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3 results on '"Heinrich, Michaela"'

1. Inanspruchnahme von Gesundheitsleistungen und Versorgungsqualität aus Perspektive der Eltern - Ergebnisse der multizentrischen, prospektiven Beobachtungsstudie ICON zur juvenilen idiopathischen Arthritis

Author

Heinrich, Michaela, Listing, Miriam, Niewerth, Martina, Liedmann, Ina, Rohr, Irena, Horneff, Gerd, Foeldvari, Ivan, Haas, Johannes Peter, Hospach, Anton, and Weller-Heinemann, Frank

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Einleitung: Die juvenile idiopathische Arthritis (JIA) ist mit einer Prävalenz von 0,1% eine der häufigsten chronischen Erkrankungen im Kindes- und Jugendalter. Sie stellt für Patienten und für die Familie eine große Herausforderung dar, da über die körperlichen[zum vollständigen Text gelangen Sie über die oben angegebene URL], 45. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 31. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh), 27. Jahrestagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)

Published
2017
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2. Y-box protein-1/p18 as novel serum marker for ovarian cancer diagnosis: A study by the Tumor Bank Ovarian Cancer (TOC)

Author

Rohr, Irena, primary, Braicu, Elena I., additional, En-Nia, Abdelaziz, additional, Heinrich, Michaela, additional, Richter, Rolf, additional, Chekerov, Radoslav, additional, Dechend, Ralf, additional, Heidecke, Harald, additional, Dragun, Duska, additional, Schäfer, Reinhold, additional, Gorny, Xenia, additional, Lindquist, Jonathan A., additional, Brandt, Sabine, additional, Sehouli, Jalid, additional, and Mertens, Peter R., additional

Published
2016
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3. Role of IGF-I in Primary Ovarian Cancer - A Study of the OVCAD European Consortium.

Author

Rohr I, Zeillinger R, Heinrich M, Concin N, Vergote I, Nassir M, Mahner S, VAN Nieuwenhuysen E, Trillsch F, Cacsire-Tong D, Chekerov R, Sehouli J, and Braicu EI

Subjects
Adult, Aged, Aged, 80 and over, CA-125 Antigen metabolism, Carcinoma, Ovarian Epithelial, Cytoreduction Surgical Procedures, Female, Humans, Membrane Proteins metabolism, Middle Aged, Neoplasm Staging, Neoplasms, Glandular and Epithelial metabolism, Organoplatinum Compounds therapeutic use, Ovarian Neoplasms metabolism, Prognosis, Survival Analysis, Young Adult, Insulin-Like Growth Factor I metabolism, Neoplasms, Glandular and Epithelial pathology, Neoplasms, Glandular and Epithelial therapy, Ovarian Neoplasms pathology, Ovarian Neoplasms therapy, Up-Regulation
Abstract

Background/aim: IGF-I (insulin growth factor 1) is crucially involved in cellular proliferation. Moreover, deregulation of IGF-I has been shown to be relevant in the carcinogenesis of various tumor entities. However, the impact of IGF-I in epithelial ovarian cancer (EOC) is unclear. In the present study, we investigated the predictive and prognostic role of circulatory IGF-I in primary EOC patients., Patients and Methods: In the FP6 European Project "OVCAD", 275 consecutive primary EOC patients were enrolled. Patients were eligible if radical cytoreductive surgery and platinum-based chemotherapy were performed. Plasma IGF-I was detected using ELISA., Results: Increased plasma IGF-I levels were more frequently found in well-differentiated epithelial ovarian carcinoma (p=0.0047). A weak correlation was observed between IGF-I levels and CA-125 in patients with serous EOC (p=0.04). No association between IGF-I expression and other clinico-pathological parameters was observed., Conclusion: IGF-I is overexpressed in patients with well-differentiated EOC. Further studies are warranted to elucidate the role of IGF-I in this sub-group of patients., (Copyright© 2016 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved.)

Published
2016

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