1. Pneumococcal vaccination in celiac disease
- Author
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Fabio Ingravalle, Giorgio Abbate, Gabrio Bassotti, Antonio Carroccio, Fulvio Bonetti, Pasquale Mansueto, Giovanni Casella, Vincenzo Villanacci, Claudio Monti, and Casella G, Ingravalle F, Abbate G, Monti C, Bonetti F, Bassotti G, Mansueto P, Villanacci V, Carroccio A.
- Subjects
Settore MED/09 - Medicina Interna ,Disease ,Opportunistic Infections ,Hypersplenism ,Pneumococcal Infections ,Pneumococcal Vaccines ,Immunocompromised Host ,03 medical and health sciences ,0302 clinical medicine ,Risk Factors ,hyposplenism ,Animals ,Humans ,Celiac disease ,pneumonia ,Medicine ,infections ,chemistry.chemical_classification ,Hepatology ,business.industry ,Vaccination ,Gastroenterology ,nutritional and metabolic diseases ,pneumococcal vaccination ,Protective Factors ,Prognosis ,Gluten ,infection ,digestive system diseases ,chemistry ,Infectious disease (medical specialty) ,030220 oncology & carcinogenesis ,Pneumococcal vaccination ,Immunology ,030211 gastroenterology & hepatology ,business ,Spleen - Abstract
Introduction: Celiac disease (CD) is an immune-mediated disorder associated with gluten exposure in genetically predisposed subjects. Areas covered: Infectious disease is one of the causes of morbidity and mortality in CD patients. Invasive streptococcus pneumoniae (pneumococcus) is a particularly dangerous morbid condition in both the general population and celiac patients. Pneumococcal vaccination is the most effective means for its prevention. Expert opinion: In CD, evaluation of spleen function should be useful to select patients who may benefit from vaccination to reduce the risk of pneumococcal disease. Different strategies could be employed: physicians could search for signs of hyposplenism on peripheral blood smear or abdominal ultrasound. However, the best strategy to identify which patients will benefit from pneumococcal vaccination has not yet been defined.
- Published
- 2019