180 results on '"Comijs, Hannie"'
Search Results
2. Dysregulation of the hypothalamic pituitary adrenal (HPA) axis and cognitive capability at older ages: individual participant meta-analysis of five cohorts
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Gardner, Michael, Lightman, Stafford, Kuh, Diana, Comijs, Hannie, Deeg, Dorly, Gallacher, John, Geoffroy, Marie-Claude, Kivimaki, Mika, Kumari, Meena, Power, Chris, Hardy, Rebecca, Richards, Marcus, and Ben-Shlomo, Yoav
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- 2019
- Full Text
- View/download PDF
3. Vertraagd lopen en vertraagd denken en gezondheidsrisico’s bij ouderen
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Sanders, Joost, Bremmer, Marijke, Comijs, Hannie, Van de Ven, Peter, Deeg, Dorly, and Beekman, Aartjan
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- 2017
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4. Changes in admission to long-term care institutions in the Netherlands: comparing two cohorts over the period 1996–1999 and 2006–2009
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Alders, Peter, Comijs, Hannie C., and Deeg, Dorly J. H.
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- 2017
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5. De invloed van muziek maken op cognitieve veroudering
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Comijs, Hannie, Mansens, Dieke, and Deeg, Dorly
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- 2017
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6. Huntingtin gene repeat size variations affect risk of lifetime depression
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Gardiner, Sarah L., van Belzen, Martine J., Boogaard, Merel W., van Roon-Mom, Willeke M. C., Rozing, Maarten P., van Hemert, Albert M., Smit, Johannes H., Beekman, Aartjan T. F., van Grootheest, Gerard, Schoevers, Robert A., Oude Voshaar, Richard C., Roos, Raymund A. C., Comijs, Hannie C., Penninx, Brenda W. J. H., van der Mast, Roos C., and Aziz, N. Ahmad
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- 2017
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- View/download PDF
7. Role of vision loss, functional limitations and the supporting network in depression in a general population
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van Nispen, Ruth M. A., Vreeken, Hilde L., Comijs, Hannie C., Deeg, Dorly J. H., and van Rens, Ger H. M. B.
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- 2016
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8. Sleep characteristics across the lifespan in 1.1 million people from the Netherlands, United Kingdom and United States: a systematic review and meta-analysis
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IRAS OH Epidemiology Chemical Agents, dIRAS RA-2, Leerstoel Dekovic, Development and Treatment of Psychosocial Problems, Sub KGP, Urban Accessibility and Social Inclusion, LS IRAS EEPI ME (Milieu epidemiologie), Kocevska, Desana, Lysen, Thom S., Dotinga, Aafje, Koopman-verhoeff, M. Elisabeth, Luijk, Maartje P. C. M., Antypa, Niki, Biermasz, Nienke R., Blokstra, Anneke, Brug, Johannes, Burk, Wiliam J., Comijs, Hannie C., Corpeleijn, Eva, Dashti, Hassan S., De Bruin, Eduard J., De Graaf, Ron, Derks, Ivonne P. M., Dewald-kaufmann, Julia F., Elders, Petra J. M., Gemke, Reinoldus J. B. J., Grievink, Linda, Hale, Lauren, Hartman, Catharina A., Heijnen, Cobi J., Huisman, Martijn, Huss, Anke, Ikram, M. Arfan, Jones, Samuel E., Velderman, Mariska Klein, Koning, Maaike, Meijer, Anne Marie, Meijer, Kim, Noordam, Raymond, Oldehinkel, Albertine J., Groeniger, Joost Oude, Penninx, Brenda W. J. H., Picavet, H. Susan J., Pieters, Sara, Reijneveld, Sijmen A., Reitz, Ellen, Renders, Carry M., Rodenburg, Gerda, Rutters, Femke, Smith, Matt C., Singh, Amika S., Snijder, Marieke B., Stronks, Karien, Ten Have, Margreet, Twisk, Jos W. R., Van De Mheen, Dike, Van Der Ende, Jan, Van Der Heijden, Kristiaan B., Van Der Velden, Peter G., Van Lenthe, Frank J., Van Litsenburg, Raphaële R. L., Van Oostrom, Sandra H., Van Schalkwijk, Frank J., Sheehan, Connor M., Verheij, Robert A., Verhulst, Frank C., Vermeulen, Marije C. M., Vermeulen, Roel C. H., Verschuren, W. M. Monique, Vrijkotte, Tanja G. M., Wijga, Alet H., Willemen, Agnes M., Ter Wolbeek, Maike, Wood, Andrew R., Xerxa, Yllza, Bramer, Wichor M., Franco, Oscar H., Luik, Annemarie I., Van Someren, Eus J. W., Tiemeier, Henning, IRAS OH Epidemiology Chemical Agents, dIRAS RA-2, Leerstoel Dekovic, Development and Treatment of Psychosocial Problems, Sub KGP, Urban Accessibility and Social Inclusion, LS IRAS EEPI ME (Milieu epidemiologie), Kocevska, Desana, Lysen, Thom S., Dotinga, Aafje, Koopman-verhoeff, M. Elisabeth, Luijk, Maartje P. C. M., Antypa, Niki, Biermasz, Nienke R., Blokstra, Anneke, Brug, Johannes, Burk, Wiliam J., Comijs, Hannie C., Corpeleijn, Eva, Dashti, Hassan S., De Bruin, Eduard J., De Graaf, Ron, Derks, Ivonne P. M., Dewald-kaufmann, Julia F., Elders, Petra J. M., Gemke, Reinoldus J. B. J., Grievink, Linda, Hale, Lauren, Hartman, Catharina A., Heijnen, Cobi J., Huisman, Martijn, Huss, Anke, Ikram, M. Arfan, Jones, Samuel E., Velderman, Mariska Klein, Koning, Maaike, Meijer, Anne Marie, Meijer, Kim, Noordam, Raymond, Oldehinkel, Albertine J., Groeniger, Joost Oude, Penninx, Brenda W. J. H., Picavet, H. Susan J., Pieters, Sara, Reijneveld, Sijmen A., Reitz, Ellen, Renders, Carry M., Rodenburg, Gerda, Rutters, Femke, Smith, Matt C., Singh, Amika S., Snijder, Marieke B., Stronks, Karien, Ten Have, Margreet, Twisk, Jos W. R., Van De Mheen, Dike, Van Der Ende, Jan, Van Der Heijden, Kristiaan B., Van Der Velden, Peter G., Van Lenthe, Frank J., Van Litsenburg, Raphaële R. L., Van Oostrom, Sandra H., Van Schalkwijk, Frank J., Sheehan, Connor M., Verheij, Robert A., Verhulst, Frank C., Vermeulen, Marije C. M., Vermeulen, Roel C. H., Verschuren, W. M. Monique, Vrijkotte, Tanja G. M., Wijga, Alet H., Willemen, Agnes M., Ter Wolbeek, Maike, Wood, Andrew R., Xerxa, Yllza, Bramer, Wichor M., Franco, Oscar H., Luik, Annemarie I., Van Someren, Eus J. W., and Tiemeier, Henning
- Published
- 2021
9. Sleep characteristics across the lifespan in 1.1 million people from the Netherlands, United Kingdom and United States: a systematic review and meta-analysis
- Author
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Kocevska, Desana, Lysen, Thom S., Dotinga, Aafje, Koopman-Verhoeff, M. Elisabeth, Luijk, Maartje P.C.M., Antypa, Niki, Biermasz, Nienke R., Blokstra, Anneke, Brug, Johannes, Burk, Wiliam J., Comijs, Hannie C., Corpeleijn, Eva, Dashti, Hassan S., de Bruin, Eduard J., de Graaf, Ron, Derks, Ivonne P.M., Dewald-Kaufmann, Julia F., Elders, Petra J.M., Gemke, Reinoldus J.B.J., Grievink, Linda, Hale, Lauren, Hartman, Catharina A., Heijnen, Cobi J., Huisman, Martijn, Huss, Anke, Ikram, M. Arfan, Jones, Samuel E., Velderman, Mariska Klein, Koning, Maaike, Meijer, Anne Marie, Meijer, Kim, Noordam, Raymond, Oldehinkel, Albertine J., Groeniger, Joost Oude, Penninx, Brenda W.J.H., Picavet, H. Susan J., Pieters, Sara, Reijneveld, Sijmen A., Reitz, Ellen, Renders, Carry M., Rodenburg, Gerda, Rutters, Femke, Smith, Matt C., Singh, Amika S., Snijder, Marieke B., Stronks, Karien, ten Have, Margreet, Twisk, Jos W.R., Van de Mheen, Dike, van der Ende, Jan, van der Heijden, Kristiaan B., van der Velden, Peter G., van Lenthe, Frank J., van Litsenburg, Raphaële R.L., van Oostrom, Sandra H., van Schalkwijk, Frank J., Sheehan, Connor M., Verheij, Robert A., Verhulst, Frank C., Vermeulen, Marije C.M., Vermeulen, Roel C.H., Verschuren, W. M.Monique, Vrijkotte, Tanja G.M., Wijga, Alet H., Willemen, Agnes M., ter Wolbeek, Maike, Wood, Andrew R., Xerxa, Yllza, Bramer, Wichor M., Franco, Oscar H., Luik, Annemarie I., Van Someren, Eus J.W., Tiemeier, Henning, Kocevska, Desana, Lysen, Thom S., Dotinga, Aafje, Koopman-Verhoeff, M. Elisabeth, Luijk, Maartje