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1. Unsupervised stratification of patients with myocardial infarction based on imaging and in-silico biomarkers

Author

Serra, Dolors, Romero, Pau, Franco, Paula, Bernat, Ignacio, Lozano, Miguel, Garcia-Fernandez, Ignacio, Soto, David, Berruezo, Antonio, Camara, Oscar, and Sebastian, Rafael

Subjects
Computer Science - Computational Engineering, Finance, and Science, Physics - Medical Physics
Abstract

This study presents a novel methodology for stratifying post-myocardial infarction patients at risk of ventricular arrhythmias using patient-specific 3D cardiac models derived from late gadolinium enhancement cardiovascular magnetic resonance (LGE-CMR) images. The method integrates imaging and computational simulation with a simplified cellular automaton model, Arrhythmic3D, enabling rapid and accurate VA risk assessment in clinical timeframes. Applied to 51 patients, the model generated thousands of personalized simulations to evaluate arrhythmia inducibility and predict VA risk. Key findings include the identification of slow conduction channels (SCCs) within scar tissue as critical to reentrant arrhythmias and the localization of high-risk zones for potential intervention. The Arrhythmic Risk Score (ARRISK), developed from simulation results, demonstrated strong concordance with clinical outcomes and outperformed traditional imaging-based risk stratification. The methodology is fully automated, requiring minimal user intervention, and offers a promising tool for improving precision medicine in cardiac care by enhancing patient-specific arrhythmia risk assessment and guiding treatment strategies.

Published
2024

2. A robust shape model for blood vessels analysis

Author

Romero, Pau, Pedrós, Abel, Sebastian, Rafael, Lozano, Miguel, and García-Fernández, Ignacio

Subjects
Computer Science - Computational Engineering, Finance, and Science, Physics - Medical Physics
Abstract

The availability of digital twins for the cardiovascular system will enable insightful computational tools both for research and clinical practice. This, however, demands robust and well defined models and methods for the different steps involved in the process. We present a vessel coordinate system (VCS) that enables the unanbiguous definition of locations in a vessel section, by adapting the idea of cylindrical coordinates to the vessel geometry. Using the VCS model, point correspondence can be defined among different samples of a cohort, allowing data transfer, quantitative comparison, shape coregistration or population analysis. Furthermore, the VCS model allows for the generation of specific meshes (e.g. cylindrical grids, ogrids) necessary for an accurate reconstruction of the geometries used in fluid simulations. We provide the technical details for coordinates computation and discuss the assumptions taken to guarantee that they are well defined. The VCS model is tested in a series of applications. We present a robust, low dimensional, patient specific vascular model and use it to study phenotype variability analysis of the thoracic aorta within a cohort of patients. Point correspondence is exploited to build an haemodynamics atlas of the aorta for the same cohort. The atlas originates from fluid simulations (Navier-Stokes with Finite Volume Method) conducted using OpenFOAMv10. We finally present a relevant discussion on the VCS model, which covers its impact in important areas such as shape modeling and computer fluids dynamics (CFD).

Published
2023

6. Common Sense Knowledge Learning for Open Vocabulary Neural Reasoning: A First View into Chronic Disease Literature

Author

Arroyo-Fernández, Ignacio, Sánchez-Rojas, José Armando, Tellez-Velázquez, Arturo, Juárez-Martínez, Flavio, Cruz-Barbosa, Raúl, Guzmán-Ramírez, Enrique, and Balderas-Martínez, Yalbi Itzel

Subjects
Computer Science - Computation and Language, Computer Science - Artificial Intelligence
Abstract

In this paper, we address reasoning tasks from open vocabulary Knowledge Bases (openKBs) using state-of-the-art Neural Language Models (NLMs) with applications in scientific literature. For this purpose, self-attention based NLMs are trained using a common sense KB as a source task. The NLMs are then tested on a target KB for open vocabulary reasoning tasks involving scientific knowledge related to the most prevalent chronic diseases (also known as non-communicable diseases, NCDs). Our results identified NLMs that performed consistently and with significance in knowledge inference for both source and target tasks. Furthermore, in our analysis by inspection we discussed the semantic regularities and reasoning capabilities learned by the models, while showing a first insight into the potential benefits of our approach to aid NCD research.

