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16 results on '"Kassar, Olfa"'

1. PB1749: COMPARATIVE STUDY OF B AND T-ALL IN CHILDREN, ADOLESCENTS, AND YOUNG ADULTS: CLINICAL CHARACTERISTICS AND THERAPEUTIC RESULTS

Author

Frikha, Imen, primary, Kahla, Aicha Ben, additional, Medhaffer, Moez, additional, Louati, Nour, additional, Amor, Imen Ben, additional, Kassar, Olfa, additional, Khalifa, Latifa, additional, Charfi, Maha, additional, Kallel, Faten, additional, Mallek, Rahma, additional, Hdijji, Sondes, additional, Amor, Ikram Ben, additional, Mnif, Hela, additional, and Elloumi, Moez, additional

Published
2023
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2. PB1907: EPIDEMIOLOGICAL PROFILE AND DIAGNOSTIC FEATURES OF ACUTE MYELOBLASTIC LEUKEMIA IN ADULTS: EXPERIENCE OF THE HEMATOLOGY DEPARTMENT OF SFAX

Author

Siala, Nour, primary, Derbel, Yousra Fakhfakh, additional, Amor, Imen Ben, additional, Chaari, Mourad, additional, Kassar, Olfa, additional, Jdidi, Ines, additional, Frikha, Imen, additional, Louati, Nour, additional, Kallel, Faten, additional, Charfi, Maha, additional, Sannena, Hlima, additional, Mnif, Samia, additional, Latifa, Khelifa, additional, Mallek, Rahma, additional, Mseddi, Sondes Hadiji, additional, Medhaffar, Moez, additional, Saad, Ali, additional, Amor, Ikram Ben, additional, Kallel, Choumous, additional, and Elloumi, Moez, additional

Published
2023
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4. PB1732: CLINICAL CHARACTERISTICS AND THERAPEUTIC RESULTS OF CHILDHOOD AND YOUNG ADULTS T - ACUTE LYMPHOBLASTIC LEUKEMIA IN SOUTH OF TUNISIA

Author

Frikha, Imen, primary, Kahla, Aicha Ben, additional, Medhaffer, Moez, additional, Louati, Nour, additional, Amor, Imen Ben, additional, Khalifa, Latifa, additional, Kassar, Olfa, additional, Fakhfakh, Yossra, additional, Kallel, Faten, additional, Charfi, Maha, additional, Hdijji, Sondes, additional, Elloumi, Moez, additional, and Amor, Ikram Ben, additional

Published
2023
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5. PB1891: EARLY DEATH IN ACUTE PROMYELOCYTIC LEUKEMIA IN SOUTHERN TUNISIA

Author

Koubaa, Asma, primary, Kassar, Olfa, additional, Charfi, Maha, additional, Derbel, Yousra Fakhfakh, additional, Kallel, Faten, additional, Frikha, Imen, additional, Amor, Imen Ben, additional, Khalifa, Latifa, additional, Mallek, Rahma, additional, Medhaffar, Moez, additional, Hdiji, Sondes, additional, and Elloumi, Moez, additional

Published
2023
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7. PB2650: ALLOANTIBODIES IN VON WILLEBRAND DISEASE: ABOUT 6 CASES IN SOUTHERN TUNISIA

Author

Chalbaoui, Amal, primary, Mallek, Rahma, additional, Megdiche, Fatma, additional, Kallel, Faten, additional, Krichen, Imen, additional, Hdiji, Sondes, additional, Kassar, Olfa, additional, Frikha, Imen, additional, Charfi, Maha, additional, Amor, Imen Ben, additional, Fakhfekh, Yosra, additional, Khelifa, Latifa, additional, Moez, Medhaffar, additional, Kallel, Choumous, additional, and Elloumi, Moez, additional

Published
2023
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8. PB1876: SIXTEEN YEARS OF EXPERIENCE WITH THE MRC-10 PROTOCOL FOR THE TREATMENT OF ADULT ACUTE MYELOID LEUKEMIA IN THE SOUTH OF TUNISIA

Author

Siala, Nour, primary, Derbel, Yousra Fakhfakh, additional, Amor, Imen Ben, additional, Rekik, Taicir, additional, Kassar, Olfa, additional, Frikha, Imen, additional, Kallel, Faten, additional, Charfi, Maha, additional, Mnif, Samia, additional, Mnif, Hela, additional, Latifa, Khelifa, additional, Sennenna, Halima, additional, Mallek, Rahma, additional, Mseddi, Sondes Hadiji, additional, Medhaffar, Moez, additional, Saad, Ali, additional, and Elloumi, Moez, additional

Published
2023
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9. PB1895: CHARACTERISTICS AND OUTCOME OF PEADIATRIC ACUTE PROMYELOCYTIC LEUKEMIA IN SOUTHERN TUNISIA

Author

Koubaa, Asma, primary, Kassar, Olfa, additional, Charfi, Maha, additional, Kallel, Faten, additional, Rekik, Taicir, additional, Fakhfakh, Yousra, additional, Frikha, Imen, additional, Amor, Imen Ben, additional, Khalifa, Latifa, additional, Mallek, Rahma, additional, Medhaffer, Moez, additional, Hdiji, Sondes, additional, Mnif, Hela, additional, and Elloumi, Moez, additional

Published
2023
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14. Invasive pulmonary aspergillosis in patients with acute leukemia.

