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3. Anxiety and its risk factors among non-Japanese residents living in Japan undergoing COVID-19 situation: A cross-sectional survey

Author

Luu, Mai Ngoc, primary, Imoto, Atsuko, additional, Matsuo, Yoshimi, additional, Huy, Nguyen Tien, additional, Qarawi, Ahmad, additional, Alhady, Shamael Thabit Mohammed, additional, Truong, Le Van, additional, Yoshino, Ryuji, additional, Duc, Nguyen Tran Minh, additional, Tabei, Kozue, additional, Lu, Yixiao, additional, Singh, Manmeet Kaur, additional, Truong, Mai Phuong, additional, Dumre, Shyam Prakash, additional, Rocha, Ian Christopher Naungayan, additional, Hung, I-Chun, additional, Fudo, Akane, additional, Sato, Miho, additional, Kansakar, Sajog, additional, Tsukamoto, Akiko, additional, Komatsu, Aiko, additional, Cai, Guoxi, additional, Moji, Kazuhiko, additional, Khongyot, Thanawat, additional, Mogan, Saruveish, additional, Soukdavone, Souksavath, additional, Hartuti, Endah Dwi, additional, Thidatheb, Kounnavong, additional, Honda, Shiho, additional, Woo, Hyunjae, additional, Lama, Nitu, additional, Huynh, Vy Thi Nhat, additional, Khoa, Huynh Le Anh, additional, Abbas, Kirellos Said, additional, Monib, Fatma A., additional, Omran, Hoda Aly Mohamed, additional, Rezq, Chiristine Samuel, additional, Qatora, Mostafa Shehata, additional, Jia Ng, Sze, additional, Morena, Graca Jaqueline Vanessa, additional, Miranda, Adriana Viola, additional, Ngo Huynh, Minh-Trang, additional, Ota, Junko, additional, Minjung, Kim, additional, An, Jaemin, additional, Vorlasane, Latdavanh, additional, Gunasegaran, Kesshinee, additional, Zulkefli, Fazureen, additional, Lima Girón, Belen de Jesús, additional, Bhattachan, Punita Gauchan, additional, Dumre, Renu Bhandari, additional, Pandey, Kishor, additional, Yamashita, Sarina, additional, Seposo, Aden Kay Celis, additional, Zabala, Jayson, additional, Riva-Moscoso, Adrián, additional, Ordóñez, Joyce Nicole Pineda, additional, Uitrakul, Suriyon, additional, Principe-Meneses, Fortunato S., additional, and Dila, Kadek Agus Surya, additional

Published
2024
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4. COVID-19 vaccination intention and vaccine characteristics influencing vaccination acceptance: a global survey of 17 countries

Author

Wong, Li Ping, Alias, Haridah, Danaee, Mahmoud, Ahmed, Jamil, Lachyan, Abhishek, Cai, Carla Zi, Lin, Yulan, Hu, Zhijian, Tan, Si Ying, Lu, Yixiao, Cai, Guoxi, Nguyen, Di Khanh, Seheli, Farhana Nishat, Alhammadi, Fatma, Madhale, Milkar D., Atapattu, Muditha, Quazi-Bodhanya, Tasmi, Mohajer, Samira, Zimet, Gregory D., and Zhao, Qinjian

Published
2021
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5. Spatial-temporal analysis of tuberculosis infections in a rural prefecture in Japan

Author

Lu, Yixiao, Cai, Guoxi, Arima, Kazuhiko, He, Fei, Zheng, Zejun, Qin, Liang, and Aoyagi, Kiyoshi

Subjects
spatial analysis, Japan, Tuberculosis, space-time cluster, Nagasaki
Abstract

Background: Japan has remained medium-burden tuberculosis (TB) country for many years. However, a considerable variation was observed in the TB space-time distribution among Japan’s eight regions. This study aimed to investigate the spatial, temporal, and space-time dynamics of TB at the machi-level in Nagasaki prefecture. Methods: Data on the reported TB infections from 2007 to 2018 were collected from the information center for infectious diseases of the Nagasaki Prefectural Institute of Environment and Public Health. The time series, temporal trends, and spatial patterns of TB at the machi-level were explored using Moran’s I and Kulldorff’s space-time scan statistics. Results: A total of 4,364 TB infections were reported between April 2007 and December 2018 in Nagasaki prefecture. The infections were frequently reported in October, June, and January, and they showed spatial clustering with Moran’s I value ranging from 0.07 to 0.17 (p = 0.001). Ten significant clusters were identified, including one most likely cluster and nine secondary clusters, which were mainly concentrated in the densely inhabited districts of the two biggest cities in Nagasaki prefecture (Nagasaki city and Sasebo city), Shimabara peninsula, and Iki island. Conclusion: This study showed significant and unique spatial-temporal characteristics of TB infections in Nagasaki prefecture. Therefore, such information on the prevailing epidemiological situation of TB infections could help develop strategies that could effectively eliminate TB in Japan., Acta medica Nagasakiensia, 66(2), pp.41-49; 2023

