15 results on '"Altuncı, Yusuf Ali"'
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2. Evaluation of factors affecting the success of non invasive mechanical ventilation in acute cardiogenic pulmonary edema in the emergency department.
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Urgancı, Özge Akdemir, Altuncı, Yusuf Ali, Uz, İlhan, and Akarca, Funda Karbek
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SYSTOLIC blood pressure , *PULMONARY edema , *OXYGEN saturation , *BLOOD gases , *NONINVASIVE ventilation - Abstract
OBJECTIVES: The aim of this study was to evaluate the factors associated with non-invasive mechanical ventilation (NIMV) failure in acute cardiogenic pulmonary edema (ACPE) diagnosed in the emergency department. METHODS: This study was prospectively conducted at the Ege University Faculty of Medicine ED between February 19, 2021 and December 01, 2021. Patients who received NIMV with ACPE were included. Patients' clinical and laboratory parameters, treatments, NIMV mode, and settings were recorded. The primary endpoint was NIMV failure (intubation within 24 h). Secondary endpoints were early NIMV failure, early mortality (within 24 h), and in-hospital mortality. Early NIMV failure was defined as follows: if the patient had a respiratory rate of more than 25 per minute, oxygen saturation below 90%, PaCO2 >50 mmHg in blood gas, and pH <7.35, 1 h after starting NIMV. RESULTS: Out of 347 patients in this study, 34 (10.7%) of them intubated within 24 h. Female sex percentage was 48.7%. Median age was 73 years. Risk factors for NIMV failure were respiratory rate >40.5, systolic blood pressure <122.5 mmHg, Glasgow Coma Score <14, pH <7.21, lactate level >5.2 mmol/L, base excess <−4.5 mmol/L, B-type natriuretic peptide level >3007 pg/mL (respectively area under the curve values; 0.723, 0.693, 0.739, 0.721, 0.690, 0.698, and 0.616). CONCLUSION: Signs of hypoperfusion such as low systolic blood pressure (<122.5 mmHg) and high lactate (lactate level >5.2 mmol/L) are risk factors for NIMV failure. Evaluation of initial vital signs and arterial blood gas parameters is significantly important for prediction of NIMV success in ED. [ABSTRACT FROM AUTHOR]
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- 2025
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3. The Efficiency of Focused Assessment with Sonography for Trauma in Pediatric Patients with Blunt Torso Trauma
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Inci, Ozlem, primary, Altuncı, Yusuf Ali, additional, Can, Ozge, additional, Akarca, Funda Karbek, additional, and Ersel, Murat, additional
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- 2023
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4. Social media, FOAMed in medical education and knowledge sharing: Local experiences with international perspective
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Cevik, Arif Alper, Aksel, Gokhan, Akoglu, Haldun, Eroglu, Serkan Emre, Dogan, Nurettin Ozgur, and Altunci, Yusuf Ali
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- 2016
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5. The Efficiency of Focused Assessment with Sonography for Trauma in Pediatric Patients with Blunt Torso Trauma.
