1. VALIDation of the IBD-Disk Instrument for Assessing Disability in Inflammatory Bowel Diseases in a French Cohort: The VALIDate Study
- Author
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Laurent Siproudhis, Guillaume Bouguen, Pierre-Antoine Gourraud, Mathurin Flamant, Arnaud Bourreille, Caroline Trang-Poisson, Thomas Goronflot, Matthieu Hanf, Elodie Cesbron-Métivier, Alexandra Poinas, Elise Kerdreux, Catherine Le Berre, Marie Dewitte, Nina Dib, Institut des Maladies de l’Appareil Digestif et Oncologie Digestive [CHU Nantes] (Hôtel Dieu), Hôtel-Dieu de Nantes-Centre hospitalier universitaire de Nantes (CHU Nantes), Centre hospitalier universitaire de Nantes (CHU Nantes), Centre d'Investigation Clinique [Rennes] (CIC), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM), CHU Pontchaillou [Rennes], Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM), Hémodynamique, Interaction Fibrose et Invasivité tumorales Hépatiques (HIFIH), Université d'Angers (UA), Centre de Recherche en Transplantation et Immunologie (U1064 Inserm - CRTI), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN), and Université de Rennes (UR)-Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM)
- Subjects
Adult ,Male ,Crohn’s disease ,medicine.medical_specialty ,[SDV]Life Sciences [q-bio] ,Concurrent validity ,Disease ,Severity of Illness Index ,Inflammatory bowel disease ,digestive system ,Disability Evaluation ,03 medical and health sciences ,0302 clinical medicine ,Cost of Illness ,Crohn Disease ,Cronbach's alpha ,Internal medicine ,Activities of Daily Living ,medicine ,Humans ,Patient Reported Outcome Measures ,ulcerative colitis ,Crohn's disease ,Patient-reported outcomes ,business.industry ,Gastroenterology ,Reproducibility of Results ,General Medicine ,medicine.disease ,Faecal calprotectin ,Ulcerative colitis ,digestive system diseases ,3. Good health ,Research Design ,030220 oncology & carcinogenesis ,Cohort ,Quality of Life ,Colitis, Ulcerative ,Female ,030211 gastroenterology & hepatology ,France ,business - Abstract
Background and Aims Inflammatory bowel diseases [IBD] are disabling disorders. The IBD-Disability Index [IBD-DI] was developed for quantifying disability in IBD patients but is difficult to use. The IBD-Disk is a visual adaptation of the IBD-DI. It has not been validated yet. The main objectives were to validate the IBD-Disk and to assess the clinical factors associated with a change in the score and its variability over time. Methods From May 2018 to July 2019, IBD patients from three university-affiliated hospitals responded twice to both IBD-Disk and IBD-DI at 3–12 month intervals. Validation included concurrent validity, reproducibility, and internal consistency. Mean IBD-Disk scores were compared according to clinical factors. Variability was assessed by comparing scores between baseline and follow-up visits. Results A total of 447 patients [71% Crohn’s disease, 28% ulcerative colitis] were included in the analysis at baseline and 265 at follow-up. There was a good correlation between IBD-Disk and IBD-DI [r = 0.75, p Conclusions This study validated the IBD-Disk in a large cohort of IBD patients, demonstrating that it is a valid and reliable tool for quantifying disability for both CD and UC.
- Published
- 2020
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