in comparison with GOLD 1 and by 40.7 % and 54.3 %, respectively, compared to the control. A decrease in leg circumference (by 16.3 % in women and by 20.8 % in men) was determined at GOLD 4 compared to GOLD 1. A decrease in walking speed by 20 % in women and by 27.3 % in men was determined at GOLD 4 in comparison with GOLD 1 and a reliable correlation inverse connection between age and walking speed (r = –0.72 — in women and r = –0.61 — in men). A significant decrease in the lean mass of the limbs was established in COPD patients over 45 years old and with GOLD 2, lean and fat mass indices — with GOLD 3, appendicular lean mass — with GOLD 4 and over 60 years old. A direct correlation link was established between the severity of COPD and android type of obesity (r = 0.41; p < 0.05). Conclusions. Sarcopenia was diagnosed in 66.7 % of the patients with COPD and 5.7 % of the control group, and sarcopenic obesity was diagnosed in 27.3 % of the patients with COPD. An increase in the share of sarcopenia was observed with age (from 50 % among young people to 91.7 % among subjects over 60 years old) and sarcopenic obesity (from 25 % of subjects under 45 years old to 55.6 % over 60 years old) and with increasing severity of COPD (from 20 % with GOLD 1 to 100 % with GOLD 4 and from 42.9 % with GOLD 1 to 50 % with GOLD 4, respectively). [ABSTRACT FROM AUTHOR]

The purpose of the study was to establish age-related changes of male bone tissue. Materials and methods. The study was conducted by the Department of Clinical Physiology and Pathology of the Musculoskeletal System of the State Institution “D.F. Chebotarev Institute of Gerontology by the National Academy of Medical Sciences of Ukraine”. It involved 342 healthy men aged 20 to 89 years without osteoporosis and osteoporotic fractures or any pathology with a confirmed impact on bone tissue, as well as any somatic pathology in the sub- and decompensation. The following methods of examination were used: questionnaire, anthropometric measurements, clinical and instrumental examination. Bone mineral density (BMD) was measured by the dualenergy X-ray absorptiometry machine “Prodigy, GEНС Lunar” at the level of the entire skeleton, lumbar spine (L1- L4), proximal femur and femoral neck, distal and ultra-distal forearm bones. Results. We have detected a significant 14.8 % decrease of BMD at the level of femoral neck in the group of men aged 60–69 years, by 20 % in the group of men aged 70–79 years, and by 24.1 % in the group of men aged 80–89 years compared to the men aged 20–29 years; at the same time, at the lumbar spine there was registered a decrease of this parameter by 1.6 % in men aged 60–69 years, by 1.9 % in men of 70–79 years and by 0.8 % in men of 80–89 years, respectively. Among the examined practically healthy men, the bone tissue remained at the normal level relative to age in 67.8 %; osteopenia was detected in 27.8 %, and osteoporosis in 4.4 %. Conclusions. An age-associated BMD reduction was registered at various skeletal sites in the practically healthy men without any clinically significant factors affecting bone tissue metabolism. The most pronounced BMD loss was observed at the level of femoral neck. At the same time, 4.4 % of examined had osteoporosis without any clinical signs. [ABSTRACT FROM AUTHOR]

Мета. Визначити ступінь впливу незалежних один від одного передопераційних чинників на єдиний залежний чинник - тривалість госпіталізації пацієнтів із гострим коронарним синдромом після екстреної ендоваскулярної реваскуляризації міокарда. Матеріали і методи. Зібрано та статистично опрацьовано дані історій хвороб 40 пацієнтів віком до 60 років (1-ша група) та 40 пацієнтів віком 60 років і старше (2-га група). Методом статистичного опрацювання даних обрано кореляційно-регресійний аналіз. Результати. У пацієнтів 1-ї групи на тривалість госпіталізації впливали (в порядку зменшення значущості): передопераційні показники гемоглобіну та гематокриту, рівні тропоніну І та загального холестерину, ступінь оклюзії коронарних артерій, індекс маси тіла, фракція викиду лівого шлуночка та об’єм післяопераційної крововтрати. У пацієнтів 2-ї групи єдиним фактором, що істотно вплинув на тривалість госпіталізації, був вік. Висновки. Предикторами тривалості госпіталізації у віковій групі до 60 років слугують майже всі включені до дослідження незалежні фактори, тоді як у віковій групі 60 років і старше стійка кореляція характерна лише для фактора віку.

