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1. Bioprofiling TS/A Murine Mammary Cancer for a Functional Precision Experimental Model.

Author

De Giovanni, Carla, Nicoletti, Giordano, Landuzzi, Lorena, Palladini, Arianna, Lollini, Pier-Luigi, and Nanni, Patrizia

Subjects
BREAST tumors, CELL lines, GENE therapy, GENETIC techniques, MATHEMATICAL models, MICE, TUMOR markers, THEORY
Abstract

The TS/A cell line was established in 1983 from a spontaneous mammary tumor arisen in an inbred BALB/c female mouse. Its features (heterogeneity, low immunogenicity and metastatic ability) rendered the TS/A cell line suitable as a preclinical model for studies on tumor–host interactions and for gene therapy approaches. The integrated biological profile of TS/A resulting from the review of the literature could be a path towards the description of a precision experimental model of mammary cancer. [ABSTRACT FROM AUTHOR]

Published
2019
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