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Inci, Ozlem, Altuncı, Yusuf Ali, Can, Ozge, Akarca, Funda Karbek, and Ersel, Murat
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WOUNDS & injuries , *BLUNT trauma , *PATIENTS , *COMPUTED tomography , *SCIENTIFIC observation , *HOSPITAL admission & discharge , *FISHER exact test , *LOGISTIC regression analysis , *RETROSPECTIVE studies , *HOSPITAL emergency services , *CHI-squared test , *ABDOMINAL injuries , *TORSO , *SENSITIVITY & specificity (Statistics) , *EVALUATION , *ADOLESCENCE , *CHILDREN - Abstract
Introduction: Focused Assessment with Sonography for Trauma (FAST) has attracted attention for its use in the detection of intra-abdominal pathology for pediatric patients. However, computed tomography (CT) remains the gold standard for the assessment of blunt torso trauma. The study examines the effectiveness of FAST both in the detection of intra-abdominal pathology in pediatric patients (<19 years) with blunt torso trauma and in the determination of the need for CT for further examination. Methods: The study was designed as a retrospective observational investigation of diagnostic value. The pediatric patients who were admitted to the Emergency Department with blunt torso trauma between January 2013 and October 2016 were included in the study. The sample of the study comprised 255 patients who met the inclusion criteria. The primary outcome was the effectiveness of FAST in the detection of intra-abdominal pathology and the determination of the need for CT. The secondary outcome was to identify the agreement between CT and FAST for intra-abdominal injuries. The Chi-square test and Fisher's exact test were used for comparisons. A logistic regression model was developed to determine the variables that independently affect the agreement between FAST and CT. Results: FAST was determined to have low sensitivity (20.3%) despite its high specificity (87%). However; FAST had a good negative likelihood ratio. There was a poor agreement between CT and FAST in terms of the presence of both intra-abdominal and intrathoracic injuries in pediatric patients with blunt trunk trauma. The error rate of FAST increased by five-fold, especially in the presence of concomitant thorax trauma. However, FAST had a good negative likelihood ratio. Conclusion: FAST should not be regarded as an equivalent tool to CT for pediatric patients with blunt torso trauma. It is, instead, a noteworthy complementary tool that is a negative predictor. [ABSTRACT FROM AUTHOR]
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- 2024
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6. New Psychoactive Substance 5-MeO-MIPT In vivo Acute Toxicity and Hystotoxicological Study
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Altuncı, Yusuf Ali, primary, Aydoğdu, Melike, additional, Açıkgöz, Eda, additional, Güven, Ümmü, additional, Duzağa, Fahriye, additional, Atasoy, Aslı, additional, Dağlıoğlu, Nebile, additional, and Annette Akgür, Serap, additional
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- 2020
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7. Computed tomography vs. magnetic resonanceimaging in unstable cervical spine injuries
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Biçeroğlu, Hüseyin, Kitiş, Ömer, Eraslan, Cenk, Akay, Ali Ferruh, Altuncı, Yusuf Ali, and Kodik, Meltem Songür
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BACKGROUND:This study aimed to investigate the role of computed tomography (CT) in identifying missed unstable blunt cer-vical injuries.METHODS:Patients admitted to the emergency department between June 2014 and June 2018 with a diagnosis of blunt cervical trauma were included in this study. All participants underwent cervical magnetic resonance imaging (MRI) after an initial cervical CT investigation. All imaging results were reviewed, and decisions were taken by the consensus of a team consisting of an emergency medicine specialist, a neuroradiologist, and a neurosurgeon. Other variables included age, sex, the Glasgow Coma Scale, medical comorbidities, multi-trauma, neurological deficits, accompanying intracranial hemorrhage, extremity fractures, and the mechanism of the injury.RESULTS:Data for 195 patients were analyzed. The mean (±standard deviation) age of the participants was 47.34±21.90 years, and 140 (71.8%) were males. Eighteen patients (9.2%) were below age