P.C.M., Antypa, Niki, Biermasz, Nienke R., Blokstra, Anneke, Brug, Johannes, Burk, Wiliam J., Comijs, Hannie C., Corpeleijn, Eva, Dashti, Hassan S., de Bruin, Eduard J., de Graaf, Ron, Derks, Ivonne P.M., Dewald-Kaufmann, Julia F., Elders, Petra J.M., Gemke, Reinoldus J.B.J., Grievink, Linda, Hale, Lauren, Hartman, Catharina A., Heijnen, Cobi J., Huisman, Martijn, Huss, Anke, Ikram, M. Arfan, Jones, Samuel E., Velderman, Mariska Klein, Koning, Maaike, Meijer, Anne Marie, Meijer, Kim, Noordam, Raymond, Oldehinkel, Albertine J., Groeniger, Joost Oude, Penninx, Brenda W.J.H., Picavet, H. Susan J., Pieters, Sara, Reijneveld, Sijmen A., Reitz, Ellen, Renders, Carry M., Rodenburg, Gerda, Rutters, Femke, Smith, Matt C., Singh, Amika S., Snijder, Marieke B., Stronks, Karien, ten Have, Margreet, Twisk, Jos W.R., Van de Mheen, Dike, van der Ende, Jan, van der Heijden, Kristiaan B., van der Velden, Peter G., van Lenthe, Frank J., van Litsenburg, Raphaële R.L., van Oostrom, Sandra H., van Schalkwijk, Frank J., Sheehan, Connor M., Verheij, Robert A., Verhulst, Frank C., Vermeulen, Marije C.M., Vermeulen, Roel C.H., Verschuren, W. M.Monique, Vrijkotte, Tanja G.M., Wijga, Alet H., Willemen, Agnes M., ter Wolbeek, Maike, Wood, Andrew R., Xerxa, Yllza, Bramer, Wichor M., Franco, Oscar H., Luik, Annemarie I., Van Someren, Eus J.W., and Tiemeier, Henning
- Abstract
We aimed to obtain reliable reference charts for sleep duration, estimate the prevalence of sleep complaints across the lifespan and identify risk indicators of poor sleep. Studies were identified through systematic literature search in Embase, Medline and Web of Science (9 August 2019) and through personal contacts. Eligible studies had to be published between 2000 and 2017 with data on sleep assessed with questionnaires including ≥100 participants from the general population. We assembled individual participant data from 200,358 people (aged 1–100 years, 55% female) from 36 studies from the Netherlands, 471,759 people (40–69 years, 55.5% female) from the United Kingdom and 409,617 people (≥18 years, 55.8% female) from the United States. One in four people slept less than age-specific recommendations, but only 5.8% slept outside of the ‘acceptable’ sleep duration. Among teenagers, 51.5% reported total sleep times (TST) of less than the recommended 8–10 h and 18% report daytime sleepiness. In adults (≥18 years), poor sleep quality (13.3%) and insomnia symptoms (9.6–19.4%) were more prevalent than short sleep duration (6.5% with TST <6 h). Insomnia symptoms were most frequent in people spending ≥9 h in bed, whereas poor sleep quality was more frequent in those spending
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- 2021
- Full Text
- View/download PDF
10. Association of Thyroid Dysfunction With Cognitive Function : An Individual Participant Data Analysis
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UCL - SSS/IRSS - Institut de recherche santé et société, van Vliet, Nicolien A., van Heemst, Diana, Almeida, Osvaldo P., Åsvold, Bjørn O., Aubert, Carole E., Bae, Jong Bin, Barnes, Linda E., Bauer, Douglas C., Blauw, Gerard J., Brayne, Carol, Cappola, Anne R., Ceresini, Graziano, Comijs, Hannie C., Dartigues, Jean-Francois, Degryse, Jean-Marie, Dullaart, Robin P. F., van Eersel, Marlise E. A., den Elzen, Wendy P. J., Ferrucci, Luigi, Fink, Howard A., Flicker, Leon, Grabe, Hans J., Han, Ji Won, Helmer, Catherine, Huisman, Martijn, Ikram, M. Arfan, Imaizumi, Misa, de Jongh, Renate T., Jukema, J. Wouter, Kim, Ki Woong, Kuller, Lewis H., Lopez, Oscar L., Mooijaart, Simon P., Moon, Jae Hoon, Moutzouri, Elisavet, Nauck, Matthias, Parle, Jim, Peeters, Robin P., Samuels, Mary H., Schmidt, Carsten O., Schminke, Ulf, Slagboom, P. Eline, Stordal, Eystein, Vaes, Bert, Völzke, Henry, Westendorp, Rudi G. J., Yamada, Michiko, Yeap, Bu B., Rodondi, Nicolas, Gussekloo, Jacobijn, Trompet, Stella, UCL - SSS/IRSS - Institut de recherche santé et société, van Vliet, Nicolien A., van Heemst, Diana, Almeida, Osvaldo P., Åsvold, Bjørn O., Aubert, Carole E., Bae, Jong Bin, Barnes, Linda E., Bauer, Douglas C., Blauw, Gerard J., Brayne, Carol, Cappola, Anne R., Ceresini, Graziano, Comijs, Hannie C., Dartigues, Jean-Francois, Degryse, Jean-Marie, Dullaart, Robin P. F., van Eersel, Marlise E. A., den Elzen, Wendy P. J., Ferrucci, Luigi, Fink, Howard A., Flicker, Leon, Grabe, Hans J., Han, Ji Won, Helmer, Catherine, Huisman, Martijn, Ikram, M. Arfan, Imaizumi, Misa, de Jongh, Renate T., Jukema, J. Wouter, Kim, Ki Woong, Kuller, Lewis H., Lopez, Oscar L., Mooijaart, Simon P., Moon, Jae Hoon, Moutzouri, Elisavet, Nauck, Matthias, Parle, Jim, Peeters, Robin P., Samuels, Mary H., Schmidt, Carsten O., Schminke, Ulf, Slagboom, P. Eline, Stordal, Eystein, Vaes, Bert, Völzke, Henry, Westendorp, Rudi G. J., Yamada, Michiko, Yeap, Bu B., Rodondi, Nicolas, Gussekloo, Jacobijn, and Trompet, Stella
- Abstract
IMPORTANCE In clinical guidelines, overt and subclinical thyroid dysfunction are mentioned as causal and treatable factors for cognitive decline. However, the scientific literature on these associations shows inconsistent findings. OBJECTIVE To assess cross-sectional and longitudinal associations of baseline thyroid dysfunction with cognitive function and dementia. DESIGN, SETTING, AND PARTICIPANTS This multicohort individual participant data analysis assessed 114 267 person-years (median, 1.7-11.3 years) of follow-up for cognitive function and 525 222 person-years (median, 3.8-15.3 years) for dementia between 1989 and 2017. Analyses on cognitive function included 21 cohorts comprising 38 144 participants. Analyses on dementia included eight cohorts with a total of 2033 cases with dementia and 44 573 controls. Data analysis was performed from December 2016 to January 2021. EXPOSURES Thyroid function was classified as overt hyperthyroidism, subclinical hyperthyroidism, euthyroidism, subclinical hypothyroidism, and overt hypothyroidism based on uniform thyrotropin cutoff values and study-specific free thyroxine values. MAIN OUTCOMES AND MEASURES The primary outcomewas global cognitive function, mostly measured using the Mini-Mental State Examination. Executive function, memory, and dementia were secondary outcomes. Analyses were first performed at study level using multivariable linear regression and multivariable Cox regression, respectively. The studies were combined with restricted maximum likelihood meta-analysis. To overcome the use of different scales, results were transformed to standardized mean differences. For incident dementia, hazard ratios were calculated. RESULTS Among 74 565 total participants, 66 567 (89.3%) participants had normal thyroid function, 577 (0.8%) had overt hyperthyroidism, 2557 (3.4%) had subclinical hyperthyroidism, 4167 (5.6%) had subclinical hypothyroidism, and 697 (0.9%) had overt hypothyroidism. The study-specific median age at basel
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- 2021
11. Association of Thyroid Dysfunction With Cognitive Function An Individual Participant Data Analysis
