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1. Characterization of microsatellite polymorphisms DXS691 and DXS692: genetic mapping to Xq26.2-Xq27 and Xq25-Xq26.2

Author

T. G. Nygaard, Umadevi Tantravahi, Daniel M. Lasser, and Kirk C. Wilhelmsen

Subjects
Genetics, Polymorphism, Genetic, X Chromosome, Base Sequence, Molecular Sequence Data, Chromosome Mapping, Biology, DNA, Satellite, Loss of heterozygosity, Gene mapping, Genetic marker, Genetic linkage, Cricetinae, Microsatellite, Animals, Chromosomes, Human, Humans, Restriction fragment length polymorphism, Allele frequency, X chromosome, Repetitive Sequences, Nucleic Acid
Abstract

Simple sequence repeat microsatellite polymorphisms are extremely useful markers for resolutional enhancement of human genetic linkage maps due to the existence of multiple alleles and a high degree of heterozygosity. The authors have identified and characterized two polymorphic CA-dinucleotide repeats and have determined their positional assignment on the X chromosome by genetic and physical mapping. 14 refs., 1 tab.

Published
1993

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