Стосовно матерії та законів фізики на підставі матеріалізації антиречовини в речовину розглянуто галактичний кругообіг органічної речовини, зокрема в Сонячній системі. Посилаючись на Біблію, він показує, що життя тваринного світу є на всіх планетах, але на різних їх рівнях і в різних формах, оскільки основою життя тваринного світу є вдосконалення біологічної клітини вищого світу, яка потрапила в Сонячну систему на планету Плутон і, рухаючись по її планетам, формується та вдосконалюється для самостійного життя поза її межами. Проведено дослідження прикладної науки Стародавнього світу, що зашифрована в Біблії, яка дає можливість розкрити фізичне явище послідовних близнюків, яке науці невідоме і суть якого не розкрито. Життя органічного світу Землі автор пов'язує з основою руху космічної водневої і сонячної вуглецевої матерії, як явищ природи. Зазначено, що воднева матерія, рухаючись з космосу по планетам Сонячної системи, які наділені різною енергетичною густиною, вимушена через життя тваринного світу змінювати свою полярність, рухаючись на Сонце, поставляючи йому водень, як паливо, для його життєдіяльності. Воднева матерія через життя тваринного світу змінює полярність матерії і лише тоді переходить на вищий енергетичний рівень. Вуглецева матерія, як продукт процесу синтезу на Сонці, виноситься квантами світла і розсіюється по планетам своєї системи, утворюючи рослинний світ. Наголошено, що тваринний світ стоїть на вході матерії в Сонячну систему, а рослинний світ – на її виході. Визначено три форми життя людини на Землі та її фізіономічні видозміни залежно від рівнів ядрового наповнення: Земного, Місячного і Сонячного. Доведено, що енергетично немовля в утробі матері живе на водневій космічній матерії, яка поступає на земну поверхню з ядра Землі. На цій матерії живе і розвивається плід упродовж 270 діб. Народившись, людина переходить жити впродовж природних 120 років на вуглецеву сонячну матерію, яка поступає на земну поверхню місячними циклами руху матерії. Вперше розкрито суть третьої форми життя людини на Землі, коли людина із 120-літного віку переходить жити впродовж 1000 років на вуглецеву матерію, але вже не місячними, а сонячними циклами. Розкриваються властивості людини, переведеної у третю форму життя, та її інтелектуальний рівень. Наголошено, що Біблія, як інструкція життя людини на Землі, є священною книгою християнського світу, яка має рішення будь-якої проблеми, а тому дає людям надію та впевненість у завтрашньому дню, захищає людство від прогресу, якого людина побоюється.

Наведено результати дослідження лісотипологічного потенціалу основних лісотвірних порід насіннєвого та вегетативного походження. Виявлено низку відмінностей між темпами росту та продуктивністю насіннєвих і порослевих насаджень основних лісотвірних порід Поділля. З'ясовано, що різниця між запасами дуба звичайного вегетативного походження модальних та оптимальних деревостанів чітко простежується вже у 2 класі віку. Найбільша різниця в запасі проявляється у віці 100 років і становить майже 50 %. Встановлено, що у дубових деревостанах насінного походження різниця між оптимальними та модальними деревостанами найбільше проявляється у 110-річному віці і продовжує зростати до 140 років. Також вивчено лісотипологічний потенціал насіннєвих ясеневих деревостанів. У ході проведених досліджень з'ясовано, що значне зниження запасу модальних ясеневих деревостанів спостерігається у 80–100-річному віці. Підраховано, що у 140-річному віці запас деревини в модальних деревостанах виявився на 170 м3∙га-1 нижчим, ніж в оптимальних. У букових деревостанах з віком відмінності за запасом між оптимальними і модальними показниками значно посилюються і у 80-річному віці різниця становить 100 м3∙га-1. За зведеними даними, середній оптимальний запас для основних деревостанів Поділля становить близько 340 м3∙га-1. Величина фактичного запасу становить 237 м3/га. Відхилення середніх запасів деревостанів становить 104 м3∙га-1 (32 %). Найбільші втрати від недовикористання лісорослинного потенціалу та запровадження неефективних лісогосподарських методів характерне для дубових (50,1 %) та букових (30,3 %) деревостанів. Згідно з отриманими даними встановлено, що основна частка втрат продуктивності деревостанів зумовлена недовикористанням лісорослинного потенціалу (32,04 %). Втрата від інших факторів є незначною і не перевищує 1 % від загального запасу деревини.

