Search

Your search keyword '"Gustin, J."' showing total 118 results
Start Over Author "Gustin, J." Search Limiters Available in Library Collection
118 results on '"Gustin, J."'

1. The EChO science case

Author

Tinetti, Giovanna, Drossart, Pierre, Eccleston, Paul, Hartogh, Paul, Isaak, Kate, Linder, Martin, Lovis, Christophe, Micela, Giusi, Ollivier, Marc, Puig, Ludovic, Ribas, Ignasi, Snellen, Ignas, Allard, Bruce Swinyard. France, Barstow, Joanna, Cho, James, Coustenis, Athena, Cockell, Charles, Correia, Alexandre, Decin, Leen, de Kok, Remco, Deroo, Pieter, Encrenaz, Therese, Forget, Francois, Glasse, Alistair, Griffith, Caitlin, Guillot, Tristan, Koskinen, Tommi, Lammer, Helmut, Leconte, Jeremy, Maxted, Pierre, Mueller-Wodarg, Ingo, Nelson, Richard, North, Chris, Pallé, Enric, Pagano, Isabella, Piccioni, Guseppe, Pinfield, David, Selsis, Franck, Sozzetti, Alessandro, Stixrude, Lars, Tennyson, Jonathan, Turrini, Diego, Beaulieu, Mariarosa Zapatero-Osorio. Jean-Philippe, Grodent, Denis, Guedel, Manuel, Luz, David, Nørgaard-Nielsen, Hans Ulrik, Ray, Tom, Rickman, Hans, Selig, Avri, Banaszkiewicz, Mark Swain. Marek, Barlow, Mike, Bowles, Neil, Branduardi-Raymont, Graziella, Foresto, Vincent Coudé du, Gerard, Jean-Claude, Gizon, Laurent, Hornstrup, Allan, Jarchow, Christopher, Kerschbaum, Franz, Kovacs, Géza, Lagage, Pierre-Olivier, Lim, Tanya, Lopez-Morales, Mercedes, Malaguti, Giuseppe, Pace, Emanuele, Pascale, Enzo, Vandenbussche, Bart, Wright, Gillian, Adriani, Gonzalo Ramos Zapata. Alberto, Azzollini, Ruymán, Balado, Ana, Bryson, Ian, Burston, Raymond, Colomé, Josep, Crook, Martin, Di Giorgio, Anna, Griffin, Matt, Hoogeveen, Ruud, Ottensamer, Roland, Irshad, Ranah, Middleton, Kevin, Morgante, Gianluca, Pinsard, Frederic, Rataj, Mirek, Reess, Jean-Michel, Savini, Giorgio, Schrader, Jan-Rutger, Stamper, Richard, Abe, Berend Winter. L., Abreu, M., Achilleos, N., Ade, P., Adybekian, V., Affer, L., Agnor, C., Agundez, M., Alard, C., Alcala, J., Prieto, C. Allende, Floriano, F. J. Alonso, Altieri, F., Iglesias, C. A. Alvarez, Amado, P., Andersen, A., Aylward, A., Baffa, C., Bakos, G., Ballerini, P., Banaszkiewicz, M., Barber, R. J., Barrado, D., Barton, E. J., Batista, V., Bellucci, G., Avilés, J. A. Belmonte, Berry, D., Bézard, B., Biondi, D., Błęcka, M., Boisse, I., Bonfond, B., Bordé, P., Börner, P., Bouy, H., Brown, L., Buchhave, L., Budaj, J., Bulgarelli, A., Burleigh, M., Cabral, A., Capria, M. T., Cassan, A., Cavarroc, C., Cecchi-Pestellini, C., Cerulli, R., Chadney, J., Chamberlain, S., Charnoz, S., Jessen, N. Christian, Ciaravella, A., Claret, A., Claudi, R., Coates, A., Cole, R., Collura, A., Cordier, D., Covino, E., Danielski, C., Damasso, M., Deeg, H. J., Delgado-Mena, E., Del Vecchio, C., Demangeon, O., De Sio, A., De Wit, J., Dobrijévic, M., Doel, P., Dominic, C., Dorfi, E., Eales, S., Eiroa, C., Contreras, M. Espinoza, Esposito, M., Eymet, V., Fabrizio, N., Fernández, M., Castella, B. Femenía, Figueira, P., Filacchione, G., Fletcher, L., Focardi, M., Fossey, S., Fouqué, P., Frith, J., Galand, M., Gambicorti, L., Gaulme, P., López, R. J. García, Garcia-Piquer, A., Gear, W., Gerard, J. -C., Gesa, L., Giani, E., Gianotti, F., Gillon, M., Giro, E., Giuranna, M., Gomez, H., Gomez-Leal, I., Hernandez, J. Gonzalez, Merino, B. González, Graczyk, R., Grassi, D., Guardia, J., Guio, P., Gustin, J., Hargrave, P., Haigh, J., Hébrard, E., Heiter, U., Heredero, R. L., Herrero, E., Hersant, F., Heyrovsky, D., Hollis, M., Hubert, B., Hueso, R., Israelian, G., Iro, N., Irwin, P., Jacquemoud, S., Jones, G., Jones, H., Justtanont, K., Kehoe, T., Kerschbaum, F., Kerins, E., Kervella, P., Kipping, D., Koskinen, T., Krupp, N., Lahav, O., Laken, B., Lanza, N., Lellouch, E., Leto, G., Goldaracena, J. Licandro, Lithgow-Bertelloni, C., Liu, S. J., Cicero, U. Lo, Lodieu, N., Lognonné, P., Lopez-Puertas, M., Lopez-Valverde, M. A., Rasmussen, I. Lundgaard, Luntzer, A., Machado, P., MacTavish, C., Maggio, A., Maillard, J. -P., Magnes, W., Maldonado, J., Mall, U., Marquette, J. -B., Mauskopf, P., Massi, F., Maurin, A. -S., Medvedev, A., Michaut, C., Miles-Paez, P., Montalto, M., Rodríguez, P. Montañés, Monteiro, M., Montes, D., Morais, H., Morales, J. C., Morales-Calderón, M., Morello, G., Martín, A. Moro, Moses, J., Bedon, A. Moya, Alcaino, F. Murgas, Oliva, E., Orton, G., Palla, F., Pancrazzi, M., Pantin, E., Parmentier, V., Parviainen, H., Ramírez, K. Y. Peña, Peralta, J., Perez-Hoyos, S., Petrov, R., Pezzuto, S., Pietrzak, R., Pilat-Lohinger, E., Piskunov, N., Prinja, R., Prisinzano, L., Polichtchouk, I., Poretti, E., Radioti, A., Ramos, A. A., Rank-Lüftinger, T., Read, P., Readorn, K., López, R. Rebolo, Rebordão, J., Rengel, M., Rezac, L., Rocchetto, M., Rodler, F., Béjar, V. J. Sánchez, Lavega, A. Sanchez, Sanromá, E., Santos, N., Forcada, J. Sanz, Scandariato, G., Schmider, F. -X., Scholz, A., Scuderi, S., Sethenadh, J., Shore, S., Showman, A., Sicardy, B., Sitek, P., Smith, A., Soret, L., Sousa, S., Stiepen, A., Stolarski, M., Strazzulla, G., Tabernero, H. M, Tanga, P., Tecsa, M., Temple, J., Terenzi, L., Tessenyi, M., Testi, L., Thompson, S., Thrastarson, H., Tingley, B. W., Trifoglio, M., Torres, J. Martín, Tozzi, A., Turrini, D., Varley, R., Vakili, F., de Val-Borro, M., Valdivieso, M. L., Venot, O., Villaver, E., Vinatier, S., Viti, S., Waldmann, I., Waltham, D., Ward-Thompson, D., Waters, R., Watkins, C., Watson, D., Wawer, P., Wawrzaszk, A., White, G., Widemann, T., Winek, W., Wiśniowski, T., Yelle, R., Yung, Y., and Yurchenko, S. N.

Subjects
Astrophysics - Earth and Planetary Astrophysics
Abstract

The discovery of almost 2000 exoplanets has revealed an unexpectedly diverse planet population. Observations to date have shown that our Solar System is certainly not representative of the general population of planets in our Milky Way. The key science questions that urgently need addressing are therefore: What are exoplanets made of? Why are planets as they are? What causes the exceptional diversity observed as compared to the Solar System? EChO (Exoplanet Characterisation Observatory) has been designed as a dedicated survey mission for transit and eclipse spectroscopy capable of observing a large and diverse planet sample within its four-year mission lifetime. EChO can target the atmospheres of super-Earths, Neptune-like, and Jupiter-like planets, in the very hot to temperate zones (planet temperatures of 300K-3000K) of F to M-type host stars. Over the next ten years, several new ground- and space-based transit surveys will come on-line (e.g. NGTS, CHEOPS, TESS, PLATO), which will specifically focus on finding bright, nearby systems. The current rapid rate of discovery would allow the target list to be further optimised in the years prior to EChO's launch and enable the atmospheric characterisation of hundreds of planets. Placing the satellite at L2 provides a cold and stable thermal environment, as well as a large field of regard to allow efficient time-critical observation of targets randomly distributed over the sky. A 1m class telescope is sufficiently large to achieve the necessary spectro-photometric precision. The spectral coverage (0.5-11 micron, goal 16 micron) and SNR to be achieved by EChO, thanks to its high stability and dedicated design, would enable a very accurate measurement of the atmospheric composition and structure of hundreds of exoplanets., Comment: 50 pages, 30 figures. Experimental Astronomy

Published
2015
Full Text
View/download PDF

2. Multi-spectral simultaneous diagnosis of Saturns aurorae throughout a planetary rotation

Author

Lamy, L., Prangé, R., Pryor, W., Gustin, J., Badman, S. V., Melin, H., Stallard, T., Mitchell, D. G., and Brandt, P. C.

Subjects
Astrophysics - Earth and Planetary Astrophysics
Abstract

From the 27th to the 28th January 2009, the Cassini spacecraft remotely acquired combined observations of Saturns southern aurorae at radio, ultraviolet and infrared wavelengths, while monitoring ion injections in the middle magnetosphere from energetic neutral atoms. Simultaneous measurements included the sampling of a full planetary rotation, a relevant timescale to investigate auroral emissions driven by processes internal to the magnetosphere. In addition, this interval coincidently matched a powerful substorm-like event in the magnetotail, which induced an overall dawnside intensification of the magnetospheric and auroral activity. We comparatively analyze this unique set of measurements to reach a comprehensive view of kronian auroral processes over the investigated timescale. We identify three source regions in atmospheric aurorae, including a main oval associated with the bulk of Saturn Kilometric Radiation (SKR), together with polar and equatorward emissions. These observations reveal the co-existence of corotational and sub-corototational dynamics of emissions associated with the main auroral oval. Precisely, we show that the atmospheric main oval hosts short-lived sub-corotating isolated features together with a bright, longitudinally extended, corotating region locked at the southern SKR phase. We assign the susbtorm-like event to a regular, internally driven, nightside ion injection possibly triggerred by a plasmoid ejection. We also investigate the total auroral energy budget, from the power input to the atmosphere, characterized by precipitating electrons up to 20 keV, to its dissipation through the various radiating processes. Finally, through simulations, we confirm the search-light nature of the SKR rotational modulation and we show that SKR arcs relate to isolated auroral spots. The resulting findings are discussed in the frame of pending questions.

Published
2013
Full Text
View/download PDF

4. COVID-19 Diagnostic Testing For All - Using Non-Dilutive Saliva Sample Collection, Stabilization and Ambient Transport Devices

Author

Rezaei M, Aiyer Ra, Nasarabadi S, Greene E, Gustin J, Romero A, Orlino J, Carrington Y, and Rose S

Subjects
Saliva, Coronavirus disease 2019 (COVID-19), business.industry, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Transport medium, Process efficiency, Diagnostic test, Medicine, Sample collection, Food science, Saliva sample, business, Article
Abstract

COVID-19 testing is not accessible for millions during this pandemic despite our best efforts. Without greatly expanded testing of asymptomatic individuals, contact tracing and subsequent isolation of spreaders remains as a means for control. In an effort to increase RT-PCR assay testing for the presence of the novel beta-coronavirus SARS-CoV-2 as well as improve sample collection safety, GenTegra LLC has introduced two products for saliva collection and viral RNA stabilization: GTR-STM™ (GenTegra Saliva Transport Medium) and GTR-STMdk™ (GenTegra Saliva Transport Medium Direct to PCR). Both products contain a proprietary formulation based on GenTegra’s novel “Active Chemical Protection™” (ACP) technology that gives non-dilutive, error-free saliva sample collection using RNA stabilization chemicals already dried in the collection tube.GTR-STM can be used for safer saliva-based sample collection at home (or at a test site). Following saliva collection, the sample-containing GTR-STM can be kept at ambient temperature during shipment to an authorized CLIA lab for analysis. SARS-CoV-2 viral RNA in GTR-STM is stable for over a month at ambient temperature, easily surviving the longest transit times from home to lab. GTR-STM enhances patient comfort, convenience, compliance and reduces infectious virus exposure to essential medical and lab professionals.Alternatively, the GTR-STMdk direct-into-PCR product can be used to improve lab throughput and reduce reagent costs for saliva sample collection and testing at any lab site with access to refrigeration. GTR-STMdk reduces lab process time by 25% and reagent costs by 30% compared to other approaches. Since GTR-STMdk retains SARS-CoV-2 viral RNA stability for three days at ambient temperature, it is optimized for lab test site rather than at home saliva collection. SARS-COV-2 viral RNA levels as low as 0.4 genome equivalents/uL are detected in saliva samples using GTR-STMdk. The increased sensitivity of SARS-CoV-2 detection can expand COVID-19 testing to include asymptomatic individuals using pooled saliva.One Sentence SummaryGTR-STM and Direct-into-PCR GTR-STMdk offer substantive improvements in SARS-CoV-2 viral RNA stability, safety, and RT-PCR process efficiency for COVID-19 testing by using a non-dilutive saliva sample collection system for individuals at home or onsite respectively.