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- 2020
8. Seasonal variations of patients presenting dyspnea to emergency departments in Europe: Results from the EURODEM Study
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UCL - SSS/IREC/MEDA - Pôle de médecine aiguë, UCL - (SLuc) Service des urgences, Karamercan, Mehmet Akif, Dündar, Zerrin Defne, Ergin, Mehmet, VAN Meer, Oene, Body, Richard, Harjola, Veli-Pekka, Verschuren, Franck, Christ, Micheal, Golea, Adela, Capsec, Jean, Barletta, Cinzia, Garcia-Castrillo, Luis, Altuncı, Yusuf Ali, Katırcı, Yavuz, Kelly, Anne-Maree, Laribi, Said, UCL - SSS/IREC/MEDA - Pôle de médecine aiguë, UCL - (SLuc) Service des urgences, Karamercan, Mehmet Akif, Dündar, Zerrin Defne, Ergin, Mehmet, VAN Meer, Oene, Body, Richard, Harjola, Veli-Pekka, Verschuren, Franck, Christ, Micheal, Golea, Adela, Capsec, Jean, Barletta, Cinzia, Garcia-Castrillo, Luis, Altuncı, Yusuf Ali, Katırcı, Yavuz, Kelly, Anne-Maree, and Laribi, Said
- Abstract
BACKGROUND/AIM: To describe seasonal variations in epidemiology, management, and short-term outcomes of patients in Europe presenting to an emergency department (ED) with a main complaint of dyspnea. MATERIALS AND METHODS: Anobservational prospective cohort study was performed in 66 European EDs which included consecutive patients presenting to EDs with dyspnea as the main complaint during 3 72-h study periods. Data were collected on demographics, comorbidities, chronic treatment, prehospital treatment, mode of arrival of patient to ED, clinical signs at admission, treatment in the ED, ED diagnosis, discharge from ED, and in-hospital outcome. RESULTS: The study included 2524 patients with a median age of 69 (53–80) years old. Of the patients presented, 991 (39.3%) were in autumn, 849 (33.6%) were in spring, and 48 (27.1%) were in winter. The winter population was significantly older (P < 0.001) and had a lower rate of ambulance arrival to ED (P < 0.001). In the winter period, there was a higher rate for lower respiratory tract infection (35.1%), and patients were more hypertensive, more hypoxic, and more hyper/hypothermic compared to other seasons. The ED mortality was about 1% and, in hospital, mortality for admitted patients was 7.4%. CONCLUSION: The analytic method and the outcome of this study may help to guide the allocation of ED resources more efficiently and to recommend seasonal ED management protocols based on the seasonal trend of dyspneic patients.
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- 2020
9. New Psychoactive Substance 5-MeO-MiPT In vivo Acute Toxicity and Hystotoxicological Study.
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Altuncı, Yusuf Ali, Aydoğdu, Melike, Açıkgöz, Eda, Güven, Ümmü, Düzağaç, Fahriye, Atasoy, Aslı, Dağlıoğlu, Nebile, and Akgür, Serap Annette
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BLOOD testing , *TISSUE analysis , *ANIMAL experimentation , *CELL lines , *CELL surface antigens , *HISTOLOGY , *IMMUNODIAGNOSIS , *IMMUNOHISTOCHEMISTRY , *MICE , *ORGANS (Anatomy) , *PSYCHIATRIC drugs , *STAINS & staining (Microscopy) , *TOXICOLOGY , *TRYPTAMINE , *QUANTITATIVE research , *DESCRIPTIVE statistics , *IN vivo studies - Abstract
Background: The hallucinogenic tryptamine analog 5-methoxy-N-methyl-N-isopropyltryptamine (5-MeO-MiPT) causes social problems worldwide. There are several studies on the metabolism; however, not more studies were found in the literature on acute toxicity. Aims: To report the acute toxicity of 5-MeO-MiPT in mice, followed by quantitative toxicological analysis of blood and organs, hystotoxicological and immunohistochemical analysis of tissues and cells. Study design: Animal experiment Methods: In vivo experiments were performed using CDl adult female mice (n=26). Animals were caged in 4 groups randomly. First group was a control (n=3). Second group was vehicle control (n=3) and injected 150 µL of blank solution (50% dimethyl sulfoxide in saline /0.9% of NaCl). While for acute toxicity experiments, 5-MeO-MiPT was added to a blank solution in order to obtain a dose of 0.27 mg/kg in 150 µL injection (n=10) and the last group were injected 2.7 mg/kg 5-MeO- MiPT in a 150 µL injection (n=10). Quantitative toxicological analysis, hystotoxicological and immunohistochemical analysis were performed. Results: In the toxicological analysis, 5-MeO-MiPT was found negative in biological samples which were control, vehicle control, and 0.27 mg/kg dose mice groups. 