Copyright of Slobozhanskyi Herald of Science & Sport is the property of Kharkiv State Academy of Physical Culture and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of International Journal of Endocrinology / Mìžnarodnij Endokrinologìčnij Žurnal is the property of Zaslavsky O.Yu and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Chronic kidney disease puts an individual at a higher risk of all-cause and cardiovascular death. Coronary artery calcium score reflects the accumulation of calcium in the walls of the coronary arteries and a higher coronary artery calcium score is associated with lower survival rates. It is unclear if control of conventional risk factors is enough to reduce cardiovascular risk in patients with chronic kidney disease. The aim of this study was to investigate if the association between estimated glomerular filtration rate and coronary artery calcium score in the Ukrainian population differs by sex, age, blood pressure, and total cholesterol. This cross-sectional study was conducted on a sample of patients who underwent measurement of coronary artery calcium score at Dnipropetrovsk Mechnikov Regional Hospital, Dnipro, Ukraine. Inclusion criteria: age >40 years old, available data about coronary artery calcium score and estimated glomerular filtration rate. Exclusion criteria: the presence of known cardiovascular disease, diagnosis of diabetes mellitus, estimated glomerular filtration rate <30 ml/min and extreme coronary artery calcification (coronary artery calcium score >1500 Agatston units). 137 patients (54 males and 83 females), median age 59.0 [54.0;67.0] years were enrolled in the study. In the patients with lower eGFR there was non-significantly higher coronary artery calcium score (p=0.07). In males with eGFR ≥90 ml/min, 60-89 ml/min, and 30-59 ml/min coronary artery calcium score didn’t differ significantly, while in females a lower estimated glomerular filtration rate was associated with a higher coronary artery calcium score. A lower estimated glomerular filtration rate was significantly associated with a higher coronary artery calcium score in the patients with systolic blood pressure ≥140 mmHg (p=0.04), but not in patients with diastolic blood pressure ≥90 mmHg. In the patients with total cholesterol <5.0 mmol/l and ≥5.0 mmol/l coronary artery calcium score tended to be higher in the patients with lower estimated glomerular filtration rate. A lower estimated glomerular filtration rate in our study was associated with a higher coronary artery calcium score in females, patients aged ≥55 years old and in patients with systolic blood pressure ≥140 mmHg. [ABSTRACT FROM AUTHOR]

Background. The purpose of the study is to determine the reference intervals of carboxy-terminal telopeptide of type I collagen (β-CTX) in the blood serum of healthy males and females of various ages, residents of Ukraine. Materials and methods. The study included 4754 individuals aged 20-89 years (4123 women (mean age 59.6 ± 13.6) and 631 men (mean age 49.5 ± 16.3)). All participants were divided into 7 groups by the age decades (from 20 to 89 years), and three groups of 40-49, 50-59 and 60-69 year-olds were additionally divided into the subgroups by five years. Furthermore, the patients were divided according to the gerontological classification of age into 4 groups: young - 20-44 years, middle-age - 45-59 years, elderly - 60-74 years, and old - 75-89 years. The blood serum β-CTX concentration was determined by ECLIA electrochemiluminescence immunoassay on the cobas e 411 analyzer. Results. We have detected significant effect of age on serum β-CTX variability: a significant increase in β-CTX levels in women (F = 15.48, p < 0.00001), and a decrease in men (F = 11.73, p < 0.00001) with age. The significantly lower levels of β-CTX were found in the women aged 20-29 (F = 35.68, p < 0.00001) and 30-39 years (F = 19.47, p = 0.00001) compared to the men of similar ages. However, the women of 65-69 years (F = 10.50, p = 0.001) had a significantly higher serum β-CTX levels compared to men of the same age group. Conclusions. The serum β-CTX levels have been associated with age: in men they are decreasing significantly with age, in women - significantly increasing. In the young men aged 20-44 years and women aged 65-69 years, the β-CTX concentration was significantly higher compared with that of the opposite sex subjects of a similar age. The findings on β-CTX serum levels in the practically healthy men and women of various ages, who are residing in this country, may be used as the reference intervals for the Ukrainian population. [ABSTRACT FROM AUTHOR]

Background. The purpose of the study is to determine the serum level of N-terminal propeptide of type I procollagen (PINP) in healthy men and women of various ages. Materials and methods. The study included 1,568 individuals (1,422 females and 146 males, aged 20-89 years (mean age 60.36 ± 13.68 yrs). All patients were divided into 7 groups, by decades and according to the gerontological age classification: young age – 20–44 yrs, middle age 45–59 yrs, elderly 60–74 yrs, and old 75-89 yrs. During the study, we examined the effect of such demographic characteristics, as age and gender, on serum PINP level, using the electrochemiluminescence immunoassay ECLIA on the cobas e 411 analyzer. Results. We have detected no significant effect of age on the serum variability of PINP in females (F = 1.453, p = 0.19). However, we observed a significant decrease of PINP level in the female age groups of 40–49 yrs (47.74 ± 21.31, p = 0.02), 60–69 yrs (49.76 ± 25.75, p = 0.03), 70–79 yrs (50.49 ± 26.71, p = 0.04), compared with the age group of 20–29 yrs (58.67 ± 27.46). The regression analysis revealed a significant decrease of PINP level with age in young women and men (20–44 years). When comparing serum PINP level in the oldest age group (80-89 years), we detected its increase in women (55.20 ± 28.38 ng/ml), compared with the 70–79 years group (50.49 ± 26.71 ng/ml), and its decrease in men (54.87 ± 28.24 and 39.16 ± 12.46 ng/ml, respectively). In men, we revealed significant effect of age on the serum variability of PINP (F = 3,077, p = 0.007). Conclusions. The regression analysis showed a significant decrease in PINP level with age in men and women of 20-44 years. In men, we detected a significant effect of age on the variability of serum PINP level. A comparison of serum PINP levels in the oldest age group of 80-89 revealed its increase in women, compared to the 70–79 age group, and decrease in men. The obtained results may be used as reference values for PINP level in serum among representatives of the Ukrainian population of various ages and sexes. [ABSTRACT FROM AUTHOR]

