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Your search keyword '"Adrian Van Bakel"' showing total 4 results
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4 results on '"Adrian Van Bakel"'

1. INFLUENCE OF LOW VERSUS HIGH DOSE ON THE ASSOCIATION OF LOOP DIURECTIC AND MORTALITY IN PATIENTS WITH HEART FAILURE: INSIGHTS FROM THE UNITE-HF REGISTRY

Author

Kirkwood F. Adams, Adrian Van Bakel, Hector Ventura, Todd A. Schwartz, Ileana L. Piña, J. Herbert Patterson, Frank McGrew, Ron M. Oren, Amanda Lee, and Stephanie H. Dunlap

Subjects
medicine.medical_specialty, business.industry, medicine.drug_class, Loop diuretic, medicine.disease, Loop (topology), Heart failure, Internal medicine, Cardiology, medicine, High doses, In patient, Cardiology and Cardiovascular Medicine, business
Abstract

Background: Loop diuretics are associated with a dose-related increase in mortality in patients (Pts) with heart failure (HF) but less is known about the pattern of this relationship. Methods: The relationship between low and high doses of loop diuretic and mortality was investigated in the UNITE

Published
2017
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2. BETA-1 ADRENERGIC RECEPTOR GENOTYPE SER49GLY IS ASSOCIATED WITH BETA-BLOCKER SURVIVAL BENEFIT IN PATIENTS WITH HEART FAILURE

Author

Jalal K. Ghali, Kirkwood F. Adams, Ron M. Oren, J. Herbert Patterson, Jasmine A. Talameh, Alan B. Miller, Amanda K. Garrand, Carla A. Sueta, Stephanie H. Dunlap, Todd A. Schwartz, Ileana L. Piña, Adrian Van Bakel, and Frank McGrew

Subjects
medicine.medical_specialty, Adrenergic receptor, business.industry, medicine.drug_class, Single-nucleotide polymorphism, medicine.disease, Beta-1 adrenergic receptor, Internal medicine, Heart failure, Genotype, medicine, Cardiology, In patient, Cardiology and Cardiovascular Medicine, business, Receptor, Beta blocker
Abstract

Although beta-blockers (BB) reduce mortality in patients (Pts) with heart failure (HF), genetic differences in neurohormonal activation may limit effectiveness. Systematic review identified 3 adrenergic receptor SNPs as primary candidates. We report on the beta-1 receptor Gly49 variant that results

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