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8 results on '"A. Degulys"'

1. EFFICACY AND SAFETY OF LUSPATERCEPT VERSUS EPOETIN ALFA IN ERYTHROPOIESIS-STIMULATING AGENT (ESA)-NAIVE PATIENTS WITH TRANSFUSION-DEPENDENT LOWER-RISK MYELODYSPLASTIC SYNDROMES (LR-MDS): FULL ANALYSIS OF THE COMMANDS TRIAL

Author

G. Garcia-Manero, U. Platzbecker, V. Santini, A. Zeidan, P. Fenaux, R. Komrokji, J. Shortt, D. Valcarcel, A. Jonasova, S. Dimicoli-Salazar, I.S. Tiong, C.-C. Lin, J. Li, J. Zhang, A.C. Giuseppi, S. Kreitz, V. Pozharskaya, K. Keeperman, S. Rose, T. Prebet, A. Degulys, S. Paolini, T. Cluzeau, and M. Della Porta

Subjects
Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Introduction: We report the full analysis of the COMMANDS trial assessing efficacy and safety of luspatercept versus epoetin alfa (EA) in ESA-naive patients with LR-MDS. Methods: 363 patients (aged ≥18 y, with transfusion-dependent LR-MDS, serum erythropoietin

Published
2024
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2. EFFICACY AND SAFETY OF LUSPATERCEPT VERSUS EPOETIN ALFA IN ERYTHROPOIESIS-STIMULATING AGENT (ESA)-NAIVE PATIENTS WITH TRANSFUSION-DEPENDENT LOWER-RISK MYELODYSPLASTIC SYNDROMES (LR-MDS): FULL ANALYSIS OF THE COMMANDS TRIAL

Author

Garcia-Manero, G, Platzbecker, U, Santini, V, Zeidan, A, Fenaux, P, Komrokji, R, Shortt, J, Valcarcel, D, Jonasova, A, Dimicoli-Salazar, S, Tiong, IS, Lin, C-C, Li, J, Zhang, J, Giuseppi, AC, Kreitz, S, Pozharskaya, V, Keeperman, K, Rose, S, Prebet, T, Degulys, A, Paolini, S, Cluzeau, T, Porta, MD, Garcia-Manero, G, Platzbecker, U, Santini, V, Zeidan, A, Fenaux, P, Komrokji, R, Shortt, J, Valcarcel, D, Jonasova, A, Dimicoli-Salazar, S, Tiong, IS, Lin, C-C, Li, J, Zhang, J, Giuseppi, AC, Kreitz, S, Pozharskaya, V, Keeperman, K, Rose, S, Prebet, T, Degulys, A, Paolini, S, Cluzeau, T, and Porta, MD

Published
2024

3. S102: LUSPATERCEPT VERSUS EPOETIN ALFA FOR TREATMENT (TX) OF ANEMIA IN ESA-NAIVE LOWER-RISK MYELODYSPLASTIC SYNDROMES (LR-MDS) PATIENTS (PTS) REQUIRING RBC TRANSFUSIONS: DATA FROM THE PHASE 3 COMMANDS STUDY

Author

Della Porta, Matteo Giovanni, primary, Platzbecker, Uwe, additional, Santini, Valeria, additional, Zeidan, Amer M., additional, Fenaux, Pierre, additional, Komrokji, Rami S., additional, Shortt, Jake, additional, Valcárcel, David, additional, Jonášová, Anna, additional, Dimicoli-Salazar, Sophie, additional, Tiong, Ing Soo, additional, Lin, Chien-Chin, additional, LI, Jiahui, additional, Zhang, Jennie, additional, Carolina Giuseppi, Ana, additional, Kreitz, Sandra, additional, Pozharskaya, Veronika, additional, Keeperman, Karen L., additional, Rose, Shelonitda, additional, Shetty, Jeevan K., additional, Hayati, Sheida, additional, Vodala, Sadanand, additional, Degulys, Andrius, additional, Paolini, Stefania, additional, Cluzeau, Thomas, additional, and Garcia-Manero, Guillermo, additional

Published
2023
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4. EFFICACY AND SAFETY OF LUSPATERCEPT VERSUS EPOETIN ALFA IN ERYTHROPOIESIS-STIMULATING AGENT (ESA)-NAIVE PATIENTS WITH TRANSFUSION-DEPENDENT LOWER-RISK MYELODYSPLASTIC SYNDROMES (LR-MDS): FULL ANALYSIS OF THE COMMANDS TRIAL