In acute experiments on different age group of 30 white wild-type rats: juvenile (weight 130–175 g), mature (weight 200–250 g) and old (weight 300 g and more) we were investigated the changes in the volume rate of bile secretion with cyclooxygenase inhibition by acetylsalicylic acid (100 mkg/kg weight of animal) which is a blocker of the prostaglandin synthesis enzyme. We were explored the changes of the level of choleresis and bile biochemical components by thin-layer chromatography In vivo. The relative abundances of cholecycle, henodeoxycholic, taurocholic and glycocholic bile acids in the liver of rats were determined by chromatography, with the subsequent densitometry. The biliary acid flow rate was calculated as the sum of the bile acid concentration multiplied by the volume of secreted biliary in one relevant thirty-minute sample. The conjugation coefficients were calculated for each thirty minute sample. Reduction of bile secretion by endogenous prostanoids was shown, because inhibition of prostaglandins synthesis caused the hypercholeresis on 42–112,5 % in different rat age groups, compared to control. Endogenous prostaglandins suppressed the processes of conjugation in old and juvenile age group on 117–189,1 %, in contrast these regulators have no significant effect on bile acids association with glycine and taurine in mature rats. The binding of endogenous prostanoids probably increased the conjugation processes in juvenile rats, whereas in the old experimental group acetylsalicylic acid was significantly reduced by 123 % on average. Analysis of changes in free and conjugated bile acids in the rats of different age groups showed that the ratio of qualitative changes in structure of the liver bile in rats with the cyclooxygenase blockade is mainly due to enhanced synthesis of free bile acids de novo. Therefore, endogenous prostanoids affect in the opposite way. There are have multi-directional impact on bile secretion in different age groups of rat that means ambiguous role of these drugs in liver function regulation at different stages of ontogenesis. [ABSTRACT FROM AUTHOR]

Copyright of Pocki is the property of Zaslavsky O.Yu and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of International Journal of Endocrinology / Mìžnarodnij Endokrinologìčnij Žurnal is the property of Zaslavsky O.Yu and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The efficiency of the hatchery is determined by the quality indicators of the hatching eggs and the technology of incubation. Therefore, studies aimed at determining the optimal quality indicators of hatching eggs and technological solutions for their incubation are relevant. Eggs of hens of the meat cross Kobb-500 at the ages of 26-, 37-, 48-, 51- and 63 weeks were incubated a􀅌er their pre-incubation storage for 4, 5, 7 and 8 days. Depending on the age of the hens were found the significant variation of the level of fertilization of eggs. The highest level (95,5 ... 96,5 %) of fertilization of eggs was established at the incubation of eggs of hens at 37 weeks of age. A significant decrease was observed in the 63-week-old hens. It was found that with an increase of storage term of hatching eggs, the level of hatchability of eggs and chicken hatching decreases. Depending on the age of the hens, a variation in these indicators was noted. The highest level of hatchability of eggs of 26-week-old hens was established during their storage at 5 and 8 days (90.6 and 90.3%). The level of hatchability of eggs of 37-51 week-old hens varies within 86,4 ... 95,47%. The highest values of this indicator were set at incubation of eggs of 37-48 week-old hens. For poultry at the end of productive use (63 weeks), the hatchability egg rate is lower - 86.4 ... 90.9 %. As for the variation of the index of hatchability depending on the storage terms, for each age group the difference was 2.32 ... 3.96%. There was no decrease in the rate of hatchability with an increase in storage terms from 4 to 8 days. This demonstrates the feasibility of storing eggs throughout this period. When incubating eggs obtained from a young hens, the number of "dead-in-shell" and "late dead" is higher in comparison with other experimental groups. When incubating eggs obtained from hens at the age of 51-63 weeks, the number of weak chickens increases (up to 1.99%). This is especially evident when extending egg storage to 7-8 days. Therefore, when assessing the incubation quality of eggs of the specialized meat cross "Cobb-500" with a storage term of 4-8 days the age of the parent stock is decisive. [ABSTRACT FROM AUTHOR]

