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10. Childbirth Pain, Labor Epidural Analgesia, and Postpartum Depression: Recent Evidence and Future Directions

Author

Du,Weijia, Bo,Lulong, Xu,Zhendong, and Liu,Zhiqiang

Subjects
Journal of Pain Research
Abstract

Weijia Du1 *, Lulong Bo2 *, Zhendong Xu,1 Zhiqiang Liu1 1Department of Anesthesiology, Shanghai Key Laboratory of Maternal Fetal Medicine, Shanghai Institute of Maternal-Fetal Medicine and Gynecologic Oncology, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, People’s Republic of China; 2Faculty of Anesthesiology, Changhai Hospital, Naval Medical University, Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhiqiang Liu; Zhendong Xu, Department of Anesthesiology, Shanghai Key Laboratory of Maternal Fetal Medicine, Shanghai Institute of Maternal-Fetal Medicine and Gynecologic Oncology, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, 200092, People’s Republic of China, Tel +86 13816877756 ; +86 13817029904, Email drliuzhiqiang@163.com; btxzd123@126.comAbstract: Pregnancy and childbirth are major life events for women and their families, characterized by physical, psychological, and emotional changes that can trigger anxiety, depression, and mental disorders in susceptible individuals. Acute labor pain is an independent risk factor for persistent pain in the postpartum period and is associated with depressive disorders. Epidural analgesia is a well-established technique that has commonly been regarded as the gold standard in pain management during labor. Although the relationships between labor pain, labor epidural analgesia, and postpartum depression have been studied by many investigators, the results of these studies are conflicting. Some literature suggest that labor epidural analgesia is associated with a reduction in the incidence of postpartum depression; however, other studies have failed to demonstrate this association. Unmet analgesic needs expectations, unmet birth expectations, and/or the quality of social support during labor may contribute to postpartum depression. The limitations of the published studies included differential misclassification of study variables and residual confounding, variations in the diagnosis of depression, and incomplete history data. Thus, future studies should include information on sociodemographic and patient-level variables and assessments of pain during labor or in the postpartum period. Better management of labor pain should be provided to prevent long-term morbidity and improve maternal and neonatal outcomes. Anesthesiologists could collaboratively work with obstetricians and perinatal psychiatrists to ensure that hospitals prioritize screening and treatment for postpartum depression.Keywords: epidural labor analgesia, labor pain, neuraxial analgesia, postpartum depressive disorder, pain management in labor

Published
2022

18. Effect of Perioperative Intravenous Lidocaine on Postoperative Recovery in Patients Undergoing Ileostomy Closure: Study Protocol for a Randomized Controlled Trial

Author

Liu,Jia, Liu,Kun, Wang,Huixian, Hu,Hongli, Sun,Guolin, Ye,Xiaofei, Lou,Zheng, Bian,Jinjun, Bo,Lulong, Liu,Jia, Liu,Kun, Wang,Huixian, Hu,Hongli, Sun,Guolin, Ye,Xiaofei, Lou,Zheng, Bian,Jinjun, and Bo,Lulong

Abstract

Jia Liu,1,* Kun Liu,1,* Huixian Wang,1,* Hongli Hu,1 Guolin Sun,1 Xiaofei Ye,2 Zheng Lou,3 Jinjun Bian,1 Lulong Bo1 1Faculty of Anesthesiology, Changhai Hospital, Naval Medical University, Shanghai, People’s Republic of China; 2Department of Health Statistics, Naval Medical University, Shanghai, People’s Republic of China; 3Department of Colorectal Surgery, Changhai Hospital, Naval Medical University, Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Lulong Bo; Jinjun Bian, Faculty of Anaesthesiology, Changhai Hospital, Naval Medical University, Shanghai, 200433, People’s Republic of China, Tel +86-2131161839, Email bartbo@smmu.edu.cn; jinjunbicu@163.comIntroduction: Opioids have been widely used clinically as the first choice for pain management. Ileostomy closure usually leads to temporary intestinal paralysis, which manifests as abdominal distension and pain, delayed defecation, nausea, and vomiting. Intraoperative and postoperative use of opioids inhibit gastrointestinal function and aggravate intestinal paralysis, and are notoriously addictive. Thus, reducing perioperative opioid use is important for patients undergoing ileostomy closure to restore the continuity and integrity of the intestine. Intravenous lidocaine has been shown to have anti-inflammatory properties and analgesic effects. We consider minimizing the use of opioids for such patients, and perioperative intravenous injection of lidocaine may be beneficial to the recovery of intestinal function in patients with ileostomy closure.Methods and Analysis: This is a randomized double-blind placebo-controlled trial to investigate the effectiveness and safety of intravenous lidocaine in patients undergoing ileostomy closure. The time of first postoperative anal venting, postoperative opioids use, postoperative recovery, intraoperative adverse effects and postoperative complications will be collected and analyzed.Keywor

Published
2022

21. Risk Factors for Delirium after Deep Brain Stimulation Surgery under Total Intravenous Anesthesia in Parkinson's Disease Patients.