Published
2021

10. The EChO science case

Author

Tinetti, G., Drossart, P., Eccleston, P., Hartogh, P., Isaak, K., Linder, M., Lovis, C., Micela, G., Olliver, M., Puig, L., Ribas, I., De Sio, A., Frith, J., Justtanot, K., Showman, A., Alard, C., Yurchenko, S. N., Parviainen, H., Fouqué, P., Oliva, E., Bordé, P., Balado, A., Varley, R., Di Giorgio, A., Griffin, M., Maillard, J. P., Maggio, A., Lellouch, E., Strazzulla, G., Villaver, E., Griffith, C., Stamper, R., Amado, P. J., Rezac, L., Laken, B., Hargrave, P., Orton, G., Thompson, S., Morales, J. C., Wright, G., Massi, F., Lundgaard Rasmussen, I., Altieri, F., Covino, E., Coustenis, A., Moses, J., Lithgow Bertelloni, C., Demangeon, O., Fletcher, L., Morales Calderón, M., Lo Cicero, U., López Puertas, M., Capria, M. T., Danielski, C., Luntzer, A., Bulgarelli, A., González Hernández, J., Jacquemoud, S., MacTavish, C., Mall, U., Christian Jessen, N., Sanromá, E., Femenía Castella, B., Rocchetto, M., Miles Paez, P., Allard, F., Aylward, A., Leconte, J., Palla, F., White, G., Malaguti, G., Cavarroc, C., Lammer, H., Leto, G., Batista, V., Adybekian, V., Readorn, K., Polichtchouk, I., Petrov, R., García Piquer, A., Pancrazzi, M., Gómez Leal, I., Israelian, G., Rebolo López, R., Peralta, J., Giro, E., Tecsa, M., Haigh, J., Moro Martín, A., Pezzuto, S., Piskunov, N., Agnor, C., Hollis, M., Radioti, A., De Kok, R., Gear, W., Eymet, V., Achilleos, N., Koskinen, T., Maurin, A. S., Rank Lüftinger, T., Barlow, M., Figueira, P., Affer, L., Viti, S., Machado, P., Vakili, F., Burston, R., González Merino, B., Dominic, C., Dorfi, E., Smith, A., Sitek, P., Sánchez Lavega, A., Kerschbaum, F., Hoogeeven, R., Ballerini, P., Filacchione, G., Rodler, F., Stixrude, L., Parmentier, V., Del Val Borro, M., Vandenbussche, B., Tingley, B. W., Deeg, H. J., Tabernero, H. M., Shore, S., Fossey, S., Alonso Floriano, F. J., Santos, N., Tozzi, A., Kipping, D., Maruquette, J. B., Trifoglio, M., Scandaratio, G., Scuderi, S., Hébrard, E., Lodieu, N., Forget, F., Gustin, J., Poretti, E., Murgas Alcaino, F., Sicardy, B., Stiepen, A., Hubert, B., Grodent, D., Magnes, W., Tennyson, J., Temple, J., Galand, M., Barton, E. J., Winter, B., Valdivieso, M. L., Cordier, D., Heredero, R. L., Barrado, D., Mueller Wodarg, I., Giani, E., Correira, A., Widemann, T., Ward Thompson, D., Montañés Rodríguez, P., Moya Bedon, A., Venot, O., Prinja, R., Pinfield, D., Waldmann, I., Morello, G., Lim, T., Pallé, E., Waters, R., Wawer, P., Lognonné, P., Pietrzak, R., Fernández Hernández, Maite, Winek, W., Andersen, A., Monteiro, M., Liu, S. J., Rengel, M., Tanga, P., Yelle, R., Barstow, J. K., Maldonado, J., Irshad, R., Nelson, R., Colomé, J., De Witt, J., Lanza, N., Glasse, A., Coudé du Foresto, V., Branduardi Raymont, G., Beaulieu, J. P., Claudi, R., García López, Ramón, Eales, S., López Valverde, M. A., Turrini, D., Vinatier, S., Crook, J., Damasso, M., Ramos Zapata, G., Kovács, G., Banaszkiewicz, M., Focardi, M., Mauskopf, P., Guedel, M., Rebordao, J., Stolarski, M., Adriani, A., Norgaard Nielsen, H. U., Selig, A., Peña Ramírez, K. Y., Schmider, F. X., Baffa, C., Piccioni, G., Pantin, E., Bowles, N., Hornstrup, A., Pilat Lohinger, E., Buchhave, L. A., Soret, L., Börne, P., López Morales, M., Medvedev, A., Gesa, L., Jones, H., Pérez Hoyos, S., Gerard, J. C., Bellucci, G., Morais, H., Álvarez Iglesias, C. A., Abe, L., Pinsard, F., Tessenyi, M., Blecka, M., Wawrzaszk, A., Middleton, K., Martín Torres, J., Cho, J., Berry, D., Rataj, M., Schrader, J. R., Scholz, A., Watkins, C., Abreu, M., Testi, L., Decin, L., Sánz Forcada, J., Sozzetti, A., Lagage, P. O., Ade, P., Alcala, J., Sousa, S., Espinoza Contreras, M., Swinyard, B., Dobrijévic, M., Sánchez Béjar, V. J., Krupp, N., Bakos, G., Chamberlain, S., Chadney, J., Brown, L., Iro, N., Montalto, M., Sethenadh, J., Bouy, H., Ottensamer, R., Kehoe, T., Doel, P., Delgado Mena, E., Read, P., Coates, A., Cecchi Pestellini, C., Guillot, T., Budaj, J., Selsis, F., Jarchow, C., Del Vecchio, C., Cassan, A., Burleigh, M. R., Pagano, I., Ray, T., Gambicorti, L., Biondi, D., Cerulli, R., Ciaravella, A., Watson, D., Deroo, P., Collura, A., Graczyk, R., North, C., Ramos, A. A., Waltham, D., Montes, D., Gianotti, F., Thrastarson, H., Cockell, C., Pace, E., Bryson, I., Gómez, H., Esposito, M., Azzollini, R., Allende Prieto, C., Gillon, M., Fabrizio, N., Rickman, H., Rees, J. M., Pascale, E., Luzzi, D., Bonford, B., Cole, R., Gizon, L., Licandro Goldaracena, J., Agundez, M., Lahav, O., Zapatero Osorio, M. R., Gaulme, P., Encrenaz, T., Heyrovsky, D., Guàrdia, J., Prisinzano, L., Terenzi, L., Swain, M., Grassi, D., Eiroa, C., Maxted, P., Kerins, E., Yung, Y., Irwin, P., Herrero, E., Guio, P., Boisse, I., Claret, A., Kervella, P., Heiter, U., Bézard, B., Cabral, A., Michaut, C., Giuranna, M., Hersant, F., Hueso, R., Savini, G., Snellen, I. A., Charnoz, S., Jones, G., Belmonte Avilés, J. A., Barber, R. J., Wisniowski, T., Morgante, G., University College of London [London] (UCL), Laboratoire d'études spatiales et d'instrumentation en astrophysique (LESIA), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Max-Planck-Institut für Sonnensystemforschung = Max Planck Institute for Solar System Research (MPS), Max-Planck-Gesellschaft, European Space Research and Technology Centre (ESTEC), Agence Spatiale Européenne = European Space Agency (ESA), INAF - Osservatorio Astronomico di Palermo (OAPa), Istituto Nazionale di Astrofisica (INAF), Laboratoire des technologies de la microélectronique (LTM), Université Joseph Fourier - Grenoble 1 (UJF)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS), Dpto. de Organización de Empresas, Escuela Técnica Superior de Ingeniería Industrial de Barcelona, Universitat Politècnica de Catalunya [Barcelona] (UPC), Centre de Recherche Astrophysique de Lyon (CRAL), École normale supérieure de Lyon (ENS de Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), Department of Physics and Astronomy [Leicester], University of Leicester, U.S. Army Research Laboratory [Adelphi, MD] (ARL), United States Army (U.S. Army), Royal Observatory Edinburgh (ROE), University of Edinburgh, Departamento de Fisica [Aveiro], Universidade de Aveiro, SRON Netherlands Institute for Space Research (SRON), Laboratoire de Météorologie Dynamique (UMR 8539) (LMD), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut national des sciences de l'Univers (INSU - CNRS)-École polytechnique (X)-École des Ponts ParisTech (ENPC)-Centre National de la Recherche Scientifique (CNRS)-Département des Géosciences - ENS Paris, École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL), Department of Planetary Sciences [Tucson], University of Arizona, Joseph Louis LAGRANGE (LAGRANGE), Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de la Côte d'Azur, COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS), Lunar and Planetary Laboratory [Tucson] (LPL), Space Research Institute of Austrian Academy of Sciences (IWF), Austrian Academy of Sciences (OeAW), The Samuel Roberts Noble Foundation, Center for Human-Computer Interaction (HCI), Virginia Tech [Blacksburg], Istituto di Astrofisica e Planetologia Spaziali - INAF (IAPS), Centre for Astrophysics Research [Hatfield], University of Hertfordshire [Hatfield] (UH), ECLIPSE 2015, Laboratoire d'Astrophysique de Bordeaux [Pessac] (LAB), Université de Bordeaux (UB)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université de Bordeaux (UB)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), Department of Physics and Astronomy [UCL London], Laboratoire de Physique Atmosphérique et Planétaire (LPAP), Université de Liège, Centro de Astronomia e Astrofísica da Universidade de Lisboa (CAAUL), Universidade de Lisboa = University of Lisbon (ULISBOA), Department of Physics and Astronomy [Uppsala], Uppsala University, Space Research Centre of Polish Academy of Sciences (CBK), Polska Akademia Nauk = Polish Academy of Sciences (PAN), Institute for Control Engineering of Machine Tools and Manufacturing Units (ISW), University of Stuttgart, Institute for Control Engineering of Machine Tools and Manufacturing Units (ISW), Department of Atmospheric, Oceanic and Planetary Physics [Oxford] (AOPP), University of Oxford, Mullard Space Science Laboratory (MSSL), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Institut Curie [Paris], Instituut voor Sterrenkunde [Leuven], Catholic University of Leuven - Katholieke Universiteit Leuven (KU Leuven), Centre for Behaviour and Evolution, Institute of Neuroscience, Newcastle University [Newcastle], foreign laboratories (FL), CERN [Genève], STFC Rutherford Appleton Laboratory (RAL), Science and Technology Facilities Council (STFC), Estrutura de Missão para a Extensão da Plataforma Continental, Estrutura de Missão para a Extensão para a Extensão da Plataforma Continental, Centre for Planetary Sciences [UCL/Birkbeck] (CPS), Queen Mary University of London (QMUL), Institut d'Astrophysique de Paris (IAP), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), Dark Cosmology Centre (DARK), Niels Bohr Institute [Copenhagen] (NBI), Faculty of Science [Copenhagen], University of Copenhagen = Københavns Universitet (UCPH)-University of Copenhagen = Københavns Universitet (UCPH)-Faculty of Science [Copenhagen], University of Copenhagen = Københavns Universitet (UCPH)-University of Copenhagen = Københavns Universitet (UCPH), Computational Science and Engineering Department [Daresbury] (STFC), Science & Technologie Facilities Council, Departamento de Astrofisica [Madrid], Centro de Astrobiologia [Madrid] (CAB), Instituto Nacional de Técnica Aeroespacial (INTA)-Consejo Superior de Investigaciones Científicas [Madrid] (CSIC)-Instituto Nacional de Técnica Aeroespacial (INTA)-Consejo Superior de Investigaciones Científicas [Madrid] (CSIC), Calar Alto Observatory, Centro Astronómico Hispano-Alemán, Department of Geoscience, Nelson Mandela University [Port Elizabeth], African Earth Observatory Network - Earth Stewardship Science Research Institute (AEON-ESSRI), Animal Genetics, Teagasc - The Agriculture and Food Development Authority (Teagasc), Laboratoire d'Astrophysique de Marseille (LAM), Aix Marseille Université (AMU)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS), Instituto Nacional de Técnica Aeroespacial (INTA)-Consejo Superior de Investigaciones Científicas [Madrid] (CSIC), Jet Propulsion Laboratory (JPL), NASA-California Institute of Technology (CALTECH), Instituto Nacional de Engenharia, Tecnologia e Inovacao (INETI), Université Pierre et Marie Curie - Paris 6 (UPMC), CEA- Saclay (CEA), Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Università di Salerno - Dipartimento di Matematica, Università degli Studi di Salerno = University of Salerno (UNISA), Department of Genetics, University of North Carolina [Chapel Hill] (UNC), University of North Carolina System (UNC)-University of North Carolina System (UNC)-Carolina Center for the Genome Sciences, Institut de Recerca i Tecnologia Agroalimentàries = Institute of Agrifood Research and Technology (IRTA), Univers, Transport, Interfaces, Nanostructures, Atmosphère et environnement, Molécules (UMR 6213) (UTINAM), Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Department of Molecular Medicine, Università degli Studi di Padova = University of Padua (Unipd), Institut d'astrophysique spatiale (IAS), Université Paris-Sud - Paris 11 (UP11)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Centre National d’Études Spatiales [Paris] (CNES), ASP 2015, Laboratoire d'astrodynamique, d'astrophysique et d'aéronomie de bordeaux (L3AB), Université Sciences et Technologies - Bordeaux 1 (UB)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université Sciences et Technologies - Bordeaux 1 (UB)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Observatoire aquitain des sciences de l'univers (OASU), Université Sciences et Technologies - Bordeaux 1 (UB)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Laboratoire d'Astrophysique de Bordeaux [Pessac] (LAB), Université de Bordeaux (UB)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université de Bordeaux (UB), Institute for Astronomy [Vienna], University of Vienna [Vienna], Institut de génétique et microbiologie [Orsay] (IGM), Université Paris-Sud - Paris 11 (UP11)-Centre National de la Recherche Scientifique (CNRS), Deutsches Forschungszentrum für Künstliche Intelligenz GmbH = German Research Center for Artificial Intelligence (DFKI), Consejo Nacional de Investigaciones Científicas y Técnicas [Buenos Aires] (CONICET), Centro de Astrofísica da Universidade do Porto (CAUP), Universidade do Porto = University of Porto, Dipartimento di Matematica 'Ulisse Dini', Università degli Studi di Firenze = University of Florence (UniFI), Institut Universitaire de France (IUF), Ministère de l'Education nationale, de l’Enseignement supérieur et de la Recherche (M.E.N.E.S.R.), Université de Rennes (UR), Imperial College London, Laboratoire Hippolyte Fizeau (FIZEAU), School of Physics and Astronomy [Cardiff], Cardiff University, Institut d'Astrophysique et de Géophysique [Liège], Laboratoire de l'Accélérateur Linéaire (LAL), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), University of Bradford, Instituto Universitario de Electroquimica, Universidad de Alicante, Centre de recherche en éducation de Nantes (CREN), Le Mans Université (UM)-Université de Nantes - UFR Lettres et Langages (UFRLL), Université de Nantes (UN)-Université de Nantes (UN), Departamento de Fisica Aplicada [Bilbao], Universidad del Pais Vasco / Euskal Herriko Unibertsitatea [Espagne] (UPV/EHU), NASA Goddard Space Flight Center (GSFC), Onsala Space Observatory (OSO), Chalmers University of Technology [Göteborg], Los Alamos National Laboratory (LANL), Osserv Astrofis Catania, Ist Nazl Astrofis, Centre d'Etude de l'Energie Nucléaire (SCK-CEN), Institut de Physique du Globe de Paris (IPGP (UMR_7154)), Institut national des sciences de l'Univers (INSU - CNRS)-Université de La Réunion (UR)-Institut de Physique du Globe de Paris (IPG Paris)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Instituto de Astrofísica de Andalucía (IAA), Consejo Superior de Investigaciones Científicas [Madrid] (CSIC), Consejo Super Invest Cient, Inst Astrofis Andalucia, ES-18080 Granada, Spain, Department of Rheumatology (LEIDEN - Rhumato), Leiden University Medical Center (LUMC), Universiteit Leiden-Universiteit Leiden, Department of Rheumatology (COIMBRA - Rhumato), Universidade de Coimbra [Coimbra], Centre Scientifique et Technique du Bâtiment (CSTB), INAF - Osservatorio Astrofisico di Arcetri (OAA), Université de Bordeaux (UB), Institut de Physique du Globe de Paris (IPGP), Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Université de La Réunion (UR)-Institut de Physique du Globe de Paris (IPG Paris)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de physique des gaz et des plasmas (LPGP), Pontificia Universidad Católica de Chile (UC), Department of Computer Science [Verona] (UNIVR | DI), Università degli studi di Verona = University of Verona (UNIVR), IEB-UNIVERSITY OF BARCELONA, Departamento de Física e Astronomia [Porto] (DFA/FCUP), Faculdade de Ciências da Universidade do Porto (FCUP), Universidade do Porto = University of Porto-Universidade do Porto = University of Porto, Thüringer Landessternwarte Tautenburg (TLS), Bremer Institut für Produktion und Logistik GmbH (BIBA), Universität Bremen, INAF - Osservatorio Astrofisico di Catania (OACT), Plasmon Nano-optics, Institut de Ciencies Fotoniques [Castelldefels] (ICFO), Royal Holloway [University of London] (RHUL), Hong Kong Government Environmental Protection Department, Water Policy and Science Group, National Space Agencies, Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC), Max Planck Institute for Solar System Research (MPS), European Space Agency (ESA), European Space Agency, Université Joseph Fourier - Grenoble 1 (UJF)-Commissariat à l'Énergie Atomique et aux Énergies Alternatives (CEA) - Grenoble-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA), École normale supérieure - Lyon (ENS Lyon)-Université Claude Bernard Lyon 1 (UCBL), École normale supérieure - Paris (ENS Paris)-École normale supérieure - Paris (ENS Paris), Université Nice Sophia Antipolis (... - 2019) (UNS), Université Côte d'Azur (UCA)-Université Côte d'Azur (UCA)-Observatoire de la Côte d'Azur, Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS), Samuel Roberts Noble Foundation, Inc., Universidade de Lisboa (ULISBOA), Polska Akademia Nauk (PAN), University of Oxford [Oxford], Max-Planck-Institut für Sonnensystemforschung (MPS), Institut Curie, University of Copenhagen = Københavns Universitet (KU)-University of Copenhagen = Københavns Universitet (KU)-Faculty of Science [Copenhagen], University of Copenhagen = Københavns Universitet (KU)-University of Copenhagen = Københavns Universitet (KU), Consejo Superior de Investigaciones Científicas [Spain] (CSIC)-Instituto Nacional de Técnica Aeroespacial (INTA)-Consejo Superior de Investigaciones Científicas [Spain] (CSIC)-Instituto Nacional de Técnica Aeroespacial (INTA), Nelson Mandela Metropolitan University [Port Elizabeth, South Africa], AEON-ESSRI African Earth Observatory Network — Earth Stewardship Science Research Institute, Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Aix Marseille Université (AMU)-Centre National d'Études Spatiales [Toulouse] (CNES), Consejo Superior de Investigaciones Científicas [Spain] (CSIC)-Instituto Nacional de Técnica Aeroespacial (INTA), Instituto Nacional de Engenharia, Tecnologia e Inovacco (INETI), Physiologie de la reproduction et des comportements [Nouzilly] (PRC), Centre National de la Recherche Scientifique (CNRS)-Université de Tours-Institut Français du Cheval et de l'Equitation [Saumur]-Institut National de la Recherche Agronomique (INRA), Université Francois Rabelais [Tours], Institut Français du Cheval et de l'Equitation, Università degli Studi di Salerno (UNISA), IRTA, Laboratoire d'astrophysique de l'observatoire de Besançon (LAOB), Universita degli Studi di Padova, Université Paris-Sud - Paris 11 (UP11)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), Université Sciences et Technologies - Bordeaux 1-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université Sciences et Technologies - Bordeaux 1-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Observatoire aquitain des sciences de l'univers (OASU), Université Sciences et Technologies - Bordeaux 1-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Laboratoire