5-MeO-MiPT was found 2.7-13.4 ng/ mL in blood, 11-29 ng/g in kidney, 15.2-108.3 ng/g in liver, and 1.540.6 ng/g in the brain in 2,7 mg/kg injected group. In a low dose of the 5-MeO-MiPT liver section, compared with normal tissues, the difference in staining was statistically significant (p<0.0001). In highdose of 5-MeO-MiPT, H-score showed that the increase in the number of Caspase-3 positive cells was significant compared to the control (p<0.05). In high-dose of 5-MeO-MiPT, intense Caspase-3 immunore-activity was observed and the increase in the number of Caspase-3 positive cells compared to the control was statistically significant (p<0.05). In brain section, the statistics of the results obtained from the H-score showed that the increase in the number of Caspase-3 positive cells was significant compared to the control (p=0.0183). In vehicle control liver section, there were few Caspase-8 positive cells characterized by a light brown appearance (p=0.0117). In the high-dose 5-MeO-MiPT group, the numbers of positive cells at low and high doses of 5-MeO-MiPT group were statistically significant compared to the control (p<0.05). In the high-dose 5-MeO-MiPT group, Caspase-8 immunoreactivity was detected in the glomerular structures. Compared to control, the increase in Caspase-8 immunoreactivity was found to be statistically significant (p<0.05). Conclusion: Low-dose 5-MeO-MiPT did not cause any serious histo-pathological effects on the liver, kidney, and brain. High doses induce apoptotic cell death through caspase activity. [ABSTRACT FROM AUTHOR]
- Published
- 2021
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10. Künt multitravma hastalarında acil gözlemin; hastaneye yatış ve mortalite üzerine etkisi (Retrospektif çalışma)
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Altuncı, Yusuf Ali, Aldemir, Mustafa, Dicle Üniversitesi, Tıp Fakültesi, Acil Tıp Anabilim Dalı, and Altuncı, Yusuf Ali
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Travma ,Acil tedavi ,Acil servis ,Emergency treatment ,Mortality ,Trauma ,Emergency service ,Mortalite - Abstract
Günümüzde travma, sosyoekonomik gelişmişliğe bakmaksızın her ülkede temel halk sağlığı problemlerinden biridir. İleri yaş grubundaki insanlar, genç insanlardan daha az oranda travmaya maruz kalmalarına rağmen, ölüm oranları ileri yaş grubundaki insanlarda daha yüksektir. Bununla beraber, 15 –24 yaş arasındakilerin, tüm ölümlerin % 78’i travmadan dolayıdır. Üçüncü basamak tedavi merkezi olan hastanemizin acil servisine bölgemizdeki travma hastaları başvurmaktadır. Amacımız künt multi travma yaralanma mekanizmaları ile başvuran hastalarımızın acil servis gözlem odası veya hastaneye yattıktan sonra yapılan takiplerinin gözden geçirilmesi ve günümüz konservatif yaklaşımlarına ne kadar paralellik gösterebildiğidir. Çalışmamızda Ocak 2006 ile Ocak 2008 tarihleri arasında yüksekten düşme, araç içi ve araç dışı trafik kazası, iş kazası, darp gibi künt multi travma nedeniyle Dicle Üniversitesi Hastanesi Acil Servisine başvuran, medikal kayıtlarına ulaşılabilen ve belirtilen kriterleri tam olarak bulunan 15 yaş üstü 226 hastaya ait veri geriye dönük olarak analiz edildi. İstatistiksel verilerin hazırlanmasında; hastalar acil serviste gözlenenler (n=105) ve hastaneye yatırılanlar (n=121) olmak üzere iki gruba ayrıldı. Çalışmaya alınan 226 hastanın %71.7’si (n=162) erkek, %28.3’ü (n=64) kadındı. Travmaya maruz kalan 226 hastanın 19’u (%8.4) ex oldu. Ortalama yaş tüm hastalar için 35.9±15.882 (15 -94) idi. Acil serviste yapılan kan transfüzyonunun hastaneye yatışta anlamlı olduğu görülmüştür (p=0.00). Hastanın acil gözlem ya da hastaned e yatış karşılaştırmalarında ALT, AST, HTC ve beyaz küre değerlerinin kullanılabilirliği istatistiksel olarak belirleyici olmuştur (p0.05). Injury Severity Score and Abbreviated Injury Scale (AIS) were available for group 2 patients scientifically (p