Exact causes of contradictions in the understanding of relapsing course as characteristic phenomenon of multiple sclerosis (MS) and primarily relapsing-remitting type are still considered to be “sub rosa”. We tried to determine connection and correlation between seasonal dynamic factors, chronometric parameters of disease progression (age, disease duration) and frequency of relapses and the role of gender differences as well. A four-year prospective study included complete registration of all cases of MS exacerbations in resident patients with a relapsingremmiting course of the disease according to McDonald criteria in Volyn region of Ukraine in 2010. Each patient had neurological score based on EDSS scale to ensure compliance with inclusion criteria. 128 patients (44 males and 84 females) with a remitting-recurring course of the disease were involved in this study. Statistical analysis was performed using SPSS 18, MedCalc and Microsoft Excel software using standard descriptive statistics, correlation and regression analysis. In total, 197 cases of MS relapses were registered. Episodes of relapses prevailed in winter-spring period. Multiple regression model including suggested climate factors showed multiple correlation coefficient – 0.55 (p<0.01). The prevalence of MS was higher in females, while general incidence of recurrences was similar to males. However, relapse rate in different age groups differs: the rate of recurrence increases in women aged after 50 years (mean annualized relapse rate (ARR)=0.66), while it slowly decreases in men with aging. The duration of the disease did not have significant effect on the course of MS in women, whereas weak negative relationship (0.24, p<0.001) between the duration of the disease and the frequency of MS in men was showed. Correspondingly, the average negative correlation (-0.37, p<0.001) was detected between the age of disease onset and the incidence of MS recurrence in males, while this connection was not observed in females. We established that the recurrence of MS is a result of multifactorial influence of external and internal factors. Individual seasonal climate variability did not have sufficient force of influence. Therefore, combined effect of corresponding climate changes played a significant role. Furthermore, it is quite probable that interactions of MS with external factors influencing the human body can be mutually integrated. [ABSTRACT FROM AUTHOR]

Наведено лісівничо-таксаційну характеристику дослідного матеріалу з оцінювання біотичної продуктивності деревостанів головних лісотвірних видів Національного природного парку "Вижницький". Зібрані експериментальні дані відображають основні таксаційні показники для найтиповіших лісорослинних умов деревостанів ялиці білої, бука лісового та ялини європейської. Дослідні дані в подальшому буде використано для розроблення адекватних математичних моделей компонентів фітомаси та побудови системи нормативно-інформаційного забезпечення основних таксаційних та біотичних параметрів дерев і деревостанів.

Подано результати дослідження динаміки фітомаси лісових екосистем парку-пам'ятки садово-паркового мистецтва загальнодержавного значення "Феофанія". На основі методів аналізу визначено обсяг фітомаси стовбурів у корі, гілок, листя, коренів, підліску і підросту та живого надґрунтового покриву в різні роки понад 50-річного періоду. Встановлено динаміку структури загальної фітомаси лісових екосистем парку "Феофанія". Сучасною структурою фітомаси лісів є 62 % фітомаси стовбурів у корі, 23 % коріння, 10 % гілок у корі, 1 % листя, 2 % підліску і підросту та 2 % живого надґрунтового покриву. Визначено, що щільність фітомаси в абсолютно сухому стані на одиницю площі протягом досліджуваного періоду збільшилася на 80,7 % – до 10,35 кг·м-2.

This article analyzes peculiarities of the melodic composition of pre-terminal part of a sense-group in the speech of native speakers of American English who are representatives of different age and gender groups living on the territory of the United States. The present investigation is dedicated to the analysis of the melodic characteristics of American representatives of different age and gender groups’ speech. Age is considered the basic of human being, it defines the boundaries of human development and social opportunities of a person. Often age demands from the individual the corresponding behavior. Judging by the opinion of sociophoneticians age changes in speech touch the whole spectrum of prosodic components including dynamic ones, however age can’t be considered the only factor, influencing the peculiarity of individual’s speech behavior. Majority of investigations prove that there is also an interconnection between gender and territorial peculiarities of the speech. A person presents a complex unity of personal and social principles, which means that any changes, which occur are defined by the variety of physiological and social forces. The conducted instrumental investigation showed that dynamic characteristics of speech are quite informative for defining age identification of American variant representatives.

Опрацьовано таксаційні описи лісових господарств досліджуваного регіону і підібрано найбільш репрезентативні ділянки для закладання тимчасових пробних площ. За результатами польових і лабораторних досліджень, що оброблялися на ПК за допомогою спеціально розроблених прикладних програм, зібрано потрібний матеріал для оцінювання біотичної продуктивності штучних соснових деревостанів Південного Придніпровського Полісся. Наведено лісівничо-таксаційну характеристику дослідних даних, яка дасть змогу розробити адекватні математичні моделі фітомаси і мортмаси деревостанів за їх окремими компонентами (деревина стовбура у корі, кора стовбура, гілки крони та хвоя, сухостій, деревна ламань, пні) у штучних сосняках, побудувати систему нормативно-інформаційного забезпечення дослідження основних таксаційних і біотичних параметрів деревостанів, оцінити їх вплив на екологічний стан довкілля.

Досліджено особливості змін динаміки таксаційних показників сухостійних дерев у насадженнях берези повислої в Українському Поліссі. Встановлено за допомогою непараметричного кореляційного аналізу наявність великої кількості статистично значущих зв'язків між таксаційними параметрами живих і сухостійних дерев березового деревостану. Теоретично визначено середньозважений термін знаходження сухостійних дерев берези у складі деревостану залежно від його віку. Здійснено спробу розробити математичні залежності таксаційних показників сухостійних дерев від аналогічних показників живих дерев.