Published
2021

8. Broad sarbecovirus neutralization by combined memory B cell antibodies to ancestral SARS-CoV-2

Author

Planchais, Cyril, Fernández, Ignacio, Chalopin, Benjamin, Bruel, Timothée, Rosenbaum, Pierre, Beretta, Maxime, Dimitrov, Jordan D., Conquet, Laurine, Donati, Flora, Prot, Matthieu, Porrot, Françoise, Planas, Delphine, Staropoli, Isabelle, Guivel-Benhassine, Florence, Baquero, Eduard, van der Werf, Sylvie, Haouz, Ahmed, Simon-Lorière, Etienne, Montagutelli, Xavier, Maillère, Bernard, Rey, Félix A., Guardado-Calvo, Pablo, Nozach, Hervé, Schwartz, Olivier, and Mouquet, Hugo

Published
2024
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14. Comparison of Long-term Response and Remission to Omalizumab and Anti-IL-5/IL-5R Using Different Criteria in a Real-life Cohort of Severe Asthma Patients

Author

Valverde-Monge, Marcela, Sánchez-Carrasco, Patricia, Betancor, Diana, Barroso, Blanca, Rodrigo-Muñoz, José Manuel, Mahillo-Fernández, Ignacio, Arismendi, Ebymar, Bobolea, Irina, Cárdaba, Blanca, Cruz, María Jesús, Del Pozo, Victoria, Domínguez-Ortega, Javier, González-Barcala, Francisco Javier, Olaguibel, José María, Luna-Porta, Juan Alberto, Martínez-Rivera, Carlos, Mullol, Joaquim, Muñoz, Xavier, Peleteiro-Pedraza, Lorena, Picado Valles, Cesar, Plaza, Vicente, Quirce, Santiago, Rial, Manuel Jorge, Soto-Retes, Lorena, Valero, Antonio, and Sastre, Joaquín

Published
2024
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16. A synthetic delivery vector for mucosal vaccination

Author

Billet, Anne, Hadjerci, Justine, Tran, Thi, Kessler, Pascal, Ulmer, Jonathan, Mourier, Gilles, Ghazarian, Marine, Gonzalez, Anthony, Thai, Robert, Urquia, Pauline, Van Baelen, Anne-Cécile, Meola, Annalisa, Fernandez, Ignacio, Deville-Foillard, Stéphanie, MacDonald, Ewan, Paolini, Léa, Schmidt, Frédéric, Rey, Félix A., Kay, Michael S., Tartour, Eric, Servent, Denis, and Johannes, Ludger

Published
2023
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18. SARS-CoV-2 Omicron BA.1 breakthrough infection drives late remodeling of the memory B cell repertoire in vaccinated individuals

Author

Sokal, Aurélien, Barba-Spaeth, Giovanna, Hunault, Lise, Fernández, Ignacio, Broketa, Matteo, Meola, Annalisa, Fourati, Slim, Azzaoui, Imane, Vandenberghe, Alexis, Lagouge-Roussey, Pauline, Broutin, Manon, Roeser, Anais, Bouvier-Alias, Magali, Crickx, Etienne, Languille, Laetitia, Fournier, Morgane, Michel, Marc, Godeau, Bertrand, Gallien, Sébastien, Melica, Giovanna, Nguyen, Yann, Canoui-Poitrine, Florence, Pirenne, France, Megret, Jérôme, Pawlotsky, Jean-Michel, Fillatreau, Simon, Reynaud, Claude-Agnès, Weill, Jean-Claude, Rey, Félix A., Bruhns, Pierre, Mahévas, Matthieu, and Chappert, Pascal

Published
2023
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19. On the Possibility of Rewarding Structure Learning Agents: Mutual Information on Linguistic Random Sets

Author

Arroyo-Fernández, Ignacio, Carrasco-Ruíz, Mauricio, and Arias-Aguilar, J. Anibal

Subjects
Computer Science - Machine Learning, Computer Science - Artificial Intelligence, Computer Science - Computation and Language, Computer Science - Information Theory, Statistics - Machine Learning
Abstract