d'Astrophysique de Bordeaux [Pessac] (LAB), Deutsches Forschungszentrum für Künstliche Intelligenz GmbH (DFKI), Universidade do Porto [Porto], Università degli Studi di Firenze [Firenze], Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES), Université Côte d'Azur (UCA)-Université Côte d'Azur (UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de la Côte d'Azur, Department of Earth Sciences, University College London, Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut national des sciences de l'Univers (INSU - CNRS)-IPG PARIS-Université Paris Diderot - Paris 7 (UPD7)-Université de La Réunion (UR)-Centre National de la Recherche Scientifique (CNRS), Consejo Superior de Investigaciones Científicas [Spain] (CSIC), Centre interdisciplinaire de recherche, culture, éducation, formation, travail (CIRCEFT), Université Paris 8 Vincennes-Saint-Denis (UP8)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Centre National de la Recherche Scientifique (CNRS)-Université de La Réunion (UR)-Université Paris Diderot - Paris 7 (UPD7)-IPG PARIS-Institut national des sciences de l'Univers (INSU - CNRS), Station biologique, Centre National de la Recherche Scientifique (CNRS), Dipartimento di Informatica [Verona], Università degli Studi di Verona, Departamento de Física e Astronomia [Porto], UMR5116, Centre Émile Durkheim (CED), Université de Bordeaux (UB)-Centre National de la Recherche Scientifique (CNRS)-Université de Bordeaux (UB)-Centre National de la Recherche Scientifique (CNRS), Clinica Neurologica, Università degli Studi di Perugia (UNIPG), Rebordao, J. [0000-0002-7418-0345], Kerschbaum, F. [0000-0001-6320-0980], Abreu, M. [0000-0002-0716-9568], Tabernero, H. [0000-0002-8087-4298], López Puertas, M. [0000-0003-2941-7734], Jacquemoud, S. [0000-0002-1500-5256], Tennyson, J. [0000-0002-4994-5238], Focardi, M. [0000-0002-3806-4283], Leto, G. [0000-0002-0040-5011], Lodieu, N. [0000-0002-3612-8968], Tinetti, G. [0000-0001-6058-6654], Sanroma, E. [0000-0001-8859-7937], Poretti, E. [0000-0003-1200-0473], Deeg, H. [0000-0003-0047-4241], Grassi, D. [0000-0003-1653-3066], Piccioni, G. [0000-0002-7893-6808], Ribas, I. [0000-0002-6689-0312], Coates, A. [0000-0002-6185-3125], García Ramón, J. [0000-0002-8204-6832], Bouy, H. [0000-0002-7084-487X[, Lognonne, P. [0000-0002-1014-920X], Demangeon, O. [0000-0001-7918-0355], Morales, J. C. [0000-0003-0061-518X], Ray, T. [0000-0002-2110-1068], Guio, P. [0000-0002-1607-5862], Tanga, P. [0000-0002-2718-997X], Prisinzano, L. [0000-0002-8893-2210], Barstow, J. [0000-0003-3726-5419], Balado, A. [0000-0003-4268-2516], Lithgow Bertelloni, C. [0000-0003-0924-6587], Barton, E. [0000-0001-5945-9244], Delgado, M. E. [0000-0003-4434-2195], Affer, L. [0000-0001-5600-3778], Ciaravella, A. [0000-0002-3127-8078], Barrado Navascues, D. [0000-0002-5971-9242], Figueira, P. [0000-0001-8504-283X], Covino, E. [0000-0002-6187-6685], Venot, O. [0000-0003-2854-765X], Cabral, A. [0000-0002-9433-871X], Watson, D. [0000-0002-4465-8264], Morales Calderon, M. [0000-0001-9526-9499], Ward Thompson, D. [0000-0003-1140-2761], Rebolo, R. [0000-0003-3767-7085], López Valverde, M. A. [0000-0002-7989-4267], Gillon, M. [0000-0003-1462-7739], Morgante, G. [0000-0001-9234-7412], Zapatero Osorio, M. R. [0000-0001-5664-2852], Bulgarelli, A. [0000-0001-6347-0649], Pena Ramírez, K. [0000-0002-5855-401X], Galand, M. [0000-0001-5797-914X], Pancrazzi, M. [0000-0002-3789-2482], Malaguti, G. [0000-0001-9872-3378], Sánchez Lavega, A. [0000-0001-7234-7634], Waldmann, I. [0000-0002-4205-5267], Kovacs, G. [0000-0002-2365-2330], Guillot, T. [0000-0002-7188-8428], Turrini, D. [0000-0002-1923-7740], Altieri, F. [0000-0002-6338-8300], Bellucci, G. [0000-0003-0867-8679], Baffa, C. [0000-0002-4935-100X], Olivia, E. [0000-0002-9123-0412], Selsis, F. [0000-0001-9619-5356], Scuderi, Salvatore [0000-0002-8637-2109], Hersant, F. [0000-0002-2687-7500], Gear, W. [0000-0001-6789-6196], Damasso, M. [0000-0001-9984-4278], Tizzi, A. [0000-0002-6725-3825], Pinfield, D. [0000-0002-7804-4260], Kipping, D. [0000-0002-4365-7366], Maldonado, J. [0000-0002-4282-1072], Pace, E. [0000-0001-5870-1772], Burleigh, M. [0000-0003-0684-7803], Monteiro, M. [0000-0001-5644-0898], Pilat Lohinger, E. [0000-0002-5292-1923], Chadney, J. [0000-0002-5174-2114], Moro Martín, A. [0000-0001-9504-8426], Claret, A. [0000-0002-4045-8134], Gómez, H. [0000-0003-3398-0052], Maldonado, J. [0000-0002-2218-5689], Michaut, C. [0000-0002-2578-0117], Hornstrup, A. [0000-0002-3363-0936], Scholz, A. [0000-0001-8993-5053], Irwin, P. [0000-0002-6772-384X], Bezard, B. [0000-0002-5433-5661], López Heredero, R. [0000-0002-2197-8388], Sanz Forcada, J. [0000-0002-1600-7835], Danielski, C. [0000-0002-3729-2663], Sousa, S. [0000-0001-9047-2965], Medved, A. [0000-0003-2713-8977], Bakos, G. [0000-0001-7204-6727], Ade, P. [0000-0002-5127-0401], Vandenbussche, B. [0000-0002-1368-3109], Martín Torres, J. [0000-0001-6479-2236], Correira, A. [0000-0002-8946-8579], Haigh, J. [0000-0001-5504-4754], Scandariato, G. [0000-0003-2029-0626], Guedel, M. [0000-0001-9818-0588], Sánchez Bejar, V. [0000-0002-5086-4232], Rodríguez, P. [0000-0002-6855-9682], Piskunov, N. [0000-0001-5742-7767], Adibekyan, V. [0000-0002-0601-6199], Pérez Hoyos, S. [0000-0001-9797-4917], Kervella, P. [0000-0003-0626-1749], Pascale, E. [0000-0002-3242-8154], Claudi, R. [0000-0001-7707-5105], Filacchione, G. [0000-0001-9567-0055], Rickman, H. [0000-0002-9603-6619], Amado, P. J. [0000-0002-8388-6040], Maggio, A. [0000-0001-5154-6108], Agundez, M. [0000-0003-3248-3564], Montes, D. [0000-0002-7779-238X], Fletcher, L. [0000-0001-5834-9588], Stixrude, L. [0000-0003-3778-2432], Morais, M. H. [0000-0001-5333-2736], Hueso, R. [0000-0003-0169-123X], Yurchenko, S. [0000-0001-9286-9501], Rataj, M. [0000-0002-2978-9629], Pérez Hoyos, S. [0000-0002-2587-4682], Santos, N. [0000-0003-4422-2919], Peralta, J. [0000-0002-6823-1695], Budaj, J. [0000-0002-9125-7340], Barlow, M. [0000-0002-3875-1171], Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Joseph Fourier - Grenoble 1 (UJF)-Centre National de la Recherche Scientifique (CNRS), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS), Département des Géosciences - ENS Paris, École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-École des Ponts ParisTech (ENPC)-École polytechnique (X)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC), Université Côte d'Azur (UCA)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Observatoire de la Côte d'Azur, COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC), Universidade do Porto, Università degli Studi di Firenze = University of Florence [Firenze] (UNIFI), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Institut national des sciences de l'Univers (INSU - CNRS)-IPG PARIS-Université Paris Diderot - Paris 7 (UPD7)-Université de La Réunion (UR)-Centre National de la Recherche Scientifique (CNRS), University of Verona (UNIVR), Universidade do Porto-Universidade do Porto, Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS), Université de Nantes - UFR Lettres et Langages (UFRLL), Université de Nantes (UN)-Université de Nantes (UN)-Le Mans Université (UM), Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-École normale supérieure - Lyon (ENS Lyon), Instituto Nacional de Técnica Aeroespacial (INTA)-Consejo Superior de Investigaciones Científicas [Spain] (CSIC)-Instituto Nacional de Técnica Aeroespacial (INTA)-Consejo Superior de Investigaciones Científicas [Spain] (CSIC), Instituto Nacional de Técnica Aeroespacial (INTA)-Consejo Superior de Investigaciones Científicas [Spain] (CSIC), Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), École normale supérieure - Paris (ENS Paris)-École normale supérieure - Paris (ENS Paris)-Centre National de la Recherche Scientifique (CNRS)-École des Ponts ParisTech (ENPC)-École polytechnique (X)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC), COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-Observatoire de la Côte d'Azur, COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-Centre National de la Recherche Scientifique (CNRS), Institut National de la Recherche Agronomique (INRA)-Institut Français du Cheval et de l'Equitation [Saumur]-Université de Tours-Centre National de la Recherche Scientifique (CNRS), Università degli Studi di Firenze = University of Florence [Firenze], COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de la Côte d'Azur, University College of London [London] ( UCL ), Laboratoire d'études spatiales et d'instrumentation en astrophysique ( LESIA ), Université Pierre et Marie Curie - Paris 6 ( UPMC ) -Institut national des sciences de l'Univers ( INSU - CNRS ) -Observatoire de Paris-Université Paris Diderot - Paris 7 ( UPD7 ) -Centre National de la Recherche Scientifique ( CNRS ), Max Planck Institute for Solar System Research ( MPS ), School of Physics & Astronomy, European Space Agency ( ESA ), INAF - Osservatorio Astronomico di Palermo ( OAPa ), Istituto Nazionale di Astrofisica ( INAF ), Laboratoire des technologies de la microélectronique ( LTM ), Université Joseph Fourier - Grenoble 1 ( UJF ) -Centre National de la Recherche Scientifique ( CNRS ), Institut de Microélectronique, Electromagnétisme et Photonique - Laboratoire d'Hyperfréquences et Caractérisation ( IMEP-LAHC ), Université Joseph Fourier - Grenoble 1 ( UJF ) -Institut polytechnique de Grenoble - Grenoble Institute of Technology ( Grenoble INP ) -Institut National Polytechnique de Grenoble ( INPG ) -Université Savoie Mont Blanc ( USMB [Université de Savoie] [Université de Chambéry] ) -Centre National de la Recherche Scientifique ( CNRS ) -Université Grenoble Alpes ( UGA ), Universidad Politécnica de Cataluña, U.S. Army Research Laboratory [Adelphi, MD] ( ARL ), United States Army ( U.S. Army ), Royal Observatory Edinburgh ( ROE ), SRON Netherlands Institute for Space Research ( SRON ), Laboratoire de Météorologie Dynamique (UMR 8539) ( LMD ), Université Pierre et Marie Curie - Paris 6 ( UPMC ) -Institut national des sciences de l'Univers ( INSU - CNRS ) -École polytechnique ( X ) -École des Ponts ParisTech ( ENPC ) -Centre National de la Recherche Scientifique ( CNRS ) -Département des Géosciences - ENS Paris, École normale supérieure - Paris ( ENS Paris ) -École normale supérieure - Paris ( ENS Paris ), Joseph Louis LAGRANGE ( LAGRANGE ), Université Nice Sophia Antipolis ( UNS ), Université Côte d'Azur ( UCA ) -Université Côte d'Azur ( UCA ) -Observatoire de la Côte d'Azur, Université Côte d'Azur ( UCA ) -Centre National de la Recherche Scientifique ( CNRS ), Lunar and Planetary Laboratory [Tucson], Space Research Institute of Austrian Academy of Sciences ( IWF ), Austrian Academy of Sciences ( OeAW ), Centre de Recherche Astrophysique de Lyon ( CRAL ), École normale supérieure - Lyon ( ENS Lyon ) -Université Claude Bernard Lyon 1 ( UCBL ), Université de Lyon-Université de Lyon-Institut national des sciences de l'Univers ( INSU - CNRS ) -Centre National de la Recherche Scientifique ( CNRS ), Center for Human-Computer Interaction ( HCI ), Istituto di Astrofisica e Planetologia Spaziali ( IAPS ), University of Hertfordshire [Hatfield] ( UH ), Laboratoire d'Astrophysique de Bordeaux [Pessac] ( LAB ), Université de Bordeaux ( UB ) -Institut national des sciences de l'Univers ( INSU - CNRS ) -Centre National de la Recherche Scientifique ( CNRS ) -Université de Bordeaux ( UB ) -Institut national des sciences de l'Univers ( INSU - CNRS ) -Centre National de la Recherche Scientifique ( CNRS ), Laboratoire de Physique Atmosphérique et Planétaire ( LPAP ), Centro de Astronomia e Astrofísica da Universidade de Lisboa ( CAAUL ), Universidade de Lisboa ( ULISBOA ), Space Research Centre [Warsaw] ( CBK ), Polska Akademia Nauk ( PAN ), Department of Atmospheric, Oceanic and Planetary Physics [Oxford] ( AOPP ), Mullard Space Science Laboratory ( MSSL ), Max-Planck-Institut für Sonnensystemforschung ( MPS ), Institut de Recherches sur les lois Fondamentales de l'Univers ( IRFU ), Commissariat à l'énergie atomique et aux énergies alternatives ( CEA ) -Université Paris-Saclay, Instituut voor Sterrenkunde, Katholieke Universiteit Leuven ( KU Leuven ), foreign laboratories ( FL ), STFC Rutherford Appleton Laboratory ( RAL ), Science and Technology Facilities Council ( STFC ), Centre for Planetary Sciences [UCL/Birkbeck] ( CPS ), Queen Mary University of London ( QMUL ), Institut d'Astrophysique de Paris ( IAP ), Université Pierre et Marie Curie - Paris 6 ( UPMC ) -Institut national des sciences de l'Univers ( INSU - CNRS ) -Centre National de la Recherche Scientifique ( CNRS ), Dark Cosmology Center, Niels Bohr Institute, University of Copenhagen ( KU ), Computational Science and Engineering Department [Daresbury] ( STFC ), LAEX, Depto. Astrofísica, Centro de Astrobiología, Nelson Mandela Metropolitan University, Nelson Mandela Metropolitan University [Port Elizabeth, South Africa]-Nelson Mandela Metropolitan University [Port Elizabeth, South Africa], Teagasc, Laboratoire d'Astrophysique de Marseille ( LAM ), Aix Marseille Université ( AMU ) -Institut national des sciences de l'Univers ( INSU - CNRS ) -Centre National d'Etudes Spatiales ( CNES ) -Centre National de la Recherche Scientifique ( CNRS ), Fraunhofer-Institute for Applied Solid-State Physics (IAF), Centro de Astrobiologia [Madrid] ( CAB ), Instituto Nacional de Técnica Aeroespacial ( INTA ) -Consejo Superior de Investigaciones Científicas [Spain] ( CSIC ), Jet Propulsion Laboratory ( JPL ), NASA-California Institute of Technology ( CALTECH ), Instituto Nacional de Engenharia, Tecnologia e Inovacco ( INETI ), INETI, Université Pierre et Marie Curie - Paris 6 ( UPMC ), Physiologie de la reproduction et des comportements [Nouzilly] ( PRC ), Institut National de la Recherche Agronomique ( INRA ) -Institut Français du Cheval et de l'Equitation [Saumur]-Université de Tours-Centre National de la Recherche Scientifique ( CNRS ), Università degli Studi di Salerno ( UNISA ), The University of North Carolina at Chapel Hill-Carolina Center for the Genome Sciences, Laboratoire d'astrophysique de l'observatoire de Besançon ( LAOB ), Université de Franche-Comté ( UFC ), Universita degli Studi di Padova = University of Padua = Université de Padoue, Institut d'astrophysique spatiale ( IAS ), Université Paris-Sud - Paris 11 ( UP11 ) -Institut national des sciences de l'Univers ( INSU - CNRS ) -Centre National de la Recherche Scientifique ( CNRS ), Laboratoire d'astrodynamique, d'astrophysique et d'aéronomie de bordeaux ( L3AB ), Université Sciences et Technologies - Bordeaux 1-Institut national des sciences de l'Univers ( INSU - CNRS ) -Centre National de la Recherche Scientifique ( CNRS ) -Université Sciences et Technologies - Bordeaux 1-Institut national des sciences de l'Univers ( INSU - CNRS ) -Centre National de la Recherche Scientifique ( CNRS ) -Observatoire aquitain des sciences de l'univers ( OASU ), Université Sciences et Technologies - Bordeaux 1-Institut national des sciences de l'Univers ( INSU - CNRS ) -Centre National de la Recherche Scientifique ( CNRS ) -Centre National de la Recherche Scientifique ( CNRS ) -Laboratoire d'Astrophysique de Bordeaux [Pessac] ( LAB ), Université de Bordeaux ( UB ) -Institut national des sciences de l'Univers ( INSU - CNRS ) -Centre National de la Recherche Scientifique ( CNRS ) -Université de Bordeaux ( UB ), Institut de génétique et microbiologie [Orsay] ( IGM ), Université Paris-Sud - Paris 11 ( UP11 ) -Centre National de la Recherche Scientifique ( CNRS ), Deutsches Forschungszentrum für Künstliche Intelligenz GmbH ( DFKI ), Consejo Nacional de Investigaciones Científicas y Técnicas ( CONICET ), Centro de Astrofísica da Universidade do Porto ( CAUP ), Institut Universitaire de France ( IUF ), Ministère de l'Éducation nationale, de l’Enseignement supérieur et de la Recherche ( M.E.N.E.S.R. ), Université de Rennes 1 ( UR1 ), Université de Rennes ( UNIV-RENNES ), Laboratoire Hippolyte Fizeau ( FIZEAU ), Université Côte d'Azur ( UCA ) -Université Côte d'Azur ( UCA ) -Institut national des sciences de l'Univers ( INSU - CNRS ) -Observatoire de la Côte d'Azur, Istituto di Fisica dello Spazio Interplanetario CNR (IFSI), Laboratoire de l'Accélérateur Linéaire ( LAL ), Université Paris-Sud - Paris 11 ( UP11 ) -Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Centre National de la Recherche Scientifique ( CNRS ), Centre de recherche en éducation de Nantes ( CREN ), Université de Nantes ( UN ), Universidad del Pais Vasco / Euskal Herriko Unibertsitatea ( UPV/EHU ), NASA Goddard Space Flight Center ( GSFC ), Onsala Space Observatory ( OSO ), Los Alamos National Laboratory ( LANL ), Centre d'Etude de l'Energie Nucléaire ( SCK-CEN ), Institut de Physique du Globe de Paris ( IPGP ), Université Pierre et Marie Curie - Paris 6 ( UPMC ) -Institut national des sciences de l'Univers ( INSU - CNRS ) -IPG PARIS-Université Paris Diderot - Paris 7 ( UPD7 ) -Université de la Réunion ( UR ) -Centre National de la Recherche Scientifique ( CNRS ), Instituto de Astrofísica de Andalucía ( IAA ), Consejo Superior de Investigaciones Científicas [Spain] ( CSIC ), Department of Rheumatology ( LEIDEN - Rhumato ), Department of Rheumatology ( COIMBRA - Rhumato ), Centre Scientifique et Technique du Bâtiment ( CSTB ), INAF - Osservatorio Astrofisico di Arcetri ( OAA ), Centre interdisciplinaire de recherche, culture, éducation, formation, travail ( CIRCEFT ), Université Paris 8 Vincennes-Saint-Denis ( UP8 ) -Université Paris-Est Créteil Val-de-Marne - Paris 12 ( UPEC UP12 ), Institut national des sciences de l'Univers ( INSU - CNRS ) -IPG PARIS-Université Paris Diderot - Paris 7 ( UPD7 ) -Université de la Réunion ( UR ) -Centre National de la Recherche Scientifique ( CNRS ), Centre National de la Recherche Scientifique ( CNRS ), Laboratoire de physique des gaz et des plasmas ( LPGP ), Pontificia Universidad Católica de Chile, Thüringer Landessternwarte Tautenburg ( TLS ), BIBA Bremer Institut für Produktion und Logistik GmbH, Centre Émile Durkheim ( CED ), Université de Bordeaux ( UB ) -Sciences Po-Centre National de la Recherche Scientifique ( CNRS ) -Université de Bordeaux ( UB ) -Sciences Po-Centre National de la Recherche Scientifique ( CNRS ), INAF - Osservatorio Astrofisico di Catania ( OACT ), Institut de Ciencies Fotoniques [Castelldefels] ( ICFO ), Università di Perugia, Royal Holloway [University of London] ( RHUL ), and Low Energy Astrophysics (API, FNWI)