A detailed and comprehensive study of the ratio of thalamus size to somatotype and age is extremely relevant, as even minor variations may be crucial in diagnosing the development of cerebrovascular pathology. The aim of the study – to compare and analyze the age and somatotypological changes in CT-sizes of thalamus in apparently healthy young men and women of the Podilia region in Ukraine. Materials and Metohods. 82 apparently healthy boys and 86 girls were selected among directed by doctors to CT examinations youths aged from 17 to 21 and girls aged from 16 to 20 years in the third generation residents of Podilia region of Ukraine with suspected brain disease in which the diagnosis was not confirmed, after the additional test screening assessment of health (using a special questionnaire). Committee on Bioethics Vinnytsia National Medical University (protocol No. 10 dated 21.11.2013) found that studies fully satisfy the basic bioethical standards of the Helsinki Declaration, the European Convention on Human Rights and Biomedicine (1977) and the relevant provisions of the WHO and Ministry of Health Ukraine number 281 of 01.11.2000. CT brain research performed using spiral computed tomography “Select SP ” company EL scint (Israel) in the horizontal position of the patient on the back, head forward on a special stand for the head. Morphometry included definition of longitudinal and transverse sizes of the right and left thalamus at the level of T5. In all boys and girls anthropometric survey was conducted according to V. V. Bunak scheme in modification of P. P. Shaparenko. To evaluate the somatotype used scheme of J. L. Carter, B. H. Heath. Statistical analysis of the results conducted in the package STAT IST ICA 6.1 using nonparametric methods. Results and Discussion. In this work presented results boundaries of percentile scope and comparison of CT-sizes of thalamus in apparently healthy young men and women in Podilia region of Ukraine in age and somatotypological aspect. In young men, when dividing into different age groups, smaller values of the transverse size of thalamus are set in 19 years of age than those in 17 and 18 years of age; and when distributed into different somatotypes – larger sizes are in the representatives of the median intermediate and ectomorphic somatotype than in the mesomorphs and ectomesomorphs. In girls, when dividing into different age groups, smaller values are found for most sizes of thalamus in 18 and 20 year-olds than in other age groups; and when dividing into different somatotypes – larger sizes are in the mesomorphic somatotype than endomorphs, endo-mesomorphs and girls of the middle intermediate somatotype. Analysis of the data obtained, taking into account the distribution of somatotypes in different age groups of practically healthy young men and girls, indicates a greater impact of the features of the body structure on the size of the thalamus than age and gender. Conclusions. The comparison of sizes of the thalamus between the different age and somatotypological groups of apparently healthy young men or women from Podilia region of Ukraine supports the hypothesis of academician Nykytyuk about greater impact of type of body structure on the state of various morphological and functional parameters of the body (including the size of the thalamus) than age of and gender.

Copyright of Slobozhanskyi Herald of Science & Sport is the property of Kharkiv State Academy of Physical Culture and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Background. Deficiency and insufficiency of vitamin D is a pandemic of the 21st century. Obese patients have a lower vitamin D level, but the literature data are contradictory. The purpose of this study is to examine 25(OH)D level depending on body mass index (BMI) in postmenopausal women. Materials and methods. One thousand seven women aged 50–89 years were examined: their mean age was 65.74 ± 8.61 years; mean height — 1.61 ± 0.07 m; mean weight — 70.65 ± 13.50 kg; mean BMI — 27.27 ± 4.86 kg/m2 and mean 25(OH)D levels in the blood serum — 26.00 ± 12.00 nmol/l. The patients were divided into the following 6 groups depending on their BMI: group I — 338 women with a normal body weight, group II — 16 persons with an insufficient body weight, group III — 382 individuals with an excessive body weight, group IV — 199 women with class I obesity, group V — 60 persons with class II obesity, and group VI — 12 individuals with class III obesity. Results. Vitamin D deficiency was found in 34.4% of postmenopausal women, insufficiency — in 31.4%. 25(OH)D levels were significantly lower in women with class I obesity (23.60 ± 10.24 ng/ml) and class II obesity (22.38 ± 10.34 ng/ml), compared with women who had a normal body mass (28.24 ± 12.99 ng/ml), p = 0.00003. The study results reveal a weak correlation between 25(ОН)D level and BMI (r = 0.15). Conclusions. In women with obesity, BMI significantly influences vitamin D level, and this influence does not depend on the season. [ABSTRACT FROM AUTHOR]