Author

Lu, Wenbin, Chang, Xinning, Bo, Lulong, Qiu, Yiqing, Zhang, Mingyang, Wang, Jiali, Wu, Xi, and Yu, Xiya

Subjects
DEEP brain stimulation, PARKINSON'S disease, INTRAVENOUS anesthesia, BRAIN stimulation, BRAIN surgery, DELIRIUM, LOGISTIC regression analysis
Abstract

Background: Postoperative delirium (POD) is associated with perioperative complications and mortality. Data on the risk factors for delirium after subthalamic nucleus deep brain stimulation (STN-DBS) surgery is not clarified in Parkinson's disease (PD) patients receiving total intravenous anesthesia. We aimed to investigate the risk factors for delirium after STN-DBS surgery in PD patients. Methods:The retrospective cohort study was conducted, including 131 PD patients who underwent STN-DBS for the first time under total intravenous anesthesia from January to December 2021. Delirium assessments were performed twice daily for 7 days after surgery or until hospital discharge using the confusion assessment method for the intensive care unit. Multivariate logistic regression analysis was used to determine the risk factor of POD. Results: In total, 22 (16.8%) of 131 patients were in the POD group, while the other 109 patients were in the Non-POD group. Multivariate logistic regression analysis showed that preoperative Mini-mental State Examination score [odds ratio = 0.855, 95% confidence interval = 0.768–0.951, p = 0.004] and unified Parkinson's disease rating scale part 3 (on state) score (odds ratio = 1.061, 95% confidence interval = 1.02–1.104, p = 0.003) were independently associated with delirium after surgery. Conclusions: In this retrospective cohort study of PD patients, a lower Mini-mental State Examination score and a higher unified Parkinson's disease rating scale part 3 (on state) score were the independent risk factors for delirium after STN-DBS surgery in PD patients under total intravenous anesthesia. [ABSTRACT FROM AUTHOR]

Published
2023
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27. Additional file 1 of Extubation in the operating room results in fewer composite mechanical ventilation-related adverse outcomes in patients after liver transplantation: a retrospective cohort study

Author

Xu, Yan, Zuo, Yiding, Zhou, Li, Hao, Xuechao, Xiao, Xiao, Ye, Mao, Bo, Lulong, Jiang, Chunling, and Yang, Jiayin

Abstract

Additional file 1: Table S1. STROBE Statement. Checklist of our cohort study, which demonstrates STROBE Statement Checklist of our cohort study.

Published
2021
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28. Additional file 7 of Extubation in the operating room results in fewer composite mechanical ventilation-related adverse outcomes in patients after liver transplantation: a retrospective cohort study

Author

Xu, Yan, Zuo, Yiding, Zhou, Li, Hao, Xuechao, Xiao, Xiao, Ye, Mao, Bo, Lulong, Jiang, Chunling, and Yang, Jiayin

Abstract

Additional file 7: Figure S2 Association between extubation in the OR and composite mechanical ventilation-related adverse outcomes.

Published
2021
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29. Additional file 6 of Extubation in the operating room results in fewer composite mechanical ventilation-related adverse outcomes in patients after liver transplantation: a retrospective cohort study

Author

Xu, Yan, Zuo, Yiding, Zhou, Li, Hao, Xuechao, Xiao, Xiao, Ye, Mao, Bo, Lulong, Jiang, Chunling, and Yang, Jiayin

Abstract

Additional file 6: Table S5 Unplanned-Reintubation indications amongst OR extubation and ICU extubation groups after matching.

Published
2021
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30. Additional file 4 of Extubation in the operating room results in fewer composite mechanical ventilation-related adverse outcomes in patients after liver transplantation: a retrospective cohort study

Author

Xu, Yan, Zuo, Yiding, Zhou, Li, Hao, Xuechao, Xiao, Xiao, Ye, Mao, Bo, Lulong, Jiang, Chunling, and Yang, Jiayin

Subjects
body regions, nervous system, sense organs, equipment and supplies
Abstract

Additional file 4: Figure S1 Histograms of the estimated propensity scores.

Published
2021
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32. Additional file 3 of Extubation in the operating room results in fewer composite mechanical ventilation-related adverse outcomes in patients after liver transplantation: a retrospective cohort study

Author

Xu, Yan, Zuo, Yiding, Zhou, Li, Hao, Xuechao, Xiao, Xiao, Ye, Mao, Bo, Lulong, Jiang, Chunling, and Yang, Jiayin

Abstract

Additional file 3: Table S3 Predefined Postoperative Complications According European Perioperative Clinical Outcome definitions.

Published
2021
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33. Additional file 2 of Extubation in the operating room results in fewer composite mechanical ventilation-related adverse outcomes in patients after liver transplantation: a retrospective cohort study

Author

Xu, Yan, Zuo, Yiding, Zhou, Li, Hao, Xuechao, Xiao, Xiao, Ye, Mao, Bo, Lulong, Jiang, Chunling, and Yang, Jiayin

Subjects
urogenital system, urologic and male genital diseases
Abstract

Additional file 2: Table S2 Predefined Acute Kidney Injury (AKI) According Kidney Disease Improving Global Outcomes Guidelines (KIDGO).

Published
2021
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48. Baicalin Improves Survival in a Murine Model of Polymicrobial Sepsis via Suppressing Inflammatory Response and Lymphocyte Apoptosis

Author

Zhu, Jiali, primary, Wang, Jiafeng, additional, Sheng, Ying, additional, Zou, Yun, additional, Bo, Lulong, additional, Wang, Fei, additional, Lou, Jingsheng, additional, Fan, Xiaohua, additional, Bao, Rui, additional, Wu, Youping, additional, Chen, Feng, additional, Deng, Xiaoming, additional, and Li, Jinbao, additional

Published
2012
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