Subjects
Astrofísica, Solar System, Computer science, [SDU.ASTR.EP]Sciences of the Universe [physics]/Astrophysics [astro-ph]/Earth and Planetary Astrophysics [astro-ph.EP], HOT-JUPITER ATMOSPHERES, 7. Clean energy, Space missions, law.invention, Astronomi, astrofysik och kosmologi, Planet, law, Observatory, Astronomy, Astrophysics and Cosmology, Transit (astronomy), Atmospheric science, Exoplanets, IR astronomy, Spectroscopy, Astronomy and Astrophysics, Space and Planetary Science, QC, QB, Eclipse, Earth and Planetary Astrophysics (astro-ph.EP), education.field_of_study, [SDU.ASTR]Sciences of the Universe [physics]/Astrophysics [astro-ph], [ SDU.ASTR.EP ] Sciences of the Universe [physics]/Astrophysics [astro-ph]/Earth and Planetary Astrophysics [astro-ph.EP], Exoplanet, GIANT PLANETS, Physical Sciences, ENERGY-BALANCE, Astrophysics::Earth and Planetary Astrophysics, Population, MU-M, FOS: Physical sciences, F500, Astronomy & Astrophysics, Telescope, INFRARED-EMISSION-SPECTRUM, education, [ SDU.ASTR ] Sciences of the Universe [physics]/Astrophysics [astro-ph], EXTRASOLAR PLANET ATMOSPHERE, Science & Technology, Astronomy, EXOPLANET HD 189733B, HUBBLE-SPACE-TELESCOPE, Astronomía, TRANSMISSION SPECTROSCOPY, 0201 Astronomical And Space Sciences, 13. Climate action, WATER-VAPOR, astro-ph.EP, Astrophysics - Earth and Planetary Astrophysics
Abstract