Published
2023

6. Acceptance and Preference for COVID-19 Vaccine among Japanese Residents at Early Stage of the Epidemic in Japan

Author

Wu, Jiwen, Cai, Guoxi, Fan, Yi, Arima, Kazuhiko, Lin, Yulan, Wong, Liping, Zhang, Zhuo, Yamamoto, Taro, Morita, Kouichi, Yoshikawa, Akira, Lu, Yixiao, Aoyagi, Kiyoshi, Wu, Jiwen, Cai, Guoxi, Fan, Yi, Arima, Kazuhiko, Lin, Yulan, Wong, Liping, Zhang, Zhuo, Yamamoto, Taro, Morita, Kouichi, Yoshikawa, Akira, Lu, Yixiao, and Aoyagi, Kiyoshi

Abstract

Background: This study aimed to survey the attitudes toward COVID-19 vaccines and their acceptability among the Japanese public as soon as the United States Food and Drug Administration (FDA) authorized vaccines and their rollouts started around the world. Methods: An anonymous cross-sectional survey was conducted in Japan between 4 January and 5 March 2021. A questionnaire was administered to evaluate attitudes toward COVID-19 vaccines according to demographic characteristics, vaccine characteristics, and vaccine production. Results: A total of 1037 completed responses were received. More than half (63.5%) of the participants responded positively (extremely likely/likely) toward COVID-19 vaccines. The highest acceptance to be vaccinated was discovered among the youngest age group. As expected, participants who had never delayed acceptance or refused the vaccine in their history of vaccination had a significantly higher willingness to be vaccinated against COVID-19 (p < 0.001). Females (OR = 2.66, 95% CI: 1.99–3.58) and participants who had ever delayed acceptance or refuse the vaccine (OR = 3.49, 95% CI: 2.42–5.05) had higher odds of COVID-19 vaccine hesitancy. Participants with a postgraduate degree (OR = 0.64, 95% CI: 0.40–1.00) presented the highest willingness to be vaccinated against COVID-19. More than two-thirds (72.9%, 95% CI: 70.4%–75.8%) of the participants did not mind a booster dose required following primary vaccination. A total of 63.2% (95% CI: 60.0%–66.0%) of the participants only accepted a nearly 90% effective or above vaccine at preventing COVID-19. At the same, 86.4% (95% CI: 84.4%–88.4%) of the participants reported only accepting a vaccine with minor side effects. Conclusions: The moderate levels of COVID-19 vaccine acceptance found in the early phase of the pandemic demonstrate that it is important to improve the implementation of effective management for vaccine promotion and the acceptability of the vaccine to slow or delay transmission., Vaccines, 11(1), art. no. 157; 2023

Published
2023

10. Figures and Tables;Supporting information from Facile preparation of Fe3O4@Pt nanoparticles as peroxidase mimics for sensitive glucose detection by a paper-based colorimetric assay;Data for figures from Facile preparation of Fe3O4@Pt nanoparticles as peroxidase mimics for sensitive glucose detection by a paper-based colorimetric assay

Author

He, Ye, Wang, Panlin, Chen, Xiaojing, Li, Yahuang, Wei, Jiajun, Cai, Guoxi, Aoyagi, Kiyoshi, and Wang, Wenxiang

Abstract

Fig.S1 Low(A) - and (B) high-magnification TEM images of Fe3O4 NPs. (C) EDS spectrums of Fe3O4 NPs. (D) Size distribution of Fe3O4 NPs. Fig. S2 Steady-state kinetic assays and the corresponding double reciprocal (Lineweaver-Burk) plots of Fe3O4@Pt NPs for (A, B) H2O2 and (C, D) TMB. Fig. S3 (A) the UV-vis spectrum of the H2O2 concentration change and (B) Dose-response curve of H2O2 concentration and absorbance (the inset shows the corresponding homology calibration curve and colorimetric photographs). Table S1 Apparent kinetic parameters of Fe3O4@Pt NPs as both peroxidase mimetics. Table S2 Performance comparison of various materials for detecting H2O2. Table S3 Performance comparison of various nanomaterials for Glucose detection.