We present a first attempt to elucidate a theoretical and empirical approach to design the reward provided by a natural language environment to some structure learning agent. To this end, we revisit the Information Theory of unsupervised induction of phrase-structure grammars to characterize the behavior of simulated actions modeled as set-valued random variables (random sets of linguistic samples) constituting semantic structures. Our results showed empirical evidence of that simulated semantic structures (Open Information Extraction triplets) can be distinguished from randomly constructed ones by observing the Mutual Information among their constituents. This suggests the possibility of rewarding structure learning agents without using pretrained structural analyzers (oracle actors/experts)., Comment: Paper accepted to the Workshop on Sets & Partitions (NeurIPS 2019, Vancouver, Canada)

Published
2019

25. Unsupervised Sentence Representations as Word Information Series: Revisiting TF--IDF

Author

Arroyo-Fernández, Ignacio, Méndez-Cruz, Carlos-Francisco, Sierra, Gerardo, Torres-Moreno, Juan-Manuel, and Sidorov, Grigori

Subjects
Computer Science - Computation and Language
Abstract

Sentence representation at the semantic level is a challenging task for Natural Language Processing and Artificial Intelligence. Despite the advances in word embeddings (i.e. word vector representations), capturing sentence meaning is an open question due to complexities of semantic interactions among words. In this paper, we present an embedding method, which is aimed at learning unsupervised sentence representations from unlabeled text. We propose an unsupervised method that models a sentence as a weighted series of word embeddings. The weights of the word embeddings are fitted by using Shannon's word entropies provided by the Term Frequency--Inverse Document Frequency (TF--IDF) transform. The hyperparameters of the model can be selected according to the properties of data (e.g. sentence length and textual gender). Hyperparameter selection involves word embedding methods and dimensionalities, as well as weighting schemata. Our method offers advantages over existing methods: identifiable modules, short-term training, online inference of (unseen) sentence representations, as well as independence from domain, external knowledge and language resources. Results showed that our model outperformed the state of the art in well-known Semantic Textual Similarity (STS) benchmarks. Moreover, our model reached state-of-the-art performance when compared to supervised and knowledge-based STS systems.

Published
2017

26. Structures of the Foamy virus fusion protein reveal an unexpected link with the F protein of paramyxo-and pneumoviruses.

Author

Fernández, Ignacio, Bontems, François, Brun, Delphine, Youna Coquin, Goverde, Casper A., Correia, Bruno E., Gessain, Antoine, Buseyne, Florence, Rey, Felix A., and Backovic, Marija

Subjects
*HIV, *FOAMY viruses, *VIRAL envelopes, *CHIMERIC proteins, *MEMBRANE fusion
Abstract

Foamy viruses (FVs) constitute a subfamily of retroviruses. Their envelope (Env) glycoprotein drives the merger of viral and cellular membranes during entry into cells. The only available structures of retroviral Envs are those from human and simian immunodeficiency viruses from the subfamily of orthoretroviruses, which are only distantly related to the FVs. We report the cryo-electron microscopy structures of the FV Env ectodomain in the pre-and post-fusion states, which unexpectedly demonstrate structural similarity with the fusion protein (F) of paramyxo- and pneumoviruses, implying an evolutionary link between the viral fusogens. We describe the structural features that are unique to the FV Env and propose a mechanistic model for its conformational change, highlighting how the interplay of its structural elements could drive membrane fusion and viral entry. The structural knowledge on the FV Env now provides a framework for functional investigations, which can benefit the design of FV Env variants with improved features for use as gene therapy vectors. [ABSTRACT FROM AUTHOR]

Published
2024
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27. Development of an Earth-Field Nuclear Magnetic Resonance Spectrometer: Paving the Way for AI-Enhanced Low-Field Nuclear Magnetic Resonance Technology.