The discovery of almost 2000 exoplanets has revealed an unexpectedly diverse planet population. Observations to date have shown that our Solar System is certainly not representative of the general population of planets in our Milky Way. The key science questions that urgently need addressing are therefore: What are exoplanets made of? Why are planets as they are? What causes the exceptional diversity observed as compared to the Solar System? EChO (Exoplanet Characterisation Observatory) has been designed as a dedicated survey mission for transit and eclipse spectroscopy capable of observing a large and diverse planet sample within its four-year mission lifetime. EChO can target the atmospheres of super-Earths, Neptune-like, and Jupiter-like planets, in the very hot to temperate zones (planet temperatures of 300K-3000K) of F to M-type host stars. Over the next ten years, several new ground- and space-based transit surveys will come on-line (e.g. NGTS, CHEOPS, TESS, PLATO), which will specifically focus on finding bright, nearby systems. The current rapid rate of discovery would allow the target list to be further optimised in the years prior to EChO's launch and enable the atmospheric characterisation of hundreds of planets. Placing the satellite at L2 provides a cold and stable thermal environment, as well as a large field of regard to allow efficient time-critical observation of targets randomly distributed over the sky. A 1m class telescope is sufficiently large to achieve the necessary spectro-photometric precision. The spectral coverage (0.5-11 micron, goal 16 micron) and SNR to be achieved by EChO, thanks to its high stability and dedicated design, would enable a very accurate measurement of the atmospheric composition and structure of hundreds of exoplanets., Comment: 50 pages, 30 figures. Experimental Astronomy

Published
2015

11. Characteristics of north jovian aurora from STIS FUV spectral images

Author

Gustin, J., Grodent, D., Ray, L. C., Bonfond, B., Bunce, E. J., Nichols, J. D., Ozak, N., Gustin, J., Grodent, D., Ray, L. C., Bonfond, B., Bunce, E. J., Nichols, J. D., and Ozak, N.

Abstract

We analyzed two observations obtained in Jan. 2013, consisting of spatial scans of the jovian north ultraviolet aurora with the HST Space Telescope Imaging Spectrograph (STIS) in the spectroscopic mode. The color ratio (CR) method, which relates the wavelength-dependent absorption of the FUV spectra to the mean energy of the precipitating electrons, allowed us to determine important characteristics of the entire auroral region. The results show that the spatial distribution of the precipitating electron energy is far from uniform. The morning main emission arc is associated with mean energies of around 265 keV, the afternoon main emission (kink region) has energies near 105 keV, while the 'flare' emissions poleward of the main oval are characterized by electrons in the 50-85. keV range. A small scale structure observed in the discontinuity region is related to electrons of 232 keV and the Ganymede footprint shows energies of 157 keV. Interestingly, each specific region shows very similar behavior for the two separate observations.The Io footprint shows a weak but undeniable hydrocarbon absorption, which is not consistent with altitudes of the Io emission profiles (~900 km relative to the 1 bar level) determined from HST-ACS observations. An upward shift of the hydrocarbon homopause of at least 100 km is required to reconcile the high altitude of the emission and hydrocarbon absorption. The relationship between the energy fluxes and the electron energies has been compared to curves obtained from Knight's theory of field-aligned currents. Assuming a fixed electron temperature of 2.5 keV, an electron source population density of ~800 m-3 and ~2400 m-3 is obtained for the morning main emission and kink regions, respectively. Magnetospheric electron densities are lowered for the morning main emission (~600 m-3) if the relativistic version of Knight's theory is applied.Lyman and Werner H2 emission profiles, resulting from secondary electrons produced by precipitation of h

Published
2016

12. The science case for an orbital mission to Uranus: Exploring the origins and evolution of ice giant planets

Author

Arridge, C.S. Achilleos, N. Agarwal, J. Agnor, C.B. Ambrosi, R. André, N. Badman, S.V. Baines, K. Banfield, D. Barthélémy, M. Bisi, M.M. Blum, J. Bocanegra-Bahamon, T. Bonfond, B. Bracken, C. Brandt, P. Briand, C. Briois, C. Brooks, S. Castillo-Rogez, J. Cavalié, T. Christophe, B. Coates, A.J. Collinson, G. Cooper, J.F. Costa-Sitja, M. Courtin, R. Daglis, I.A. De Pater, I. Desai, M. Dirkx, D. Dougherty, M.K. Ebert, R.W. Filacchione, G. Fletcher, L.N. Fortney, J. Gerth, I. Grassi, D. Grodent, D. Grün, E. Gustin, J. Hedman, M. Helled, R. Henri, P. Hess, S. Hillier, J.K. Hofstadter, M.H. Holme, R. Horanyi, M. Hospodarsky, G. Hsu, S. Irwin, P. Jackman, C.M. Karatekin, O. Kempf, S. Khalisi, E. Konstantinidis, K. Krüger, H. Kurth, W.S. Labrianidis, C. Lainey, V. Lamy, L.L. Laneuville, M. Lucchesi, D. Luntzer, A. MacArthur, J. Maier, A. Masters, A. McKenna-Lawlor, S. Melin, H. Milillo, A. Moragas-Klostermeyer, G. Morschhauser, A. Moses, J.I. Mousis, O. Nettelmann, N. Neubauer, F.M. Nordheim, T. Noyelles, B. Orton, G.S. Owens, M. Peron, R. Plainaki, C. Postberg, F. Rambaux, N. Retherford, K. Reynaud, S. Roussos, E. Russell, C.T. Rymer, A.M. Sallantin, R. Sánchez-Lavega, A. Santolik, O. Saur, J. Sayanagi, K.M. Schenk, P. Schubert, J. Sergis, N. Sittler, E.C. Smith, A. Spahn, F. Srama, R. Stallard, T. Sterken, V. Sternovsky, Z. Tiscareno, M. Tobie, G. Tosi, F. Trieloff, M. Turrini, D. Turtle, E.P. Vinatier, S. Wilson, R. Zarka, P.

Subjects
Physics::Space Physics, Astrophysics::Earth and Planetary Astrophysics
Abstract

Giant planets helped to shape the conditions we see in the Solar System today and they account for more than 99% of the mass of the Sun's planetary system. They can be subdivided into the Ice Giants (Uranus and Neptune) and the Gas Giants (Jupiter and Saturn), which differ from each other in a number of fundamental ways. Uranus, in particular is the most challenging to our understanding of planetary formation and evolution, with its large obliquity, low self-luminosity, highly asymmetrical internal field, and puzzling internal structure. Uranus also has a rich planetary system consisting of a system of inner natural satellites and complex ring system, five major natural icy satellites, a system of irregular moons with varied dynamical histories, and a highly asymmetrical magnetosphere. Voyager 2 is the only spacecraft to have explored Uranus, with a flyby in 1986, and no mission is currently planned to this enigmatic system. However, a mission to the uranian system would open a new window on the origin and evolution of the Solar System and would provide crucial information on a wide variety of physicochemical processes in our Solar System. These have clear implications for understanding exoplanetary systems. In this paper we describe the science case for an orbital mission to Uranus with an atmospheric entry probe to sample the composition and atmospheric physics in Uranus' atmosphere. The characteristics of such an orbiter and a strawman scientific payload are described and we discuss the technical challenges for such a mission. This paper is based on a white paper submitted to the European Space Agency's call for science themes for its large-class mission programme in 2013. © 2014 Elsevier Ltd.

Published
2014

13. The far-ultraviolet main auroral emission at Jupiter – Part 2:vertical emission profile

Author

Bonfond, B., Gustin, J., Gérard, J.-C., Grodent, D., Radioti, A., Palmaerts, B., Badman, S. V., Khurana, K. K., Tao, C., Bonfond, B., Gustin, J., Gérard, J.-C., Grodent, D., Radioti, A., Palmaerts, B., Badman, S. V., Khurana, K. K., and Tao, C.

Abstract

The aurorae at Jupiter are made up of many different features associated with a variety of generation mechanisms. The main auroral emission, also known as the main oval, is the most prominent of them as it accounts for approximately half of the total power emitted by the aurorae in the ultraviolet range. The energy of the precipitating electrons is a crucial parameter to characterize the processes at play which give rise to these auroral emissions, and the altitude of the emissions directly depends on this energy. Here we make use of far-UV (FUV) images acquired with the Advanced Camera for Surveys on board the Hubble Space Telescope and spectra acquired with the Space Telescope Imaging Spectrograph to measure the vertical profile of the main emissions. The altitude of the brightness peak as seen above the limb is ~ 400 km, which is significantly higher than the 250 km measured in the post-dusk sector by Galileo in the visible domain. However, a detailed analysis of the effect of hydrocarbon absorption, including both simulations and FUV spectral observations, indicates that FUV apparent vertical profiles should be considered with caution, as these observations are not incompatible with an emission peak located at 250 km. The analysis also calls for spectral observations to be carried out with an optimized geometry in order to remove observational ambiguities.

Published
2015

14. The far-ultraviolet main auroral emission at Jupiter - Part 1:dawn-dusk brightness asymmetries

Author

Bonfond, B., Gustin, J., Gérard, J.-C., Grodent, D., Radioti, A., Palmaerts, B., Badman, S. V., Khurana, K. K., Tao, C., Bonfond, B., Gustin, J., Gérard, J.-C., Grodent, D., Radioti, A., Palmaerts, B., Badman, S. V., Khurana, K. K., and Tao, C.

Abstract

The main auroral emission at Jupiter generally appears as a quasi-closed curtain centered around the magnetic pole. This auroral feature, which accounts for approximately half of the total power emitted by the aurorae in the ultraviolet range, is related to corotation enforcement currents in the middle magnetosphere. Early models for these currents assumed axisymmetry, but significant local time variability is obvious on any image of the Jovian aurorae. Here we use far-UV images from the Hubble Space Telescope to further characterize these variations on a statistical basis. We show that the dusk side sector is ~ 3 times brighter than the dawn side in the southern hemisphere and ~ 1.1 brighter in the northern hemisphere, where the magnetic anomaly complicates the interpretation of the measurements. We suggest that such an asymmetry between the dawn and the dusk sectors could be the result of a partial ring current in the nightside magnetosphere.

Published
2015

17. Auroral signatures of multiple magnetopause reconnection at Saturn

Author

Radioti, A., Grodent, D., Gerard, J. -C., Bonfond, B., Gustin, J., Pryor, W., Jasinski, J. M., and Arridge, C. S.

Subjects
Physics::Plasma Physics, Astrophysics::High Energy Astrophysical Phenomena, Physics::Space Physics, Astrophysics::Solar and Stellar Astrophysics, Astrophysics::Earth and Planetary Astrophysics
Abstract

Auroral observations capture the ionospheric response to dynamics of the whole magnetosphere and may provide evidence of the significance of reconnection at Saturn. Bifurcations of the main dayside auroral emission have been related to reconnection at the magnetopause and their surface is suggested to represent the amount of newly opened flux. This work is the first presentation of multiple brightenings of these auroral features based on Cassini ultraviolet auroral observations. In analogy to the terrestrial case, we propose a process, in which a magnetic flux tube reconnects with other flux tubes at multiple sites. This scenario predicts the observed multiple brightenings, it is consistent with subcorotating auroral features which separate from the main emission, and it suggests north-south auroral asymmetries. We demonstrate that the conditions for multiple magnetopause reconnection can be satisfied at Saturn, like at Earth.

Published
2013

18. Multispectral simultaneous diagnosis of Saturn's aurorae throughout a planetary rotation

Author

Lamy, L., Prang��, R., Pryor, W., Gustin, J., Badman, S. V., Melin, H., Stallard, T., Mitchell, D. G., Brandt, P. C., Laboratoire d'études spatiales et d'instrumentation en astrophysique (LESIA), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Central Arizona College, Laboratoire de Physique Atmosphérique et Planétaire (LPAP), Université de Liège, Lancaster University, Department of Physics and Astronomy [Leicester], University of Leicester, Johns Hopkins University Applied Physics Laboratory [Laurel, MD] (APL), Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC), Institute of Space and Astronautical Science (ISAS), and Japan Aerospace Exploration Agency [Sagamihara] (JAXA)

Subjects
Earth and Planetary Astrophysics (astro-ph.EP), Saturn, [SDU.ASTR]Sciences of the Universe [physics]/Astrophysics [astro-ph], Physics::Space Physics, magnetosphere, [SDU.ASTR.EP]Sciences of the Universe [physics]/Astrophysics [astro-ph]/Earth and Planetary Astrophysics [astro-ph.EP], FOS: Physical sciences, Astrophysics::Earth and Planetary Astrophysics, aurorae, radio emissions, Astrophysics - Earth and Planetary Astrophysics
Abstract

International audience; From 27 to 28 January 2009, the Cassini spacecraft remotely acquired combined observations of Saturn's southern aurorae at radio, ultraviolet, and infrared wavelengths, while monitoring ion injections in the middle magnetosphere from energetic neutral atoms. Simultaneous measurements included the sampling of a full planetary rotation, a relevant timescale to investigate auroral emissions driven by processes internal to the magnetosphere. In addition, this interval coincidentally matched a powerful substorm-like event in the magnetotail, which induced an overall dawnside intensification of the magnetospheric and auroral activity. We comparatively analyze this unique set of measurements to reach a comprehensive view of kronian auroral processes over the investigated timescale. We identify three source regions for the atmospheric aurorae, including a main oval associated with the bulk of Saturn Kilometric Radiation (SKR), together with polar and equatorward emissions. These observations reveal the coexistence of corotational and subcorototational dynamics of emissions associated with the main auroral oval. Precisely, we show that the atmospheric main oval hosts short-lived subcorotating isolated features together with a bright, longitudinally extended, corotating region locked at the southern SKR phase. We assign the substorm-like event to a regular, internally driven, nightside ion injection possibly triggered by a plasmoid ejection. We also investigate the total auroral energy budget, from the power input to the atmosphere, characterized by precipitating electrons up to 20 keV, to its dissipation through the various radiating processes. Finally, through simulations, we confirm the search-light nature of the SKR rotational modulation and we show that SKR arcs relate to isolated auroral spots. We characterize which radio sources are visible from the spacecraft and we estimate the fraction of visible southern power to a few percent. The resulting findings are discussed in the frame of pending questions as the persistence of a corotating field-aligned current system within a subcorotating magnetospheric cold plasma, the occurrence of plasmoid activity, and the comparison of auroral fluxes radiated at different wavelengths.