Published
2022
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11. Figures and Tables;Supporting information from Facile preparation of Fe3O4@Pt nanoparticles as peroxidase mimics for sensitive glucose detection by a paper-based colorimetric assay;Data for figures

Author

He, Ye, Wang, Panlin, Chen, Xiaojing, Li, Yahuang, Wei, Jiajun, Cai, Guoxi, Aoyagi, Kiyoshi, and Wang, Wenxiang

Abstract

Fig.S1 Low(A) - and (B) high-magnification TEM images of Fe3O4 NPs. (C) EDS spectrums of Fe3O4 NPs. (D) Size distribution of Fe3O4 NPs. Fig. S2 Steady-state kinetic assays and the corresponding double reciprocal (Lineweaver-Burk) plots of Fe3O4@Pt NPs for (A, B) H2O2 and (C, D) TMB. Fig. S3 (A) the UV-vis spectrum of the H2O2 concentration change and (B) Dose-response curve of H2O2 concentration and absorbance (the inset shows the corresponding homology calibration curve and colorimetric photographs). Table S1 Apparent kinetic parameters of Fe3O4@Pt NPs as both peroxidase mimetics. Table S2 Performance comparison of various materials for detecting H2O2. Table S3 Performance comparison of various nanomaterials for Glucose detection.

Published
2022
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12. Additional file 1 of COVID-19 vaccination intention and vaccine characteristics influencing vaccination acceptance: a global survey of 17 countries

Author

Wong, Li Ping, Alias, Haridah, Danaee, Mahmoud, Ahmed, Jamil, Lachyan, Abhishek, Cai, Carla Zi, Lin, Yulan, Hu, Zhijian, Tan, Si Ying, Lu, Yixiao, Cai, Guoxi, Nguyen, Di Khanh, Seheli, Farhana Nishat, Alhammadi, Fatma, Madhale, Milkar D., Atapattu, Muditha, Quazi-Bodhanya, Tasmi, Mohajer, Samira, Zimet, Gregory D., and Zhao, Qinjian

Abstract

Additional file 1. Questionnaire.

Published
2021
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13. Additional file 4 of COVID-19 vaccination intention and vaccine characteristics influencing vaccination acceptance: a global survey of 17 countries

Author

Wong, Li Ping, Alias, Haridah, Danaee, Mahmoud, Ahmed, Jamil, Lachyan, Abhishek, Cai, Carla Zi, Lin, Yulan, Hu, Zhijian, Tan, Si Ying, Lu, Yixiao, Cai, Guoxi, Nguyen, Di Khanh, Seheli, Farhana Nishat, Alhammadi, Fatma, Madhale, Milkar D., Atapattu, Muditha, Quazi-Bodhanya, Tasmi, Mohajer, Samira, Zimet, Gregory D., and Zhao, Qinjian

Abstract

Additional file 4. Participant demographics, vaccine characteristics influencing vaccination acceptance and vaccine characteristics influencing choice by country.

Published
2021
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14. Additional file 6 of COVID-19 vaccination intention and vaccine characteristics influencing vaccination acceptance: a global survey of 17 countries

Author

Wong, Li Ping, Alias, Haridah, Danaee, Mahmoud, Ahmed, Jamil, Lachyan, Abhishek, Cai, Carla Zi, Lin, Yulan, Hu, Zhijian, Tan, Si Ying, Lu, Yixiao, Cai, Guoxi, Nguyen, Di Khanh, Seheli, Farhana Nishat, Alhammadi, Fatma, Madhale, Milkar D., Atapattu, Muditha, Quazi-Bodhanya, Tasmi, Mohajer, Samira, Zimet, Gregory D., and Zhao, Qinjian

Abstract

Additional file 6. Factors influencing COVID-19 vaccine hesitancy by country.

Published
2021
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15. Additional file 3 of COVID-19 vaccination intention and vaccine characteristics influencing vaccination acceptance: a global survey of 17 countries

Author

Wong, Li Ping, Alias, Haridah, Danaee, Mahmoud, Ahmed, Jamil, Lachyan, Abhishek, Cai, Carla Zi, Lin, Yulan, Hu, Zhijian, Tan, Si Ying, Lu, Yixiao, Cai, Guoxi, Nguyen, Di Khanh, Seheli, Farhana Nishat, Alhammadi, Fatma, Madhale, Milkar D., Atapattu, Muditha, Quazi-Bodhanya, Tasmi, Mohajer, Samira, Zimet, Gregory D., and Zhao, Qinjian

Abstract

Additional file 3. Participant demographics, vaccine characteristics influencing vaccination acceptance and vaccine characteristics influencing choice by region.