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- 2008
11. Cam kesiğine bağlı el ve el bileği yaralanmaları: kaza veya ani öfke?
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Gökhan, Şervan, Altuncı, Yusuf Ali, Orak, Murat, Üstündağ, Mehmet, Söğüt, Özgür, Özhasenekler, Ayhan, and Ege Üniversitesi
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Cerrahi - Abstract
AmaçTravmatik el ve el bileği yaralanmaları acil serviste yaygın görülen yaralanmalardır. Ani öfkelenmeye bağlı cama yumruk atma ile ilişkili el ve el bileği yaralanmaları ülkemizde sıktır. Bu çalışmanın amacı oluş nedenlerine göre cam kesisi ile ilişkili el ve el bileği yaralanmalı hastalarda klinik ve demografik özellikleri analiz etmektir.Gereç ve YöntemDicle Üniversitesi Tıp Fakültesi Acil Servisi’ne cam kesisine bağlı yaralanma nedeniyle başvuran hastalar çalışmaya dahil edildi. Hastaların demografik verileri standart çalışma formuna kaydedildi. Demografik veriler istatistiksel olarak analiz edildi.BulgularÇalışmaya 154 hasta dahil edildi. Hastaların %53.8’I ani sinirlenmeye bağlı olarak cama yumruk atan hastalardı. Cama yumruk atma erkeklerde daha sık gözlendi (n=81, %97.6), yumruk atan grupta sağ el yaralanması daha sık görüldü (n=65, %78.3). Cama yumruk atma ile ilişkili yaralanmalı 24 hasta (%28.9) alkollüydü ve bu hastalarda radial arter, ulnar sinir, median sinir ve ulnar arter yaralanması anlamlı düzeyde yüksek bulundu.SonuçEl ve el bileği yaralanması nedeniyle acil servise başvuran hastaların damar, sinir ve tendon muayenelerinin dikkatli yapılması, özellikle alkollü hastalarda bu anatomik yapıların yaralanmalarının birlikte olabileceği, sonrasında ciddi fonksiyon kayıplarına yol açmaması için erken dönemde kontrollerinin yapılması sağlanmalıdır., ObjectivesTraumatic hand and wrist injuries are the type of injuries commonly seen in the emergency department (ED). Hand and wrist injuries related to punching windows due to sudden discomposes are frequent in Turkey. the aim of this study was to analyze clinical and demographic specifications of hand and wrist injuries related to glass cuts and their underlying causes.MethodsThe patient files who presented to the Dicle University Hospital ED (Diyarbakır-Turkey) with injuries due to glass cuts have been examined. Demographic data of the patients have been recorded in the standard work form and then were analyzed.ResultsOne hundred and fifty four patients were included in the study. 53.8% of the patients constituted those who punched on the glass during an angry episode. Punching on the glass was more frequently observed in men (n=81, 97.6%), with cuts to the right hand being the most frequent type of resulting injury (n=65, 78.3%). Twenty four (28.9%) of the patients with injuries related to glass punching were under the influence of alcohol during the incidents and injury rates of radial artery, ulnar nerve, median nerve and ulnar artery have been found considerably higher in this group.ConclusionsA thorough artery, nerve and tendon examination of the patients presenting to the ED with hand and wrist injuries needed to be performed, and especially for those under the influence of alcohol in order to prevent functional losses of the underlying structures.