Published
2013

20. Simultaneous Cassini VIMS and UVIS observations of Saturn's southern aurora:comparing emissions from H, H2 and H3+ at a high spatial resolution

Author

Melin, H., Stallard, T., Miller, S., Gustin, J., Galand, M., Badman, S. V., Pryor, W. R., O'donoghue, J., Brown, R. H., and Baines, K. H.

Abstract

Here, for the first time, temporally coincident and spatially overlapping Cassini VIMS and UVIS observations of Saturn's southern aurora are presented. Ultraviolet auroral H and H2 emissions from UVIS are compared to infrared H3+ emission from VIMS. The auroral emission is structured into three arcs – H, H2 and H3+ are morphologically identical in the bright main auroral oval (∼73°S), but there is an equatorward arc that is seen predominantly in H (∼70°S), and a poleward arc (∼74°S) that is seen mainly in H2 and H3+. These observations indicate that, for the main auroral oval, UV emission is a good proxy for the infrared H3+ morphology (and vice versa), but for emission either poleward or equatorward this is no longer true. Hence, simultaneous UV/IR observations are crucial for completing the picture of how the atmosphere interacts with the magnetosphere.

Published
2011

23. The science case for an orbital mission to Uranus: Exploring the origins and evolution of ice giant planets

Author

Arridge, C. S., Achilleos, N., Agarwal, J., Agnor, C. B., Ambrosi, R., Andre, N., Badman, S. V., Baines, K., Banfield, D., Barthelemy, M., Bisi, M. M., Blum, J., Bocanegra-Bahamon, T., Bonfond, B. ., Bracken, C., Brandt, P., Briand, C., Briois, C., Brooks, S., Castillo-Rogez, J., Cavalie, T., Christophe, B., Coates, A. J., Collinson, G., Cooper, J. F., Costa-Sitja, M., Courtin, R., Daglis, I. A., De Pater, I., Desai, M., Dirkx, D., Dougherty, M. K., Ebert, R. W., Filacchione, G., Fletcher, L. N., Fortney, J., Gerth, I., Grassi, D., Grodent, D., Grun, E., Gustin, J., Hedman, M., Helled, R., Henri, P., Hess, S., Hillier, J. K., Hofstadter, M. H., Holme, R., Horanyi, M., Hospodarsky, G., Hsu, S., Irwin, P., Jackman, C. M., Karatekin, O., Kempf, S., Khalisi, E., Konstantinidis, K., Kruger, H., Kurth, W. S., Labrianidis, C., Lainey, V., Lamy, L. L., Laneuville, M., Lucchesi, D., Luntzer, A., MacArthur, J., Maier, A., Masters, A., McKenna-Lawlor, S., Melin, H., Milillo, A., Moragas-Klostermeyer, G., Morschhauser, A., Moses, J. I., Mousis, O., Nettelmann, N., Neubauer, F. M., Nordheim, T., Noyelles, B., Orton, G. S., Owens, M., Peron, R., Plainaki, C., Postberg, F., Rambaux, N., Retherford, K., Reynaud, S., Roussos, E., Russell, C. T., Rymer, Am., Sallantin, R., Sanchez-Lavega, A., Santolik, O., Saur, J., Sayanagi, Km., Schenk, P., Schubert, J., Sergis, N., Sittler, E. C., Smith, A., Spahn, F., Srama, R., Stallard, T., Sterken, V., Sternovsky, Z., Tiscareno, M., Tobie, G., Tosi, F., Trieloff, M., Turrini, D., Turtle, E. P., Vinatier, S., Wilson, R., Zarkat, P., Arridge, C. S., Achilleos, N., Agarwal, J., Agnor, C. B., Ambrosi, R., Andre, N., Badman, S. V., Baines, K., Banfield, D., Barthelemy, M., Bisi, M. M., Blum, J., Bocanegra-Bahamon, T., Bonfond, B. ., Bracken, C., Brandt, P., Briand, C., Briois, C., Brooks, S., Castillo-Rogez, J., Cavalie, T., Christophe, B., Coates, A. J., Collinson, G., Cooper, J. F., Costa-Sitja, M., Courtin, R., Daglis, I. A., De Pater, I., Desai, M., Dirkx, D., Dougherty, M. K., Ebert, R. W., Filacchione, G., Fletcher, L. N., Fortney, J., Gerth, I., Grassi, D., Grodent, D., Grun, E., Gustin, J., Hedman, M., Helled, R., Henri, P., Hess, S., Hillier, J. K., Hofstadter, M. H., Holme, R., Horanyi, M., Hospodarsky, G., Hsu, S., Irwin, P., Jackman, C. M., Karatekin, O., Kempf, S., Khalisi, E., Konstantinidis, K., Kruger, H., Kurth, W. S., Labrianidis, C., Lainey, V., Lamy, L. L., Laneuville, M., Lucchesi, D., Luntzer, A., MacArthur, J., Maier, A., Masters, A., McKenna-Lawlor, S., Melin, H., Milillo, A., Moragas-Klostermeyer, G., Morschhauser, A., Moses, J. I., Mousis, O., Nettelmann, N., Neubauer, F. M., Nordheim, T., Noyelles, B., Orton, G. S., Owens, M., Peron, R., Plainaki, C., Postberg, F., Rambaux, N., Retherford, K., Reynaud, S., Roussos, E., Russell, C. T., Rymer, Am., Sallantin, R., Sanchez-Lavega, A., Santolik, O., Saur, J., Sayanagi, Km., Schenk, P., Schubert, J., Sergis, N., Sittler, E. C., Smith, A., Spahn, F., Srama, R., Stallard, T., Sterken, V., Sternovsky, Z., Tiscareno, M., Tobie, G., Tosi, F., Trieloff, M., Turrini, D., Turtle, E. P., Vinatier, S., Wilson, R., and Zarkat, P.

Abstract

Giant planets helped to shape the conditions we see in the Solar System today and they account for more than 99% of the mass of the Sun's planetary system. They can be subdivided into the Ice Giants (Uranus and Neptune) and the Gas Giants (Jupiter and Saturn), which differ from each other in a number of fundamental ways. Uranus, in particular is the most challenging to our understanding of planetary formation and evolution, with its large obliquity, low self-luminosity, highly asymmetrical internal field, and puzzling internal structure. Uranus also has a rich planetary system consisting of a system of inner natural satellites and complex ring system, five major natural icy satellites, a system of irregular moons with varied dynamical histories, and a highly asymmetrical magnetosphere. Voyager 2 is the only spacecraft to have explored Uranus, with a flyby in 1986, and no mission is currently planned to this enigmatic system. However, a mission to the uranian system would open a new window on the origin and evolution of the Solar System and would provide crucial information on a wide variety of physicochemical processes in our Solar System. These have clear implications for understanding exoplanetary systems. In this paper we describe the science case for an orbital mission to Uranus with an atmospheric entry probe to sample the composition and atmospheric physics in Uranus' atmosphere. The characteristics of such an orbiter and a strawman scientific payload are described and we discuss the technical challenges for such a mission. This paper is based on a white paper submitted to the European Space Agency's call for science themes for its large-class mission programme in 2013. (C) 2014 Published by Elsevier Ltd.

Published
2014

24. The science case for an orbital mission to Uranus:exploring the origins and evolution of ice giant planets

Author

Arridge, C. S., Achilleos, N., Agarwal, J., Agnor, C. B., Ambrosi, R., Andre, N., Badman, S. V., Baines, K., Banfield, D., Barthelemy, M., Bisi, M. M., Blum, J., Bocanegra-Bahamon, T., Bonfond, B. ., Bracken, C., Brandt, P., Briand, C., Briois, C., Brooks, S., Castillo-Rogez, J., Cavalie, T., Christophe, B., Coates, A. J., Collinson, G., Cooper, J. F., Costa-Sitja, M., Courtin, R., Daglis, I. A., De Pater, I., Desai, M., Dirkx, D., Dougherty, M. K., Ebert, R. W., Filacchione, G., Fletcher, L. N., Fortney, J., Gerth, I., Grassi, D., Grodent, D., Grun, E., Gustin, J., Hedman, M., Helled, R., Henri, P., Hess, S., Hillier, J. K., Hofstadter, M. H., Holme, R., Horanyi, M., Hospodarsky, G., Hsu, S., Irwin, P., Jackman, C. M., Karatekin, O., Kempf, S., Khalisi, E., Konstantinidis, K., Kruger, H., Kurth, W. S., Labrianidis, C., Lainey, V., Lamy, L. L., Laneuville, M., Lucchesi, D., Luntzer, A., MacArthur, J., Maier, A., Masters, A., McKenna-Lawlor, S., Melin, H., Milillo, A., Moragas-Klostermeyer, G., Morschhauser, A., Moses, J. I., Mousis, O., Nettelmann, N., Neubauer, F. M., Nordheim, T., Noyelles, B., Orton, G. S., Owens, M., Peron, R., Plainaki, C., Postberg, F., Rambaux, N., Retherford, K., Reynaud, S., Roussos, E., Russell, C. T., Rymer, Am., Sallantin, R., Sanchez-Lavega, A., Santolik, O., Saur, J., Sayanagi, Km., Schenk, P., Schubert, J., Sergis, N., Sittler, E. C., Smith, A., Spahn, F., Srama, R., Stallard, T., Sterken, V., Sternovsky, Z., Tiscareno, M., Tobie, G., Tosi, F., Trieloff, M., Turrini, D., Turtle, E. P., Vinatier, S., Wilson, R., Zarkat, P., Arridge, C. S., Achilleos, N., Agarwal, J., Agnor, C. B., Ambrosi, R., Andre, N., Badman, S. V., Baines, K., Banfield, D., Barthelemy, M., Bisi, M. M., Blum, J., Bocanegra-Bahamon, T., Bonfond, B. ., Bracken, C., Brandt, P., Briand, C., Briois, C., Brooks, S., Castillo-Rogez, J., Cavalie, T., Christophe, B., Coates, A. J., Collinson, G., Cooper, J. F., Costa-Sitja, M., Courtin, R., Daglis, I. A., De Pater, I., Desai, M., Dirkx, D., Dougherty, M. K., Ebert, R. W., Filacchione, G., Fletcher, L. N., Fortney, J., Gerth, I., Grassi, D., Grodent, D., Grun, E., Gustin, J., Hedman, M., Helled, R., Henri, P., Hess, S., Hillier, J. K., Hofstadter, M. H., Holme, R., Horanyi, M., Hospodarsky, G., Hsu, S., Irwin, P., Jackman, C. M., Karatekin, O., Kempf, S., Khalisi, E., Konstantinidis, K., Kruger, H., Kurth, W. S., Labrianidis, C., Lainey, V., Lamy, L. L., Laneuville, M., Lucchesi, D., Luntzer, A., MacArthur, J., Maier, A., Masters, A., McKenna-Lawlor, S., Melin, H., Milillo, A., Moragas-Klostermeyer, G., Morschhauser, A., Moses, J. I., Mousis, O., Nettelmann, N., Neubauer, F. M., Nordheim, T., Noyelles, B., Orton, G. S., Owens, M., Peron, R., Plainaki, C., Postberg, F., Rambaux, N., Retherford, K., Reynaud, S., Roussos, E., Russell, C. T., Rymer, Am., Sallantin, R., Sanchez-Lavega, A., Santolik, O., Saur, J., Sayanagi, Km., Schenk, P., Schubert, J., Sergis, N., Sittler, E. C., Smith, A., Spahn, F., Srama, R., Stallard, T., Sterken, V., Sternovsky, Z., Tiscareno, M., Tobie, G., Tosi, F., Trieloff, M., Turrini, D., Turtle, E. P., Vinatier, S., Wilson, R., and Zarkat, P.

Abstract

Giant planets helped to shape the conditions we see in the Solar System today and they account for more than 99% of the mass of the Sun's planetary system. They can be subdivided into the Ice Giants (Uranus and Neptune) and the Gas Giants (Jupiter and Saturn), which differ from each other in a number of fundamental ways. Uranus, in particular is the most challenging to our understanding of planetary formation and evolution, with its large obliquity, low self-luminosity, highly asymmetrical internal field, and puzzling internal structure. Uranus also has a rich planetary system consisting of a system of inner natural satellites and complex ring system, five major natural icy satellites, a system of irregular moons with varied dynamical histories, and a highly asymmetrical magnetosphere. Voyager 2 is the only spacecraft to have explored Uranus, with a flyby in 1986, and no mission is currently planned to this enigmatic system. However, a mission to the uranian system would open a new window on the origin and evolution of the Solar System and would provide crucial information on a wide variety of physicochemical processes in our Solar System. These have clear implications for understanding exoplanetary systems. In this paper we describe the science case for an orbital mission to Uranus with an atmospheric entry probe to sample the composition and atmospheric physics in Uranus' atmosphere. The characteristics of such an orbiter and a strawman scientific payload are described and we discuss the technical challenges for such a mission. This paper is based on a white paper submitted to the European Space Agency's call for science themes for its large-class mission programme in 2013. (C) 2014 Published by Elsevier Ltd.