Author

Viciana, Eduardo, Martínez-Lao, Juan Antonio, López-Lao, Emilio, Fernández, Ignacio, and Arrabal-Campos, Francisco Manuel

Subjects
NMR spectrometers, GEOMAGNETISM, NUCLEAR magnetic resonance, MAGNETIC fields, SPIN excitations
Abstract

Today, it is difficult to have a high-field nuclear magnetic resonance (NMR) device due to the high cost of its acquisition and maintenance. These high-end machines require significant space and specialist personnel for operation and offer exceptional quality in the acquisition, processing, and other advanced functions associated with detected signals. However, alternative devices are low-field nuclear magnetic resonance devices. They benefit from the elimination of high-tech components that generate static magnetic fields and advanced instruments. Instead, they used magnetic fields induced by ordinary conductors. Another category of spectrometers uses the Earth's magnetic field, which is simple and economical but limited in use. These devices are called Earth-Field Nuclear Magnetic Resonance (EFNMR) devices. This device is ideal for educational purposes, especially for engineers and those who study nuclear magnetic resonance, such as chemistry or other experimental sciences. Students can observe their internal workings and conduct experiments that complement their education without worrying about damaging equipment. This article provides a detailed explanation of the design and construction of electrical technology devices for the excitation of atomic spin resonance using Earth's magnetic fields. It covers all necessary stages, from research to analysis, including simulation, assembly, construction of each component, and the development of comprehensive software for spectrometer control. [ABSTRACT FROM AUTHOR]

Published
2024
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29. Cardiac Rehabilitation Increases Plasma Klotho Levels

Author

Pello Lázaro, Ana María, primary, Villelabeitia Jaureguizar, Koldo, additional, Franco Peláez, Juan Antonio, additional, Venegas-Rodriguez, Ana, additional, Aceña, Álvaro, additional, Kallmeyer, Andrea, additional, Cánovas, Ester, additional, González-Casaus, María Luisa, additional, Tarín, Nieves, additional, Cristóbal, Carmen, additional, Gutiérrez-Landaluce, Carlos, additional, Huelmos, Ana, additional, González-Lorenzo, Óscar, additional, Alonso, Joaquín, additional, López-Bescós, Lorenzo, additional, Egido, Jesús, additional, Mahillo-Fernández, Ignacio, additional, Lumpuy-Castillo, Jairo, additional, Lorenzo, Óscar, additional, and Tuñón, José, additional

Published
2024
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32. The Direct Effects of Climate Change on Tench (Tinca tinca) Sperm Quality under a Real Heatwave Event Scenario

Author

Ministerio de Ciencia e Innovación (España), Agencia Estatal de Investigación (España), European Commission, Fernández, Ignacio, Larrán, Ana M., de Paz, Paulino, Riesco, Marta F., Ministerio de Ciencia e Innovación (España), Agencia Estatal de Investigación (España), European Commission, Fernández, Ignacio, Larrán, Ana M., de Paz, Paulino, and Riesco, Marta F.

Abstract

Global aquaculture growth will most probably face specific conditions derived from climate change. In fact, the most severe impacts of these changes will be suffered by aquatic populations in restrictive circumstances, such as current aquaculture locations, which represent a perfect model to study global warming effects. Although the impact of temperature on fish reproduction has been characterized in many aspects, this study was focused on recreating more realistic models of global warming, particularly considering heatwave phenomena, in order to decipher its effects on male gametes (spermatozoa). For this purpose, thermal stress via a heatwave simulation (mimicking a natural occurring heatwave, from 24 to 30 °C) was induced in adult tench (Tinca tinca) males and compared with a control group (55.02 ± 16.44 g of average body wet weight). The impact of the thermal stress induced by this climate change event was assessed using cellular and molecular approaches. After the heatwave recreation, a multiparametric analysis of sperm quality, including some traditional parameters (such as sperm motility) and new ones (focus on redox balance and sperm quality biomarkers), was performed. Although sperm concentration and the volume produced were not affected, the results showed a significant deleterious effect on motility parameters (e.g., reduced progressive motility and total motility during the first minute post-activation). Furthermore, the sperm produced under the thermal stress induced by this heatwave simulation exhibited an increased ROS content in spermatic cells, confirming the negative effect that this thermal stress model (heatwave recreation) might have had on sperm quality. More importantly, the expression of some known sperm quality and fertilization markers was decreased in males exposed to thermal stress. This present study not only unveils the potential effects of climate change in contemporary and future fish farming populations (and their underlying