Author

Kassar O, Ben Kahla A, Fakhefakh Y, Feki W, Cheikhrouhou F, and Elloumi M

Subjects
Humans, Retrospective Studies, Male, Female, Adult, Middle Aged, Tunisia epidemiology, Young Adult, Aged, Tomography, X-Ray Computed, Adolescent, Prevalence, Invasive Pulmonary Aspergillosis epidemiology, Invasive Pulmonary Aspergillosis diagnosis, Invasive Pulmonary Aspergillosis complications, Leukemia, Myeloid, Acute complications, Leukemia, Myeloid, Acute epidemiology, Voriconazole therapeutic use, Antifungal Agents therapeutic use
Abstract

Introduction: Invasive pulmonary aspergillosis is a serious complication in hematology., Aim: Describe the prevalence, diagnostic aspects, therapeutic modalities, and evolution of the IPA cases occurring in patients with acute leukemia., Methods: Our study was retrospective including patients with acute leukemia who developed invasive pulmonary aspergillosis during the period January 2009 and December 2020 at the hematology department in south Tunisia. The IPA was defined in three levels of probability according to the criteria of the EORTC / MSG 2019., Results: We collected 127 patients who presented with Invasive pulmonary aspergillosis. Sixty-three percent of our patients had acute myeloid leukemia. The diagnosis of invasive pulmonary aspergillosis was during the induction course in 76% of cases. Twenty-seven of our patients had chest pain. The chest Computed tomography (CT) scan showed the Halo sign in 89% of cases. The Aspergillus galactomannan antigen was positive in 38% of cases. Extrapulmonary aspergillosis involvement was noted in 18% of cases: IPA was possible and probable respectively in 59% and 41% of cases. All patients treated with Voriconazole with a favorable response in 54% of cases. The mortality rate was 46%. The overall survival at week 12 was 56%., Conclusion: The morbidity and mortality of patients who developed invasive pulmonary aspergillosis with acute leukemia in our series were high. We need to improve our strategy for early diagnosis and management.

Published
2024
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15. Cerebral venous thrombosis after first Methotrexate administration by lumbar puncture in a patient with large B cell lymphoma.

Author

Ben Kahla A, Kassar O, Moalla K, Fakhfakh Y, Hentati Y, and Elloumi M

Subjects
Male, Humans, Spinal Puncture adverse effects, Methotrexate adverse effects, Fatal Outcome, Lymphoma, Large B-Cell, Diffuse complications, Lymphoma, Large B-Cell, Diffuse diagnosis, Lymphoma, Large B-Cell, Diffuse drug therapy, Venous Thrombosis
Abstract

Cerebral venous thrombosis is a rare consequence of lumbar punctures for intrathecal therapy. We report a patient treated for diffuse large B cell lymphoma with cerebral venous thrombosis after intrathecal Methotrexate administration. In this patient, intrathecal treatment was discontinued and he was successfully treated with high-dose low-molecular-weight heparin subcutaneously. Haematologist must be aware about neurological symptoms of cerebral venous thrombosis as a complication of lumbar puncture especially among patients with high coagulopathy state. If neurological symptom occurs, patient should be referred early to neurologist to avoid fatal outcome and neurological deficit.

Published
2023

16. Complexity of diagnosing and treating langerhans cell sarcoma: A case report.

Author

Charfi M, Lajnaf M, Kallel F, Saguem I, Kassar O, and Elloumi M

Subjects
Male, Humans, Middle Aged, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Bleomycin, Dacarbazine therapeutic use, Doxorubicin therapeutic use, Vinblastine therapeutic use, Neoplasm Recurrence, Local, Langerhans Cell Sarcoma diagnosis, Langerhans Cell Sarcoma therapy, Hodgkin Disease diagnosis, Hodgkin Disease therapy
Abstract

Introduction: Langerhans cell sarcoma (LCS) is a very rare malignant tumor of Langerhans cells that may metastasize to many organs. The diagnosis of this tumor is difficult and its prognosis is poor., Aim: To report the difficulty to diagnose LCS, and discuss therapeutic management of this rare entity., Case Presentation: We report a case of LCS in a 52-year-old man who presented with an axillar lymphadenopathy. The diagnosis of nodular sclerosis type Hodgkin's disease was established after histologic examination. The patient was treated with chemotherapy (ABVD regimen: Doxorubicin, Bleomycin, Vinblastine, Dacarbazine) and radiotherapy with a partial response. However, disease recurrence was observed and histological analysis confirmed the diagnosis of Langerhans cell sarcoma. A revision of the initial histological examination concluded to the diagnosis of sarcoma from the beginning. We chose the ESHAP (Etoposide, Methylprednisolone, Aracytine, Cisplatin) regimen and clinical improvement of LCS was obtained after 2 cycles but the patient had a fatal outcome and died by disease progression., Conclusion: Because of its rarity, diagnosis is difficult and an optimal treatment strategy for this disease has not yet been identified. Polychemotherapy can be an effective modality for the treatment of LCS.

Published
2023

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