1. Dental Hygienists' Awareness of Medication-Related Osteonecrosis of the Jaw in Private Dental Clinics in Japan.
- Author
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Iijima, Yosuke, Yamada, Miki, Amano, Mai, Watanabe, Saya, Fujimaru, Miki, Uematsu, Ayako, Hino, Shunsuke, Sano, Motohiko, Horie, Norio, Sakagami, Hiroshi, and Kaneko, Takahiro
- Subjects
DENTAL hygienists ,FISHER exact test ,CANCER hospitals ,DENTAL clinics ,DENTAL care - Abstract
Purpose: Medication-related osteonecrosis of the jaw (MRONJ) caused by bisphosphonates (BPs) and denosumab (Dmab) is still a major oral adverse event caused by cancer treatment and may be under-recognized by private dental services. With the aim of reducing the prevalence of MRONJ, this study, which is a pilot study for a planned future large-scale survey, compared knowledge about MRONJ between dental hygienists (DHs) in private dental clinics and those in cancer center hospitals. Methods: We conducted a questionnaire-based survey regarding MRONJ between 1 November 2023 and 31 January 2024 on DHs at a cancer base hospital and a private clinic in Saitama, Japan. We statistically analyzed the data collected using the χ
2 test or Fisher's exact test with the level of significance set at 5%. Results: This study included 10 in-hospital and 53 private clinic DHs. The in-hospital DHs had appropriate knowledge of MRONJ. However, compared with the in-hospital DHs, although the private clinic DHs knew that BPs are used for osteoporosis, significantly fewer had knowledge of Dmab (p <.001) or knew that BPs and Dmab could also be used to treat cancer (both p <.001). In addition, few private clinic DHs were aware of MRONJ cases refractory to antibiotic treatment alone (p =.012). Conclusion: These findings suggest that private clinic DHs have less knowledge of MRONJ than those in cancer base hospitals. [ABSTRACT FROM AUTHOR]- Published
- 2024
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