- Published
- 2011
12. Nivolumab, a new immunomodulatory drug, a new adverse effect; adrenal crisis
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Akarca, Funda Karbek, Can, Ozge, Yalcinli, Sercan, and Altunci, Yusuf Ali
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- 2017
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13. Künt gövde travması nedeniyle acil servise başvurmuş pediatrik hastalarda odaklanmış travma ultrasonografisinin (OTU) hasta yönetimine etkisinin retrospektif olarak değerlendirilmesi
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İnci, Özlem, Altuncı, Yusuf Ali, and Acil Tıp Anabilim Dalı
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Retrospective studies ,Radiography ,Wounds-nonpenetrating ,Wounds and injuries ,İlk ve Acil Yardım ,Emergency medicine ,Children ,Emergency and First Aid ,Emergency service-hospital ,Ultrasonography - Abstract
Künt gövde travması sık görülen bir yaralanmadır. Toraks ve batın içi yaralanmaları pediatrik morbidite ve mortaliteye sebep olduğundan çoğu merkezde odaklanmış travma ultrasonu(OTU) kullanımı bilgisayarlı tomografi (BT)'nin önceliğinin yerini almıştır. Acil servislerde travma hastalarına yaklaşımda OTU görüntüleme açısından ilk sırada uygulanabilir. Hastanın travma mekanizması göz önünde bulundurularak klinik şüphe halinde BT ileri tetkik için ikinci yaklaşım olmalıdır. OTU ile BT'nin birlikte kullanımı batın içi yaralanma şüphesi olan hastalarda tanı olasılığını arttırır. Fakat düşük ya da orta risk varsa ve OTU bu sonuçları destekliyorsa BT ile sonuç doğrulanmalıdır. Bu çalışmada; tanı amaçlı uygulanmış olan ve hızlı ve radyasyon riski az olan OTU'nun batın içi patolojiyi saptamada ve BT ihtiyacını belirlemedeki etkinliğini araştırmaktır. Blunt trunk trauma is a common injury. thoracic and abdominal injuries cause pediatric morbidity and mortality. The use of focused assessment with sonography in trauma (fast) in most centers has taken precedence over computerized tomography (CT). In the approach to trauma patients in emergency services, FAST can be applied in the first order in terms of imaging. In case of clinical suspicion, CT should be the second approach for advanced examination considering the trauma mechanism of the patient. The combined use of FAST and CT increases the likelihood of diagnosis in patients with suspected intrauterine injury. However, if there is a low or moderate risk and OTU supports these results, the outcome should be confirmed with CT. In our study; to investigate the efficacy of detecting intrauterine intra-abdominal pathology and determining the need for CT, which has been used for diagnostic purposes and has a rapid and low radiation risk. 73
- Published
- 2018
14. Üst gastrointestinal kanama nedeniyle acil servise başvuran hastalarda AİMS65, glascow blatchford ve erken rockall skorlamalarının taburculuk ve mortalite üzerine etkisinin ileriye yönelik araştırılması
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Bulandere, Nihat, Altuncı, Yusuf Ali, and Acil Tıp Anabilim Dalı
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Patient discharge ,Erythrocyte transfusion ,İlk ve Acil Yardım ,Scales ,Hemorrhage ,Mortality ,Gastrointestinal hemorrhage ,Emergency service ,Emergency and First Aid - Abstract