Small and medium-sized enterprises are facing many types of business risks, almost unknown or unimportant for the large companies, where the funding risk plays an essential role due to the importance of the need of the external financial sources for their growth. This paper investigates the impact of a size of the company and an age of the owner on the perception of the funding risk in the segment of small and medium-sized enterprises in Slovakia in response to the restraints in their access to credit finance. The results of the research specify the importance of these factors in determining the scope of the funding risk exposure on Slovak SMEs. The paper is based on the data from the scientific research carried out in 2016 in Slovakia among 438 companies. The data were analyzed by Pearson's chi-square statistics, which allowed to confirm the existence of the statistically significant dependencies between the chosen factors and the perception of the funding risk. The presented statistical evidence confirms that the size of the company and the age of the owner are significant in relation to the funding risk of a company from the segment of SMEs. Smaller companies do perceive the funding risk more intensively than larger ones. The statistically significant impact of the selected factors on the frequency of bank loans rejection was confirmed only in case of the age of the owner, but not in case of the size of the company, when the entrepreneurs of the age between 36 and 45 declared the highest rejection rate of the loan applications. A surprising finding is that younger entrepreneurs are significantly more self-confident in case of the potentially negative influence of the funding risk on their companies than their older colleagues. The results of the research also confirm the existence of the statistically significant dependence between the selected factors and the reasons for the rejection of bank loans applications. We can declare that a credit rejection is most common in case of younger business owners but is not typical for the smaller companies. In the group of entrepreneurs aged between 36 and 45 years the most frequent reason was related to the negative values of the financial indicators, and in case of the oldest entrepreneurs the most often reasons of the rejection of the loan application were the lack of collateral, poor business plan and negative values of the financial indicators. [ABSTRACT FROM AUTHOR]

The occupational morbidity in Kharkov region has been researched over the period of 2012-2016. The dynamics of the number of patients with occupational diseases in this region is practically the same as in Ukraine. Most of such patients are males. However, the number of females increased over this period. According to the record of work in hazardous working environments, the biggest number of patients is observed among those employees who have worked for 20-29 years, then those who have worked for over 30 years, followed by those who have 10-19 years of work record and finally, with less than 10 years of work record. According to the age, the biggest number of patients is among workers at the age of 50-59. They are followed by those who are in their sixties. The third biggest number is among aged 40-49, the fourth – aged 30-39, and the fifth – aged 20-29. In the atructure of occupational pathology (38,67-49,71) of all the occupational diseases accounts for chronic bronchitis, COPD, and pneumoconiosis. The next common disease (29,59-37,33%) is occupational neurosensory hearing loss. It was revealed that 3,37-6,25% of the total number of workers suffer from 4 occupational diseases, 2-3 and 1 occupational diseases were detected in 52,50-72,97% and 21,21-43,82% employees accordingly. The presence of 2-4 occupational diseases points at the combined exposure to hazards of working environment and working process in engineering workers, and inefficient activity of health care institutions that are responsible for periodic medical examinations. The fact that the diseased are mostly people in their fifties and sixties, and those who have a long record of work, indicates to the necessity to implement the time protection technique with a view to reducing the level of occupational morbidity. The highest rate of morbidity was observed in Kharkov engineering industry. That is why it is vitally important to provide the enterprises of this industry with State public health monitoring system. [ABSTRACT FROM AUTHOR]

In pathogenesis damage of the testis an important role belongs to blood-vessels bed especially its arteries. It is necessary to indicate that quantitative morphological changes of age peculiarities of remodelling of testis arteries is not fully studied. The aim of the study – quantitative morphological investigation of age peculiarities of remodeling of testis arteries in experimental animals. Materials and Methods. By complex morphological methods we studied middle (external diameter 51–125 mkm) and small (external diameters 26–50 mkm) arteries of testis in 17 white rats which were divided into 2 groups: the first group – nine 8-months rats (young animals); the second group – eight 24-months rats (old animals). Euthanasia of animals was performed by bloodletting in terms of thiopental anesthesia. By morphometrical methods on histological preparations we determined external and internal diameters arteries of testis, thickness of media, index Vogenvorta (relations area of vessel to area its aperture), height of endotheliocytes, diameter its nucleus, nucleo-cytoplasmatical relations in this cells, comparatively volume damaging endotheliocytes. Processing of quantitative data produced by the method of variation statistics. Results and Discussion. Analysis of the results revealed that with age quantitative morphological characteristics of small calibre arteries of testis is more pronounced. It was found out that with age, the outer diameter of small arteries increased by 3.3 %, the thickness of the media – by 11.3 %, the Vohenvort index – 41.1 %, the internal diameter of blood vessels decreased by 11.0 %. The relative amount of damaged endothelial cells in arteries of small calibre testes in animals older increased by 21.9 %, which most researchers associated with the growth of age apoptosis. Nuclear-cytoplasmic ratio in the endothelial cells of arteries of medium and small sizes did not change with age, indicating the structural stability of cellular homeostasis. Age wall thickening studied vascular narrowing of the lumen, the growth index Vohenvorta indicate a reduction of capacity and deterioration of blood supply to the studied organ. Conclusions. The age peculiarities of remodelling of testis arteries in laboratory white rats have been studied by means of quantitative morphological methods. It has been established that in testis increase arterial wall, space contraction, blood supply wоrsening of organ. Small-sized arteries got more expressed structural rearrangement.