Published
2024

33. The decarbonisation of the maritime sector: Horizon 2050

Author

Mahía Prados, José Miguel, Arias Fernández, Ignacio, Romero Gómez, Manuel, Naveiro Parga, Manuel, Mahía Prados, José Miguel, Arias Fernández, Ignacio, Romero Gómez, Manuel, and Naveiro Parga, Manuel

Abstract

The decarbonisation of the maritime sector is one of the world's priorities to reduce the volume of polluting emissions. The basis of this decarbonisation is the adaptation of existing ships to emission control regulations by means of transformations, installation of new equipment, development of new low-emission fuels and development of the infrastructure that makes the supply of this new generation of fuels feasible. In addition, hydrogen is the energy vector for all these new technologies, and its role over the next 30 years needs to be addressed. In a changing global situation such as the one we are currently experiencing; this article has the objective of making a review paper on the different fuels currently being used in the maritime sector and the existing alternatives. It also discusses the situation and the impact the current environmental situation has on the world ship order book, both in terms of legislation and economics. As a conclusion, the Liquefied Natural Gas (LNG) will have a very important role to play as a bridge between the current situation and the development of hydrogen technology. Hydrogen is an energy vector that can achieve the decarbonisation objectives by 2050. Storage problems, lack of infrastructures to supply it and the development of technology and regulations are the major challenges it will have to face. Biofuels also present a serious proposal for the decarbonisation of the sector, and the role of hydrogen in their composition, is essential to achieve green fuel generation.

Published
2024

34. Interaction of angiotensin II with the angiotensin type 2 receptor inhibits the cardiac transient outward potassium current

Author

Caballero Collado, Ricardo, Gómez García, Ricardo, Moreno, Fernández, Ignacio, Núñez Fernández, Lucía, González, Teresa, Arias, Cristina, Guizy, Miriam, Valenzuela, Carmen, Tamargo Menéndez, Juan, Delpón Mosquera, María Eva, Caballero Collado, Ricardo, Gómez García, Ricardo, Moreno, Fernández, Ignacio, Núñez Fernández, Lucía, González, Teresa, Arias, Cristina, Guizy, Miriam, Valenzuela, Carmen, Tamargo Menéndez, Juan, and Delpón Mosquera, María Eva

Abstract

Objective: The Ca2+ -independent transient outward K+ current (Ito) plays a crucial role in shaping the cardiac action potential. In the present study, we examined whether angiotensin II (AngII) regulated the Ito as well as the putative intracellular cascade responsible for the effects. Methods: Ito was recorded in rat ventricular myocytes using the nystatin-perforated patch-clamp configuration. Results: AngII (0.1 microM) inhibited Ito (21.9+/-4.8% at +40 mV), but not the IK1, in a voltage- and time-independent manner. The inhibition decreased at concentrations higher than 1 microM resulting in a bell-shaped dose-response curve (IC50 = 3.1+/-1.5 microM). The blocking effects were abolished in the presence of the type 2 AngII receptor (AT2R) antagonist PD123319, but not in the presence of the selective type 1 AngII receptor (AT1R) antagonist candesartan. Moreover, the selective AT2R agonist CGP42112A completely reproduced the effects of AngII (20.5+/-2.4% of block at +40 mV), indicating that AngII-induced Ito block was mediated via stimulation of AT2R. Furthermore, selective stimulation of AT2R by CGP42112A significantly prolonged the rat atrial action potentials recorded using conventional microelectrode techniques. The AngII-induced inhibition of I(to) was not modified by either Npi-nitro-L-arginine-methyl ester (L-NAME) or eicosatetrayonic acid (ETYA), indicating that neither the nitric oxide (NO)-guanosine 3',5'-cyclic monophosphate (cGMP) system nor the arachidonic acid cascade was implicated in the effects of AngII on Ito. However, the AngII-induced Ito inhibition was completely abolished by the serine/threonine phosphatase type 2A (PP2A) inhibitors, okadaic acid and cantharidin, but not by the inactive analog of okadaic acid, 1-norokadaone. Intracellular application of PP2A decreased Kv4.2 currents recorded in transiently transfected Chinese hamster ovary cells (CHO). Conclusion: These results indicate that AngII activates PP2A through the stimulation of the, Comisión Interministerial de Ciencia y Tecnología, Comunidad de Madrid, Instituto de Salud Carlos III, Pfizer Foundation, Depto. de Farmacología y Toxicología, Fac. de Medicina, TRUE, pub