Published
2021
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16. Additional file 7 of COVID-19 vaccination intention and vaccine characteristics influencing vaccination acceptance: a global survey of 17 countries

Author

Wong, Li Ping, Alias, Haridah, Danaee, Mahmoud, Ahmed, Jamil, Lachyan, Abhishek, Cai, Carla Zi, Lin, Yulan, Hu, Zhijian, Tan, Si Ying, Lu, Yixiao, Cai, Guoxi, Nguyen, Di Khanh, Seheli, Farhana Nishat, Alhammadi, Fatma, Madhale, Milkar D., Atapattu, Muditha, Quazi-Bodhanya, Tasmi, Mohajer, Samira, Zimet, Gregory D., and Zhao, Qinjian

Abstract

Additional file 7. Vaccine characteristics influencing vaccination acceptance by demographics for individual country.

Published
2021
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17. Additional file 2 of COVID-19 vaccination intention and vaccine characteristics influencing vaccination acceptance: a global survey of 17 countries

Author

Wong, Li Ping, Alias, Haridah, Danaee, Mahmoud, Ahmed, Jamil, Lachyan, Abhishek, Cai, Carla Zi, Lin, Yulan, Hu, Zhijian, Tan, Si Ying, Lu, Yixiao, Cai, Guoxi, Nguyen, Di Khanh, Seheli, Farhana Nishat, Alhammadi, Fatma, Madhale, Milkar D., Atapattu, Muditha, Quazi-Bodhanya, Tasmi, Mohajer, Samira, Zimet, Gregory D., and Zhao, Qinjian

Abstract

Additional file 2. The population size of age 15 years and the sample population by country.

Published
2021
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19. The role of education in the association between self-rated health and levels of C-reactive protein : a cross-sectional study in rural areas of China

Author

Tu, Raoping, Pan, Kuan-Yu, Cai, Guoxi, Yamamoto, Taro, Wang, Hui-Xin, Tu, Raoping, Pan, Kuan-Yu, Cai, Guoxi, Yamamoto, Taro, and Wang, Hui-Xin

Abstract

Objectives This study aims to examine the association between self-rated health (SRH) and levels of C-reactive protein (CRP) among adults aged 45 to 101 years old in rural areas of China, and to explore the role of education in the association. Design Cross-sectional study. Setting The study population was derived from two databases in China: Nanping project (NP) and the China Health and Retirement Longitudinal Study (CHARLS). Participants There were 646 participants from a rural area of Nanping (NP) and 8555 rural participants from a national representative sample of China (CHARLS). Methods CRP was measured using a high sensitivity sandwich enzyme immunoassay in the NP and immunoturbidimetric assay in the GNARLS. SRH was assessed by SRH questionnaires and categorised into good and poor. Education was measured by the maximum years of schooling and dichotomised into illiterate and literate. Multivariate linear regression models were used to study the associations. Results Compared to people with good SRH, those with poor SRH had higher levels of CRP in NP beta=0.16, 95% CI -0.02 to 0.34) and in CHARLS (beta=0.07, 95% CI 0.02 to 0.11) after adjusting for potential confounders. Similar findings were observed in the pooled population (beta=0.08, 95% CI 0.03 to 0.12), especially in men (beta=0.13, 95% CI 0.06 to 0.20) and in literate people (beta=0.12, 95% CI 0.06 to 0.18). Conclusion Poor SRH may be a predicator of elevated levels of CRP among middle-aged and older people in rural areas, especially in men and literate people.

Published
2019
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20. Nomograms and risk scores for predicting the risk of oral cancer in different sexes: a large-scale case-control study

Author

Chen, Fa, primary, Lin, Lisong, additional, Yan, Lingjun, additional, Liu, Fengqiong, additional, Qiu, Yu, additional, Wang, Jing, additional, Hu, Zhijian, additional, Wu, Junfeng, additional, Bao, Xiaodan, additional, Lin, Liangkun, additional, Wang, Rui, additional, Cai, Guoxi, additional, Aoyagi, Kiyoshi, additional, Cai, Lin, additional, and He, Baochang, additional

Published
2018
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23. Steps towards Preventive HIV Treatment in Fujian, China: Problems Identified via an Assessment of Initial Antiretroviral Therapy Provision

Author

Xia, Pincang, primary, Okumura, Junko, additional, Yan, Pingping, additional, Xie, Meirong, additional, Wu, Shouli, additional, Zhuang, Meizhu, additional, Zheng, Jian, additional, Zhang, Chunyang, additional, Zhang, Mingya, additional, Kato, Masaya, additional, Cai, GuoXi, additional, and Yamamoto, Taro, additional

Published
2013
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25. Polysaccharides from Enteromorpha prolifera Improve Glucose Metabolism in Diabetic Rats.

