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Your search keyword '"Ben-Haroush Schyr, Rachel"' showing total 13 results
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13 results on '"Ben-Haroush Schyr, Rachel"'

4. Mapping the metabolic reprogramming induced by sodium-glucose cotransporter 2 inhibition

Author

Kogot-Levin, Aviram, primary, Riahi, Yael, additional, Abramovich, Ifat, additional, Mosenzon, Ofri, additional, Agranovich, Bella, additional, Kadosh, Liat, additional, Ben-Haroush Schyr, Rachel, additional, Kleiman, Doron, additional, Hinden, Liad, additional, Cerasi, Erol, additional, Ben-Zvi, Danny, additional, Bernal-Mizrachi, Ernesto, additional, Tam, Joseph, additional, Gottlieb, Eyal, additional, and Leibowitz, Gil, additional

Published
2023
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5. Sleeve Gastrectomy Reduces Glycemia but Does Not Affect Cognitive Impairment in Lean 5xFAD Mice

Author

Samuel, Itia, primary, Ben-Haroush Schyr, Rachel, additional, Arad, Yhara, additional, Attali, Tamar, additional, Azulai, Shira, additional, Bergel, Michael, additional, Halfon, Aviv, additional, Hefetz, Liron, additional, Hirsch, Tamir, additional, Israeli, Hadar, additional, Lax, Neta, additional, Nitzan, Keren, additional, Sender, Dana, additional, Sweetat, Sahar, additional, Okun, Eitan, additional, Rosenmann, Hanna, additional, and Ben-Zvi, Danny, additional

Published
2022
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6. Maternal antagonism of Glp1 reverses the adverse outcomes of sleeve gastrectomy on mouse offspring

Author

Hefetz, Liron, primary, Ben-Haroush Schyr, Rachel, additional, Bergel, Michael, additional, Arad, Yhara, additional, Kleiman, Doron, additional, Israeli, Hadar, additional, Samuel, Itia, additional, Azulai, Shira, additional, Haran, Arnon, additional, Levy, Yovel, additional, Sender, Dana, additional, Rottenstreich, Amihai, additional, and Ben-Zvi, Danny, additional

Published
2022
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7. Generation and characterization of a mouse model for one anastomosis gastric bypass surgery

Author

Abu-Gazala, Samir, primary, Bergel, Michael, additional, Arad, Yhara, additional, Hefetz, Liron, additional, Azulai, Shira, additional, Baker, Aaron, additional, Haran, Arnon, additional, Israeli, Hadar, additional, Kleiman, Doron, additional, Samuel, Itia, additional, Tsubary, Uria, additional, Permyakova, Anna, additional, Tam, Joseph, additional, Ben-Haroush Schyr, Rachel, additional, and Ben-Zvi, Danny, additional

Published
2022
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8. Sleeve Gastrectomy Suppresses Hepatic Glucose Production and Increases Hepatic Insulin Clearance Independent of Weight Loss

Author

Ben-Haroush Schyr, Rachel, primary, Al-Kurd, Abbas, additional, Moalem, Botros, additional, Permyakova, Anna, additional, Israeli, Hadar, additional, Bardugo, Aya, additional, Arad, Yhara, additional, Hefetz, Liron, additional, Bergel, Michael, additional, Haran, Arnon, additional, Azar, Shahar, additional, Magenheim, Itia, additional, Tam, Joseph, additional, Grinbaum, Ronit, additional, and Ben-Zvi, Danny, additional

Published
2021
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13. Generation and characterization of a mouse model for one anastomosis gastric bypass surgery.

Author

Abu-Gazala S, Bergel M, Arad Y, Hefetz L, Azulai S, Baker A, Haran A, Israeli H, Kleiman D, Samuel I, Tsubary U, Permyakova A, Tam J, Ben-Haroush Schyr R, and Ben-Zvi D

Subjects
Animals, Disease Models, Animal, Humans, Mice, Retrospective Studies, Weight Loss physiology, Bariatric Surgery methods, Gastric Bypass methods, Insulin Resistance, Obesity, Morbid metabolism
Abstract

One anastomosis gastric bypass (OAGB) surgery became a common bariatric procedure in recent years. In this surgery, the distal stomach, duodenum, and proximal jejunum are bypassed, leading to weight loss, improvement in metabolic parameters, and a change in hormonal secretion. We sought to generate and characterize a mouse model for OAGB. Mice fed for 26 wk on a high-fat diet were assigned to OAGB, sham surgery, or caloric restriction and were followed for 50 more days on a high-fat diet. Physiological and histological parameters of the mice were compared during and at the end of the experiment. OAGB-operated mice lost weight and displayed low levels of plasma lipids, high insulin sensitivity, and rapid glucose metabolism compared with sham-operated mice. OAGB-operated mice had higher energy expenditure, higher levels of glucagon-like peptide (GLP-1), and lower albumin than weight-matched calorie-restricted mice. There was no difference in the histology of the endocrine pancreas. The livers of OAGB mice had little hepatic steatosis yet presented with a large number of phagocytic cells. The OAGB mouse model recapitulates many of the phenotypes described in patients that underwent OAGB and enables molecular and physiological studies on the outcome of this surgery. NEW & NOTEWORTHY A mouse model for one anastomosis gastric bypass (OAGB) surgery displays similar outcomes to clinical reports and enables to study the weight loss-dependent and -independent effects of this bariatric surgery.

Published
2022
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