Published
2024

35. The decarbonisation of the maritime sector: Horizon 2050

Author

Romero Gómez, Manuel, Naveiro, Manuel, Arias-Fernández, Ignacio, Mahía Prados, José Miguel, Romero Gómez, Manuel, Naveiro, Manuel, Arias-Fernández, Ignacio, and Mahía Prados, José Miguel

Abstract

[Abstract] The decarbonisation of the maritime sector is one of the world's priorities to reduce the volume of polluting emissions. The basis of this decarbonisation is the adaptation of existing ships to emission control regulations by means of transformations, installation of new equipment, development of new low-emission fuels and development of the infrastructure that makes the supply of this new generation of fuels feasible. In addition, hydrogen is the energy vector for all these new technologies, and its role over the next 30 years needs to be addressed. In a changing global situation such as the one we are currently experiencing; this article has the objective of making a review paper on the different fuels currently being used in the maritime sector and the existing alternatives. It also discusses the situation and the impact the current environmental situation has on the world ship order book, both in terms of legislation and economics. As a conclusion, the Liquefied Natural Gas (LNG) will have a very important role to play as a bridge between the current situation and the development of hydrogen technology. Hydrogen is an energy vector that can achieve the decarbonisation objectives by 2050. Storage problems, lack of infrastructures to supply it and the development of technology and regulations are the major challenges it will have to face. Biofuels also present a serious proposal for the decarbonisation of the sector, and the role of hydrogen in their composition, is essential to achieve green fuel generation.

Published
2024

42. COMPARISON OF LONG-TERM RESPONSE AND REMISSION TO OMALIZUMAB AND ANTI-IL5/IL5R USING DIFFERENT CRITERIA IN A REAL-LIFE COHORT OF SEVERE ASTHMA PATIENTS

Author

Valverde-Monge, Marcela, primary, Sánchez-Carrasco, Patricia, additional, Betancor, Diana, additional, Barroso, Blanca, additional, Manuel Rodrigo-Muñoz, José, additional, Mahillo-Fernández, Ignacio, additional, Arismendi, Ebymar, additional, Bobolea, Irina, additional, Cárdaba, Blanca, additional, Cruz, María Jesús, additional, Pozo, Victoria Del, additional, Domínguez-Ortega, Javier, additional, González-Barcala, Francisco Javier, additional, María Olaguibel, José, additional, Luna-Porta, JA, additional, Martínez-Rivera, Carlos, additional, Mullol, Joaquim, additional, Muñoz, Xavier, additional, Peleteiro-Pedraza, Lorena, additional, Valles, Cesar Picado, additional, Plaza, Vicente, additional, Quirce, Santiago, additional, Rial, Manuel Jorge, additional, Soto-Retes, Lorena, additional, Valero, Antonio, additional, and Sastre, Joaquín, additional

Published
2023
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43. Generation of H2 on Board Lng Vessels for Consumption in the Propulsion System

Author

Fernández Ignacio Arias, Gómez Manuel Romero, Gómez Javier Romero, and López-González Luis M.

Subjects
boil-off gas, efficiency, h2 storage, lng vessel, reforming, Naval architecture. Shipbuilding. Marine engineering, VM1-989
Abstract

At present, LNG vessels without reliquefaction plants consume the BOG (boil-off gas) in their engines and the excess is burned in the gas combustion unit without recovering any of its energy content. Excess BOG energy could be captured to produce H2, a fuel with high energy density and zero emissions, through the installation of a reforming plant. Such H2 production would, in turn, require on-board storage for its subsequent consumption in the propulsion plant when navigating in areas with stringent anti-pollution regulations, thus reducing CO2 and SOX emissions. This paper presents a review of the different H2 storage systems and the methods of burning it in propulsion engines, to demonstrate the energetic viability thereof on board LNG vessels. Following the analysis, it is identified that a pressurised and cooled H2 storage system is the best suited to an LNG vessel due to its simplicity and the fact that it does not pose a safety hazard. There are a number of methods for consuming the H2 generated in the DF engines that comprise the propulsion plant, but the use of a mixture of 70% CH4-30% H2 is the most suitable as it does not require any modifications to the injection system. Installation of an on-board reforming plant and H2 storage system generates sufficient H2 to allow for almost 3 days’ autonomy with a mixture of 70%CH4-30%H2. This reduces the engine consumption of CH4 by 11.38%, thus demonstrating that the system is not only energy-efficient, but lends greater versatility to the vessel.