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van Vliet, Nicolien A., van Heemst, Diana, Almeida, Osvaldo P., Asvold, Bjorn O., Aubert, Carole E., Bin Bae, Jong, Barnes, Linda E., Bauer, Douglas C., Blauw, Gerard J., Brayne, Carol, Cappola, Anne R., Ceresini, Graziano, Comijs, Hannie C., Dartigues, Jean-Francois, Degryse, Jean-Marie, Dullaart, Robin P. F., van Eersel, Marlise E. A., den Elzen, Wendy P. J., Ferrucci, Luigi, Fink, Howard A., Flicker, Leon, Grabe, Hans J., Han, Ji Won, Helmer, Catherine, Huisman, Martijn, Ikram, M. Arfan, Imaizumi, Misa, de Jongh, Renate T., Jukema, J. Wouter, Kim, Ki Woong, Kuller, Lewis H., Lopez, Oscar L., Mooijaart, Simon P., Moon, Jae Hoon, Moutzouri, Elisavet, Nauck, Matthias, Parle, Jim, Peeters, Robin P., Samuels, Mary H., Schmidt, Carsten O., Schminke, Ulf, Slagboom, P. Eline, Stordal, Eystein, Vaes, Bert, Volzke, Henry, Westendorp, Rudi G. J., Yamada, Michiko, Yeap, Bu B., Rodondi, Nicolas, Gussekloo, Jacobijn, van Vliet, Nicolien A., van Heemst, Diana, Almeida, Osvaldo P., Asvold, Bjorn O., Aubert, Carole E., Bin Bae, Jong, Barnes, Linda E., Bauer, Douglas C., Blauw, Gerard J., Brayne, Carol, Cappola, Anne R., Ceresini, Graziano, Comijs, Hannie C., Dartigues, Jean-Francois, Degryse, Jean-Marie, Dullaart, Robin P. F., van Eersel, Marlise E. A., den Elzen, Wendy P. J., Ferrucci, Luigi, Fink, Howard A., Flicker, Leon, Grabe, Hans J., Han, Ji Won, Helmer, Catherine, Huisman, Martijn, Ikram, M. Arfan, Imaizumi, Misa, de Jongh, Renate T., Jukema, J. Wouter, Kim, Ki Woong, Kuller, Lewis H., Lopez, Oscar L., Mooijaart, Simon P., Moon, Jae Hoon, Moutzouri, Elisavet, Nauck, Matthias, Parle, Jim, Peeters, Robin P., Samuels, Mary H., Schmidt, Carsten O., Schminke, Ulf, Slagboom, P. Eline, Stordal, Eystein, Vaes, Bert, Volzke, Henry, Westendorp, Rudi G. J., Yamada, Michiko, Yeap, Bu B., Rodondi, Nicolas, and Gussekloo, Jacobijn
- Abstract
IMPORTANCE In clinical guidelines, overt and subclinical thyroid dysfunction are mentioned as causal and treatable factors for cognitive decline. However, the scientific literature on these associations shows inconsistent findings.OBJECTIVE To assess cross-sectional and longitudinal associations of baseline thyroid dysfunction with cognitive function and dementia.DESIGN, SETTING, AND PARTICIPANTS This multicohort individual participant data analysis assessed 114 267 person-years (median, 1.7-11.3 years) of follow-up for cognitive function and 525 222 person-years (median, 3.8-15.3 years) for dementia between 1989 and 2017. Analyses on cognitive function included 21 cohorts comprising 38 144 participants. Analyses on dementia included eight cohorts with a total of 2033 cases with dementia and 44 573 controls. Data analysis was performed from December 2016 to January 2021.EXPOSURES Thyroid function was classified as overt hyperthyroidism, subclinical hyperthyroidism, euthyroidism, subclinical hypothyroidism, and overt hypothyroidism based on uniform thyrotropin cutoff values and study-specific free thyroxine values.MAIN OUTCOMES AND MEASURES The primary outcome was global cognitive function, mostly measured using the Mini-Mental State Examination. Executive function, memory, and dementia were secondary outcomes. Analyses were first performed at study level using multivariable linear regression and multivariable Cox regression, respectively. The studies were combined with restricted maximum likelihood meta-analysis. To overcome the use of different scales, results were transformed to standardized mean differences. For incident dementia, hazard ratios were calculated.RESULTS Among 74 565 total participants, 66 567 (89.3%) participants had normal thyroid function, 577 (0.8%) had overt hyperthyroidism, 2557 (3.4%) had subclinical hyperthyroidism, 4167 (5.6%) had subclinical hypothyroidism, and 697 (0.9%) had overt hypothyroidism. The
- Published
- 2021
12. Association of Thyroid Dysfunction with Cognitive Function:An Individual Participant Data Analysis
- Author
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Van Vliet, Nicolien A., Van Heemst, Diana, Almeida, Osvaldo P., Åsvold, Bjørn O., Aubert, Carole E., Bae, Jong Bin, Barnes, Linda E., Bauer, Douglas C., Blauw, Gerard J., Brayne, Carol, Cappola, Anne R., Ceresini, Graziano, Comijs, Hannie C., Dartigues, Jean Francois, Degryse, Jean Marie, Dullaart, Robin P.F., Van Eersel, Marlise E.A., Den Elzen, Wendy P.J., Ferrucci, Luigi, Fink, Howard A., Flicker, Leon, Grabe, Hans J., Han, Ji Won, Helmer, Catherine, Huisman, Martijn, Ikram, M. Arfan, Imaizumi, Misa, De Jongh, Renate T., Jukema, J. Wouter, Kim, Ki Woong, Kuller, Lewis H., Lopez, Oscar L., Mooijaart, Simon P., Moon, Jae Hoon, Moutzouri, Elisavet, Nauck, Matthias, Parle, Jim, Peeters, Robin P., Samuels, Mary H., Schmidt, Carsten O., Schminke, Ulf, Slagboom, P. Eline, Stordal, Eystein, Vaes, Bert, Völzke, Henry, Westendorp, Rudi G.J., Yamada, Michiko, Yeap, Bu B., Rodondi, Nicolas, Gussekloo, Jacobijn, Trompet, Stella, Van Vliet, Nicolien A., Van Heemst, Diana, Almeida, Osvaldo P., Åsvold, Bjørn O., Aubert, Carole E., Bae, Jong Bin, Barnes, Linda E., Bauer, Douglas C., Blauw, Gerard J., Brayne, Carol, Cappola, Anne R., Ceresini, Graziano, Comijs, Hannie C., Dartigues, Jean Francois, Degryse, Jean Marie, Dullaart, Robin P.F., Van Eersel, Marlise E.A., Den Elzen, Wendy P.J., Ferrucci, Luigi, Fink, Howard A., Flicker, Leon, Grabe, Hans J., Han, Ji Won, Helmer, Catherine, Huisman, Martijn, Ikram, M. Arfan, Imaizumi, Misa, De Jongh, Renate T., Jukema, J. Wouter, Kim, Ki Woong, Kuller, Lewis H., Lopez, Oscar L., Mooijaart, Simon P., Moon, Jae Hoon, Moutzouri, Elisavet, Nauck, Matthias, Parle, Jim, Peeters, Robin P., Samuels, Mary H., Schmidt, Carsten O., Schminke, Ulf, Slagboom, P. Eline, Stordal, Eystein, Vaes, Bert, Völzke, Henry, Westendorp, Rudi G.J., Yamada, Michiko, Yeap, Bu B., Rodondi, Nicolas, Gussekloo, Jacobijn, and Trompet, Stella
- Abstract
Importance: In clinical guidelines, overt and subclinical thyroid dysfunction are mentioned as causal and treatable factors for cognitive decline. However, the scientific literature on these associations shows inconsistent findings. Objective: To assess cross-sectional and longitudinal associations of baseline thyroid dysfunction with cognitive function and dementia. Design, Setting, and Participants: This multicohort individual participant data analysis assessed 114267 person-years (median, 1.7-11.3 years) of follow-up for cognitive function and 525222 person-years (median, 3.8-15.3 years) for dementia between 1989 and 2017. Analyses on cognitive function included 21 cohorts comprising 38144 participants. Analyses on dementia included eight cohorts with a total of 2033 cases with dementia and 44573 controls. Data analysis was performed from December 2016 to January 2021. Exposures: Thyroid function was classified as overt hyperthyroidism, subclinical hyperthyroidism, euthyroidism, subclinical hypothyroidism, and overt hypothyroidism based on uniform thyrotropin cutoff values and study-specific free thyroxine values. Main Outcomes and Measures: The primary outcome was global cognitive function, mostly measured using the Mini-Mental State Examination. Executive function, memory, and dementia were secondary outcomes. Analyses were first performed at study level using multivariable linear regression and multivariable Cox regression, respectively. The studies were combined with restricted maximum likelihood meta-analysis. To overcome the use of different scales, results were transformed to standardized mean differences. For incident dementia, hazard ratios were calculated. Results: Among 74565 total participants, 66567 (89.3%) participants had normal thyroid function, 577 (0.8%) had overt hyperthyroidism, 2557 (3.4%) had subclinical hyperthyroidism, 4167 (5.6%) had subclinical hypothyroidism, and 697 (0.9%) had overt hypothyroidism. The study-specific median age at b
- Published
- 2021
13. Sleep characteristics across the lifespan in 1.1 million people from the Netherlands, United Kingdom and United States: a systematic review and meta-analysis
