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212 results on '"Diterpenes chemical synthesis"'

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1. Biologically active franchetine-type diterpenoid alkaloids: Isolation, synthesis, anti-inflammatory, agalgesic activities, and molecular docking.

2. Design, synthesis, and in vivo and in vitro biological screening of pseudolaric acid B derivatives as potential anti-tumor agents.

3. Sphaerococcenol A Derivatives: Design, Synthesis, and Cytotoxicity.

4. Structure-activity relationships of natural and synthetic lathyrane-based diterpenoids for suppression of NLRP3-driven inflammation and gouty arthritis.

5. Design, Synthesis, and Anticancer Activity of Novel Enmein-Type Diterpenoid Derivatives Targeting the PI3K/Akt/mTOR Signaling Pathway.

6. A general strategy for the synthesis of taxane diterpenes.

7. The catalytic asymmetric polyene cyclization of homofarnesol to ambrox.

8. Synthetic Modifications of Andrographolide Targeting New Potential Anticancer Drug Candidates: A Comprehensive Overview.

9. Lathyrane and premyrsinane Euphorbia diterpenes against Alzheimer's disease: Bioinspired synthesis, anti-cholinesterase and neuroprotection bioactivity.

10. Exploring the Anticancer Potential of Semisynthetic Derivatives of 7α-Acetoxy-6β-hydroxyroyleanone from Plectranthus sp.: An In Silico Approach.

11. Synthetic Study towards Providencin: Stereocontrolled Synthesis of the Furan-Substituted Cyclobutanol Segment.

12. Synthesis, antiproliferative and anti-MDR activities of lathyrane diterpene derivatives based on configuration inversion strategy.

13. Synthesis and Characterization of Andrographolide Derivatives as Regulators of βAPP Processing in Human Cells.

14. Synthesis, biological activities and docking studies of pleuromutilin derivatives with piperazinyl urea linkage.

15. A click chemistry approach to pleuromutilin derivatives, evaluation of anti-MRSA activity and elucidation of binding mode by surface plasmon resonance and molecular docking.

16. Andrographolide: A Herbal-Chemosynthetic Approach for Enhancing Immunity, Combating Viral Infections, and Its Implication on Human Health.

17. Discovery of pseudolaric acid A as a new Hsp90 inhibitor uncovers its potential anticancer mechanism.

18. Design, synthesis, and anticancer evaluation of novel andrographolide derivatives bearing an α,β-unsaturated ketone moiety.

19. Design, synthesis, in vitro and in vivo evaluation against MRSA and molecular docking studies of novel pleuromutilin derivatives bearing 1, 3, 4-oxadiazole linker.

20. Diversity-oriented synthesis of cembranoid derivatives as potential anti-inflammatory agents.

21. Triptolide: pharmacological spectrum, biosynthesis, chemical synthesis and derivatives.

22. Design, synthesis and biological evaluation of novel pleuromutilin derivatives containing piperazine and 1,2,3-triazole linker.

23. Targeted degradation of CD147 proteins in melanoma.

24. Design, Synthesis and In Vitro Experimental Validation of Novel TRPV4 Antagonists Inspired by Labdane Diterpenes.

25. Mulinane- and Azorellane-Type Diterpenoids: A Systematic Review of Their Biosynthesis, Chemistry, and Pharmacology.

26. 2D Coordination Network of Trioxotriangulene with Multiple Redox Abilities and Its Rechargeable Battery Performance.

27. Total Syntheses of Marrubiin and Related Labdane Diterpene Lactones.

28. Synthesis and Evaluation of Anisomelic acid-like Compounds for the Treatment of HPV-Mediated Carcinomas.

29. Asymmetric Total Synthesis of (-)-Pavidolide B via a Thiyl-Radical-Mediated [3 + 2] Annulation Reaction.

30. A 16-step synthesis of the isoryanodane diterpene (+)-perseanol.

31. Synthesis and antitumor evaluation of neolaxiflorin B inspired compounds.

32. Combined Treatment with Triptolide and Tyrosine Kinase Inhibitors Synergistically Enhances Apoptosis in Non-small Cell Lung Cancer H1975 Cells but Not H1299 Cells through EGFR/Akt Pathway.

33. Total Synthesis of (-)-Pavidolide B: A Ring Contraction Strategy.

34. Peyssonnosides A-B, Unusual Diterpene Glycosides with a Sterically Encumbered Cyclopropane Motif: Structure Elucidation Using an Integrated Spectroscopic and Computational Workflow.

35. Euphosantianane E-G: Three New Premyrsinane Type Diterpenoids from Euphorbia sanctae-catharinae with Contribution to Chemotaxonomy.

36. Unified Enantioselective, Convergent Synthetic Approach toward the Furanobutenolide-Derived Polycyclic Norcembranoid Diterpenes: Synthesis of a Series of Ineleganoloids by Oxidation-State Manipulation of the Carbocyclic Core.

37. The Methylene-Cycloalkylacetate (MCA) Scaffold in Terpenyl Compounds with Potential Pharmacological Activities.

38. The digitization of organic synthesis.

39. Construction of a 6/5/9-membered tricyclic structure of cladiellins via radical-polar crossover reaction.

40. Stemarane Diterpenes and Diterpenoids.

41. Quaternary-centre-guided synthesis of complex polycyclic terpenes.

42. Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome.

43. Synthetic Studies on Enantioselective Total Synthesis of Cyathane Diterpenoids: Cyrneines A and B, Glaucopine C, and (+)-Allocyathin B 2 .

44. Bioactivity Profile of the Diterpene Isosteviol and its Derivatives.

45. Hydrogen sulfide releasing enmein-type diterpenoid derivatives as apoptosis inducers through mitochondria-related pathways.

46. Screening of novel HSP-inducing compounds to conserve cardiomyocyte function in experimental atrial fibrillation.

47. A Review on Bioactivities of Tobacco Cembranoid Diterpenes.

48. Biosynthesis of Grandione: An Example of Tandem Hetero Diels-Alder/Retro-Claisen Rearrangement Reaction?

49. Unified Total Synthesis, Stereostructural Elucidation, and Biological Evaluation of Sarcophytonolides.

50. Formal Total Synthesis of Actinoranone: Synthesis Approaches and Cytotoxic Studies.

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