Giriş:Üst gastrointestinal sistem kanamaları yaklaşık %10 mortalite değerine sahip, uzun yatış süresi ve, bakım maliyetleri olan sık görülen acil bir durumdur. Mortalitesi bu kadar yüksek olan medikal bir acil duruma erken endoskopi yapmak, erken cerrahi/girişimsel radyolojik işlem yapmak, yoğun bakım gibi bakım ve tedavi seviyesini erken belirlemek önemlidir. Bu çalışmada amacımız literatürde acil serviste az yapılmış olan acil servis izlemindeki hastada Glaskow Blatchford (GBS), Erken Rockall ile hatırlanması ve hesaplanması daha kolay olan AİMS65 skorlama sistemlerinin taburculuk/yatış, eritrosit transfüzyon gereksinimi, tekrar kanama ve mortaliteyi öngörmedeki başarılarını kıyaslamaktır.Yöntem:Çalışmamız prospektif gözlemsel tanısal değerlilik olarak tasarlanandı. Ege Üniversitesi Tıp Fakiltesi Hastanesi Acil Servis'İne Ağustos/2016 –Ocak/2017 tarihleri arasında başvuran, çalışmaya alınma kriterlerini karşılayan 181 olgu değerlendirildi. Tüm skorlar her hasta için ayrı ayrı hesaplandı. Risk skorlarının karşılaştırılırken karar vericinin etkinlik eğrisi (ROC) her skor için düzenlenerek primer ve sekonder sonlanım ilişkileri değerlendirildi. Mortalite, yeniden kanama, eritrosit transfüzyon ihtiyacı ve hastaneye yatış gibi sonlanımlar için her skor sisteminin maksimum sensitivite ve spesifiteye göre cut-off değeri belirlendi. Veriler gruplandırıldı ve kategorik değişkenlerin karşılaştırılması pearson's ki-kare testi ile yapıldı. Sonuç:Çalışmamızda 40 hastanın yatırılarak tedavi edildiği, 97 hastaya eritrosit transfüzyonu yapıldığı belirlendi. Hastalarımızın 30'unda bir ay içerinde mortalite görüldü. Tekrar kanayan hasta sayısı ise 29 hastada 1 ay içinde görüldü. Yüksek riskli hastayı belirlemede GBS skor sisteminin (AUC:0,824) ERS(AUC: 0,691 ) ve AİMS65'den(AUC:0,612) üstün olduğu saptandı (p
- Published
- 2017
15. Seasonal variations of patients presenting dyspnea to emergency departments in Europe: Results from the EURODEM Study
- Author
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Karamercan MA, Dündar ZD, Ergin M, VAN Meer O, Body R, Harjola VP, Verschuren F, Christ M, Golea A, Capsec J, Barletta C, Garcia-Castrillo L, Altuncı YA, Katırcı Y, Kelly AM, and Laribi S
- Subjects
- Age Factors, Aged, Aged, 80 and over, Ambulances statistics & numerical data, Anti-Bacterial Agents therapeutic use, Bronchodilator Agents therapeutic use, Cohort Studies, Comorbidity, Diuretics therapeutic use, Dyspnea physiopathology, Europe epidemiology, Female, Hospitalization statistics & numerical data, Humans, Male, Middle Aged, Oxygen Inhalation Therapy methods, Prospective Studies, Dyspnea epidemiology, Dyspnea therapy, Emergency Service, Hospital, Seasons
- Abstract
Background/aim: To describe seasonal variations in epidemiology, management, and short-term outcomes of patients in Europe presenting to an emergency department (ED) with a main complaint of dyspnea., Materials and Methods: Anobservational prospective cohort study was performed in 66 European EDs which included consecutive patients presenting to EDs with dyspnea as the main complaint during 3 72-h study periods. Data were collected on demographics, comorbidities, chronic treatment, prehospital treatment, mode of arrival of patient to ED, clinical signs at admission, treatment in the ED, ED diagnosis, discharge from ED, and in-hospital outcome., Results: The study included 2524 patients with a median age of 69 (53–80) years old. Of the patients presented, 991 (39.3%) were in autumn, 849 (33.6%) were in spring, and 48 (27.1%) were in winter. The winter population was significantly older (P < 0.001) and had a lower rate of ambulance arrival to ED (P < 0.001). In the winter period, there was a higher rate for lower respiratory tract infection (35.1%), and patients were more hypertensive, more hypoxic, and more hyper/hypothermic compared to other seasons. The ED mortality was about 1% and, in hospital, mortality for admitted patients was 7.4%., Conclusion: The analytic method and the outcome of this study may help to guide the allocation of ED resources more efficiently and to recommend seasonal ED management protocols based on the seasonal trend of dyspneic patients., Competing Interests: none declared, (This work is licensed under a Creative Commons Attribution 4.0 International License.)
- Published
- 2020
- Full Text
- View/download PDF
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