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Planetary Health & Exposoom, Circulatory Health, Public Health Epidemiologie, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Cluster Onderzoek, Kocevska, Desana, Lysen, Thom S, Dotinga, Aafje, Koopman-Verhoeff, M Elisabeth, Luijk, Maartje P C M, Antypa, Niki, Biermasz, Nienke R, Blokstra, Anneke, Brug, Johannes, Burk, Wiliam J, Comijs, Hannie C, Corpeleijn, Eva, Dashti, Hassan S, de Bruin, Eduard J, de Graaf, Ron, Derks, Ivonne P M, Dewald-Kaufmann, Julia F, Elders, Petra J M, Gemke, Reinoldus J B J, Grievink, Linda, Hale, Lauren, Hartman, Catharina A, Heijnen, Cobi J, Huisman, Martijn, Huss, Anke, Ikram, M Arfan, Jones, Samuel E, Velderman, Mariska Klein, Koning, Maaike, Meijer, Anne Marie, Meijer, Kim, Noordam, Raymond, Oldehinkel, Albertine J, Groeniger, Joost Oude, Penninx, Brenda W J H, Picavet, H Susan J, Pieters, Sara, Reijneveld, Sijmen A, Reitz, Ellen, Renders, Carry M, Rodenburg, Gerda, Rutters, Femke, Smith, Matt C, Singh, Amika S, Snijder, Marieke B, Stronks, Karien, Ten Have, Margreet, Twisk, Jos W R, Van de Mheen, Dike, van der Ende, Jan, van der Heijden, Kristiaan B, van der Velden, Peter G, van Lenthe, Frank J, van Litsenburg, Raphaële R L, van Oostrom, Sandra H, van Schalkwijk, Frank J, Sheehan, Connor M, Verheij, Robert A, Verhulst, Frank C, Vermeulen, Marije C M, Vermeulen, Roel C H, Verschuren, W M Monique, Vrijkotte, Tanja G M, Wijga, Alet H, Willemen, Agnes M, Ter Wolbeek, Maike, Wood, Andrew R, Xerxa, Yllza, Bramer, Wichor M, Franco, Oscar H, Luik, Annemarie I, Van Someren, Eus J W, Tiemeier, Henning, Planetary Health & Exposoom, Circulatory Health, Public Health Epidemiologie, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Cluster Onderzoek, Kocevska, Desana, Lysen, Thom S, Dotinga, Aafje, Koopman-Verhoeff, M Elisabeth, Luijk, Maartje P C M, Antypa, Niki, Biermasz, Nienke R, Blokstra, Anneke, Brug, Johannes, Burk, Wiliam J, Comijs, Hannie C, Corpeleijn, Eva, Dashti, Hassan S, de Bruin, Eduard J, de Graaf, Ron, Derks, Ivonne P M, Dewald-Kaufmann, Julia F, Elders, Petra J M, Gemke, Reinoldus J B J, Grievink, Linda, Hale, Lauren, Hartman, Catharina A, Heijnen, Cobi J, Huisman, Martijn, Huss, Anke, Ikram, M Arfan, Jones, Samuel E, Velderman, Mariska Klein, Koning, Maaike, Meijer, Anne Marie, Meijer, Kim, Noordam, Raymond, Oldehinkel, Albertine J, Groeniger, Joost Oude, Penninx, Brenda W J H, Picavet, H Susan J, Pieters, Sara, Reijneveld, Sijmen A, Reitz, Ellen, Renders, Carry M, Rodenburg, Gerda, Rutters, Femke, Smith, Matt C, Singh, Amika S, Snijder, Marieke B, Stronks, Karien, Ten Have, Margreet, Twisk, Jos W R, Van de Mheen, Dike, van der Ende, Jan, van der Heijden, Kristiaan B, van der Velden, Peter G, van Lenthe, Frank J, van Litsenburg, Raphaële R L, van Oostrom, Sandra H, van Schalkwijk, Frank J, Sheehan, Connor M, Verheij, Robert A, Verhulst, Frank C, Vermeulen, Marije C M, Vermeulen, Roel C H, Verschuren, W M Monique, Vrijkotte, Tanja G M, Wijga, Alet H, Willemen, Agnes M, Ter Wolbeek, Maike, Wood, Andrew R, Xerxa, Yllza, Bramer, Wichor M, Franco, Oscar H, Luik, Annemarie I, Van Someren, Eus J W, and Tiemeier, Henning
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- 2021
14. Promotion of self-management in vulnerable older people: a narrative literature review of outcomes of the Chronic Disease Self-Management Program (CDSMP)
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Jonker, Angèle A. G. C., Comijs, Hannie C., Knipscheer, Kees C. P. M., and Deeg, Dorly J. H.
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- 2009
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15. Do employed and not employed 55 to 64-year-olds’ memory complaints relate to memory performance? A longitudinal cohort study
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Rijs, Kelly J., Comijs, Hannie C., van den Kommer, Tessa N., and Deeg, Dorly J. H.
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- 2013
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16. Vitamin D deficiency and course of frailty in a depressed older population
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Berg, K.S. van den, Arts, Matheus H.L., Collard, R.M., Brink, Rob H. S. van den, Comijs, Hannie C., Marijnissen, R.M., Oude Voshaar, R.C., Berg, K.S. van den, Arts, Matheus H.L., Collard, R.M., Brink, Rob H. S. van den, Comijs, Hannie C., Marijnissen, R.M., and Oude Voshaar, R.C.
- Abstract
Contains fulltext : 216704.pdf (Publisher’s version ) (Closed access)
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- 2020
17. Trends in the use of care among people aged 65–85 with cognitive impairment in the Netherlands
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Aaltonen, Mari, Raitanen, Jani, Comijs, Hannie, Broese van Groenou, Marjolein, Aaltonen, Mari, Raitanen, Jani, Comijs, Hannie, and Broese van Groenou, Marjolein
- Abstract
Observation of long-term trends within countries is needed to increase insight into how policy initiatives are reflected in the use of care over time in addition to individual determinants of care use. In the past decades, Dutch care policies have favoured homecare and reduced the availability of institutional care which extended the care responsibilities of formal and informal care-givers at home. This study investigates the changes in the use of informal and formal homecare, community services and residential care among cognitively impaired older adults over time in the Netherlands. In addition, of special interest here are the associations of the presence of a spouse, other family members or social network with care use, and the interdependency between the use of different types of care. The study employs the Longitudinal Aging Study Amsterdam (LASA) covering the years 1992–2012, analysed with generalised estimating equations. The data consisted of 1,022 observations gathered from 813 respondents aged 65–85. The respondents were cognitively impaired according to the age- and education-standardised Mini-Mental State Examination score. The analyses took into account several individual determinants of care use. The use of informal care and residential care decreased while the use of formal homecare and community services remained the same. Simultaneously, the proportion of those who did not use the studied care types increased. The contribution of partners in informal care decreased. Informal care and formal homecare use increasingly became complementary services. The findings suggest that the decreases in informal care and residential care have not been replaced by other types of care, as reflected in the increased number of persons receiving no care. Care policies should not rely excessively on the availability of informal help and should guarantee adequate formal help, especially for those in high need.
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- 2020
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18. Spousal Loss and Change in Cognitive Functioning: An Examination of Temporal Patterns and Gender Differences
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Woern, Jonathan, Comijs, Hannie, Aartsen, Marja, Woern, Jonathan, Comijs, Hannie, and Aartsen, Marja
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Objectives: The study investigates whether the disadvantaged position of men in the adverse consequences of widowhood for health and mortality also exists for changes in cognitive health. Methods: We used data of up to 1,269 men and women aged 65 years and older who participated in the Longitudinal Aging Study Amsterdam in 3-yearly assessments between 1992 and 2012 (5,123 person-observations). All were married and without cognitive impairment (Mini-Mental State Examination >= 24) at baseline and up to 419 lost their spouse. In fixed effects regression models, the effect of spousal loss on change in four domains of cognitive functioning was estimated independently of age-related cognitive change. Results: For women, a robust temporary decrease was found in the second year after spousal loss in the reasoning domain, but not in global cognitive functioning, processing speed, or memory. No robust effects were found for men. Discussion: Considering that only one cognitive domain was affected and effects were temporary, cognitive functioning seems rather robust to the experience of spousal loss. Despite men having often been reported to be in a disadvantaged position in other health domains, our analyses indicate no such pattern for cognitive functioning.
