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4. Observational concepts and experience

Author

Ivanov, Ivan V.

Subjects
153, BD Speculative Philosophy
Abstract

The thesis is intended to contribute to the growing understanding of the indispensable role played by phenomenal consciousness in human cognition, and specifically in making our concepts of the external world available. The focus falls on so called observational concepts, a type of rudimentary, perceptually-based objective concepts in our repertoire — picking out manifest properties such as colors and shapes. A theory of such concepts gets provided, and, consequently, the exact role that perceptual consciousness plays in making concepts of this sort available gets settled. In the first half of the thesis, observational concepts get construed as a special type of recognitional concepts. On an analogy with perceptual demonstratives, having such concepts would involve having non-trivial knowledge of their reference. The experiential basis of such concepts would, among other things, provide for such constitutive knowledge. The theoretical background relevant to the hypothesis gets provided in the first chapter. A defence of the hypothesis follows in the second. In the second half of the thesis, care is taken to distinguish among two ways in which the constitutive knowledge of the reference of an observational concept could be fleshed out. In the third chapter, perceptual experience is shown to provide the basis both for knowledge of observational properties by acquaintance, and for knowledge of the essence of such properties — provided that knowledge of essence gets construed in the right, modest way. It might be natural to take knowledge by acquaintance to be the sort relevant to observational concept possession, especially given that in the case of perceptual demonstratives this is the role likely played by experience. However, this initial impression proves to be mistaken. The constitutive knowledge of the referent of an observational concept turns out to consist in the capacity to determine a priori the essence of the respective property. To show this, an argument gets provided in the penultimate fourth chapter, based on the key role played by experiences of instances of observational properties in optimal viewing conditions in enabling the possession of the respective observational concept.

Published
2016

8. Exploring Coumarin-Based Boron Emissive Complexes as Temperature Thermometers in Polymer-Supported Materials

Author

Pedro, Gonçalo, primary, Duarte, Frederico, additional, Cheptsov, Dmitrii A., additional, Volodin, Nikita Yu., additional, Ivanov, Ivan V., additional, Santos, Hugo M., additional, Capelo-Martinez, Jose Luis, additional, Cuerva, Cristián, additional, Oliveira, Elisabete, additional, Traven, Valerii F., additional, and Lodeiro, Carlos, additional

Published
2023
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10. Synthesis and Characterization of Novel 2-Acyl-3-trifluoromethylquinoxaline 1,4-Dioxides as Potential Antimicrobial Agents

Author

Buravchenko, Galina I., primary, Maslov, Dmitry A., additional, Alam, Md Shah, additional, Grammatikova, Natalia E., additional, Frolova, Svetlana G., additional, Vatlin, Aleksey A., additional, Tian, Xirong, additional, Ivanov, Ivan V., additional, Bekker, Olga B., additional, Kryakvin, Maxim A., additional, Dontsova, Olga A., additional, Danilenko, Valery N., additional, Zhang, Tianyu, additional, and Shchekotikhin, Andrey E., additional

Published
2022
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12. Comparison of analgesic efficacy and fetal effects between transdermal administration of fentanyl and intramuscular administration of buprenorphine in pregnant sheep

Author

Padgett, Ashley L., primary, Lepiz, Mauricio L., additional, Mackay, Evelyn E., additional, Driskill, Austin J., additional, Ivanov, Ivan V., additional, Fajt, Virginia R., additional, Konarik, Megan M., additional, Mays, Travis P., additional, and Washburn, Shannon E., additional

Published
2020
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15. A framework for grouping nanoparticles based on their measurable characteristics

Author

Sayes,Christie M, Smith,P Alex, Ivanov,Ivan V, Sayes,Christie M, Smith,P Alex, and Ivanov,Ivan V

