185 results on '"Chen, Chiung-Tong"'
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2. A bubble bursting-mediated oral drug delivery system that enables concurrent delivery of lipophilic and hydrophilic chemotherapeutics for treating pancreatic tumors in rats
3. CCM111 prevents hepatic fibrosis via cooperative inhibition of TGF-β, Wnt and STAT3 signaling pathways
4. Comparative study between deep learning and QSAR classifications for TNBC inhibitors and novel GPCR agonist discovery
5. Abstract 523: Targeting myc-amplified cancers with a novel prodrug inhibiting aurora A kinase
6. Correction: Lee et al. The Synergistic Inhibition of Coronavirus Replication and Induced Cytokine Production by Ciclesonide and the Tylophorine-Based Compound Dbq33b. Pharmaceutics 2022, 14, 1511
7. BPR0C261, An Analogous of Microtubule Disrupting Agent D-24851 Enhances the Radiosensitivity of Human Non-Small Cell Lung Cancer Cells via p53-Dependent and p53-Independent Pathways
8. Protective Effect of CXCR4 Antagonist DBPR807 against Ischemia-Reperfusion Injury in a Rat and Porcine Model of Myocardial Infarction: Potential Adjunctive Therapy for Percutaneous Coronary Intervention
9. The Synergistic Inhibition of Coronavirus Replication and Induced Cytokine Production by Ciclesonide and the Tylophorine-Based Compound Dbq33b
10. Synthesis and Evaluation of Small Molecule Drug Conjugates Harnessing Thioester-Linked Maytansinoids
11. Treatment of chemotherapy-induced neutropenia in a rat model by using multiple daily doses of oral administration of G-CSF-containing nanoparticles
12. Combination therapy via oral co-administration of insulin- and exendin-4-loaded nanoparticles to treat type 2 diabetic rats undergoing OGTT
13. Furin and TMPRSS2 Resistant Spike Induces Robust Humoral and Cellular Immunity Against SARS-CoV-2 Lethal Infection
14. Effects of pH on molecular mechanisms of chitosan–integrin interactions and resulting tight-junction disruptions
15. Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules
16. Elucidating the signaling mechanism of an epithelial tight-junction opening induced by chitosan
17. Click Chemistry and Multicomponent Reaction for Linker Diversification of Zinc Dipicolylamine-Based Drug Conjugates
18. Implanted islet mass influences the effects of dipeptidyl peptidase-IV inhibitor LAF237 on transplantation outcomes in diabetic mice
19. Immune response and pathophysiological features of Klebsiella pneumoniae liver abscesses in an animal model
20. Effects of chitosan-nanoparticle-mediated tight junction opening on the oral absorption of endotoxins
21. Remdesivir and Cyclosporine Synergistically Inhibit the Human Coronaviruses OC43 and SARS-CoV-2
22. In vivo evaluation of safety and efficacy of self-assembled nanoparticles for oral insulin delivery
23. R432 is a key residue for the multiple functions of Ndt80p in Candida albicans
24. BPRDP056, a novel small molecule drug conjugate specifically targeting phosphatidylserine for cancer therapy
25. Inhibition of SARS-CoV-2 by Highly Potent Broad-Spectrum Anti-Coronaviral Tylophorine-Based Derivatives
26. Effects of paclitaxel and doxorubicin in histocultures of hepatocelular carcinomas
27. Paclitaxel-loaded poly( γ-glutamic acid)-poly(lactide) nanoparticles as a targeted drug delivery system for the treatment of liver cancer
28. BPR0C261 is a novel orally active antitumor agent with antimitotic and anti-angiogenic activities
29. Discovery of M Protease Inhibitors Encoded by SARS-CoV-2
30. Abstract 1937: BPR6K609: An Aurora kinase inhibitor targeting small cell lung cancer with MYC amplification
31. Repurposing old drugs as antiviral agents for coronaviruses
32. Artificial intelligence approach fighting COVID-19 with repurposing drugs
33. Impacts of Intralipid on Nanodrug Abraxane Therapy and on the Innate Immune System
34. Effects of boschnaloside from Boschniakia rossica on dysglycemia and islet dysfunction in severely diabetic mice through modulating the action of glucagon-like peptide-1
35. Impaired Phagocytosis of Capsular Serotypes K1 or K2 Klebsiella pneumoniae in Type 2 Diabetes Mellitus Patients with Poor Glycemic Control
36. A Dengue Virus Type 2 (DENV-2) NS4B-Interacting Host Factor, SERP1, Reduces DENV-2 Production by Suppressing Viral RNA Replication
37. Mutagenesis of the dengue virus NS4A protein reveals a novel cytosolic N-terminal domain responsible for virus-induced cytopathic effects and intramolecular interactions within the N-terminus of NS4A
38. Synthesis and biological evaluation of N-glucosyl indole derivatives as sodium-dependent glucose co-transporter 2 inhibitors
39. Citronellol Induces Necroptosis of Human Lung Cancer Cells via TNF-α Pathway and Reactive Oxygen Species Accumulation
40. BPR 1J373, a novel multitargeted kinase inhibitor, effectively suppresses the growth of gastrointestinal stromal tumor
41. Time-and concentration-dependent penetration of doxorubicin in prostate tumors
42. CCM111, the water extract of Antrodia cinnamomea, regulates immune-related activity through STAT3 and NF-κB pathways
43. 1-(2,4-Dibromophenyl)-3,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indazol-4-one
44. A Novel CXCR4 Antagonist CX549 Induces Neuroprotection in Stroke Brain
45. Discovery of BPR1K871, a quinazoline based, multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation
46. BPR1J373, an Oral Multiple Tyrosine Kinase Inhibitor, Targets c-KIT for the Treatment of c-KIT–Driven Myeloid Leukemia
47. BPR1J373, a novel multitargeted kinase inhibitor, effectively suppresses the growth of gastrointestinal stromal tumor.
48. Self-assembling bubble carriers for oral protein delivery
49. Abstract 3527: YYEI motif is critical to oncogenicity of 14-3-3 proteins
50. Abstract 1756: Novel irreversible EGFR tyrosine kinase inhibitor, DBPR112, as a therapeutic candidate for lung adenocarcinoma
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