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13 results on '"Ciancio, Nicola"'

3. Bronchial cast hiding a lung cancer

Author

Migliore Marcello, Ciancio Nicola, Giuliano Riccardo, and Di Maria Giuseppe

Subjects
Airway obstruction, Bronchial cast, Broncoscopy, Haemoptysis, Lung cancer, NSCLC, Diseases of the respiratory system, RC705-779
Abstract

Abstract A 70-year-old man was admitted for severe hypoxia, haemoptysis and cough. Chest-X-ray and CT-scan indicated a right-lower-lobe collapse. Bronchoscopy showed its occlusion by whitish dense mucus. Aspiration revealed a Bronchial Cast (BC) and a stenotic and inflamed orifice of the right-lower-lobe-bronchus which was biopsied. Histopathologic examination of BC showed fibrin with lymphocytes and neutrophils, and, surprisingly, also the presence of lung cancer. Although the association between BC and benign, myxoid-soft-tissue, tracheobronchial tumors has been described, the association with lung cancer has not previously been reported, and it remains unclear whether it is causal or casual.

Published
2012
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4. Prognostic value of p53 and Ki67 expression in fiberoptic bronchial biopsies of patients with non small cell lung cancer

Author

Ciancio Nicola, Galasso Maria Grazia, Campisi Raffaele, Bivona Laura, Migliore Marcello, and Di Maria Giuseppe U

Subjects
Diseases of the respiratory system, RC705-779
Abstract

Abstract Background Overexpression of the tumor suppressor gene p53 and the marker for cellular proliferation Ki67 in open lung biopsies are indicated as predictor factors of survival of patients with lung cancer. However, the prognostic value of p53 and Ki67 in fiberoptic bronchial biopsies (FBB) has not been fully investigated. We evaluated p53 and Ki67 immunostaining in FBB from 19 with Non Small-Cell Lung Cancer (NSCLC: 12 adenocarcinomas, 5 squamous cell carcinomas and 2 NSCLC-NOS). Methods FBB specimens were fixed in formalin, embedded in paraffin, and immunostained using anti-p53 and anti-Ki67 antibodies. Slides were reviewed by two independent observers and classified as positive (+ve) when the number of cells with stained nuclei exceeded 15% for p53 or when >25% positive cells were observed throughout each section for Ki67. Results Positive (+ve) immunostaining was found in 9 patients for p53 (47.37%) and 8 patients for Ki67 (42.10%). We examined overall survival curves of the patients with Mantel's logrank test, both p53 -ve and Ki67 -ve patients had significantly higher survival rates than p53 + ve (p Conclusion This study suggests that negative immunostaining of fiberoptic bronchial biopsies for p53 and Ki67 could represent a better prognostic factor for patients with NSCLC.

Published
2012
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6. Most Italians attending a congress on health of elderly people do not know and do not recognize respiratory diseases

Author

Ciancio, Nicola, primary, Sanguinetti, Claudio M., additional, Falcone, Franco, additional, Taranto, Claudio, additional, Fasani, Roberto, additional, De Benedetto, Fernando, additional, Resta, Onofrio, additional, De Michele, Fausto, additional, Messina, Roberto, additional, Rossi, Andrea, additional, Nardini, Stefano, additional, and Di Maria, Giuseppe, additional

Published
2016
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7. Pleurectomy/decortication and hyperthermic intrapleural chemotherapy for malignant pleural mesothelioma: initial experience

Author

Migliore, Marcello, primary, Calvo, Damiano, additional, Criscione, Alessandra, additional, Palmucci, Stefano, additional, Fuccio Sanzà, Giovanni, additional, Caltabiano, Rosario, additional, Spatola, Corrado, additional, Privitera, Giuseppe, additional, Aiello, Marco Maria, additional, Parra, Hector Soto, additional, Ciancio, Nicola, additional, and Di Maria, Giuseppe, additional

Published
2015
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9. Cytoreductive surgery and hyperthermic intrapleural chemotherapy for malignant pleural diseases: preliminary experience

Author

Migliore, Marcello, primary, Calvo, Damiano, additional, Criscione, Alessandra, additional, Viola, Cristina, additional, Privitera, Giuseppe, additional, Spatola, Corrado, additional, Parra, Hector Soto, additional, Palmucci, Stefano, additional, Ciancio, Nicola, additional, Caltabiano, Rosario, additional, and Maria, Giuseppe Di, additional

Published
2015
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13. Quality standards for the management of bronchiectasis in Italy: A national audit