Occupational morbidity in Kharkov region has been researched over the period 2006-2015. The dynamics of the number of patients with occupational diseases in this region is practically the same as in Ukraine but there are some differences. Most of such patients are males. However, the number of females increased over this period. The employees exposed to occupational hazards with the 20-29-year record of work comprise the biggest share of all the victims. They were followed by the employees with the record of work amounting more than 30 years, 10-19 years and, finally, less than 10 years. According to the age, the biggest number of patients is among workers at the age of 50-59. They are followed by those who are in their sixties. The third biggest number is among 40-49 aged, the fourth - 30-39 aged, and the fifth - 20-29 aged. The biggest share (39.89-50.60%) in the structure of occupational diseases is chronic bronchitis, COPD and pneumoconiosis. The next common disease (25.9033.80%) is occupational hearing loss. It was revealed that 5-8% of the total number of workers suffer from four occupational diseases, 52-62% - from two-three, one occupational diseases was detected in 32-40% of employees accordingly. The presence of 2-4 occupational diseases points to the combined exposure to occupational hazards of machine engineering workers. During this period, the biggest number of the victims (79.17-90.43%) was registered in machine engineering due to regional peculiarities of economics. The fact that the victims are mostly people aged 50-59 years and over 60, having a long record of service indicates the necessity to implement the technique of protection of workers by time. The highest rate of morbidity was observed in Kharkov Tractor Plant and Kharkov Malyshev Plant. Thus, it is vitally important to conduct preventive activities in these enterprises first and foremost. [ABSTRACT FROM AUTHOR]

Background. Vitamin D deficiency is prevalent in all the world countries. Recent studies show the correlation between vitamin D deficiency and musculoskeletal disorders. The purpose of this study is to examine vitamin D deficiency and insufficiency prevalence in patients of various ages, who have musculoskeletal disorders, and to reveal the influence of seasonal factors on these conditions. Materials and methods. 3460 patients of the Ukrainian scientific Medical Center of Osteoporosis Problems, aged 1 to 92 years, who were referred by other specialists to the center for bone state evaluation, were examined. A majority of the patients presented with osteoporosis and its complications, spinal osteochondrosis, knee and hip osteoarthritis (mean age — 52.90 ± 21.10 years). Most of the patients were women (83.5 %). 25(OH)D and parathyroid hormone analyses were performed by means of electrochemiluminescent method (Elecsys 2010 analyzer, Roche Diagnostics, Germany) and cobas test-systems. Statistics 6.0 software package (Copyright StatSoft, Inc., 1984-2001) was also used. Results. Among the patients with musculoskeletal pathology, the highest 25(OH)D level was noted in the age group of 1-9 years and the lowest — in the age group of 80 and over. Age negatively influenced 25(OH)D values. Prevalence of vitamin D deficiency among the patients with musculoskeletal pathology was 37.3 %, vitamin D insufficiency — 30.6 %; 32.1 % of patients had normal vitamin D status. Normal 25(OH)D level was found in 38.0 % of children, 33.2 % of adults and in 29.6 % of elderly patients. Month of blood sampling had a significant influence on 25(OH)D content (F = 7.49; p < 0.001). The highest significant differences in 25(OH)D levels during the summer vs. winter months were observed in the age groups of 10-19 (18.2 %), 40-49 (17.3 %), 30-39 (16.2 %) и 1-9 years (16.1 %). There were no significant seasonal differences observed in the elderly patients (60 years and older) with musculoskeletal pathology. Conclusions. Despite the combined calcium and vitamin D supplementation in most patients with musculoskeletal pathology, only 37.9 % of children, 33.2 % of adults and 29.6 % of the elderly people had normal 25(OH)D values and thus required screening examination of vitamin D level in patients with musculoskeletal disorders and additional vitamin D prescription (Guidelines for the Central and Eastern Europe). [ABSTRACT FROM AUTHOR]

Copyright of International Journal of Endocrinology / Mìžnarodnij Endokrinologìčnij Žurnal is the property of Zaslavsky O.Yu and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Розглянуто методику оптимізації фізичного стану жінок першого періоду зрілого віку засобами інноваційних фітнес-технологій (на прикладі аквааеробіки та фітнесу). В експерименті взяли участь 20 жінок 21–35 років,яких розділили на дві групи для занять фітнесом та аквааеробікою. Для кожної з груп розроблено та запропоновано спеціальні оздоровчі комплекси відповідно до їхнього фізичного стану. Установлено, що розроблений оздоровчо-тренувальний комплекс із використанням засобів аквааеробіки дав змогу досягти більш вагомих результатів у підвищенні фізичного стану та аеробної продуктивності жінок зрілого віку. Рекомендовано напрями розробки інноваційних технології контролю фізичного стану, засобів і методів оздоровчого тренування жінок цієї категорії.