Author

Lin, Wenting, Wang, Wenxiang, Liao, Dongdong, Chen, Damiao, Zhu, Pingping, Cai, Guoxi, and Kiyoshi, Aoyagi

Subjects
GLUCOSE metabolism, ENTEROMORPHA, TREATMENT of diabetes, POLYSACCHARIDES, DRUG dosage, LABORATORY rats, THERAPEUTICS
Abstract

This study investigated the effects of polysaccharides from Enteromorpha prolifera (PEP) on glucose metabolism in a rat model of diabetes mellitus (DM). PEP (0, 150, 300, and 600 mg/kg) was administered intragastrically to rats for four weeks. After treatment, fasting blood glucose (FBG) and insulin (INS) levels were measured, and the insulin sensitivity index (ISI) was calculated. The morphopathological changes in the pancreas were observed. Serum samples were collected to measure the oxidant-antioxidant status. The mRNA expression levels of glucokinase (GCK) and insulin receptor (InsR) in liver tissue and glucose transporter type 4 (GLUT-4) and adiponectin (APN) in adipose tissue were determined. Compared with the model group, the FBG and INS levels were lower, the ISI was higher, and the number of islet β-cells was significantly increased in all the PEP groups. In the medium- and high-dose PEP groups, MDA levels decreased, and the enzymatic activities of SOD and GSH-Px increased. The mRNA expression of InsR and GCK increased in all the PEP groups; APN mRNA expression increased in the high-dose PEP group, and GLUT-4 mRNA expression increased in adipose tissue. These findings suggest that PEP is a potential therapeutic agent that can be utilized to treat DM. [ABSTRACT FROM AUTHOR]

Published
2015
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26. Impact of COVID-19 vaccination status on hospitalization and disease severity: A descriptive study in Nagasaki Prefecture, Japan.

Author

Cai G, Liu S, Lu Y, Takaki Y, Matsumoto F, Yoshikawa A, Taguri T, Xie J, Arima K, Mizukami S, Wu J, Yamamoto T, Hasegawa M, Tien Huy N, Saito M, Takeuchi S, Morita K, Aoyagi K, and He F

Subjects
Aged, Humans, Male, Japan epidemiology, COVID-19 Vaccines, Patient Acuity, Hospitalization, Vaccination, COVID-19 epidemiology, COVID-19 prevention & control
Abstract

Coronavirus disease 2019 (COVID-19) was extraordinarily harmful, with high rates of infection and hospitalization. This study aimed to evaluate the impact of COVID-19 vaccination status and other factors on hospitalization and disease severity, using data from Nagasaki Prefecture, Japan. Confirmed cases of COVID-19 infection with vaccination status were included and the differences in characteristics between different vaccination statuses, hospitalization or not, and patients with varying levels of disease severity were analyzed. Furthermore, logistic regression was used to calculate odds ratio (ORs) and 95% confidence intervals (CI) to evaluate the association of various factors with hospitalization and disease severity. From March 14, 2020 to August 31, 2022, 23,139 patients were unvaccinated 13,668 vaccinated the primary program with one or two doses, and 4,575 completed the booster. Vaccination reduced the risk of hospitalization with an odd ratio of 0.759 (95% CI: 0.654-0.881) and the protective effect of completed booster vaccination was more pronounced (OR: 0.261, 95% CI: 0.207-0.328). Similarly, vaccination significantly reduced the risk of disease severity (vaccinated primary program: OR: 0.191, 95% CI: 0.160-0.228; completed booster vaccination: OR: 0.129, 95% CI: 0.099-0.169). Overall, unvaccinated, male, elderly, immunocompromised, obese, and patients with other severe illness factors were all risk factors for COVID-19-related hospitalization and disease severity. Vaccination was associated with a decreased risk of hospitalization and disease severity, and highlighted the benefits of completing booster.

Published
2024
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