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- 2020
19. Sleep characteristics across the lifespan in 1.1 million people from the Netherlands, United Kingdom and United States:a systematic review and meta-analysis
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Kocevska, Desana, Lysen, Thom S, Dotinga, Aafje, Koopman-Verhoeff, M Elisabeth, Luijk, Maartje P C M, Antypa, Niki, Biermasz, Nienke R, Blokstra, Anneke, Brug, Johannes, Burk, Wiliam J, Comijs, Hannie C, Corpeleijn, Eva, Dashti, Hassan S, de Bruin, Eduard J, de Graaf, Ron, Derks, Ivonne P M, Dewald-Kaufmann, Julia F, Elders, Petra J M, Gemke, Reinoldus J B J, Grievink, Linda, Hale, Lauren, Hartman, Catharina A, Heijnen, Cobi J, Huisman, Martijn, Huss, Anke, Ikram, M Arfan, Jones, Samuel E, Velderman, Mariska Klein, Koning, Maaike, Meijer, Anne Marie, Meijer, Kim, Noordam, Raymond, Oldehinkel, Albertine J, Groeniger, Joost Oude, Penninx, Brenda W J H, Picavet, H Susan J, Pieters, Sara, Reijneveld, Sijmen A, Reitz, Ellen, Renders, Carry M, Rodenburg, Gerda, Rutters, Femke, Smith, Matt C, Singh, Amika S, Snijder, Marieke B, Stronks, Karien, Ten Have, Margreet, Twisk, Jos W R, Van de Mheen, Dike, van der Ende, Jan, van der Heijden, Kristiaan B, van der Velden, Peter G, van Lenthe, Frank J, van Litsenburg, Raphaële R L, van Oostrom, Sandra H, van Schalkwijk, Frank J, Sheehan, Connor M, Verheij, Robert A, Verhulst, Frank C, Vermeulen, Marije C M, Vermeulen, Roel C H, Verschuren, W M Monique, Vrijkotte, Tanja G M, Wijga, Alet H, Willemen, Agnes M, Ter Wolbeek, Maike, Wood, Andrew R, Xerxa, Yllza, Bramer, Wichor M, Franco, Oscar H, Luik, Annemarie I, Van Someren, Eus J W, Tiemeier, Henning, Kocevska, Desana, Lysen, Thom S, Dotinga, Aafje, Koopman-Verhoeff, M Elisabeth, Luijk, Maartje P C M, Antypa, Niki, Biermasz, Nienke R, Blokstra, Anneke, Brug, Johannes, Burk, Wiliam J, Comijs, Hannie C, Corpeleijn, Eva, Dashti, Hassan S, de Bruin, Eduard J, de Graaf, Ron, Derks, Ivonne P M, Dewald-Kaufmann, Julia F, Elders, Petra J M, Gemke, Reinoldus J B J, Grievink, Linda, Hale, Lauren, Hartman, Catharina A, Heijnen, Cobi J, Huisman, Martijn, Huss, Anke, Ikram, M Arfan, Jones, Samuel E, Velderman, Mariska Klein, Koning, Maaike, Meijer, Anne Marie, Meijer, Kim, Noordam, Raymond, Oldehinkel, Albertine J, Groeniger, Joost Oude, Penninx, Brenda W J H, Picavet, H Susan J, Pieters, Sara, Reijneveld, Sijmen A, Reitz, Ellen, Renders, Carry M, Rodenburg, Gerda, Rutters, Femke, Smith, Matt C, Singh, Amika S, Snijder, Marieke B, Stronks, Karien, Ten Have, Margreet, Twisk, Jos W R, Van de Mheen, Dike, van der Ende, Jan, van der Heijden, Kristiaan B, van der Velden, Peter G, van Lenthe, Frank J, van Litsenburg, Raphaële R L, van Oostrom, Sandra H, van Schalkwijk, Frank J, Sheehan, Connor M, Verheij, Robert A, Verhulst, Frank C, Vermeulen, Marije C M, Vermeulen, Roel C H, Verschuren, W M Monique, Vrijkotte, Tanja G M, Wijga, Alet H, Willemen, Agnes M, Ter Wolbeek, Maike, Wood, Andrew R, Xerxa, Yllza, Bramer, Wichor M, Franco, Oscar H, Luik, Annemarie I, Van Someren, Eus J W, and Tiemeier, Henning
- Abstract
We aimed to obtain reliable reference charts for sleep duration, estimate the prevalence of sleep complaints across the lifespan and identify risk indicators of poor sleep. Studies were identified through systematic literature search in Embase, Medline and Web of Science (9 August 2019) and through personal contacts. Eligible studies had to be published between 2000 and 2017 with data on sleep assessed with questionnaires including ≥100 participants from the general population. We assembled individual participant data from 200,358 people (aged 1-100 years, 55% female) from 36 studies from the Netherlands, 471,759 people (40-69 years, 55.5% female) from the United Kingdom and 409,617 people (≥18 years, 55.8% female) from the United States. One in four people slept less than age-specific recommendations, but only 5.8% slept outside of the 'acceptable' sleep duration. Among teenagers, 51.5% reported total sleep times (TST) of less than the recommended 8-10 h and 18% report daytime sleepiness. In adults (≥18 years), poor sleep quality (13.3%) and insomnia symptoms (9.6-19.4%) were more prevalent than short sleep duration (6.5% with TST < 6 h). Insomnia symptoms were most frequent in people spending ≥9 h in bed, whereas poor sleep quality was more frequent in those spending <6 h in bed. TST was similar across countries, but insomnia symptoms were 1.5-2.9 times higher in the United States. Women (≥41 years) reported sleeping shorter times or slightly less efficiently than men, whereas with actigraphy they were estimated to sleep longer and more efficiently than man. This study provides age- and sex-specific population reference charts for sleep duration and efficiency which can help guide personalized advice on sleep length and preventive practices.
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- 2020
20. Attention-deficit hyperactivity disorder across the lifespan
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Xenitidis, Kiriakos, Campbell, Colin, Michielsen, Marieke, Semeijn, Evert, Comijs, Hannie C., Beekman, Aartjan, and Kooij, Sandra
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- 2013
21. Prevalence of attention-deficit hyperactivity disorder in older adults in The Netherlands
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Michielsen, Marieke, Semeijn, Evert, Comijs, Hannie C., van de Ven, Peter, Beekman, Aartjan T. F., Deeg, Dorly J. H., and Kooij, J. J. Sandra
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- 2012
22. A NEO-PI-R short form for older adults
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Mooi, Bianca, Comijs, Hannie C., De Fruyt, Filip, De Ritter, Dineke, Hoekstra, Hans A., and Beekman, Aartjan T. F.
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- 2011
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23. Contribution of Metabolic Syndrome Components to Cognition in Older Individuals
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DIK, MIRANDA G., JONKER, CEES, COMIJS, HANNIE C., DEEG, DORLY J.H., KOK, ASTRID, YAFFE, KRISTINE, and PENNINX, BRENDA W.
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- 2007
24. Target groups for the prevention of late – life anxiety
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SMIT, FILIP, COMIJS, HANNIE, SCHOEVERS, ROBERT, CUIJPERS, PIM, DEEG, DORLY, and BEEKMAN, AARTJAN
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- 2007
25. Disaster and associated changes in physical and mental health in older residents
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Deeg, Dorly J.H., Huizink, Anja C., Comijs, Hannie C., and Smid, Tjabe
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- 2005
26. Maintaining cognitive function with internet use : A two-country, six-year longitudinal study
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Berner, Jessica, Comijs, Hannie, Elmståhl, Sölve, Welmer, Anna Karin, Sanmartin Berglund, Johan, Anderberg, Peter, Deeg, Dorly, Berner, Jessica, Comijs, Hannie, Elmståhl, Sölve, Welmer, Anna Karin, Sanmartin Berglund, Johan, Anderberg, Peter, and Deeg, Dorly
- Abstract
Objectives: Maintaining good cognitive function with aging may be aided by technology such as computers, tablets, and their applications. Little research so far has investigated whether internet use helps to maintain cognitive function over time.Design: Two population-based studies with a longitudinal design from 2001/2003 (T1) to 2007/2010 (T2).Setting: Sweden and the Netherlands.Participants: Older adults aged 66 years and above from the Swedish National Study on Ageing and Care (N = 2,564) and from the Longitudinal Aging Study Amsterdam (N = 683).Measurements: Internet use was self-reported. Using the scores from the Mini-Mental State Examination (MMSE) from T1 and T2, both a difference score and a significant change index was calculated. Linear and logistic regression analysis were performed with difference score and significant change index, respectively, as the dependent variable and internet use as the independent variable, and adjusted for sex, education, age, living situation, and functional limitations. Using a meta-analytic approach, summary coefficients were calculated across both studies.Results: Internet use at baseline was 26.4% in Sweden and 13.3% in the Netherlands. Significant cognitive decline over six years amounted to 9.2% in Sweden and 17.0% in the Netherlands. Considering the difference score, the summary linear regression coefficient for internet use was-0.32 (95% CI:-0.62,-0.02). Considering the significant change index, the summary odds ratio for internet use was 0.54 (95% CI: 0.37, 0.78).Conclusions: The results suggest that internet use might play a role in maintaining cognitive functioning. Further research into the specific activities that older adults are doing on the internet may shine light on this issue. © 2019 International Psychogeriatric Association., open access
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- 2019
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27. A healthy lifestyle in old age and prospective change in four domains of functioning
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Visser, Marjolein, Wijnhoven, H.A.H., Comijs, Hannie C., Thomese, Fleur, Twisk, J.W.R., Deeg, Dorly J.H., Visser, Marjolein, Wijnhoven, H.A.H., Comijs, Hannie C., Thomese, Fleur, Twisk, J.W.R., and Deeg, Dorly J.H.
