1. Gender differences and management of stroke risk of nonvalvular atrial fibrillation in an upper middle-income country: Insights from the CARMEN-AF registry
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J. Antonio González-Hermosillo, Manuel A. Baños-González, Milton E. Guevara-Valdivia, Jorge A. Vázquez-Acosta, Manuel Odín de los Ríos Ibarra, Kulio A. Aguilar-Linares, Carlos Cantú-Brito, José L. Leiva-Pons, Gerardo Pozas-Garza, Eddie A. Favela-Pérez, Manlio F. Márquez, María Sangeado Santos, César González Aguilar, Jorge Gómez Flores, Karim Yarek Juárez Escobar, Samantha Rodríguez Bastidas, José Raúl de los Ríos Ibarra, Carmen Summerson Lama, José Paz Marcelo Jiménez Cruz, Enrique Martínez Flores, Norberto Matadamas Hernández, Vanesa Esperanza Matadamas Carmona, Candelaria Mancilla, Rocío Camacho Casillas, José Refugio Ramírez González, Reynaldo Magaña Magaña, Jorge Carrillo Calvillo, Ulises Rojel Martínez, Marco Antonio Alcocer Gamba, Héctor Francisco Fernández Saldaña, Laura Reséndiz Barrón, Susano Lara Vaca, Edgar Alfredo Rodríguez Salazar, Humberto Rodríguez Reyes, Marco Aurelio Islava Gálvez, José Salvador Lainez Zelaya, Lidia Evangelina Betancourt Hernández, Yoloxochitl García Jiménez, Sadoc Marín Rendon, Nicolás Reyes Reyes, Luis Gerardo Molina Fernández de Lara, Carlos Gutiérrez González, Fernando Flores Silva, Alberto Zenón Baños Velasco, Miguel Ernesto Beltrán Gámez, Amanda Castelán Ojeda, César Iván Vázquez Serna, Miguel Ángel Negrete Rivera, Alejandro Lechuga Martín del Campo, Demetrio Kosturakis García, Ramón Miguel Esturau Santaló, José Luis Novelo Del Valle, Luis Delgado Leal, Luis Ángel Trujillo Muñoz, José Fabián Hernández Díaz, Mariano Miguel Guerra, Raúl Isaac Márquez, María Isabel Sánchez Ramírez, Marcos Robledo, José Manuel Enciso Muñoz, Juan Carlos Núñez Fragoso, and Saúl Flores
- Subjects
Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Background: Atrial Fibrillation (AF) is associated with an increased risk of stroke and systemic embolism. Several studies have suggested that female AF patients could have a greater risk for stroke. There is scarce information about clinical characteristics and use of antithrombotic therapies in Latin American patients with nonvalvular AF. Objective: To describe the gender differences in clinical characteristics, thromboembolic risk, and antithrombotic therapy of patients with nonvalvular AF recruited in Mexico, an upper middle-income country, into the prospective national CARMEN-AF Registry. Methods: A total of 1423 consecutive patients, with at least one thromboembolic risk factor were enrolled in CARMEN-AF Registry during a three-year period (2014–2017). They were categorized according to Gender. Results: Overall, 48.6% were women, mean age 70 ± 12 years. Diabetes, smoking, alcoholism, non-ischemic cardiomyopathy, coronary artery disease, and obstructive sleep apnea were higher in men. Most women were found with paroxysmal AF (40.6%), and most men with permanent AF (44.0%). No gender differences were found in the use of vitamin K antagonists (VKA) (30.5% in women vs. 28.0% in men). No gender differences were found in the use of direct oral anticoagulants (DOAC) (33.8% women vs 35.4% men). Conclusions: CARMEN-AF Registry demonstrates that in Mexico, regardless of gender, a large proportion of patients remain undertreated. No gender differences were found in the use of VKA or DOAC. Keywords: Atrial fibrillation, Gender, Thromboembolic risk, Antithrombotic therapy, Stroke, Mexico
- Published
- 2019
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