Published
2014

25. The science case for an orbital mission to Uranus: Exploring the origins and evolution of ice giant planets

Author

Arridge, C.S., Achilleos, N., Agarwal, J., Agnor, C.B., Ambrosi, R., André, N., Badman, S.V., Baines, K., Banfield, D., Barthélémy, M., Bisi, M.M., Blum, J., Bocanegra-Bahamon, T., Bonfond, B., Bracken, C., Brandt, P., Briand, C., Briois, C., Brooks, S., Castillo-Rogez, J., Cavalié, T., Christophe, B., Coates, A.J., Collinson, G., Cooper, J.F., Costa-Sitja, M., Courtin, R., Daglis, I.A., De Pater, I., Desai, M., Dirkx, D., Dougherty, M.K., Ebert, R.W., Filacchione, G., Fletcher, L.N., Fortney, J., Gerth, I., Grassi, D., Grodent, D., Grün, E., Gustin, J., Hedman, M., Helled, R., Henri, P., Hess, S., Hillier, Jon K., Hofstadter, M.H., Holme, R., Horanyi, M., Hospodarsky, G., Hsu, S., Irwin, P., Jackman, C.M., Karatekin, O., Kempf, S., Khalisi, E., Konstantinidis, K., Krüger, H., Kurth, W.S., Labrianidis, C., Lainey, V., Lamy, L.L., Laneuville, M., Lucchesi, D., Luntzer, A., MacArthur, J., Maier, A., Masters, A., McKenna-Lawlor, S., Melin, H., Milillo, A., Moragas-Klostermeyer, G., Morschhauser, A., Moses, J.I., Mousis, O., Nettelmann, N., Neubauer, F.M., Nordheim, T., Noyelles, B., Orton, G.S., Owens, M., Peron, R., Plainaki, C., Postberg, F., Rambaux, N., Retherford, K., Reynaud, S., Roussos, E., Russell, C.T., Rymer, A.M., Sallantin, R., Sánchez-Lavega, A., Santolik, O., Saur, J., Sayanagi, K.M., Schenk, P., Schubert, J., Sergis, N., Sittler, E.C., Smith, A., Spahn, F., Srama, R., Stallard, T., Sterken, V., Sternovsky, Z., Tiscareno, M., Tobie, G., Tosi, F., Trieloff, M., Turrini, D., Turtle, E.P., Vinatier, S., Wilson, R., Zarka, P., Arridge, C.S., Achilleos, N., Agarwal, J., Agnor, C.B., Ambrosi, R., André, N., Badman, S.V., Baines, K., Banfield, D., Barthélémy, M., Bisi, M.M., Blum, J., Bocanegra-Bahamon, T., Bonfond, B., Bracken, C., Brandt, P., Briand, C., Briois, C., Brooks, S., Castillo-Rogez, J., Cavalié, T., Christophe, B., Coates, A.J., Collinson, G., Cooper, J.F., Costa-Sitja, M., Courtin, R., Daglis, I.A., De Pater, I., Desai, M., Dirkx, D., Dougherty, M.K., Ebert, R.W., Filacchione, G., Fletcher, L.N., Fortney, J., Gerth, I., Grassi, D., Grodent, D., Grün, E., Gustin, J., Hedman, M., Helled, R., Henri, P., Hess, S., Hillier, Jon K., Hofstadter, M.H., Holme, R., Horanyi, M., Hospodarsky, G., Hsu, S., Irwin, P., Jackman, C.M., Karatekin, O., Kempf, S., Khalisi, E., Konstantinidis, K., Krüger, H., Kurth, W.S., Labrianidis, C., Lainey, V., Lamy, L.L., Laneuville, M., Lucchesi, D., Luntzer, A., MacArthur, J., Maier, A., Masters, A., McKenna-Lawlor, S., Melin, H., Milillo, A., Moragas-Klostermeyer, G., Morschhauser, A., Moses, J.I., Mousis, O., Nettelmann, N., Neubauer, F.M., Nordheim, T., Noyelles, B., Orton, G.S., Owens, M., Peron, R., Plainaki, C., Postberg, F., Rambaux, N., Retherford, K., Reynaud, S., Roussos, E., Russell, C.T., Rymer, A.M., Sallantin, R., Sánchez-Lavega, A., Santolik, O., Saur, J., Sayanagi, K.M., Schenk, P., Schubert, J., Sergis, N., Sittler, E.C., Smith, A., Spahn, F., Srama, R., Stallard, T., Sterken, V., Sternovsky, Z., Tiscareno, M., Tobie, G., Tosi, F., Trieloff, M., Turrini, D., Turtle, E.P., Vinatier, S., Wilson, R., and Zarka, P.

Abstract

Giant planets helped to shape the conditions we see in the Solar System today and they account for more than 99% of the mass of the Sun's planetary system. They can be subdivided into the Ice Giants (Uranus and Neptune) and the Gas Giants (Jupiter and Saturn), which differ from each other in a number of fundamental ways. Uranus, in particular is the most challenging to our understanding of planetary formation and evolution, with its large obliquity, low self-luminosity, highly asymmetrical internal field, and puzzling internal structure. Uranus also has a rich planetary system consisting of a system of inner natural satellites and complex ring system, five major natural icy satellites, a system of irregular moons with varied dynamical histories, and a highly asymmetrical magnetosphere. Voyager 2 is the only spacecraft to have explored Uranus, with a flyby in 1986, and no mission is currently planned to this enigmatic system. However, a mission to the uranian system would open a new window on the origin and evolution of the Solar System and would provide crucial information on a wide variety of physicochemical processes in our Solar System. These have clear implications for understanding exoplanetary systems. In this paper we describe the science case for an orbital mission to Uranus with an atmospheric entry probe to sample the composition and atmospheric physics in Uranus' atmosphere. The characteristics of such an orbiter and a strawman scientific payload are described and we discuss the technical challenges for such a mission. This paper is based on a white paper submitted to the European Space Agency's call for science themes for its large-class mission programme in 2013. © 2014 Elsevier Ltd.

Published
2014

45. Tumor necrosis factor employs a protein-tyrosine phosphatase to inhibit activation of KDR and vascular endothelial cell growth factor-induced endothelial cell proliferation.

Author

Guo, D Q, Wu, L W, Dunbar, J D, Ozes, O N, Mayo, L D, Kessler, K M, Gustin, J A, Baerwald, M R, Jaffe, E A, Warren, R S, and Donner, D B

Abstract

Vascular endothelial cell growth factor (VEGF) binds to and promotes the activation of one of its receptors, KDR. Once activated, KDR induces the tyrosine phosphorylation of cytoplasmic signaling proteins that are important to endothelial cell proliferation. In human umbilical vein endothelial cells (HUVECs), tumor necrosis factor (TNF) inhibits the phosphorylation and activation of KDR. The ability of TNF to diminish VEGF-stimulated KDR activity was impaired by sodium orthovanadate, suggesting that the inhibitory activity of TNF was mediated by a protein-tyrosine phosphatase. KDR-initiated responses specifically associated with endothelial cell proliferation, mitogen-activated protein kinase activation and DNA synthesis, were also inhibited by TNF, and this was reversed by sodium orthovanadate. Stimulation of HUVECs with TNF induced association of the SHP-1 protein-tyrosine phosphatase with KDR, identifying this phosphatase as a candidate negative regulator of VEGF signal transduction. Heterologous receptor inactivation mediated by a protein-tyrosine phosphatase provides insight into how TNF may inhibit endothelial cell proliferative responses and modulate angiogenesis in pathological settings.

Published
2000

46. Elastase and the LasA protease of Pseudomonas aeruginosa are secreted with their propeptides.

Author

Kessler, E, Safrin, M, Gustin, J K, and Ohman, D E

Abstract

Pseudomonas aeruginosa elastase and the LasA protease are synthesized as preproenzymes with long amino-terminal propeptides. The elastase propeptide is cleaved autocatalytically in the periplasm to form a transient, inactive elastase-propeptide complex. In contrast, the processing of proLasA does not involve autoproteolysis. In this study, we analyzed short-term P. aeruginosa cultures under conditions that minimize proteolysis and found that an elastase-propeptide complex is secreted, and then the propeptide is degraded extracellularly, apparently by elastase itself. LasA protease, on the other hand, was found to be secreted in its unprocessed 42-kDa proenzyme form. The processing of proLasA occurred extracellularly, and it involved the transient appearance of a 28-kDa intermediate and the respective 14-kDa LasA propeptide fragment. The processing of proLasA in P. aeruginosa strain FRD740, which does not express elastase, also proceeded via the 28-kDa intermediate, but the rate of processing was greatly reduced. This low rate of proLasA processing was further reduced when the activity of a secreted lysine-specific protease was blocked. Purified secreted proteases of P. aeruginosa (i.e. elastase, the lysine-specific protease, and alkaline proteinase) converted proLasA to the active enzyme. Processing by elastase and the lysine-specific enzyme, but not by alkaline proteinase, proceeded via the 28-kDa intermediate, and both were far more effective than alkaline proteinase in converting proLasA to the mature enzyme. We conclude that LasA protease and elastase are secreted with their propeptides, which are then degraded by secreted proteases of P. aeruginosa. In addition to their other functions, the propeptides may play a role in targeting their respective enzymes across the outer membrane.

