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Tripropyl phosphate (TnPP) is a commonly used organic phosphate flame retardant in the textiles, plastics, and coating industries. Residues are commonly detected in samples from the environment and food. The availability of certified reference materials (CRMs) is essential to ensure the accuracy and traceability of detection results. In this study, a comprehensive characterization of a CRM for TnPP was carried out, and its purity was evaluated using two distinct methodologies: mass balance (MB) and quantitative nuclear magnetic resonance spectroscopy (qNMR). In the MB method, the levels of structurally related organic impurities are 1.37 mg/g. The water content was determined to be 3.16 mg/g, while inorganic impurities were found to be 0.87 mg/g, and no residual organic solvents were detected. Benzoic acid and monocrotophos were chosen as internal standards for 1H-qNMR and 31P-qNMR, respectively. The purity of the TnPP CRM was assessed as 994.6 mg/g, 994.1 mg/g, and 993.5 mg/g using MB, 1H-qNMR, and 31P-qNMR techniques, respectively. The verified purity of the TnPP CRM was ultimately determined to be 994.1 mg/g, with an expanded uncertainty of 3.4 mg/g (k = 2), ensuring traceability to the International System of Units (SI). This CRM can be effectively utilized for preparing calibration solutions suitable for the routine monitoring of TnPP residues in plastics and food samples. [ABSTRACT FROM AUTHOR]

Luminescent Ln-MOFs (Eu0.075Tb0.925-MOF) were successfully synthesised through the solvothermal reaction of Tb(NO3)3·6H2O, Eu(NO3)3·6H2O, and the ligand pyromellitic acid. The product was characterised by X-ray diffraction (XRD), TG analysis, EM, X-ray photoelectron spectroscopy (XPS), and luminescence properties, and results show that the synthesised material Eu0.075Tb0.925-MOF has a selective ratio-based fluorescence response to Fe3+ or Cr2O72−. On the basis of the internal filtering effect, the fluorescence detection experiment shows that as the concentration of Fe3+ or Cr2O72− increases, the intensity of the characteristic emission peak at 544 nm of Tb3+ decreases, and the intensity of the characteristic emission peak at 653 nm of Eu3+ increases in Eu0.075Tb0.925-MOF. The fluorescence intensity ratio (I653/I544) has a good linear relationship with the target concentration. The detection linear range for Fe3+ or Cr2O72− is 10–100 μM/L, and the detection limits are 2.71 × 10−7 and 8.72 × 10−7 M, respectively. Compared with the sensor material with a single fluorescence emission, the synthesised material has a higher anti-interference ability. The synthesised Eu0.075Tb0.925-MOF can be used as a highly selective and recyclable sensing material for Fe3+ or Cr2O72−. This material should be an excellent candidate for multifunctional sensors. [ABSTRACT FROM AUTHOR]

The excellent stability of covalent organic frameworks (COFs) and the diversity of metal organic frameworks (MOFs) make MOF/COF hybrid materials promising candidates for chromatographic stationary phases. In this paper, a TpBD/UiO-66-NH 2 hybrid material was synthesized through a Schiff-base reaction between TpBD COFs and UiO-66-NH 2 MOFs; characterized using Fourier-transform infrared spectroscopy, X-ray diffraction, and X-ray photoelectron spectroscopy; and bonded to a capillary to prepare a TpBD/UiO-66-NH 2 -bonded open tubular capillary electrochromatography (OT-CEC) column. Results suggested that the hybrid material had the crystal morphology of a single COF and MOF, a micro-mesoporous structure, and good thermal stability. The inner surface of the OT-CEC column was tightly and uniformly distributed with the stationary phase (∼1.5 μm). The baseline separation of 13 amino acids and three families (4 acidic antibiotics, 4 preservatives and 6 sulfonamides) of emerging pollutant mixtures was achieved due to the synergistic effect of TpBD and UiO-66-NH 2 in the stationary phase. The OT-CEC column showed good reproducibility and stability with relative standard deviations of migration time and resolutions in the range of 1.17-3.93% and 1.79-4.31%, respectively., Competing Interests: The authors declare no competing interests., (This journal is © The Royal Society of Chemistry.)

Hg 2+ is one of the most toxic chemical species in the water environment, and thus developing a new fluorescent covalent organic framework for both the detection and removal of Hg 2+ is highly desirable. Herein, a fluorescent composite, termed TpPa-1 COF@CDs, was synthesized by inverse emulsion polymerization method using an imine covalent organic framework as the supporting material and carbon dots as the fluorescent sensor element. The crystallinity, porosity, rich functional receptors (hydroxyl and amino groups), thermal stability and fluorescent properties of TpPa-1 COF@CDs were characterized. The results showed that TpPa-1 COF@CDs exhibited a good detection and removal performance for Hg 2+ , which was evidenced by its high sensitivity (LOD = 0.75 μg L -1 ), superior selectivity, large adsorption capacity (235 mg g -1 ), fast adsorption rate (30 min equilibrium time) and good regeneration (at least five cycles). More importantly, the simple functional monomer, short reaction time and metal-free raw material made TpPa-1 COF@CDs reliable, cost effective and eco-friendly. This research demonstrated the facile construction of a functional covalent organic framework composite for water environmental remediation technologies of metal pollution., Competing Interests: There are no conflicts to declare., (This journal is © The Royal Society of Chemistry.)

