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4. Renal Health Through Medicine–Food Homology: A Comprehensive Review of Botanical Micronutrients and Their Mechanisms.

Author

Zhao, Yi, Song, Jian-Ye, Feng, Ru, Hu, Jia-Chun, Xu, Hui, Ye, Meng-Liang, Jiang, Jian-Dong, Chen, Li-Meng, and Wang, Yan

Abstract

Background: As an ancient concept and practice, "food as medicine" or "medicine–food homology" is receiving more and more attention these days. It is a tradition in many regions to intake medicinal herbal food for potential health benefits to various organs and systems including the kidney. Kidney diseases usually lack targeted therapy and face irreversible loss of function, leading to dialysis dependence. As the most important organ for endogenous metabolite and exogenous nutrient excretion, the status of the kidney could be closely related to daily diet. Therefore, medicinal herbal food rich in antioxidative, anti-inflammation micronutrients are ideal supplements for kidney protection. Recent studies have also discovered its impact on the "gut–kidney" axis. Methods: Here, we review and highlight the kidney-protective effects of botanicals with medicine–food homology including the most frequently used Astragalus membranaceus and Angelica sinensis (Oliv.) Diels, concerning their micronutrients and mechanism, offering a basis and perspective for utilizing and exploring the key substances in medicinal herbal food to protect the kidney. Results: The index for medicine–food homology in China contains mostly botanicals while many of them are also consumed by people in other regions. Micronutrients including flavonoids, polysaccharides and others present powerful activities towards renal diseases. Conclusions: Botanicals with medicine–food homology are widely speeded over multiple regions and incorporating these natural compounds into dietary habits or as supplements shows promising future for renal health. [ABSTRACT FROM AUTHOR]

Published
2024
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7. Metabolites Analysis of Anti-Myocardial Ischemia Active Components of Saussurea involucrata Based on Gut Microbiota—Drug Interaction

Author

Yu, Hang, primary, Fu, Jie, additional, Guo, Hui-Hui, additional, Pan, Li-Bin, additional, Xu, Hui, additional, Zhang, Zheng-Wei, additional, Hu, Jia-Chun, additional, Yang, Xin-Yu, additional, Zhang, Hao-Jian, additional, Bu, Meng-Meng, additional, Lin, Yuan, additional, Jiang, Jian-Dong, additional, and Wang, Yan, additional

Published
2022
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8. Biotransformation of Liquiritigenin into Characteristic Metabolites by the Gut Microbiota

Author

Keranmu, Adili, primary, Pan, Li-Bin, additional, Fu, Jie, additional, Han, Pei, additional, Yu, Hang, additional, Zhang, Zheng-Wei, additional, Xu, Hui, additional, Yang, Xin-Yu, additional, Hu, Jia-Chun, additional, Zhang, Hao-Jian, additional, Bu, Meng-Meng, additional, Jiang, Jian-Dong, additional, Xing, Nian-Zeng, additional, and Wang, Yan, additional

Published
2022
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9. Hydroxyurea ameliorates atherosclerosis in ApoE-/- mice by potentially modulating Niemann-Pick C1-like 1 protein through the gut microbiota

Author

Yang, Xin-Yu, primary, Yu, Hang, additional, Fu, Jie, additional, Guo, Hui-Hui, additional, Han, Pei, additional, Ma, Shu-Rong, additional, Pan, Li-Bin, additional, Zhang, Zheng-Wei, additional, Xu, Hui, additional, Hu, Jia-Chun, additional, Zhang, Hao-Jian, additional, Bu, Meng-Meng, additional, Zhang, Xian-Feng, additional, Yang, Wei, additional, Wang, Jing-Yue, additional, Jin, Jing-Yu, additional, Zhang, Hui-Cong, additional, Li, Dong-Rui, additional, Lu, Jin-Yue, additional, Lin, Yuan, additional, Jiang, Jian-Dong, additional, Tong, Qian, additional, and Wang, Yan, additional

Published
2022
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11. The pharmacokinetic study of Saussurea involucrataliquid tonic, a traditional Chinese patent for inflammatory pain, in female rats in breastfeeding period

Author

Yu, Hang, Liu, Xing-Tong, Xu, Hui, Zhang, Zheng-Wei, Hu, Jia-Chun, Lu, Jin-Yue, Fu, Jie, Bu, Meng-Meng, Yang, Xin-Yu, Jiang, Quan, and Wang, Yan

Abstract

•The safety of Saussurea involucrataliquid tonic for postpartum medication was evaluated for the first time.•The pharmacokinetic characteristics and milk distribution of main components of Saussurea involucrataliquid tonic were conducted.•The quantitative method for detecting the main components of Saussurea involucrataliquid tonic in the matrix of milk by LC-MS/MS was established.

Published
2023
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