Abstract

Christie M Sayes,1–3 P Alex Smith,2 Ivan V Ivanov3 1Center for Aerosol and Nanomaterials Engineering, RTI International, Research Triangle Park, NC, USA; 2Department of Biomedical Engineering, 3Department of Veterinary Physiology and Pharmacology, Texas A&M University, College Station, TX, USA Background: There is a need to take a broader look at nanotoxicological studies. Eventually, the field will demand that some generalizations be made. To begin to address this issue, we posed a question: are metal colloids on the nanometer-size scale a homogeneous group? In general, most people can agree that the physicochemical properties of nanomaterials can be linked and related to their induced toxicological responses. Methods: The focus of this study was to determine how a set of selected physicochemical properties of five specific metal-based colloidal materials on the nanometer-size scale – silver, copper, nickel, iron, and zinc – could be used as nanodescriptors that facilitate the grouping of these metal-based colloids. Results: The example of the framework pipeline processing provided in this paper shows the utility of specific statistical and pattern recognition techniques in grouping nanoparticles based on experimental data about their physicochemical properties. Interestingly, the results of the analyses suggest that a seemingly homogeneous group of nanoparticles could be separated into sub-groups depending on interdependencies observed in their nanodescriptors. Conclusion: These particles represent an important category of nanomaterials that are currently mass produced. Each has been reputed to induce toxicological and/or cytotoxicological effects. Here, we propose an experimental methodology coupled with mathematical and statistical modeling that can serve as a prototype for a rigorous framework that aids in the ability to group nanomaterials together and to facilitate the subsequent analysis of trends in data based on quanti

Published
2013

18. Observational concepts and experience

Author

Ivanov, Ivan V.

Subjects
BD
Abstract

The thesis is intended to contribute to the growing understanding of the indispensable role played by phenomenal consciousness in human cognition, and specifically in making our concepts of the external world available. The focus falls on so called observational concepts, a type of rudimentary, perceptually-based objective concepts in our repertoire — picking out manifest properties such as colors and shapes. A theory of such concepts gets provided, and, consequently, the exact role that perceptual consciousness plays in making concepts of this sort available gets settled.\ud \ud In the first half of the thesis, observational concepts get construed as a special type of recognitional concepts. On an analogy with perceptual demonstratives, having such concepts would involve having non-trivial knowledge of their reference. The experiential basis of such concepts would, among other things, provide for such constitutive knowledge. The theoretical background relevant to the hypothesis gets provided in the first chapter. A defence of the hypothesis follows in the second.\ud \ud In the second half of the thesis, care is taken to distinguish among two ways in which the constitutive knowledge of the reference of an observational concept could be fleshed out. In the third chapter, perceptual experience is shown to provide the basis both for knowledge of observational properties by acquaintance, and for knowledge of the essence of such properties — provided that knowledge of essence gets construed in the right, modest way.\ud \ud It might be natural to take knowledge by acquaintance to be the sort relevant to observational concept possession, especially given that in the case of perceptual demonstratives this is the role likely played by experience. However, this initial impression proves to be mistaken. The constitutive knowledge of the referent of an observational concept turns out to consist in the capacity to determine a priori the essence of the respective property. To show this, an argument gets provided in the penultimate fourth chapter, based on the key role played by experiences of instances of observational properties in optimal viewing conditions in enabling the possession of the respective observational concept.

19. A framework for grouping nanoparticles based on their measurable characteristics.

Author

Sayes CM, Smith PA, and Ivanov IV

Subjects
Discriminant Analysis, Hydrogen-Ion Concentration, Principal Component Analysis, Structure-Activity Relationship, Surface Properties, Colloids chemistry, Metal Nanoparticles chemistry, Metals, Heavy chemistry
Abstract

Background: There is a need to take a broader look at nanotoxicological studies. Eventually, the field will demand that some generalizations be made. To begin to address this issue, we posed a question: are metal colloids on the nanometer-size scale a homogeneous group? In general, most people can agree that the physicochemical properties of nanomaterials can be linked and related to their induced toxicological responses., Methods: The focus of this study was to determine how a set of selected physicochemical properties of five specific metal-based colloidal materials on the nanometer-size scale - silver, copper, nickel, iron, and zinc - could be used as nanodescriptors that facilitate the grouping of these metal-based colloids., Results: The example of the framework pipeline processing provided in this paper shows the utility of specific statistical and pattern recognition techniques in grouping nanoparticles based on experimental data about their physicochemical properties. Interestingly, the results of the analyses suggest that a seemingly homogeneous group of nanoparticles could be separated into sub-groups depending on interdependencies observed in their nanodescriptors., Conclusion: These particles represent an important category of nanomaterials that are currently mass produced. Each has been reputed to induce toxicological and/or cytotoxicological effects. Here, we propose an experimental methodology coupled with mathematical and statistical modeling that can serve as a prototype for a rigorous framework that aids in the ability to group nanomaterials together and to facilitate the subsequent analysis of trends in data based on quantitative modeling of nanoparticle-specific structure-activity relationships. The computational part of the proposed framework is rather general and can be applied to other groups of nanomaterials as well.

Published
2013
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