- Abstract
Objective: The aim of this article is to study the associations between healthy lifestyle in old age and decline in physical, psychological, cognitive, and social functioning. Method: A population-based sample of 3,107 Dutch men and women aged 55 and 85 years (1992/1993; Longitudinal Aging Study Amsterdam) was used with five 3-yeary follow-up examinations. Lifestyle score, based on smoking status, alcohol consumption, physical activity, and body mass index (BMI), ranged from 0 (unhealthy) to 4 (healthy). Outcomes included gait speed, depressive symptoms, cognitive status, and social contacts. Results: Persons with a healthy lifestyle had a 10.6% slower decline in gait speed (0.04 m/s, 95% confidence interval [CI] = [0.03, 0.05]), 10.8% slower increase in depressive symptoms (–1.07 [–1.70, –0.44]), a 1.8% slower decline in cognitive functioning (0.47 [0.23, 0.70]), and a 4.9% slower decline in social contacts (0.58 [0.01, 1.15]) compared with persons with no or one healthy lifestyle factor. Discussion: A healthy lifestyle benefits physical, psychological, cognitive, and social functioning up to very old age.
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- 2019
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28. Anxiety and the risk of death in older men and women
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VAN HOUT, HEIN P. J., BEEKMAN, AARTJAN T. F., DE BEURS, EDWIN, COMIJS, HANNIE, VAN MARWIJK, HARM, DE HAAN, MARTEN, VAN TILBURG, WILLEM, and DEEG, DORLY J. H.
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- 2004
29. Het neuropsychologisch onderzoek
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Comijs, Hannie, Van den Stock, Jan, Oude Voshaar, Richard, van der Mast, Roos, Stek, Max, Verhey, Frans, and Vandenbulcke, Mathieu
- Abstract
ispartof: Handboek ouderenpsychiatrie pages:221-236 ispartof: pages:221-236 status: published
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- 2018
30. Cohort differences in cognitive aging in the longitudinal aging study Amsterdam
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Brailean, Anamaria, Huisman, Martijn, Prince, Martin, Matthew Prina, Deeg, Dorly J. H., Comijs, Hannie, Epidemiology and Data Science, APH - Aging & Later Life, APH - Societal Participation & Health, Psychiatry, APH - Mental Health, Sociology, and The Social Context of Aging (SoCA)
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Journal Article ,SDG 4 - Quality Education - Abstract
OBJECTIVES: This study aims to examine cohort differences in cognitive performance and rates of change in episodic memory, processing speed, inductive reasoning, and general cognitive performance and to investigate whether these cohort effects may be accounted for by education attainment.METHOD: The first cohort (N = 705) was born between 1920 and 1930, whereas the second cohort (N = 646) was born between 1931 and 1941. Both birth cohorts were aged 65 to 75 years at baseline and were followed up 3 and 6 years later. Data were analyzed using linear mixed models.RESULTS: The later born cohort had better general cognitive performance, inductive reasoning, and processing speed at baseline, but cohort differences in inductive reasoning and general cognitive performance disappeared after adjusting for education. The later born cohort showed steeper decline in processing speed. Memory decline was steeper in the earlier born cohort but only from Time 1 to Time 3 when the same memory test was administered. Education did not account for cohort differences in cognitive decline.DISCUSSION: The later born cohort showed better initial performance in certain cognitive abilities, but no better preservation of cognitive abilities overtime compared with the earlier born cohort. These findings carry implications for healthy cognitive aging.
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- 2018
31. Trends across 20 years in multiple indicators of functioning among older adults in the Netherlands
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Timmermans, Erik J, primary, Hoogendijk, Emiel O, additional, Broese van Groenou, Marjolein I, additional, Comijs, Hannie C, additional, van Schoor, Natasja M, additional, Thomése, Fleur C F, additional, Visser, Marjolein, additional, Deeg, Dorly J H, additional, and Huisman, Martijn, additional
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- 2019
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32. The Netherlands study of depression in older persons (NESDO); a prospective cohort study
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Comijs Hannie C, van Marwijk Harm W, van der Mast Roos C, Naarding Paul, Oude Voshaar Richard C, Beekman Aartjan TF, Boshuisen Marjolein, Dekker Janny, Kok Rob, de Waal Margot WM, Penninx Brenda WJH, Stek Max L, and Smit Johannes H
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Medicine ,Biology (General) ,QH301-705.5 ,Science (General) ,Q1-390 - Abstract
Abstract Background To study late-life depression and its unfavourable course and co morbidities in The Netherlands. Methods We designed the Netherlands Study of Depression in Older Persons (NESDO), a multi-site naturalistic prospective cohort study which makes it possible to examine the determinants, the course and the consequences of depressive disorders in older persons over a period of six years, and to compare these with those of depression earlier in adulthood. Results From 2007 until 2010, the NESDO consortium has recruited 510 depressed and non depressed older persons (≥ 60 years) at 5 locations throughout the Netherlands. Depressed persons were recruited from both mental health care institutes and general practices in order to include persons with late-life depression in various developmental and severity stages. Non-depressed persons were recruited from general practices. The baseline assessment included written questionnaires, interviews, a medical examination, cognitive tests and collection of blood and saliva samples. Information was gathered about mental health outcomes and demographic, psychosocial, biological, cognitive and genetic determinants. The baseline NESDO sample consists of 378 depressed (according to DSM-IV criteria) and 132 non-depressed persons aged 60 through 93 years. 95% had a major depression and 26.5% had dysthymia. Mean age of onset of the depressive disorder was around 49 year. For 33.1% of the depressed persons it was their first episode. 41.0% of the depressed persons had a co morbid anxiety disorder. Follow up assessments are currently going on with 6 monthly written questionnaires and face-to-face interviews after 2 and 6 years. Conclusions The NESDO sample offers the opportunity to study the neurobiological, psychosocial and physical determinants of depression and its long-term course in older persons. Since largely similar measures were used as in the Netherlands Study of Depression and Anxiety (NESDA; age range 18-65 years), data can be pooled thus creating a large longitudinal database of clinically depressed persons with adequate power and a large set of neurobiological, psychosocial and physical variables from both younger and older depressed persons.
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- 2011
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33. A Six-Year Prospective Study of the Prognosis and Predictors in Patients With Late-Life Depression
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Jeuring, H.W., Stek, Max L., Huisman, Martijn, Oude Voshaar, R.C., Naarding, Paul, Collard, R.M., Kok, R.M.D., Beekman, A.T.F., Comijs, Hannie C., Jeuring, H.W., Stek, Max L., Huisman, Martijn, Oude Voshaar, R.C., Naarding, Paul, Collard, R.M., Kok, R.M.D., Beekman, A.T.F., and Comijs, Hannie C.
- Abstract
Contains fulltext : 195151.pdf (publisher's version ) (Closed access)
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- 2018
34. Leucocyte telomere length is no molecular marker of physical frailty in late-life depression
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Arts, Matheus H.L., Collard, R.M., Comijs, Hannie C., Jonge, Linda de, Penninx, Brenda W.J.H., Naarding, Paul, Kok, R.M.D., Oude Voshaar, R.C., Arts, Matheus H.L., Collard, R.M., Comijs, Hannie C., Jonge, Linda de, Penninx, Brenda W.J.H., Naarding, Paul, Kok, R.M.D., and Oude Voshaar, R.C.
- Abstract
Contains fulltext : 195272.pdf (publisher's version ) (Closed access)
- Published
- 2018
35. Vitamin D Status and Depressive Symptoms in Older Adults: A Role for Physical Functioning?
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de Koning, Elisa J., Elstgeest, Liset E.M., Comijs, Hannie C., Lips, Paul, Rijnhart, Judith J.M., van Marwijk, Harm W.J., Beekman, Aartjan T.F., Visser, Marjolein, Penninx, Brenda W.J.H., van Schoor, Natasja M., de Koning, Elisa J., Elstgeest, Liset E.M., Comijs, Hannie C., Lips, Paul, Rijnhart, Judith J.M., van Marwijk, Harm W.J., Beekman, Aartjan T.F., Visser, Marjolein, Penninx, Brenda W.J.H., and van Schoor, Natasja M.