Published
1998

47. The EChO science case

Author

Tinetti, Giovanna, Drossart, Pierre, Eccleston, Paul, Hartogh, Paul, Isaak, Kate, Linder, Martin, Lovis, Christophe, Micela, Giusi, Ollivier, Marc, Puig, Ludovic, Ribas, Ignasi, Snellen, Ignas, Swinyard, Bruce, Allard, France, Barstow, Joanna, Cho, James, Coustenis, Athena, Cockell, Charles, Correia, Alexandre, Decin, Leen, de Kok, Remco, Deroo, Pieter, Encrenaz, Therese, Forget, Francois, Glasse, Alistair, Griffith, Caitlin, Guillot, Tristan, Koskinen, Tommi, Lammer, Helmut, Leconte, Jeremy, Maxted, Pierre, Mueller-Wodarg, Ingo, Nelson, Richard, North, Chris, Pallé, Enric, Pagano, Isabella, Piccioni, Guseppe, Pinfield, David, Selsis, Franck, Sozzetti, Alessandro, Stixrude, Lars, Tennyson, Jonathan, Turrini, Diego, Zapatero-Osorio, Mariarosa, Beaulieu, Jean-Philippe, Grodent, Denis, Guedel, Manuel, Luz, David, Nørgaard-Nielsen, Hans Ulrik, Ray, Tom, Rickman, Hans, Selig, Avri, Swain, Mark, Banaszkiewicz, Marek, Barlow, Mike, Bowles, Neil, Branduardi-Raymont, Graziella, du Foresto, Vincent Coudé, Gerard, Jean-Claude, Gizon, Laurent, Hornstrup, Allan, Jarchow, Christopher, Kerschbaum, Franz, Kovacs, Géza, Lagage, Pierre-Olivier, Lim, Tanya, Lopez-Morales, Mercedes, Malaguti, Giuseppe, Pace, Emanuele, Pascale, Enzo, Vandenbussche, Bart, Wright, Gillian, Zapata, Gonzalo Ramos, Adriani, Alberto, Azzollini, Ruymán, Balado, Ana, Bryson, Ian, Burston, Raymond, Colomé, Josep, Crook, Martin, Di Giorgio, Anna, Griffin, Matt, Hoogeveen, Ruud, Ottensamer, Roland, Irshad, Ranah, Middleton, Kevin, Morgante, Gianluca, Pinsard, Frederic, Rataj, Mirek, Reess, Jean-Michel, Savini, Giorgio, Schrader, Jan-Rutger, Stamper, Richard, Winter, Berend, Abe, L., Abreu, M., Achilleos, N., Ade, P., Adybekian, V., Affer, L., Agnor, C., Agundez, M., Alard, C., Alcala, J., Allende Prieto, C., Alonso Floriano, F. J., Altieri, F., Alvarez Iglesias, C. A., Amado, P., Andersen, A., Aylward, A., Baffa, C., Bakos, G., Ballerini, P., Banaszkiewicz, M., Barber, R. J., Barrado, D., Barton, E. J., Batista, V., Bellucci, G., Belmonte Avilés, J. A., Berry, D., Bézard, B., Biondi, D., Błęcka, M., Boisse, I., Bonfond, B., Bordé, P., Börner, P., Bouy, H., Brown, L., Buchhave, L., Budaj, J., Bulgarelli, A., Burleigh, M., Cabral, A., Capria, M. T., Cassan, A., Cavarroc, C., Cecchi-Pestellini, C., Cerulli, R., Chadney, J., Chamberlain, S., Charnoz, S., Christian Jessen, N., Ciaravella, A., Claret, A., Claudi, R., Coates, A., Cole, R., Collura, A., Cordier, D., Covino, E., Danielski, C., Damasso, M., Deeg, H. J., Delgado-Mena, E., Del Vecchio, C., Demangeon, O., De Sio, A., De Wit, J., Dobrijévic, M., Doel, P., Dominic, C., Dorfi, E., Eales, S., Eiroa, C., Espinoza Contreras, M., Esposito, M., Eymet, V., Fabrizio, N., Fernández, M., Femenía Castella, B., Figueira, P., Filacchione, G., Fletcher, L., Focardi, M., Fossey, S., Fouqué, P., Frith, J., Galand, M., Gambicorti, L., Gaulme, P., García López, R. J., Garcia-Piquer, A., Gear, W., Gerard, J.-C., Gesa, L., Giani, E., Gianotti, F., Gillon, M., Giro, E., Giuranna, M., Gomez, H., Gomez-Leal, I., Gonzalez Hernandez, J., González Merino, B., Graczyk, R., Grassi, D., Guardia, J., Guio, P., Gustin, J., Hargrave, P., Haigh, J., Hébrard, E., Heiter, U., Heredero, R. L., Herrero, E., Hersant, F., Heyrovsky, D., Hollis, M., Hubert, B., Hueso, R., Israelian, G., Iro, N., Irwin, P., Jacquemoud, S., Jones, G., Jones, H., Justtanont, K., Kehoe, T., Kerschbaum, F., Kerins, E., Kervella, P., Kipping, D., Koskinen, T., Krupp, N., Lahav, O., Laken, B., Lanza, N., Lellouch, E., Leto, G., Licandro Goldaracena, J., Lithgow-Bertelloni, C., Liu, S. J., Lo Cicero, U., Lodieu, N., Lognonné, P., Lopez-Puertas, M., Lopez-Valverde, M. A., Lundgaard Rasmussen, I., Luntzer, A., Machado, P., MacTavish, C., Maggio, A., Maillard, J.-P., Magnes, W., Maldonado, J., Mall, U., Marquette, J.-B., Mauskopf, P., Massi, F., Maurin, A.-S., Medvedev, A., Michaut, C., Miles-Paez, P., Montalto, M., Montañés Rodríguez, P., Monteiro, M., Montes, D., Morais, H., Morales, J. C., Morales-Calderón, M., Morello, G., Moro Martín, A., Moses, J., Moya Bedon, A., Murgas Alcaino, F., Oliva, E., Orton, G., Palla, F., Pancrazzi, M., Pantin, E., Parmentier, V., Parviainen, H., Peña Ramírez, K. Y., Peralta, J., Perez-Hoyos, S., Petrov, R., Pezzuto, S., Pietrzak, R., Pilat-Lohinger, E., Piskunov, N., Prinja, R., Prisinzano, L., Polichtchouk, I., Poretti, E., Radioti, A., Ramos, A. A., Rank-Lüftinger, T., Read, P., Readorn, K., Rebolo López, R., Rebordão, J., Rengel, M., Rezac, L., Rocchetto, M., Rodler, F., Sánchez Béjar, V. J., Sanchez Lavega, A., Sanromá, E., Santos, N., Sanz Forcada, J., Scandariato, G., Schmider, F.-X., Scholz, A., Scuderi, S., Sethenadh, J., Shore, S., Showman, A., Sicardy, B., Sitek, P., Smith, A., Soret, L., Sousa, S., Stiepen, A., Stolarski, M., Strazzulla, G., Tabernero, H. M., Tanga, P., Tecsa, M., Temple, J., Terenzi, L., Tessenyi, M., Testi, L., Thompson, S., Thrastarson, H., Tingley, B. W., Trifoglio, M., Martín Torres, J., Tozzi, A., Turrini, D., Varley, R., Vakili, F., de Val-Borro, M., Valdivieso, M. L., Venot, O., Villaver, E., Vinatier, S., Viti, S., Waldmann, I., Waltham, D., Ward-Thompson, D., Waters, R., Watkins, C., Watson, D., Wawer, P., Wawrzaszk, A., White, G. J., Widemann, T., Winek, W., Wiśniowski, T., Yelle, R., Yung, Y., Yurchenko, S. N., Tinetti, Giovanna, Drossart, Pierre, Eccleston, Paul, Hartogh, Paul, Isaak, Kate, Linder, Martin, Lovis, Christophe, Micela, Giusi, Ollivier, Marc, Puig, Ludovic, Ribas, Ignasi, Snellen, Ignas, Swinyard, Bruce, Allard, France, Barstow, Joanna, Cho, James, Coustenis, Athena, Cockell, Charles, Correia, Alexandre, Decin, Leen, de Kok, Remco, Deroo, Pieter, Encrenaz, Therese, Forget, Francois, Glasse, Alistair, Griffith, Caitlin, Guillot, Tristan, Koskinen, Tommi, Lammer, Helmut, Leconte, Jeremy, Maxted, Pierre, Mueller-Wodarg, Ingo, Nelson, Richard, North, Chris, Pallé, Enric, Pagano, Isabella, Piccioni, Guseppe, Pinfield, David, Selsis, Franck, Sozzetti, Alessandro, Stixrude, Lars, Tennyson, Jonathan, Turrini, Diego, Zapatero-Osorio, Mariarosa, Beaulieu, Jean-Philippe, Grodent, Denis, Guedel, Manuel, Luz, David, Nørgaard-Nielsen, Hans Ulrik, Ray, Tom, Rickman, Hans, Selig, Avri, Swain, Mark, Banaszkiewicz, Marek, Barlow, Mike, Bowles, Neil, Branduardi-Raymont, Graziella, du Foresto, Vincent Coudé, Gerard, Jean-Claude, Gizon, Laurent, Hornstrup, Allan, Jarchow, Christopher, Kerschbaum, Franz, Kovacs, Géza, Lagage, Pierre-Olivier, Lim, Tanya, Lopez-Morales, Mercedes, Malaguti, Giuseppe, Pace, Emanuele, Pascale, Enzo, Vandenbussche, Bart, Wright, Gillian, Zapata, Gonzalo Ramos, Adriani, Alberto, Azzollini, Ruymán, Balado, Ana, Bryson, Ian, Burston, Raymond, Colomé, Josep, Crook, Martin, Di Giorgio, Anna, Griffin, Matt, Hoogeveen, Ruud, Ottensamer, Roland, Irshad, Ranah, Middleton, Kevin, Morgante, Gianluca, Pinsard, Frederic, Rataj, Mirek, Reess, Jean-Michel, Savini, Giorgio, Schrader, Jan-Rutger, Stamper, Richard, Winter, Berend, Abe, L., Abreu, M., Achilleos, N., Ade, P., Adybekian, V., Affer, L., Agnor, C., Agundez, M., Alard, C., Alcala, J., Allende Prieto, C., Alonso Floriano, F. J., Altieri, F., Alvarez Iglesias, C. A., Amado, P., Andersen, A., Aylward, A., Baffa, C., Bakos, G., Ballerini, P., Banaszkiewicz, M., Barber, R. J., Barrado, D., Barton, E. J., Batista, V., Bellucci, G., Belmonte Avilés, J. A., Berry, D., Bézard, B., Biondi, D., Błęcka, M., Boisse, I., Bonfond, B., Bordé, P., Börner, P., Bouy, H., Brown, L., Buchhave, L., Budaj, J., Bulgarelli, A., Burleigh, M., Cabral, A., Capria, M. T., Cassan, A., Cavarroc, C., Cecchi-Pestellini, C., Cerulli, R., Chadney, J., Chamberlain, S., Charnoz, S., Christian Jessen, N., Ciaravella, A., Claret, A., Claudi, R., Coates, A., Cole, R., Collura, A., Cordier, D., Covino, E., Danielski, C., Damasso, M., Deeg, H. J., Delgado-Mena, E., Del Vecchio, C., Demangeon, O., De Sio, A., De Wit, J., Dobrijévic, M., Doel, P., Dominic, C., Dorfi, E., Eales, S., Eiroa, C., Espinoza Contreras, M., Esposito, M., Eymet, V., Fabrizio, N., Fernández, M., Femenía Castella, B., Figueira, P., Filacchione, G., Fletcher, L., Focardi, M., Fossey, S., Fouqué, P., Frith, J., Galand, M., Gambicorti, L., Gaulme, P., García López, R. J., Garcia-Piquer, A., Gear, W., Gerard, J.-C., Gesa, L., Giani, E., Gianotti, F., Gillon, M., Giro, E., Giuranna, M., Gomez, H., Gomez-Leal, I., Gonzalez Hernandez, J., González Merino, B., Graczyk, R., Grassi, D., Guardia, J., Guio, P., Gustin, J., Hargrave, P., Haigh, J., Hébrard, E., Heiter, U., Heredero, R. L., Herrero, E., Hersant, F., Heyrovsky, D., Hollis, M., Hubert, B., Hueso, R., Israelian, G., Iro, N., Irwin, P., Jacquemoud, S., Jones, G., Jones, H., Justtanont, K., Kehoe, T., Kerschbaum, F., Kerins, E., Kervella, P., Kipping, D., Koskinen, T., Krupp, N., Lahav, O., Laken, B., Lanza, N., Lellouch, E., Leto, G., Licandro Goldaracena, J., Lithgow-Bertelloni, C., Liu, S. J., Lo Cicero, U., Lodieu, N., Lognonné, P., Lopez-Puertas, M., Lopez-Valverde, M. A., Lundgaard Rasmussen, I., Luntzer, A., Machado, P., MacTavish, C., Maggio, A., Maillard, J.-P., Magnes, W., Maldonado, J., Mall, U., Marquette, J.-B., Mauskopf, P., Massi, F., Maurin, A.-S., Medvedev, A., Michaut, C., Miles-Paez, P., Montalto, M., Montañés Rodríguez, P., Monteiro, M., Montes, D., Morais, H., Morales, J. C., Morales-Calderón, M., Morello, G., Moro Martín, A., Moses, J., Moya Bedon, A., Murgas Alcaino, F., Oliva, E., Orton, G., Palla, F., Pancrazzi, M., Pantin, E., Parmentier, V., Parviainen, H., Peña Ramírez, K. Y., Peralta, J., Perez-Hoyos, S., Petrov, R., Pezzuto, S., Pietrzak, R., Pilat-Lohinger, E., Piskunov, N., Prinja, R., Prisinzano, L., Polichtchouk, I., Poretti, E., Radioti, A., Ramos, A. A., Rank-Lüftinger, T., Read, P., Readorn, K., Rebolo López, R., Rebordão, J., Rengel, M., Rezac, L., Rocchetto, M., Rodler, F., Sánchez Béjar, V. J., Sanchez Lavega, A., Sanromá, E., Santos, N., Sanz Forcada, J., Scandariato, G., Schmider, F.-X., Scholz, A., Scuderi, S., Sethenadh, J., Shore, S., Showman, A., Sicardy, B., Sitek, P., Smith, A., Soret, L., Sousa, S., Stiepen, A., Stolarski, M., Strazzulla, G., Tabernero, H. M., Tanga, P., Tecsa, M., Temple, J., Terenzi, L., Tessenyi, M., Testi, L., Thompson, S., Thrastarson, H., Tingley, B. W., Trifoglio, M., Martín Torres, J., Tozzi, A., Turrini, D., Varley, R., Vakili, F., de Val-Borro, M., Valdivieso, M. L., Venot, O., Villaver, E., Vinatier, S., Viti, S., Waldmann, I., Waltham, D., Ward-Thompson, D., Waters, R., Watkins, C., Watson, D., Wawer, P., Wawrzaszk, A., White, G. J., Widemann, T., Winek, W., Wiśniowski, T., Yelle, R., Yung, Y., and Yurchenko, S. N.

Abstract

The discovery of almost two thousand exoplanets has revealed an unexpectedly diverse planet population. We see gas giants in few-day orbits, whole multi-planet systems within the orbit of Mercury, and new populations of planets with masses between that of the Earth and Neptune—all unknown in the Solar System. Observations to date have shown that our Solar System is certainly not representative of the general population of planets in our Milky Way. The key science questions that urgently need addressing are therefore: What are exoplanets made of? Why are planets as they are? How do planetary systems work and what causes the exceptional diversity observed as compared to the Solar System? The EChO (Exoplanet Characterisation Observatory) space mission was conceived to take up the challenge to explain this diversity in terms of formation, evolution, internal structure and planet and atmospheric composition. This requires in-depth spectroscopic knowledge of the atmospheres of a large and well-defined planet sample for which precise physical, chemical and dynamical information can be obtained. In order to fulfil this ambitious scientific program, EChO was designed as a dedicated survey mission for transit and eclipse spectroscopy capable of observing a large, diverse and well-defined planet sample within its 4-year mission lifetime. The transit and eclipse spectroscopy method, whereby the signal from the star and planet are differentiated using knowledge of the planetary ephemerides, allows us to measure atmospheric signals from the planet at levels of at least 10−4 relative to the star. This can only be achieved in conjunction with a carefully designed stable payload and satellite platform. It is also necessary to provide broad instantaneous wavelength coverage to detect as many molecular species as possible, to probe the thermal structure of the planetary atmospheres and to correct for the contaminating effects of the stellar photosphere. This requires

48. Simultaneous Cassini VIMS and UVIS observations of Saturn's southern aurora: Comparing emissions from H, H2and H3+at a high spatial resolution

Author

Melin, H., Stallard, T., Miller, S., Gustin, J., Galand, M., Badman, S. V., Pryor, W. R., O'Donoghue, J., Brown, R. H., and Baines, K. H.

Abstract

Here, for the first time, temporally coincident and spatially overlapping Cassini VIMS and UVIS observations of Saturn's southern aurora are presented. Ultraviolet auroral H and H2emissions from UVIS are compared to infrared H3+emission from VIMS. The auroral emission is structured into three arcs – H, H2and H3+are morphologically identical in the bright main auroral oval (∼73°S), but there is an equatorward arc that is seen predominantly in H (∼70°S), and a poleward arc (∼74°S) that is seen mainly in H2and H3+. These observations indicate that, for the main auroral oval, UV emission is a good proxy for the infrared H3+morphology (and vice versa), but for emission either poleward or equatorward this is no longer true. Hence, simultaneous UV/IR observations are crucial for completing the picture of how the atmosphere interacts with the magnetosphere. Main auroral oval is morphologically very similar in the UV as the IREquatorward and poleward of the main oval there are strong UV/IR differencesProof of concept for simultaneous VIMS/UVIS observations

Published
2011
Full Text
View/download PDF

50. Chemical and Genetic Modulation of Complex I of the Electron Transport Chain Enhances the Biotherapeutic Protein Production Capacity of CHO Cells.

Author

Kretzmer C, Reger K, Balassi V, Pham QL, Johns M, Peters ST, Petersen A, Mahadevan J, Gustin J, Borgschulte T, and Razafsky D

Subjects
Cricetinae, Animals, Humans, CHO Cells, Bromodeoxyuridine metabolism, Electron Transport, Recombinant Proteins metabolism, Cricetulus
Abstract

Chinese hamster ovary (CHO) cells are the cell line of choice for producing recombinant therapeutic proteins. Despite improvements in production processes, reducing manufacturing costs remains a key driver in the search for more productive clones. To identify media additives capable of increasing protein production, CHOZN ® GS -/- cell lines were screened with 1280 small molecules, and two were identified, forskolin and BrdU, which increased productivity by ≥40%. While it is possible to incorporate these small molecules into a commercial-scale process, doing so may not be financially feasible or could raise regulatory concerns related to the purity of the final drug substance. To circumvent these issues, RNA-Seq was performed to identify transcripts which were up- or downregulated upon BrdU treatment. Subsequent Reactome pathway analysis identified the electron transport chain as an affected pathway. CRISPR/Cas9 was utilized to create missense mutations in two independent components of the electron transport chain and the resultant clones partially recapitulated the phenotypes observed upon BrdU treatment, including the productivity of recombinant therapeutic proteins. Together, this work suggests that BrdU can enhance the productivity of CHO cells by modulating cellular energetics and provides a blueprint for translating data from small molecule chemical screens into genetic engineering targets to improve the performance of CHO cells. This could ultimately lead to more productive host cell lines and a more cost-effective method of supplying medication to patients.

Published
2023
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results