Author

Maria Pia Foschino Barbaro, Stefano Aliberti, Valentina Conti, Francesco De Blasio, Mauro Carone, Antonio Foresi, Marina Saetta, Marialma Berlendis, Giuseppe Girbino, Pierachille Santus, Michele Vitacca, Salvatore Lo Cicero, Donato Lacedonia, Stefano Centanni, Nicola Ciancio, Vittoria Comellini, Daniela Bonardi, Fulvio Braido, G. F. Schiraldi, Francesca Becciu, Angelo Corsico, Nunzio Crimi, Giuseppe Francesco Sferrazza Papa, Adam T. Hill, Pietro Schino, Piero Ceriana, Alessandro Vatrella, Francesco Menzella, Alessandro Sanduzzi, Carmela Morrone, Pierfranco Usai, Mario Malerba, Caterina Conti, Marco Basile, Sergio Celestino Conte, Marco Mantero, Salvatore Battaglia, Francesco Blasi, Kim Lokar-Oliani, James D. Chalmers, Vincenzo Mastrosimone, Claudia Stochino, Aliberti, S., Hill, A., Mantero, M., Battaglia, S., Centanni, S., Cicero, S., Lacedonia, D., Saetta, M., Chalmers, J., Blasi, F., Morrone, C., Basile, M., Papa, G., Conti, C., Barbaro, M., Lokar-Oliani, K., Schino, P., Vitacca, M., Menzella, F., Sanduzzi, A., Usai, P., Carone, M., Bonardi, D., Crimi, N., Schiraldi, G., Corsico, A., Malerba, M., Becciu, F., Santus, P., Girbino, G., Foresi, A., Comellini, V., Stochino, C., Ceriana, P., Conti, V., Braido, F., Mastrosimone, V., Ciancio, N., Berlendis, M., De Blasio, F., Conte, S., Vatrella, A., Aliberti, Stefano, Hill, Adam T., Mantero, Marco, Battaglia, Salvatore, Centanni, Stefano, Cicero, Salvatore Lo, Lacedonia, Donato, Saetta, Marina, Chalmers, James D., Blasi, Francesco, Morrone, Carmela, Basile, Marco, Papa, Giuseppe Francesco Sferrazza, Conti, Caterina, Barbaro, Maria Pia Foschino, Lokar Oliani, Kim, Schino, Pietro, Vitacca, Michele, Menzella, Francesco, SANDUZZI ZAMPARELLI, Alessandro, Usai, Pierfranco, Carone, Mauro, Bonardi, Daniela Rita, Crimi, Nunzio, Schiraldi, Gianfranco, Corsico, Angelo, Malerba, Mario, Becciu, Francesca, Santus, Pierachille, Girbino, Giuseppe, Foresi, Antonio, Comellini, Vittoria, Stochino, Claudia, Ceriana, Piero, Conti, Valentina, Braido, Fulvio, Mastrosimone, Vincenzo, Ciancio, Nicola, Berlendis, Marialma, De Blasio, Francesco, Conte, Sergio Celestino, and Vatrella, Alessandro

Subjects
Male, Pulmonary and Respiratory Medicine, medicine.medical_specialty, bronchiectasis, media_common.quotation_subject, Symptom Flare Up, Medical audit, Settore MED/10 - Malattie Dell'Apparato Respiratorio, 03 medical and health sciences, 0302 clinical medicine, medicine, Prevalence, Humans, Quality (business), Pseudomonas Infections, 030212 general & internal medicine, Intensive care medicine, National audit, media_common, Aged, Medical Audit, Bronchiectasis, business.industry, Medicine (all), Middle Aged, medicine.disease, Anti-Bacterial Agents, Patient Care Management, 030228 respiratory system, Italy, Needs assessment, Pseudomonas aeruginosa, Female, business, Needs Assessment
Abstract

Although historically considered a neglected disease, bronchiectasis has become a disease of renewed interest over recent decades in light of an increase in prevalence and a substantial burden on healthcare systems. In 2010, the British Thoracic Society (BTS) published guidelines on the management of bronchiectasis in adults, along with specific quality standards. To date, these represent the only quality standards available in Europe. These have been tested over a number of years in the UK with progressive improvements in the standard of care. No national guidelines are available in Italy and no indications on which guideline should be followed have been given by the Italian Society of Respiratory Medicine (SIP). There are limited published data on the quality of bronchiectasis care in Europe outside of the UK. The BTS standards have not been tested in continental Europe or in Italy, where information on characteristics and management of bronchiectasis patients are lacking.

Published
2016

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