- Abstract
Objectives: Depressive symptoms and low vitamin D status are common in older persons and may be associated, but findings are inconsistent. This study investigated whether 25-hydroxyvitamin D (25(OH)D) concentrations are associated with depressive symptoms in older adults, both cross-sectionally and longitudinally. We also examined whether physical functioning could explain this relationship, to gain a better understanding of the underlying mechanisms. Methods: Data from two independent prospective cohorts of the Longitudinal Aging Study Amsterdam were used: an older cohort (≥65 years, n = 1282, assessed from 1995–2002) and a younger-old cohort (55–65 years, n = 737, assessed from 2002–2009). Measurements: Depressive symptoms were measured at baseline and after 3 and 6 years with the Center of Epidemiological Studies Depression Scale. Cross-sectional and longitudinal linear regression techniques were used to examine the relationship between 25(OH)D and depressive symptoms. The mediating role of physical functioning was examined in the longitudinal models. Results: Cross-sectionally, associations were not significant after adjustment for confounders. Longitudinally, women in the older cohort with baseline 25(OH)D concentrations up to 75 nmol/L experienced 175 to 24% more depressive symptoms in the following 6 years, compared with women with 25(OH)D concentrations >75 nmol/L. Reduced physical performance partially mediated this relationship. In men and in the younger-old cohort, no significant associations were observed. Conclusions: Older women showed an inverse relationship between 25(OH)D and depressive symptoms over time, which may partially be explained by declining physical functioning. Replication of these findings by future studies is needed.
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- 2018
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36. Secular trends in excess mortality of late-life depression
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Jeuring, Hans W., Comijs, Hannie C., Deeg, Dorly J.H., Hoogendijk, Emiel O., Beekman, Aartjan T.F., Stek, Max L., Huisman, Martijn, Jeuring, Hans W., Comijs, Hannie C., Deeg, Dorly J.H., Hoogendijk, Emiel O., Beekman, Aartjan T.F., Stek, Max L., and Huisman, Martijn
- Abstract
Background: Late-life depression is associated with premature mortality, however, little is known whether excess mortality rates of depression have changed over time. This study aims to identify and explain secular trends in excess mortality of major depressive disorder (MDD) and subthreshold depression (SUBD). Methods: Cohort-sequential-longitudinal study of 4084 community-dwelling older adults in the Netherlands based on data from the Longitudinal Aging Study Amsterdam (LASA). Six measurement cycles were included from 1992/93 until 2008/09, each linked to the overall 5-year mortality, covering a 16-year time span. MDD and SUBD were identified using a two-stage screening procedure with the Center for Epidemiological Studies Depression Scale and the Diagnostic Interview Schedule. Age and sex were covariates. Education, health and lifestyle factors, and use of antidepressants were included as putative explanatory factors. Generalized Estimating Equations was used to investigate the association between the interaction ‘Depression × Time’ and 5-year mortality, and to find explanatory factors for the trend. Results: A downward trend in excess mortality of MDD was found (OR =.92, 95%-CI:.85–.99, P =.04), adjusted for age and sex, which could not be explained by education, health and lifestyle factors, nor antidepressants use. Sex differences in the trend were not found (P =.77). No trend in excess mortality of SUBD was found (OR = 1.01, 95%-CI:.97–1.04, P =.65). Limitations: The findings do not imply a similar trend for other countries. Conclusions: The results indicate a favorable development in excess mortality of community-dwelling older adults with MDD, while those with SUBD do not show a clear trend in excess mortality.
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- 2018
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37. Secular trends in the prevalence of major and subthreshold depression among 55-64-year olds over 20 years
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Jeuring, Hans W., Comijs, Hannie C., Deeg, Dorly J.H., Stek, Max L., Huisman, Martijn, Beekman, Aartjan T.F., Jeuring, Hans W., Comijs, Hannie C., Deeg, Dorly J.H., Stek, Max L., Huisman, Martijn, and Beekman, Aartjan T.F.
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BACKGROUND: Studying secular trends in the exposure to risk and protective factors of depression and whether these trends are associated with secular trends in the prevalence of depression is important to estimate future healthcare demands and to identify targets for prevention.METHODS: Three birth cohorts of 55-64-year olds from the population-based Longitudinal Aging Study Amsterdam were examined using identical methods in 1992 (n = 944), 2002 (n = 964) and 2012 (n = 957). A two-stage screening design was used to identify subthreshold depression (SUBD) and major depressive disorder (MDD). Multinomial logistic regression analyses were used to identify secular trends in depression prevalence and to identify factors from the biopsychosocial domains of functioning that were associated with these trends.RESULTS: Compared with 1992, MDD became more prevalent in 2002 (OR 1.90, 95% CI 1.10-3.28, p = 0.022) and 2012 (OR 1.80, 95% CI 1.03-3.14, p = 0.039). This was largely attributable to an increase in the prevalence of chronic diseases and functional limitations. Socioeconomic and psychosocial improvements, including an increase in labor market participation, social support and mastery, hampered MDD rates to rise more and were also associated with a 32% decline of SUBD-rates in 2012 as compared with 2002 (OR 0.68, 95% CI 0.48-0.96, p = 0.03).CONCLUSIONS: Among late middle-aged adults, there is a substantial net increase of MDD, which is associated with deteriorating physical health. If morbidity and disability continue to increase, a further expansion of MDD rates may be expected. Improving socioeconomic and psychosocial conditions may benefit public health, as these factors were protective against a higher prevalence of both MDD and SUBD.
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- 2018
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38. A six-year prospective study of the prognosis and predictors in patients with late-life depression
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Jeuring, Hans W, Stek, Max L, Huisman, Martijn, Oude Voshaar, Richard C, Naarding, Paul, Collard, Rose M, van der Mast, Roos C, Kok, Rob M, Beekman, Aartjan T F, Comijs, Hannie C, Jeuring, Hans W, Stek, Max L, Huisman, Martijn, Oude Voshaar, Richard C, Naarding, Paul, Collard, Rose M, van der Mast, Roos C, Kok, Rob M, Beekman, Aartjan T F, and Comijs, Hannie C
- Abstract
OBJECTIVES: To examine the six-year prognosis of patients with late-life depression and to identify prognostic factors of an unfavorable course.DESIGN AND SETTING: The Netherlands Study of Depression in Older Persons (NESDO) is a multisite naturalistic prospective cohort study with six-year follow-up.PARTICIPANTS: Three hundred seventy-eight clinically depressed patients (according to Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition Text Revision criteria) and 132 nondepressed comparisons were included at baseline between 2007 and 2010.MEASUREMENTS: Depression was measured by the Inventory of Depressive Symptomatology at 6-month intervals and a diagnostic interview at 2- and 6-year follow-up. Multinomial regression and mixed model analyses were both used to identify depression-related clinical, health, and psychosocial prognostic factors of an unfavorable course.RESULTS: Among depressed patients at baseline, 46.8% were lost to follow-up; 15.9% had an unfavorable course, i.e., chronic or recurrent; 24.6% had partial remission; and 12.7% had full remission at six-year follow-up. The relative risk of mortality in depressed patients was 2.5 (95% confidence interval 1.26-4.81) versus nondepressed comparisons. An unfavorable course of depression was associated with a younger age at depression onset; higher symptom severity of depression, pain, and neuroticism; and loneliness at baseline. Additionally, partial remission was associated with chronic diseases and loneliness at baseline when compared with full remission.CONCLUSIONS: The long-term prognosis of late-life depression is poor with regard to mortality and course of depression. Chronic diseases, loneliness, and pain may be used as putative targets for optimizing prevention and treatment strategies for relapse and chronicity.
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- 2018
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39. 23-year trends in life expectancy in good and poor physical and cognitive health at age 65 years in the Netherlands, 1993-2016
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Deeg, Dorly J.H., Comijs, Hannie C., Hoogendijk, Emiel O., van der Noordt, Maaike, Huisman, Martijn, Deeg, Dorly J.H., Comijs, Hannie C., Hoogendijk, Emiel O., van der Noordt, Maaike, and Huisman, Martijn
- Abstract
OBJECTIVES: To examine 23-year trends in both physically and cognitively healthy life expectancy from age 65 years in the Netherlands. METHODS: We used 8 waves between 1993 and 2016 from the nationally representative Longitudinal Aging Study Amsterdam (12 948 observations). We calculated physically and cognitively healthy life expectancies by using the Sullivan life table method and tested prevalence trends over time by using generalized estimating equations. RESULTS: Total life expectancy at age 65 years rose from 14.7 to 18.7 years (men) and from 19.2 to 21.4 years (women). Life expectancy in poor physical health increased nonlinearly from 1.8 to 2.9 years for men; for women it fluctuated around 5.7 years. Meanwhile, life expectancy in good cognitive health increased linearly from 11.0 to 15.7 years (men) and from 13.4 to 18.0 years (women). The proportion of people with poor physical and poor cognitive health combined did not increase, averaging 5.9% (men) and 8.7% (women). CONCLUSIONS: This multiwave study shows that a negative trend in physically healthy life expectancy is accompanied by a positive trend in cognitively healthy life expectancy.