Published
2020
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47. Red Vetchling (Lathyrus cicera L.), a Promising Crop for the Sustainable Replacement of Soybean Meal and Reducing the Carbon Footprint of European Aquafeeds

Author

Toledo-Solís, Francisco Javier, primary, Mokhles Abadi Farahani, Amin, additional, Yagüe, Sara, additional, Mateos-Aparicio, Inmaculada, additional, Pérez, Valentín, additional, Larrán, Ana María, additional, Moyano, Francisco Javier, additional, and Fernández, Ignacio, additional

Published
2023
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49. La evolución de los escenarios del consumo urbano. El caso de la calle San Andrés en la ciudad de A Coruña

Author

Samuel Fernández Ignacio

Subjects
historia urbana, marketing urbano, consumo, iconografía, identidad, identidade, History of Spain, DP1-402
Abstract

En este trabajo de investigación se exploran los escenarios de la ciudad contemporánea atendiendo a la relación que existe entre las identidades urbanas y los elementos de iconografía más representativos de esos lugares. La identidad social que asumen los individuos se genera en la dinámica de la compleja trama de interacciones que se desarrolla dentro de un contexto cultural determinado. Desde la aparición del urbanismo decimonónico, las ciudades modernas se han reconfigurado según las necesidades espaciales derivadas de las actividades económicas que la burguesía industrial y comercial ha liderado. La evolución de los mercados internacionales, la deslocalización de gran parte de la industria y la lógica cultural inserta en la producción de mercancías en las sociedades del capitalismo avanzado han impulsado el fenómeno global de las marcas corporativas. Compitiendo entre ellas por atraer a inversores, ciudadanos y turistas, las ciudades, convertidas en mercancías, han rediseñado sus identidades recurriendo al fetiche de la marca. [gl] Neste traballo de investigación explóranse os escenarios da cidade contemporánea atendendo á relación que existe entre as identidades urbanas e os elementos de iconografía máis representativos deses lugares. A identidade social que asumen os individuos xérase na dinámica da complexa trama de interaccións que se desenvolve dentro dun contexto cultural determinado. Desde a aparición do urbanismo decimonónico, as cidades modernas reconfiguráronse segundo as necesidades espaciais derivadas das actividades económicas que a burguesía industrial e comercial ten liderado. A evolución dos mercados internacionais, a deslocalización da meirande parte da industria e a lóxica cultural inserida na produción de mercadorías nas sociedades do capitalismo avanzado impulsou o fenómeno global das marcas corporativas. Competindo entre si por atraer investidores, cidadáns e turistas, as cidades, agora convertidas en mercadorías, redeseñaron as súas identidades recorrendo ao fetiche da marca.

Published
2018
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50. Urbanismo de marca y lugares de culto. Reflexiones a partir de un viaje a Lisboa

Author

Samuel Fernández Ignacio

Subjects
marketing urbano, disneyficación, religión, Sociology (General), HM401-1281
Abstract

El marketing ha reducido a mercancía el mundo religioso. Por otro lado, los discursos publicitarios han difundido una ideología que sacraliza el rol que juegan los productos dentro de las prácticas rituales de la vida cotidiana. Las mercancías culturales permiten a los individuos distinguirse en sus elecciones de consumo, confeccionando un corpus de creencias y valores que configuran formas alternativas de experimentar lo religioso al margen de las iglesias. El presente artículo explora las posibles semejanzas que se pueden dar entre : 1) las lógicas que guían la producción simbólica de los escenarios urbanos del capitalismo avanzado y 2) las que habitualmente se relacionan con la experiencia de lo sagrado.

Published
2018
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