Author

Garcia-Manero, G., Platzbecker, U., Santini, V., Zeidan, A., Fenaux, P., Komrokji, R., Shortt, J., Valcarcel, D., Jonasova, A., Dimicoli-Salazar, S., Tiong, I.S., Lin, C.-C., Li, J., Zhang, J., Giuseppi, A.C., Kreitz, S., Pozharskaya, V., Keeperman, K., Rose, S., Prebet, T., Degulys, A., Paolini, S., Cluzeau, T., and Porta, M. Della

Published
2024
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6. Efficacy and Safety of Luspatercept Versus Epoetin Alfa in Erythropoiesis-Stimulating Agent (ESA)-Naive Patients (Pts) with Transfusion-Dependent (TD) Lower-Risk Myelodysplastic Syndromes (LR-MDS): Full Analysis of the COMMANDS Trial

Author

Garcia-Manero, Guillermo, Platzbecker, Uwe, Santini, Valeria, Zeidan, Amer M., Fenaux, Pierre, Komrokji, Rami S., Shortt, Jake, Valcarcel, David, Jonasova, Anna, Dimicoli-Salazar, Sophie, Tiong, Ing Soo, Lin, Chien-Chin, Li, Jiahui, Zhang, Jennie, Giuseppi, Ana Carolina, Kreitz, Sandra, Pozharskaya, Veronika, Keeperman, Karen L., Rose, Shelonitda, Prebet, Thomas, Degulys, Andrius, Paolini, Stefania, Cluzeau, Thomas, and Della Porta, Matteo Giovanni

Published
2023
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7. Acremonium sclerotigenum-Acremonium egyptiacum: a multi-resistant fungal pathogen complicating the course of aplastic anaemia

Author

A. Degulys, A. Aline-Fardin, Jean-Pierre Marie, B. Rio, Eric Dannaoui, Juliette Guitard, G. Buot, Simona Lapusan, and Christophe Hennequin

Subjects
Microbiology (medical), Adult, Male, medicine.medical_specialty, Antifungal Agents, severe aplastic anaemia, Acremonium egyptiacum, Microbiology, chemistry.chemical_compound, Echinocandins, Lipopeptides, Caspofungin, Drug Resistance, Fungal, Internal medicine, Amphotericin B, Acremonium sclerotigenum, Medicine, Humans, caspofungin resistance, Voriconazole, Hematology, biology, business.industry, Acremonium, Anemia, Aplastic, General Medicine, Fungal pathogen, Triazoles, amphotericin B resistance, opportunistic infections, biology.organism_classification, Resistant tuberculosis, Virology, Infectious Diseases, Pyrimidines, chemistry, Mycoses, business, medicine.drug
Abstract

A patient with aplastic anaemia, successively treated with caspofungin then liposomal amphotericin, developed a disseminated infection due to Acremonium, further confirmed as resistant in vitro to these drugs. Successful treatment was achieved with voriconazole. Multiple antifungal treatments may expose to the risk of breakthrough of multi-resistant pathogens in haematology patients.

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8. S102: LUSPATERCEPT VERSUS EPOETIN ALFA FOR TREATMENT (TX) OF ANEMIA IN ESA-NAIVE LOWER-RISK MYELODYSPLASTIC SYNDROMES (LR-MDS) PATIENTS (PTS) REQUIRING RBC TRANSFUSIONS: DATA FROM THE PHASE 3 COMMANDS STUDY

Author

Matteo Giovanni Della Porta, Uwe Platzbecker, Valeria Santini, Amer M. Zeidan, Pierre Fenaux, Rami S. Komrokji, Jake Shortt, David Valcárcel, Anna Jonášová, Sophie Dimicoli-Salazar, Ing Soo Tiong, Chien-Chin Lin, Jiahui LI, Jennie Zhang, Ana Carolina Giuseppi, Sandra Kreitz, Veronika Pozharskaya, Karen L. Keeperman, Shelonitda Rose, Jeevan K. Shetty, Sheida Hayati, Sadanand Vodala, Andrius Degulys, Stefania Paolini, Thomas Cluzeau, and Guillermo Garcia-Manero

Subjects
Diseases of the blood and blood-forming organs, RC633-647.5
Published
2023
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