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- 2018
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40. Longitudinal associations between symptom dimensions of depression and cognitive functioning in the elderly
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Comijs, Hannie, Psychiatry, APH - Mental Health, and APH - Aging & Later Life
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- 2017
41. Additional file 1: Figure S1. of Economic evaluation of stepped-care versus usual care for depression and anxiety in older adults with vision impairment: randomized controlled trial
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Aa, Hilde, Rens, Ger, Bosmans, Judith, Comijs, Hannie, and Nispen, Ruth
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Cost-effectiveness planes and cost-efectiveness acceptability curves for the sensitivity analyses. (DOCX 56 kb)
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- 2017
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42. Modifiable Risk Factors for Prevention of Dementia in Midlife, Late Life and the Oldest-Old: Validation of the LIBRA Index
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Vos, Stephanie J. B., Vos, Stephanie J. B., van Boxtel, Martin P. J., Schiepers, Olga J. G., Deckers, Kay, de Vugt, Marjolein, Carriere, Isabelle, Dartigues, Jean-Francois, Peres, Karine, Artero, Sylvaine, Ritchie, Karen, Galluzzo, Lucia, Scafato, Emanuele, Frison, Giovanni B., Huisman, Martijn, Comijs, Hannie C., Sacuiu, Simona F., Skoog, Ingmar, Irving, Kate, O'Donnell, Catherine A., Verhey, Frans R. J., Visser, Pieter Jelle, Köhler, Sebastian, Vos, Stephanie J. B., Vos, Stephanie J. B., van Boxtel, Martin P. J., Schiepers, Olga J. G., Deckers, Kay, de Vugt, Marjolein, Carriere, Isabelle, Dartigues, Jean-Francois, Peres, Karine, Artero, Sylvaine, Ritchie, Karen, Galluzzo, Lucia, Scafato, Emanuele, Frison, Giovanni B., Huisman, Martijn, Comijs, Hannie C., Sacuiu, Simona F., Skoog, Ingmar, Irving, Kate, O'Donnell, Catherine A., Verhey, Frans R. J., Visser, Pieter Jelle, and Köhler, Sebastian
- Abstract
Background: Recently, the LIfestyle for BRAin health (LIBRA) index was developed to assess an individual’s prevention potential for dementia. Objective: We investigated the predictive validity of the LIBRA index for incident dementia in midlife, late life, and the oldest-old. Methods: 9,387 non-demented individuals were recruited from the European population-based DESCRIPA study. An individual’s LIBRA index was calculated solely based on modifiable risk factors: depression, diabetes, physical activity, hypertension, obesity, smoking, hypercholesterolemia, coronary heart disease, and mild/moderate alcohol use. Cox regression was used to test the predictive validity of LIBRA for dementia at follow-up (mean 7.2 y, range 1–16). Results: In midlife (55–69 y, n = 3,256) and late life (70–79 y, n = 4,320), the risk for dementia increased with higher LIBRA scores. Individuals in the intermediate- and high-risk groups had a higher risk of dementia than those in the low-risk group. In the oldest-old (80–97 y, n = 1,811), higher LIBRA scores did not increase the risk for dementia. Conclusion: LIBRA might be a useful tool to identify individuals for primary prevention interventions of dementia in midlife, and maybe in late life, but not in the oldest-old.
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- 2017
43. Economic evaluation of stepped-care versus usual care for depression and anxiety in older adults with vision impairment: randomized controlled trial
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van der Aa, Hilde P. A., primary, van Rens, Ger H. M. B., additional, Bosmans, Judith E., additional, Comijs, Hannie C., additional, and van Nispen, Ruth M. A., additional
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- 2017
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44. Presence and correlates of apathy in non-demented depressed and non-depressed older persons
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Groeneweg-Koolhoven, Isis, Comijs, Hannie C., Naarding, Paul, de Waal, Margot WM., and van der Mast, Roos C.
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Depressive disorder ,Apathy ,Amotivation ,Old age ,Human medicine ,Apathy determinants ,Geriatric - Abstract
Background and Objectives: Apathy is a behavioral syndrome that often co-occurs with depression. Nonetheless, the etiology of apathy and depression may be different. We hypothesized that apathy occurs more often in depressed compared to non-depressed older persons; and that independent correlates for apathy will be different in depressed and non-depressed older persons. Methods: In this cross-sectional study of Netherlands Study of Depression in Older Persons (NESDO), a total of 350 depressed older persons according to the Composite International Diagnostic Interview (CIDI) and 126 non-depressed older persons, aged at least 60 years were recruited in several Medical Centres and general practices. In both depressed and non-depressed older persons, those with and without apathy as assessed with the Apathy Scale (score >= 14) were compared with regard to socio-demographic, clinical, and biological characteristics. Results: Apathy was present in 75% of the depressed and 25% of the non-depressed older persons. Independent correlates of apathy in both depressed and non-depressed older persons were male gender and less education. Furthermore, in depressed older persons, higher scores on the Inventory of Depressive Symptomatology (IDS) and, in non-depressed older persons, a higher C-reactive protein (CRP) level correlated independently with apathy. Conclusions: Apathy occurred frequently among both depressed and non-depressed older persons. Among depressed older persons, apathy appeared to be a symptom of more serious depression, whereas among non-depressed persons apathy was associated with increased CRP being a marker for immune activation, suggesting a different aetiology for apathy in its own right.
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- 2015
45. Changes in admission to long-term care institutions in the Netherlands: comparing two cohorts over the period 1996–1999 and 2006–2009
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Alders, Peter, primary, Comijs, Hannie C., additional, and Deeg, Dorly J. H., additional
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- 2016
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46. Role of vision loss, functional limitations and the supporting network in depression in a general population
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van Nispen, Ruth M. A., primary, Vreeken, Hilde L., additional, Comijs, Hannie C., additional, Deeg, Dorly J. H., additional, and van Rens, Ger H. M. B., additional
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- 2015
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47. Economic evaluation of an e-mental health intervention for patients with retinal exudative diseases who receive intraocular anti-VEGF injections (E-PsEYE): protocol for a randomised controlled trial.
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van der Aa, Hilde P. A., van Rens, Ger H. M. B., Verbraak, Frank D., Bosscha, Machteld, Koopmanschap, Marc A., Comijs, Hannie C., Cuijpers, Pim, and van Nispen, Ruth M. A.
- Abstract
Introduction Because of the great potential of vascular endothelial growth factor inhibitors (anti-VEGF) for retinal exudative diseases, an increased number of patients receives this treatment. However, during this treatment, patients are subjected to frequent invasive intravitreal injections, and the effects on reversing the process of vision loss are uncertain, which may have negative consequences for patients' mental health. One in three patients experience at least mild symptoms of depression/anxiety. To support patients in dealing with these symptoms, an e-mental health intervention (called E-PsEYE) has been developed. E-PsEYE is based on cognitive-behavioural therapy (CBT) and contains nine modules. A stepped-care model with three steps will be used to deliver the intervention: (1) providing information and psychoeducation, (2) when symptoms of depression/anxiety persist, guided CBT is offered and supported by social workers from low vision rehabilitation services and (3) when symptoms still persist, patients are referred to their general practitioner. Methods and analysis An economic evaluation from a healthcare and societal perspective will be conducted alongside a multicentre randomised controlled trial in two parallel groups to evaluate whether E-PsEYE is cost-effective in comparison with usual care. Participants (n=174) will be 50 years or older, have retinal exudative diseases, receive anti-VEGF treatment and have mild symptoms of depression/anxiety (assessed prior to randomisation). Main outcome measures are: depression (Patient Health Questionnaire-9), anxiety (Hospital Anxiety and Depression Scale-Anxiety) and quality-adjusted life-years (determined with the Health Utility Index-3 and the EuroQol-5 dimensions). Five measurements take place: at baseline and after 3, 6, 9 and 12 months. Ethics and dissemination The study has been approved by the Medical Ethics Committee of the VU University Medical Centre Amsterdam. It will provide new and essential information on the cost-effectiveness of an innovative intervention for a vulnerable population. Outcomes will be disseminated through peer-reviewed publications and conference presentations. [ABSTRACT FROM AUTHOR]
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- 2017
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48. Benefits for elders with vulnerable health from the Chronic Disease Self-management Program (CDSMP) at short and longer term
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Jonker, Angèle A. G. C., primary, Comijs, Hannie C., additional, Knipscheer, Kees C. P. M., additional, and Deeg, Dorly J. H., additional
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- 2015
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49. Prevalence and Incidence of Memory Complaints in Employed Compared to Non-Employed Aged 55–64 Years and the Role of Employment Characteristics
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Rijs, Kelly J., primary, Van den Kommer, Tessa N., additional, Comijs, Hannie C., additional, and Deeg, Dorly J. H., additional
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- 2015
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50. The two-year course of late-life depression; results from the Netherlands study of depression in older persons
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Comijs, Hannie C, primary, Nieuwesteeg, Jasper, additional, Kok, Rob, additional, van Marwijk, Harm W, additional, van der Mast, Roos C, additional, Naarding, Paul, additional, Voshaar, Richard C Oude, additional, Verhaak, Peter, additional, de Waal, Margot WM, additional, and Stek, Max L, additional
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- 2015
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