Quantum dots (QDs) and carbon quantum dots (CDs) are classes of zero-dimensional materials whose sizes can be ≤10 nm. They exhibit excellent optical properties and are widely used to prepare fluorescent probes for qualitative and quantitative detection of test objects. In this article, we used cerium chloride as the cerium source and used the in situ doped cerium (rare-earth element) to develop cadmium telluride (CdTe) quantum dots following the aqueous phase method. CdTe: Ce quantum dots were successfully synthesized. The solution of CdTe:Ce QDs was mixed with the CD solution prepared following the green microwave method to form a ratio fluorescence sensor that can be potentially used for the selective detection of mercury ions (Hg 2+ ). We used transmission electron microscopy, X-ray photoelectron spectroscopy, X-ray diffraction, and other microscopy and spectral characterization techniques to validate that Ce had been successfully doped. The test results on the fluorescence performance revealed that Ce doping enhances the predoped fluorescence performance of the CdTe QDs. We have quantitatively detected Hg 2+ using a ratiometric fluorescence sensor to show that in the range of 10-60 nM, the fluorescence quenching efficiency increases linearly with the increase in Hg 2+ concentration. The linear correlation coefficient R 2 = 0.9978, and its detection limit was found to be 2.63 nM L -1 . It was observed that other interfering ions do not significantly affect the fluorescence intensity of the probe. According to the results of the blank addition experiment, the developed proportional fluorescence probe can be used for the detection of Hg 2+ in actual samples., Competing Interests: The authors declare no competing financial interest., (© 2021 The Authors. Published by American Chemical Society.)

Quantum dots (QDs) are a class of zero-dimensional nanocrystal materials, whose lengths are limited to 2-10 nm. Their unique advantages such as wide excitation spectra, narrow emission spectra, and high quantum yield make their application possible in fluorescence sensing, wherein QDs such as CdSe, CdTe, and CdS are used. Indeed, QDs have a wide range of applications in fluorescence sensing, and there have been many reports of applications based on QDs as ion probes. The emission spectra of QDs can be adjusted by changing the size of the QDs or doping them with other ions/elements. However, the high toxicity of Cd and the poor anti-interference ability of single-emission fluorescent probes greatly limit the applications of QDs in many fields. In this paper, ZnS QDs are doped with the rare-earth element Ce to form a low-toxicity double-emission ratiometric fluorescent sensor, ZnS:Ce, for Hg 2+ detection. The results of transmission electron microscopy (TEM), X-ray diffractometry, X-ray photoelectron spectroscopy, and optical spectroscopy show that ZnS:Ce QDs were successfully synthesized. Under the optimal conditions, the concentration of Hg 2+ was in the range of 10-100 μM, which had a linear relationship with the fluorescence intensity of the ZnS:Ce QDs: the linear correlation coefficient was 0.998, and the detection limit was 0.82 μM L -1 . In addition, the fluorescent sensor had good selectivity for Hg 2+ , and it was successfully applied to the detection of Hg 2+ in laboratory water samples., Competing Interests: The authors declare no competing financial interest., (Copyright © 2020 American Chemical Society.)

Background: Whether prasugrel can take the place of clopidogrel for patients with acute coronary syndrome (ACS) is not clear. The aim of this study was to perform a meta-analysis for systematically reviewing the evidence on prasugrel in comparison to clopidogrel in patients with ACS., Material/methods: Relevant prospective and retrospective studies were searched in databases. Six studies were finally included. Pooled risk ratios (RRs) and 95% confidence intervals (CIs) were calculated to assess all causes of death, myocardial infarction (MI), stroke, major bleeding, major/minor bleeding, and stent thrombosis (for PCI performed)., Results: Compared with clopidogrel, prasugrel had similar risks of all cause of death (Pooled RR: 0.83; 95% CI: 0.64-1.06, p=0.14, I2=55%), MI (Pooled RR: 0.86; 95% CI: 0.71-1.04, p=0.12) and stroke (pooled RR: 0.88; 95% CI: 0.70-1.10, p=0.25). However, prasugrel was associated with significantly higher risk of both major bleeding (Pooled RR: 1.19; 95% CI: 0.99-1.44, p=0.06, I2=0%) and the risk of total major and minor bleeding (Pooled RR: 1.30; 95% CI: 1.15-1.48, p<0.0001, I2=0%). For the patients who underwent percutaneous coronary intervention (PCI), prasugrel was associated with significantly lower risk of stent thrombosis (Pooled RR: 0.47; 95% CI: 0.34-0.61, p<0.00001, I2=0%)., Conclusions: Prasugrel has similar effects as clopidogrel in terms of all causes of death, MI, and stroke in ACS patients. For the patients who underwent PCI, prasugrel contributes to lower risk of stent thrombosis. However, prasugrel is associated with significantly higher risk of bleeding. For the patients with active pathological bleeding or a history of stroke and/or TIA, prasugrel should not be recommended.